Felis catus (domestic cat): 101080675
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Entry
101080675 CDS
T02385
Symbol
PLCG2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform X2
KO
K05859
phosphatidylinositol phospholipase C, gamma-2 [EC:
3.1.4.11
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca00562
Inositol phosphate metabolism
fca01100
Metabolic pathways
fca01521
EGFR tyrosine kinase inhibitor resistance
fca04012
ErbB signaling pathway
fca04014
Ras signaling pathway
fca04020
Calcium signaling pathway
fca04062
Chemokine signaling pathway
fca04064
NF-kappa B signaling pathway
fca04066
HIF-1 signaling pathway
fca04070
Phosphatidylinositol signaling system
fca04072
Phospholipase D signaling pathway
fca04360
Axon guidance
fca04370
VEGF signaling pathway
fca04380
Osteoclast differentiation
fca04611
Platelet activation
fca04613
Neutrophil extracellular trap formation
fca04625
C-type lectin receptor signaling pathway
fca04650
Natural killer cell mediated cytotoxicity
fca04662
B cell receptor signaling pathway
fca04664
Fc epsilon RI signaling pathway
fca04666
Fc gamma R-mediated phagocytosis
fca04670
Leukocyte transendothelial migration
fca04722
Neurotrophin signaling pathway
fca04750
Inflammatory mediator regulation of TRP channels
fca04919
Thyroid hormone signaling pathway
fca04933
AGE-RAGE signaling pathway in diabetic complications
fca04935
Growth hormone synthesis, secretion and action
fca05167
Kaposi sarcoma-associated herpesvirus infection
fca05169
Epstein-Barr virus infection
fca05170
Human immunodeficiency virus 1 infection
fca05171
Coronavirus disease - COVID-19
fca05200
Pathways in cancer
fca05205
Proteoglycans in cancer
fca05206
MicroRNAs in cancer
fca05214
Glioma
fca05223
Non-small cell lung cancer
fca05225
Hepatocellular carcinoma
Module
fca_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
101080675 (PLCG2)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
101080675 (PLCG2)
04014 Ras signaling pathway
101080675 (PLCG2)
04370 VEGF signaling pathway
101080675 (PLCG2)
04064 NF-kappa B signaling pathway
101080675 (PLCG2)
04066 HIF-1 signaling pathway
101080675 (PLCG2)
04020 Calcium signaling pathway
101080675 (PLCG2)
04070 Phosphatidylinositol signaling system
101080675 (PLCG2)
04072 Phospholipase D signaling pathway
101080675 (PLCG2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
101080675 (PLCG2)
04613 Neutrophil extracellular trap formation
101080675 (PLCG2)
04625 C-type lectin receptor signaling pathway
101080675 (PLCG2)
04650 Natural killer cell mediated cytotoxicity
101080675 (PLCG2)
04662 B cell receptor signaling pathway
101080675 (PLCG2)
04664 Fc epsilon RI signaling pathway
101080675 (PLCG2)
04666 Fc gamma R-mediated phagocytosis
101080675 (PLCG2)
04670 Leukocyte transendothelial migration
101080675 (PLCG2)
04062 Chemokine signaling pathway
101080675 (PLCG2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
101080675 (PLCG2)
04919 Thyroid hormone signaling pathway
101080675 (PLCG2)
09156 Nervous system
04722 Neurotrophin signaling pathway
101080675 (PLCG2)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
101080675 (PLCG2)
09158 Development and regeneration
04360 Axon guidance
101080675 (PLCG2)
04380 Osteoclast differentiation
101080675 (PLCG2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101080675 (PLCG2)
05206 MicroRNAs in cancer
101080675 (PLCG2)
05205 Proteoglycans in cancer
101080675 (PLCG2)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
101080675 (PLCG2)
05214 Glioma
101080675 (PLCG2)
05223 Non-small cell lung cancer
101080675 (PLCG2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
101080675 (PLCG2)
05171 Coronavirus disease - COVID-19
101080675 (PLCG2)
05167 Kaposi sarcoma-associated herpesvirus infection
101080675 (PLCG2)
05169 Epstein-Barr virus infection
101080675 (PLCG2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
101080675 (PLCG2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101080675 (PLCG2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
fca04131
]
101080675 (PLCG2)
Enzymes [BR:
fca01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
101080675 (PLCG2)
Membrane trafficking [BR:
fca04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
101080675 (PLCG2)
Endocytosis
Macropinocytosis
Phospholipase C
101080675 (PLCG2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
SH2
PI-PLC-Y
C2
SH3_1
PH
SH3_9
PH_12
PH_14
SH3_2
GDPD
EF-hand_like
Motif
Other DBs
NCBI-GeneID:
101080675
NCBI-ProteinID:
XP_019675679
EnsemblRapid:
ENSFCTG00005004998
UniProt:
M3W393
LinkDB
All DBs
Position
E2:55125124..55312759
Genome browser
AA seq
1265 aa
AA seq
DB search
MTAMVNMDTLPEYEKSQIKRTLELGTVMTVFSFRKSTPERRTVQVIMETRQVAWSKTADK
IEGFLDIMEIKEIRPGKNSKDFERAKAARQKEDCCFTILYGTQFVLSTLSLAADSKEDAT
KWLSGLKILHQEAMSASTPTIIESWLRKQIYSVDQTRRNSISLRELKTILPLVNFKVNSA
KFLKDKFVEIGAHKDELSFEQFHVFYKNLMFEQQKSILDEFKKDSSVFILGNTDRPDASA
VYLHDFQRFLLHEQQEVWAQDLNKVRERMTKFIDDTLRETAEPFLFVDEFLTYLFSRENS
IWDEKYDVVDIQDMNNPLSHYWISSSHNTYLTGDQLRSESSTEAYIRCLRMGCRCIELDC
WDGPDGKPIIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEHCCVEQQRHMARV
FKEVFGDLLLTKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNVEDKKDEHKQQGE
LYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTAEEELPQDIPPTELHFGEEWFHKKVEKR
TNAEKLLQEYCAETGGKDGTFLVRESKTFPNDYTLSFWRSGRVQHCRIRSVMEGGTMKYF
LTDNIMFTSIYDLIQHYRETHLRCAEFELRLTDPVPNPNPHESKPWYYDGLSRGEAEDML
MRVPRDGAFLIRRREGTDSYAITFRARGKVKHCRIHRDGRHFVLGTSAYFESLVELVSYY
EKHALYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRTVKALYDY
KAKRSDELSFCRGALIHNVSKEPWGWWKGDYGTRIQQYFPSNYVEDISTVDVEELEKQII
EDNPLGSLCRGILDLNTYNVVKAPQGKNQKAFVFILEPKKQGDPPVEFATDRVEELFEWF
QSIREITWKMDTKENNMKYWEKNQSIAIELSDLVVYCKPTSKTKDNLENPDFREIRSFVE
TKADSVVRQKPVDLLKYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTPDKY
MQMNQALFSLNGRTGYVLQPESMRTEKYDPMPPESQRKILMTLTVKVLGARHLPKLGRSI
ACPFVEVEICGAEYDNNKFKTTVVNDNGLSPVWAPTQEKVTFEIYDPNLAFLRFVVYEED
MFSDPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMQPVLESEEELYSSC
RQLRRRQEELNNQLFLYDTHQNLRNANRDALVKEFNVNENQLQLYQEKCNRRLREKRVSN
SRFYS
NT seq
3798 nt
NT seq
+upstream
nt +downstream
nt
atgaccgccatggtcaacatggacacccttcctgaatatgagaagagtcagatcaagaga
accctggagctgggcacggtgatgaccgtgttcagctttcgcaagtctaccccggagcgg
aggactgtccaggtgatcatggagacgcggcaggtggcctggagcaagacggctgacaag
attgaaggcttcttggatatcatggaaatcaaggaaatccgccccgggaagaactccaag
gattttgagcgcgcgaaggcagcccggcagaaggaggactgctgtttcaccatcttgtac
ggcacccagttcgtcctgagcactctcagtttggcagctgattctaaagaagacgcgact
aagtggctctctggcttgaaaatcttacaccaggaagcgatgagtgcgtctacgcccacc
attattgagagttggctgagaaagcagatttattcagtggatcaaaccagaagaaacagc
atcagcctccgagagctgaagaccatcttgcccctggtcaacttcaaagtgaacagtgcc
aagttcctcaaagataagtttgtggaaatcggcgctcacaaagatgaactcagctttgag
cagttccacgttttctataaaaatcttatgtttgagcagcaaaagtcgattcttgatgaa
ttcaaaaaagattcttctgtgttcatcttgggcaacaccgaccggccggatgcctccgct
gtttacctgcacgacttccagcggtttctcctacacgaacagcaggaggtttgggctcag
gatctgaacaaagtccgcgagcggatgacaaagtttatcgatgacaccctgagggagacc
gccgagcccttcctgtttgttgatgagttcctcacgtacctgttttcgcgggagaatagc
atctgggatgagaagtatgacgtcgtggacatacaggacatgaacaaccccttgtcccat
tactggatctcctcctcacataacacgtacctcaccggtgaccagctgcggagcgagtcg
tccacggaggcatacatccgctgcctgcgcatgggctgtcgctgcatcgagctggactgc
tgggacgggcccgatgggaagcccatcatctaccacggctggacgcggaccaccaagatc
aagtttgatgacgtcgtgcaggccatcaaagaccatgcctttgtcacctcaagcttcccg
gtgatcctgtccatcgaagagcactgctgtgtggagcagcagcgccacatggccagggtg
ttcaaggaggtgtttggcgacctgctgttgacgaagcccacggaggccagtgctgaccag
ctgccctcgcccagccagctgcgggagaagatcatcatcaagcataagaagctgggcccc
cgaggcgacgtggatgtcaacgtggaagataagaaagatgagcacaagcaacagggtgaa
ctgtacatgtgggattccattgaccagaaatggacccggcactactgtgccatcgctgat
gccaagctgtcgttcagcgatgacattgagcagactgcagaggaggagctgccccaggat
ataccccccacggagctgcattttggggaggagtggttccacaagaaggtggagaagaga
acaaacgccgagaagctgctgcaggaatactgtgccgagacggggggcaaagatgggacc
ttcttggtgcgggagagcaagaccttccccaacgactacaccctgtccttctggcggtcc
ggccgggtccagcactgccggatccgctccgtcatggagggcgggaccatgaagtacttc
ctgactgacaacatcatgttcaccagcatctatgacctcatccagcactaccgtgagacg
cacctgcgctgtgccgagttcgagctccggctcaccgaccccgtgcccaaccccaacccc
cacgagtcaaagccgtggtactatgatggcctgagccgcggggaagcagaggacatgctg
atgagagttccccgggacggggccttcctgatccggaggcgggaaggtaccgactcctac
gccatcaccttcagggccaggggcaaagtaaagcattgccgcatccatcgggacggccgg
cactttgtgctggggacctctgcctacttcgagagcctcgtcgagctggtcagttactac
gagaagcacgcgctgtaccggaagatgcggctgcgctatcctgtgacgcctgagctgctg
gagcgctacaatatggaacgagatatcaactccctctatgacgtcagcaggatgtatgtg
gatcccagtgaaatcaacccgtccatgcctcagaggaccgtcaaagctctgtatgactac
aaagccaagcgaagcgatgagctgagcttctgccgtggggccctcattcacaacgtctcc
aaggagccctggggctggtggaaaggagactatgggaccaggatccagcaatacttccca
tccaactatgttgaggacatttcaacggtcgatgtggaagaactggaaaagcagattatt
gaagacaatcccttagggtctctttgcagaggaatactggatctcaacacctataacgtc
gtgaaagccccgcaggggaaaaaccagaaggcgttcgtgttcatcctggagcccaagaag
caaggcgaccctccggtggagtttgccacagacagggtcgaggagctctttgagtggttt
cagagcatccgggagatcacctggaagatggacaccaaggagaacaacatgaagtactgg
gagaagaaccagtccatcgccatcgagctctcggacctggtagtctactgcaagcccacc
agcaagaccaaggacaatttagaaaaccccgacttccgagaaatccgctccttcgtggag
acgaaggctgacagtgtcgtcagacagaaaccggtcgacctcctcaagtacaatcagaag
ggcctgacccgtgtttacccgaagggacagagggtggactcctccaactacgaccccttt
cgcctctggctatgtggctcccagatggtggcactcaatttccagactccagacaagtac
atgcagatgaatcaagccttgttctcactcaacgggcggacaggctacgtcctgcagccc
gagagcatgaggacggagaagtacgaccccatgccgcccgaatcccagcggaagattctg
atgactctgaccgtcaaggttctcggggctcgccatctccccaaacttggccgaagcatc
gcatgtccctttgtggaggtggaaatctgcggggctgaatatgacaacaacaagtttaag
accacagttgtgaatgacaatggcctaagccccgtttgggctccgacacaggagaaggtg
acctttgaaatttatgacccaaacctcgcgtttctgcgctttgtggtctacgaggaagat
atgttcagtgatcctaacttcctcgctcatgccacttaccccatcaaaggaatcaaatca
ggattcagatctgttcctctgaagaacgggtacagtgaagatatcgagctggcttccctc
ctggtgttctgtgagatgcagccagtcctggagagtgaagaggaactctactcctcctgc
cgccagctgcgaaggcggcaggaagagctgaacaaccagctgttcctgtacgacacacac
cagaatctgcgcaatgccaaccgggatgccctcgtcaaagagttcaacgtcaacgagaac
cagctccagctgtaccaggagaagtgcaaccggaggttaagagagaagagagttagcaac
agtaggttttactcatag
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integrated database retrieval system
