Felis catus (domestic cat): 101100374
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Entry
101100374 CDS
T02385
Symbol
PDHB
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit beta, mitochondrial
KO
K00162
pyruvate dehydrogenase E1 component subunit beta [EC:
1.2.4.1
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca00010
Glycolysis / Gluconeogenesis
fca00020
Citrate cycle (TCA cycle)
fca00620
Pyruvate metabolism
fca00785
Lipoic acid metabolism
fca01100
Metabolic pathways
fca01200
Carbon metabolism
fca01210
2-Oxocarboxylic acid metabolism
fca04066
HIF-1 signaling pathway
fca04922
Glucagon signaling pathway
fca05230
Central carbon metabolism in cancer
fca05415
Diabetic cardiomyopathy
Module
fca_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
101100374 (PDHB)
00020 Citrate cycle (TCA cycle)
101100374 (PDHB)
00620 Pyruvate metabolism
101100374 (PDHB)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
101100374 (PDHB)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
101100374 (PDHB)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
101100374 (PDHB)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
101100374 (PDHB)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
101100374 (PDHB)
Enzymes [BR:
fca01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
101100374 (PDHB)
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Gene cluster
GFIT
Motif
Pfam:
Transket_pyr
Transketolase_C
Motif
Other DBs
NCBI-GeneID:
101100374
NCBI-ProteinID:
XP_003982424
EnsemblRapid:
ENSFCTG00005017717
UniProt:
M3VY34
LinkDB
All DBs
Position
A2:complement(26379521..26385308)
Genome browser
AA seq
359 aa
AA seq
DB search
MAAVSGLMRRPLEQVSGLLRRRFHRTAPAALQVTVREAINQGMDEELERDEKVFLLGEEV
AQYDGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAI
DQVINSAAKTYYMSGGFQSVPIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNS
EDAKGLIKSAIRDNNPVVVLENELMYGVPFEFPSEAQSKDFLIPIGKAKIERQGTHITVV
SHSRPVGHCLEAATVLSKEGIECEVINMRTIRPMDIETIEASVMKTNHLITVEGGWPQFG
VGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSVPQVKDIIFAIKKTLNI
NT seq
1080 nt
NT seq
+upstream
nt +downstream
nt
atggcggcggtgtctgggctgatgcggagaccccttgaacaggtctccgggctgctgagg
aggcgcttccaccgaacggcgccggcggcgctgcaggtgacagttcgtgaagctataaac
caaggtatggatgaggagctggaaagagatgagaaggtgtttctgcttggggaagaagtt
gcccagtatgatggggcatataaggttagtcgaggcctgtggaagaaatacggagataag
aggatcatagacactcccatatctgagatgggctttgctggaattgccgtgggtgcggcc
atggctgggttgaggcccatttgtgaatttatgaccttcaatttctctatgcaagccatt
gaccaggttataaactcagctgccaagacctactacatgtcagggggctttcagtctgtg
cccatagtcttcagggggcccaatggcgcctcagcaggcgtggctgcccagcactcacag
tgctttgctgcctggtatgggcactgcccaggcttaaaggtggtcagcccctggaattca
gaggatgcaaaaggacttattaaatcagccattcgggataacaacccagtggtggtgcta
gagaatgaactgatgtatggagttccttttgaatttccctcagaagctcaatcaaaagat
tttctgattcccattggaaaagccaaaatagaaaggcaagggacacacataactgtagtt
tcccattcaagacccgtgggccactgcttagaagctgcaacggtgctatccaaagaagga
attgaatgtgaggtgataaatatgcgaaccatcagaccaatggacattgaaacaatagaa
gccagtgtcatgaagaccaatcatctcataactgtggaaggaggctggccacagtttgga
gtaggagctgaaatttgtgccaggatcatggaaggccctgcattcaatttcctggatgct
cctgcagttcgtgtcactggtgctgatgtccctatgccttatgcaaagattctagaagac
aactcggtacctcaggttaaagacatcatatttgcaataaagaaaacattaaatatctag
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