Escherichia coli O17 K52 H18 UMN026 (ExPEC): ECUMN_0115
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Entry
ECUMN_0115 CDS
T00831
Symbol
acnB
Name
(GenBank) bifunctional aconitate hydratase 2 and 2-methylisocitrate dehydratase
KO
K01682
aconitate hydratase 2 / 2-methylisocitrate dehydratase [EC:
4.2.1.3
4.2.1.99
]
Organism
eum
Escherichia coli O17:K52:H18 UMN026 (ExPEC)
Pathway
eum00020
Citrate cycle (TCA cycle)
eum00630
Glyoxylate and dicarboxylate metabolism
eum00640
Propanoate metabolism
eum01100
Metabolic pathways
eum01110
Biosynthesis of secondary metabolites
eum01120
Microbial metabolism in diverse environments
eum01200
Carbon metabolism
eum01210
2-Oxocarboxylic acid metabolism
eum01230
Biosynthesis of amino acids
Module
eum_M00009
Citrate cycle (TCA cycle, Krebs cycle)
eum_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
eum_M00012
Glyoxylate cycle
Brite
KEGG Orthology (KO) [BR:
eum00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
ECUMN_0115 (acnB)
00630 Glyoxylate and dicarboxylate metabolism
ECUMN_0115 (acnB)
00640 Propanoate metabolism
ECUMN_0115 (acnB)
Enzymes [BR:
eum01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.3 aconitate hydratase
ECUMN_0115 (acnB)
4.2.1.99 2-methylisocitrate dehydratase
ECUMN_0115 (acnB)
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Gene cluster
GFIT
Motif
Pfam:
Aconitase_2_N
Aconitase_B_N
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
CAR11338
UniProt:
B7N7Y8
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Position
136064..138661
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AA seq
865 aa
AA seq
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MLEEYRKHVAERAAEGIAPKPLDANQMAALVELLKNPPAGEEEFLLDLLTNRVPPGVDEA
AYVKAGFLAAVAKGEAKSPLLTPEKAIELLGTMQGGYNIHPLIDALDDAKLAPIAAKALS
HTLLMFDNFYDVEEKAKAGNEYAKQVMQSWADAEWFLNRPALAEKLTVTVFKVTGETNTD
DLSPAPDAWSRPDIPLHALAMLKNAREGIEPDQPGVVGPIKQIEALQQKGFPLAYVGDVV
GTGSSRKSATNSVLWFMGDDIPHVPNKRGGGLCLGGKIAPIFFNTMEDAGALPIEVDVSN
LNMGDVIDVYPYKGEVRNHETGELLATFELKTDVLIDEVRAGGRIPLIIGRGLTTKAREA
LGLPHSDVFRQAKDVAESDRGFSLAQKMVGRACGVKGIRPGAYCEPKMTSVGSQDTTGPM
TRDELKDLACLGFSADLVMQSFCHTAAYPKPVDVNTHHTLPDFIMNRGGVSLRPGDGVIH
SWLNRMLLPDTVGTGGDSHTRFPIGISFPAGSGLVAFAAATGVMPLDMPESVLVRFKGKM
QPGITLRDLVHAIPLYAIKQGLLTVEKKGKKNIFSGRILEIEGLPDLKVEQAFELTDASA
ERSAAGCTIKLNKEPIIEYLNSNIVLLKWMIAEGYGDRRTLERRIQGMEKWLANPELLEA
DADAEYAAVIDIDLADIKEPILCAPNDPDDARPLSAVQGEKIDEVFIGSCMTNIGHFRAA
GKLLDAHKGQLPTRLWVAPPTRMDAAQLTEEGYYSVFGKSGARIEIPGCSLCMGNQARVA
DGATVVSTSTRNFPNRLGTGANVFLASAELAAVAALIGKLPTPEEYQTYVAQVDKTAVDT
YRYLNFNQLSQYTEKADGVIFQTAV
NT seq
2598 nt
NT seq
+upstream
nt +downstream
nt
gtgctagaagaataccgtaagcacgtagctgagcgtgccgctgaggggattgcgcccaaa
cccctggatgcaaaccaaatggccgcacttgtagagctgctgaaaaacccgcccgcgggc
gaagaagaattcctgttagatctgttaaccaaccgtgttccccctggcgtcgatgaagcc
gcctatgtcaaagcaggcttcctggctgctgtcgcgaaaggcgaagccaaatccccactg
ctgactccggaaaaagccatcgaactgctgggcactatgcagggtggttacaacattcat
ccgctgatcgacgcgctggatgatgccaaactggcaccgatcgctgccaaagcactttct
cacacgctgctgatgttcgataacttctatgacgtagaagagaaagccaaagcaggcaac
gaatatgcgaagcaggtaatgcagtcctgggcggatgccgaatggttcctgaatcgcccg
gcactggctgaaaaactgaccgttaccgtcttcaaagtcacaggcgaaaccaacaccgat
gacctttctccggcaccggatgcgtggtcacgcccggatatcccactgcacgcgctggcg
atgctgaaaaacgcccgtgaaggtattgagccagatcagcctggtgttgttggtccgatc
aaacagattgaagctctgcaacagaaaggtttcccgctggcgtacgtcggtgacgttgtg
ggtacgggttcatcgcgtaaatccgccacgaactccgttctgtggtttatgggcgatgat
attccacatgtgccgaacaaacgcggcggtggtttgtgcctcggcggtaaaattgcaccc
atcttctttaacacgatggaagatgcgggtgcactgccaattgaagtggacgtctctaac
ctgaacatgggtgacgtaattgacgtttacccgtacaaaggtgaagtgcgtaaccacgaa
accggcgaactgctggcgaccttcgaactgaaaaccgacgtgctgattgatgaagtgcgt
gccggtggtcgtattccgctgattatcgggcgtggcctgaccaccaaagcgcgtgaagca
cttggtctgccgcacagcgatgtgttccgtcaggcgaaagatgtcgctgagagcgaccgc
ggcttctcgctggcgcagaaaatggtaggtcgtgcctgcggcgtgaaaggcattcgtccg
ggcgcgtactgcgaaccgaaaatgacttctgtaggttcccaggacaccaccggcccgatg
acccgtgatgaactgaaagacctggcgtgcctgggcttctcggctgacctggtgatgcag
tctttctgccacaccgcggcgtatccgaagccagttgacgtgaacacgcaccacacgctg
ccggacttcattatgaaccgtggtggtgtgtcgctgcgtccgggtgacggcgtaatccac
tcctggctgaaccgtatgctgctgccggataccgtcggtaccggtggtgactcccatacc
cgtttcccgatcggcatttctttcccggcgggttctggtctggtggcatttgcagccgca
acaggcgtaatgccgctggatatgccggaatccgttctggtgcgcttcaaaggcaaaatg
cagccgggcatcaccctgcgcgatctggtacacgctattccgctgtatgcgatcaaacaa
ggtctgctgaccgttgagaagaaaggcaagaaaaacatcttctctggtcgcattctggaa
attgaaggtctgccggatctgaaagttgagcaggcctttgagctgaccgatgcgtccgcc
gagcgttctgccgctggttgtactatcaagctgaacaaagaaccgatcatcgaatacctg
aactccaacatcgtcctgctgaagtggatgatcgcggaaggttacggcgatcgtcgtacc
ctggaacgtcgtattcagggcatggaaaaatggctggcgaatcctgagctgctggaagcc
gatgcagatgcggaatacgcggcagtgatcgacatcgatctggcggatattaaagagcca
atcctgtgtgctccgaacgatccggatgacgcacgtccgctgtctgcggtacagggtgag
aagatcgacgaagtgtttatcggttcctgcatgaccaacatcggtcacttccgtgctgcg
ggtaaactgctggatgcgcataaaggccagttgccgacccgcctgtgggtggcaccgcca
acccgtatggacgccgcgcagttgaccgaagaaggctactacagcgtcttcggtaagagc
ggtgcgcgtatcgagatccctggctgttccctgtgtatgggtaaccaggcgcgtgtagca
gacggtgcgacggtggtttccacctctacccgtaacttcccgaaccgtctgggtactggc
gcgaatgtcttcctggcttctgcggaactggctgctgttgcggcgctgattggcaaacta
ccgacgccggaagagtaccagacctacgtggcacaggtggataaaactgccgttgatact
taccgttacctgaacttcaaccagctttctcagtacaccgaaaaagcggacggggtgatt
ttccagactgcggtgtaa
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