Felis catus (domestic cat): 101083046
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Entry
101083046 CDS
T02385
Symbol
ACACA
Name
(RefSeq) acetyl-CoA carboxylase 1 isoform X7
KO
K11262
acetyl-CoA carboxylase / biotin carboxylase 1 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca00061
Fatty acid biosynthesis
fca00620
Pyruvate metabolism
fca00640
Propanoate metabolism
fca01100
Metabolic pathways
fca01212
Fatty acid metabolism
fca04152
AMPK signaling pathway
fca04910
Insulin signaling pathway
fca04922
Glucagon signaling pathway
fca04936
Alcoholic liver disease
Module
fca_M00082
Fatty acid biosynthesis, initiation
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
101083046 (ACACA)
00640 Propanoate metabolism
101083046 (ACACA)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
101083046 (ACACA)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
101083046 (ACACA)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
101083046 (ACACA)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
101083046 (ACACA)
04922 Glucagon signaling pathway
101083046 (ACACA)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
101083046 (ACACA)
Enzymes [BR:
fca01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
101083046 (ACACA)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
101083046 (ACACA)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
101083046 (ACACA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
MetallophosN
Motif
Other DBs
NCBI-GeneID:
101083046
NCBI-ProteinID:
XP_006940177
EnsemblRapid:
ENSFCTG00005029204
LinkDB
All DBs
Position
E1:23856319..24136417
Genome browser
AA seq
2348 aa
AA seq
DB search
MDEPSPLAKPLELNQHSRFIIGSVSEDNSEDEISNLVKLDLLEEKEGSLSPASVGSDTLS
DLGISSLQDGLALHMRSSMSGLHLVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEK
VLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPG
GPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMWAL
GDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQELYQKGYVKDVDDGLKA
AEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEV
QILADQYGNAISLFGRDCSVQRRHQKIIEEAPAAIATPAVFEHMEQCAVKLAKMVGYVSA
GTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRMMY
GVSPWGDAPIDFENSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGY
FSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLET
ESFQLNRIDTGWLDRLIAEKVQAERPDTMLGVVCGALHVADVSLRNSISNFLHSLERGQV
LPAHTLLNTVDVELIYEGVKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDG
SSYTTYMKEEVDRYRITIGNKTCVFEKENDPSVMRSPSAGKLIQYIVEDGGHVFSGQCYA
EIEVMKMVMTLTAAESGCIHYVKRPGAALDPGCVIAKMQLDNPSKVQQAELHTGSLPRIQ
STALRGEKLHRVFHYVLDNLVNVMNGYCLPDPFFSSRVKDWVERLMKTLRDPSLPLLELQ
DIMTSVSGRIPPNVEKSIKKEMAQYASNITSVLCQFPSQQIANILDSHAATLNRKSEREV
FFMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLRVETQFQNGHYDKCVFALREENKSD
MNTVLNYIFSHAQVTKKNLLVTMLIDQLCGRDPTLTDELLNILTELTQLSKTTNAKVALR
ARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYH
SNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNRGNIPTLNRM
SFSSNLNHYGMTHVASVSDVLLDNSFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFCDSP
PQSPTFPEAGHTSLYDEDKLQVPRDEPIHILNVAIKTDCDIEDDRLAAMFREFTQQNKAT
LVEHGIRRLTFLVAQKDFRKQVNYEVDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALA
FQLELNRMRNFDLTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEAS
FEYLQNEGERLLLEAMDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMR
YGSRLWKLRVLQAELKINIRLTPTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMF
QAYGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMST
QAFLPSPPLPSDMLTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMTLKSPEYPEGRDII
VIGNDITYLIGSFGPQEDLLFLRASELARAEGIPRIFVAANSGARIGLAEEIRHMFHVAW
VDPEDPYKGYKYLYLTPQDYKRVSALNSVHCEHVEDEGESRYKITDIIGKEEGLGAENLR
GSGMIAGESSLAYNEIITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVL
GREVYTSNNQLGGIQIMHNNGVTHSIVCDDFEGVFTVLHWLSYMPKNVHSLVPLLNSKDP
IDRIIEFVPTKAPYDPRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARL
GGIPVGVVAVETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNREGL
PLMVFANWRGFSGGMKDMYDQVLKFGAYIVDSLRECSQPVLVYIPPQAELRGGSWVVIDP
TINPRHMEMYADRESRGSVLEPEGTVEIKFRRKDLVKTMRRVDPVYIRLAERLGTPELSA
AERKELENKLKEREEFLIPIYHQVAVQFADLHDTPGRMQEKGVINDILDWKTSRTFFYWR
LRRLLLEDLVKKKIHNANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLVEWLEKQL
TEEDGVRSVIEENIKYISRDYVLKQIRSLVQANPEVAMDSIVHMTQHISPTQRAEVVRIL
STMDSPST
NT seq
7047 nt
NT seq
+upstream
nt +downstream
nt
atggatgaaccatcccccttggccaaacctctggagctgaaccagcactctcggttcata
attggttctgtatctgaagataactcagaggatgaaatcagcaacctagtgaagctggac
ctactggaggagaaggaaggctctctgtcaccagcttctgttggctcagatacgctctct
gatttggggatttccagcctacaggatggcttggccttgcacatgaggtccagcatgtct
ggcttgcatctagtaaagcaaggtcgagaccgaaagaaaatagactcacagcgagatttc
actgtagcttcaccagcagaatttgttacgcgttttggggggaataaagtgattgagaag
gttcttattgccaacaatggcatcgcagcagtgaaatgcatgcggtccatccgccgatgg
tcttatgagatgtttcgaaatgaacgtgcaatccgatttgttgttatggtcacacctgaa
gacctgaaagccaatgcagaatacattaagatggcagatcactatgtgccggtgccagga
ggaccaaacaacaacaactatgcaaacgtggaattaattcttgatattgctaaaaggatc
ccagtacaagcagtgtgggctggctggggtcatgcttctgagaatcccaagctcccagaa
cttcttttgaaaaatggcatcgccttcatgggtcctccaagccaggccatgtgggctttg
ggggataagattgcatcttccatagtggctcaaactgctggtatcccaactcttccctgg
agtgggagtggtcttcgtgtggactggcaggaaaatgatttttcaaaacgtatcttaaat
gttccccaggaattatatcaaaaaggttatgtgaaggatgtggatgatgggctgaaggca
gcagaggaagttggatatccagtaatgatcaaggcctcagaaggaggaggagggaaagga
atcagaaaagttaacaatgcagatgacttccctaacctcttcagacaggttcaagctgaa
gtccctggatctcctatatttgtgatgagactagccaaacaatcccgtcatctggaggta
cagattttagcagatcagtatggcaatgctatctctctgtttggtcgtgactgctctgtg
cagcgcaggcatcagaagattattgaagaagcaccagctgctattgctactccagcagta
ttcgaacatatggaacagtgtgcggtgaaacttgccaaaatggttggttatgtgagtgca
gggactgtcgaatacctctacagccaggatggaagcttctactttctggaactgaaccct
cggctacaggtggagcacccttgtacagagatggtggctgatgtcaacctccctgcagcg
caactccagattgccatggggatccctctgtatagaatcaaggatattcgtatgatgtat
ggagtatctccctggggtgatgctcccattgattttgaaaattctgctcatgttccttgc
ccaaggggccatgttattgctgctcggatcactagtgaaaatccagatgagggttttaag
cccagctcaggaacagttcaggaactgaatttccgtagcaataagaatgtttggggttat
ttcagtgttgctgctgcagggggccttcacgaatttgctgattctcagtttggtcactgc
ttctcctggggagaaaacagagaggaagcaatttcaaacatggtggtggctttgaaggag
ctatctattcggggtgactttcgaactacagttgaatacctcatcaaattgctggagact
gagagttttcagctgaatagaattgacactggctggctagacagactgatagcagaaaaa
gtacaggcagagcgacctgataccatgttgggagttgtgtgtggggctctccacgtggca
gatgtgagcctacggaatagcatctctaacttccttcattccttagaaaggggtcaagtt
cttcctgctcatacgcttctgaatacagtagatgttgaacttatctatgagggagtcaaa
tatgtacttaaggtgactcgacagtcccccaactcgtatgtggtgatcatgaacggctca
tgcgtagaagtagatgtgcatcggctgagtgatggagggctgctcctgtcctatgatggc
agcagttataccacatacatgaaggaggaagtggatagatatcgtatcacaattggcaat
aagacctgtgtgtttgagaaggaaaatgacccttcagtgatgcgctcaccttctgctggg
aagttaatccagtatattgtggaggatggaggccatgtgttttctggccagtgctatgct
gagattgaggtgatgaagatggtaatgaccttaacagcagcagagtctggctgtatccat
tatgtcaaacggcctggagcagctcttgaccctggctgtgtgatagccaaaatgcagtta
gacaaccccagcaaggtccaacaggctgagcttcacacgggtagtctgccacggatccag
agcacagcactgagaggcgagaagctccatcgagtgttccattatgtcctggataatctg
gtcaacgtaatgaatggatactgccttccagatcctttttttagtagcagggtaaaagac
tgggtagagcggttgatgaagaccctcagagatccctccttgcctctcctagaattgcaa
gatatcatgaccagtgtctctggccgtattcccccgaatgtggagaagtctatcaagaag
gaaatggctcagtatgccagcaacatcacatcagtcctctgtcagtttcccagccagcag
attgccaacatcctagatagccatgcagctacattgaaccggaaatctgaacgggaagtt
ttcttcatgaacacccagagcattgtccagctggtacagaggtaccgaagtggcatccga
ggccacatgaaagctgttgtgatggatctgctacggcagtacctacgagtagagacacag
ttccagaatggtcactatgacaaatgtgtgtttgcccttcgagaagagaacaagagtgac
atgaacactgtgctaaactatatcttctctcatgctcaagtcaccaagaagaatcttctg
gtcacaatgcttattgatcagttgtgtggtcgggaccctactctcactgatgagctgctg
aatatcctcacagagctaactcaactcagtaagaccaccaatgccaaagtggcacttcga
gcacgccaggttcttattgcctcccatttgccatcatatgagcttcgccataaccaagta
gagtctatcttcctttcagctattgacatgtatggacatcagttttgcattgagaacctg
cagaaactcatcttgtctgaaacatctatttttgatgtcctaccaaacttcttctatcac
agcaaccaggtagtgaggatggcagctctggaggtttatgttcgaagggcttacattgcc
tatgaacttaacagcgtccaacatcgccagcttaaggacaatacctgcgtggtggaattc
cagttcatgctgcccacatcgcatccaaacagagggaacatccccacgctaaacagaatg
tccttctcctccaacctcaaccactatggcatgactcacgtagctagtgtcagcgatgtg
ctgttggacaactcattcactccaccgtgtcagcggatgggcggaatggtctcttttcgg
actttcgaagattttgtcaggatctttgatgaagtgatgggctgcttctgtgactcccca
ccccaaagccccacgttccctgaggcaggtcacacatctctgtatgatgaagacaagtta
caggtccccagggatgaaccaattcacattctgaatgtggctatcaagactgactgtgat
attgaggatgacagactggcagctatgttcagagagtttacccaacaaaataaagctacc
ctggttgagcatgggatacggcgccttactttcctggtcgcacaaaaggatttcagaaaa
caggtcaactatgaggtggatcagagatttcatagagaatttcctaaatttttcacgttt
cgagcaagggataagtttgaggaggatcgtatctatcgtcacctggagcctgccctagct
ttccagttagaactgaaccggatgagaaattttgaccttactgccattccatgtgctaat
cataagatgcacctgtatcttggggcagccaaggtggaagtgggcactgaagtgacagac
tataggttctttgttcgtgcaatcatcagacattctgatctggtcaccaaggaagcttct
tttgaatatctacaaaatgaaggggagcggctgctcctggaggccatggatgaattggaa
gttgcttttaataatacaaatgttcgcactgactgcaaccacatcttcctcaactttgtg
cccacagtcattatggacccatcaaagattgaggaatctgtgcggagcatggtaatgcgc
tatggaagtcggctgtggaaattacgtgtcctccaggcagaactgaaaatcaacattcgc
ctgacaccaactggaaaagcaattcccatccgcctcttcctgacaaatgagtccggctat
tacttggacatcagcttgtacaaggaagtgactgactccaggacagcacagatcatgttt
caggcatatggagacaaacagggaccattgcatggaatgttaatcaacactccatatgtc
accaaagacctacttcaatcaaagagattccaggcacaatccttggggacaacatacata
tatgatatcccagagatgtttcggcagtctctgatcaaactctgggagtctatgtccact
caagcattccttccatcaccccccctgccttctgacatgctaacgtatactgagcttgtg
ttggatgatcagggccagctggtccacatgaacaggcttccaggaggaaatgagattggc
atggtagcttggaaaatgacccttaaaagtcctgaatatccagaaggccgagatatcatt
gttattggcaatgacatcacatacctgattgggtcctttgggccccaggaggatttgctg
tttctcagagcttctgagcttgccagggcagagggtatcccacgcatctttgtcgcagcc
aacagcggagcacgaattggactggcagaggaaattcgtcatatgtttcacgtggcctgg
gtagatcctgaggatccttacaagggatacaaatacttatatctgacccctcaggattat
aagagggtcagtgctctcaactctgtccactgtgaacatgtagaagatgaaggagaatcc
aggtacaagataactgatattattgggaaggaagagggacttggagcagagaaccttcga
ggctctggaatgattgctggagaatcctcattggcctataatgagattatcaccatcagc
ttggttacatgccgggctattgggatcggagcttaccttgtccggctgggacagagaacc
atccaggttgaaaattctcacttaattctgaccggagctggagctctcaacaaagtcctt
gggcgggaagtatacacctccaataaccagcttgggggcatccagatcatgcacaacaat
ggggtgacccacagcatcgtttgtgatgactttgaaggggttttcactgtcctacactgg
ctgtcttacatgcctaagaatgtgcacagtttagtacctctcctgaactccaaggatccg
atagatagaatcatcgaatttgttcctacgaaggccccctatgatcctcgatggatgcta
gcaggccgtcctcacccaacccagaaaggtcagtggttgagtggattctttgactatgga
tctttctctgaaatcatgcaaccctgggcacagactgtggtggttggcagagccaggcta
ggaggaatacctgtaggagtagttgctgtagaaacccgaacagtggaactaagtatccca
gccgaccctgcaaacctggattctgaagccaagataatccagcaggctggccaggtttgg
tttccagattctgcgtttaagacctatcaggctatcaaggacttcaaccgtgaagggctg
cctctgatggtctttgccaactggagaggcttctccggtgggatgaaagatatgtacgac
caggtgctgaagtttggtgcttacatcgtggatagcttacgggagtgctcccagcctgtg
ctggtttacattcctcctcaagctgagctccggggtggctcctgggttgtgattgacccc
accatcaacccccggcacatggagatgtacgctgaccgagaaagcaggggatcagttctg
gagccagaagggacagtagaaatcaaattccgcagaaaagatctggtgaaaaccatgcgt
cgggtggacccagtctacattcgcttggctgaacgattgggcaccccagagctaagcgca
gctgagcggaaggagctggagaacaagttgaaggagcgggaggaattcctaattcccatt
taccatcaggtagccgtgcagtttgctgacttgcacgacacaccaggccggatgcaggag
aagggtgttattaacgacatcctggattggaaaacatcccgtaccttcttctactggcgg
ctgaggcgtctcctgctggaggacctggtcaaaaagaaaatccacaatgccaacccagag
ctcactgatggtcagatccaggccatgttaaggcgctggtttgtagaagtggaaggaacc
gtgaaggcctatgtttgggacaataacaaggatctagtggagtggctggagaaacagctg
accgaagaagatggtgttcgctcagtaatcgaggaaaacatcaaatacatcagcagagac
tatgtcctcaagcagatccgcagcttggtacaggccaatcccgaggttgccatggattcc
atcgtccatatgacccagcacatctcacccactcagcgagcagaagtcgtacggatcctc
tccacgatggactccccttcaacatag
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integrated database retrieval system
