Felis catus (domestic cat): 101080765
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Entry
101080765 CDS
T02385
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca00010
Glycolysis / Gluconeogenesis
fca00020
Citrate cycle (TCA cycle)
fca00620
Pyruvate metabolism
fca00785
Lipoic acid metabolism
fca01100
Metabolic pathways
fca01200
Carbon metabolism
fca01210
2-Oxocarboxylic acid metabolism
fca04066
HIF-1 signaling pathway
fca04922
Glucagon signaling pathway
fca05230
Central carbon metabolism in cancer
fca05415
Diabetic cardiomyopathy
Module
fca_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
101080765 (PDHA1)
00020 Citrate cycle (TCA cycle)
101080765 (PDHA1)
00620 Pyruvate metabolism
101080765 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
101080765 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
101080765 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
101080765 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
101080765 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
101080765 (PDHA1)
Enzymes [BR:
fca01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
101080765 (PDHA1)
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
101080765
NCBI-ProteinID:
XP_004001586
EnsemblRapid:
ENSFCTG00005001898
LinkDB
All DBs
Position
X:15590980..15607371
Genome browser
AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSGVAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSSDPPFEVRGANQWIKFKSIS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaaaatgctcgcagctgtctcccgcgtgttgtcgggcgtcgcccagaagccggca
agcagagtgctggtggcatcccgtaattttgcaaatgatgctacatttgaaattaagaaa
tgtgatcttcaccgactggaagagggccctcctgtcaccacggtactcaccagggaggat
gggctcaaatactataggatgatgcagactgttcgccgaatggaattaaaggcagatcag
ctgtataaacagaaaattattcgtggtttttgtcacttgtgtgatggtcaggaagcttgt
tgtgtgggcctggaggccggcataaatcccacagaccatcttatcacagcctatcgggct
catggcttcacctttactcgtggactttctgtccgagaaattcttgcagagcttacagga
cgaagaggaggttgcgctaaagggaaaggcggatcgatgcatatgtatgccaaaaacttc
tacgggggcaacggcatcgttggagctcaggtgcccctgggagcagggattgctctggcc
tgtaagtataacggaaaggatgaggtctgtttgactttatatggcgatggtgctgctaac
caaggtcagatattcgaagcttacaatatggcagctttgtggaaattgccatgtattttc
atctgtgaaaataaccgctatggaatgggaacatccgttgagagagcagcggccagcacg
gattactacaagagaggtgacttcattcctgggctgagggtagatggaatggatatcctg
tgtgtccgggaggcgacgaggtttgcagccgcctactgtagatctggaaaggggcccata
ctgatggagctacagacttaccgctaccacggacatagcatgagtgaccctggtgtcagt
taccgtacacgagaggagattcaggaagtaagaagtaagagtgaccctattatgcttctc
aaggatagaatggtgaacagcaacctggccagtgttgaggaattaaaggaaattgatgtt
gaagtgaggaaagagattgaggatgctgcccagtttgccaccgctgatcctgaaccgcct
ttggaagaactaggctatcacatttacagcagcgacccaccttttgaagttcggggtgca
aatcagtggatcaagtttaagtccatcagttaa
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