Echinops telfairi (small Madagascar hedgehog): 101659257
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Entry
101659257 CDS
T08707
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial-like
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
etf
Echinops telfairi (small Madagascar hedgehog)
Pathway
etf00010
Glycolysis / Gluconeogenesis
etf00020
Citrate cycle (TCA cycle)
etf00620
Pyruvate metabolism
etf00785
Lipoic acid metabolism
etf01100
Metabolic pathways
etf01200
Carbon metabolism
etf01210
2-Oxocarboxylic acid metabolism
etf04066
HIF-1 signaling pathway
etf04922
Glucagon signaling pathway
etf05230
Central carbon metabolism in cancer
etf05415
Diabetic cardiomyopathy
Module
etf_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
etf00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
101659257
00020 Citrate cycle (TCA cycle)
101659257
00620 Pyruvate metabolism
101659257
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
101659257
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
101659257
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
101659257
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
101659257
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
101659257
Enzymes [BR:
etf01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
101659257
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Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
101659257
NCBI-ProteinID:
XP_004714917
LinkDB
All DBs
Position
Unknown
AA seq
387 aa
AA seq
DB search
MLAAVSRVLAGAARKPASRVLVASRSFASDATFEIRKCDLHRLEEGPPETAVLTREDGLR
YYKMMQTVRRLELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRAHGF
TFTRGLTVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKY
NGKEEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAASTDYY
KRGDFIPGLRVDGMDVLCVREATKFAAAHCRAGKGPILMELQTYRYHGHSMSDPGVSYRT
REEIQEVRSKSDPIMLLKDRMVNNDLASVEELKEIDVEVRKEIEDAAQFATADPEPPLEE
LGYHIYCNDPPFEVRGANQWIKFKSVS
NT seq
1164 nt
NT seq
+upstream
nt +downstream
nt
atgctcgccgccgtgtcccgcgtgttggcgggcgccgcccggaagccagctagcagagtg
ctggtggcgtcccgtagctttgccagtgacgctacatttgagattaggaaatgcgatctc
caccggctggaggagggcccgcccgagaccgccgtgctcaccagggaggacggccttcgc
tactacaagatgatgcagaccgtccgccgcttggagctgaaggccgaccagctgtacaag
cagaagatcatccgcggcttctgccacctgtgcgatgggcaggaagcgtgctgcgtgggg
ctcgaggccggcataaatcccacggatcatctcatcactgcctatcgggctcacggcttc
acctttacccgggggctcaccgtccgagagatcctggcggagctaactggacgcagagga
ggttgtgcgaaggggaaaggtggttcaatgcacatgtatgccaagaacttctatgggggc
aacggcattgtgggcgcgcaggtgcccttgggggctggaatcgctctggcctgcaagtac
aacggcaaagaggaagtctgcctgaccctttacggggatggtgctgcgaaccagggccag
atatttgaagcttacaatatggcagctttgtggaaactaccgtgcattttcatctgcgaa
aacaaccgttatggaatgggaacgtctgtggagagagcagccgccagcaccgactactac
aagcgaggtgactttattccggggctccgggtagacgggatggatgtcctgtgcgtccgg
gaggctacaaagtttgcagccgcccactgcagagctgggaaggggcccatactgatggag
ctgcagacctaccgctaccacggacacagcatgagcgatcccggagtcagttaccgcacc
cgagaagaaattcaggaagtcagaagtaagagcgaccccattatgcttctcaaggacagg
atggtgaacaacgacctcgccagtgtggaagagctcaaggaaatcgacgtggaagtgaga
aaggaaatcgaggatgcagcccagtttgctacagcagatccggaaccgcctctggaagaa
ctggggtatcacatctactgcaacgacccgccttttgaagttcgtggtgcaaatcagtgg
attaaattcaagtcagtcagttaa
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