KEGG   Candidatus Filomicrobium marinum W: BN1229_v1_0321
Entry
BN1229_v1_0321    CDS       T03856                                 
Name
(GenBank) Pyrroline-5-carboxylate dehydrogenase
  KO
K13821  RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]
Organism
fil  Candidatus Filomicrobium marinum W
Pathway
fil00250  Alanine, aspartate and glutamate metabolism
fil00330  Arginine and proline metabolism
fil01100  Metabolic pathways
fil01110  Biosynthesis of secondary metabolites
Module
fil_M00970  Proline degradation, proline => glutamate
Brite
KEGG Orthology (KO) [BR:fil00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    BN1229_v1_0321
   00330 Arginine and proline metabolism
    BN1229_v1_0321
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:fil03000]
    BN1229_v1_0321
Enzymes [BR:fil01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.88  L-glutamate gamma-semialdehyde dehydrogenase
     BN1229_v1_0321
  1.5  Acting on the CH-NH group of donors
   1.5.5  With a quinone or similar compound as acceptor
    1.5.5.2  proline dehydrogenase
     BN1229_v1_0321
Transcription factors [BR:fil03000]
 Prokaryotic type
  Ribbon-helix-helix
   Other families
    BN1229_v1_0321
SSDB
Motif
Pfam: Aldedh Pro_dh Pro_dh-DNA_bdg PRODH
Other DBs
NCBI-ProteinID: CFX00979
UniProt: A0A0D6JB27
LinkDB
Position
1:313791..317003
AA seq 1070 aa
MAVMDSPLAIGGPTISALDLTTPDKDLAAAHLADEQRLVAELLAESELHDGERRRVSEVA
RQLVHCARANRHKFGGVDAFMREYGLSSEEGAILMCVAESLLRIPDHETQDQLIAEKIGE
GAWDKHLGHSDSMFVNASTWGLMLTGRVVKLRDAKGASPISVLKRLVGRSGEPVIRQAIR
RSVSILGDQFVLGRTIKDALARAQPLQERGYMFSYDMLGEAARTQADADRYFDRYMSALD
AIAATTGPVMTQHPDTLMRRPSLSVKLSALHPRYEPGKEARLDDELLPKLMRLFTEARKQ
GISVTIDAEEQDRLELQLRMFGRAYEDPALHGWHGLGLAVQAYSKRMMPQLRWLRRLAER
GGQRIPVRLVKGAYWDSEIKRAQELGLRDYPVFTRKLHTDLSFISGVRFLLSDRKAFYPQ
FATHNAQSLAAVYVAAANTPFEFQRLHGMGEALYEEVVGDSRLGSVCRIYAPVGGHEDLL
PYLVRRLLENGANTSFVNRLADEDAPIAEIVRDPVAVLQSERDGTGPAQPNPIPRPRDIF
EPHRRASAGLALADRTVRSELLSGMASALLSPFEVGPLIDGELTLGDARPHRMVCPHDHR
QDIGQVHWSDAHHIEAAISSACRNAEAWDLTPVDERARILERAANLFESQRTQLMAVIVR
EAGKTVTAAHDDVREAVDFLRYYANEARRLFSGPISLPGPTGERNEMTYRARGPFACISP
WNFPIAIFTGQIAAALAAGNPVLAKPAEQTPLTAFLATRLLHQAGVPAGVLHLLPGYGTT
GAALVRDPRVQGIAFTGSNAAAWAIQKGLADRRAAIVPLIAETGGLNAMIADSSALPEQV
VRDVMRSAFDSAGQRCSAARMLFVHEDIALRTLSMLAGAIEELSLGDPMDYATDIGPVID
EQAQDTLDAHKLHLGREAQLIADGGMPEDCRAGTYVSPAAYEIERIDILKSEVFGPILYV
GRYQGGMLDKVIDAINATGYGLTLGLHSRINSVADHVARRAKVGNLYVNRNQIGALVGAQ
PFGGEGLSGTGPKAGGPNYVQRFATERVRSTDITATGGNLDLLRAGNGEA
NT seq 3213 nt   +upstreamnt  +downstreamnt
gtggcggttatggatagtccgcttgctatcggcgggccgacgatttcggctctcgatctt
acaacgcccgataaggatcttgcagctgcacatttagctgacgagcagcggcttgtcgcg
gaattgctagcggaaagcgaactgcacgacggcgagcgtcggcgcgtgagtgaggttgcg
cgtcaactcgtgcattgcgcgcgcgccaatcggcataaatttggcggcgtcgacgcgttt
atgagggaatacgggctttccagcgaggaaggcgcgatcctgatgtgcgtggcggagtcg
ctgttgcgtattcctgaccatgagacgcaggatcaattgatcgccgaaaaaattggtgaa
ggcgcttgggacaaacatctcggtcattccgacagcatgtttgtcaacgcttccacctgg
gggctgatgctcacgggccgtgtcgtaaaattgcgcgatgctaagggcgcgagcccgatc
agtgtgttgaagcggctggtcgggcgttctggcgagcccgttatccgacaggcaatccgg
cgttctgtctccatccttggagatcagttcgtgcttgggcggactattaaagatgcccta
gcgcgtgctcagccgctgcaagagcgtggctacatgttctcctacgatatgctgggggaa
gccgcgcgcacgcaggccgacgcagaccgctatttcgacagatatatgtccgctctggat
gcgatcgcggcgacaaccgggccagtgatgacgcagcatcctgacacgttgatgcgccgc
ccgagcttatcggtgaagctgtctgcgctgcatccgcgttatgagcccggcaaagaggcg
cgccttgacgatgagttgttaccgaagctgatgaggttgttcacggaggcgcgtaagcag
ggcatttccgtgacgattgacgctgaggagcaagatcgtctcgaacttcagctgcgcatg
tttggtcgcgcctatgaggacccggcgctgcatgggtggcatggtcttggtcttgccgtt
caggcgtattctaagcgcatgatgcctcagttgcgatggctgagacgtcttgctgaacgg
ggcggtcagcgcattccggtgcggctggtgaaaggggcttattgggacagcgaaatcaag
cgggctcaggagttgggcttgcgggactacccggtattcactcgcaagctgcataccgac
ctttcgtttatctccggcgtccgcttcctcctgtctgatcgcaaggcgttctacccgcag
tttgcgacgcataacgcgcaatcccttgccgccgtttacgtggcggcggcgaacacgccg
tttgaatttcagcggctgcatggcatgggagaggcgctttatgaggaagtggtgggcgat
agtcggcttggctcggtctgccggatctatgcgcctgttggcggccacgaagatttgttg
ccgtatcttgtgcgccggcttctcgaaaacggggctaatacgtcgttcgtcaaccgttta
gcggacgaagatgcaccaatcgctgagatcgttcgtgatccggttgcggttttgcaaagt
gagcgcgatggaacgggacctgctcagcctaaccccattccgcgtccgcgcgacattttc
gaaccgcatcgccgtgcaagtgccgggctcgccctggctgatcgcacggtacgaagtgaa
ctgctttcgggcatggcgagtgctcttctctcgcctttcgaagttggaccgttgatcgac
ggtgagctgacacttggtgatgccagacctcatcgtatggtttgcccgcatgatcaccgc
caggatatcggccaggttcactggagtgatgctcaccatatcgaagcggctatttcgagt
gcctgccggaatgcggaggcatgggaccttacacctgtggacgagcgcgcgcgcattcta
gagcgtgcggccaacttgttcgaaagccagcgtacgcagttgatggcggtcattgtccgc
gaggctggaaaaacagtcactgcagcgcatgatgacgtccgcgaagccgttgatttcctg
cggtactacgccaacgaggcgagacgacttttcagcggaccgatttcgcttcccggacct
accggcgagcgcaatgaaatgacgtatcgggcgcggggtccctttgcctgtatcagtccc
tggaacttcccgatcgcaatctttacggggcaaatcgcggcggcgctggcggcaggaaat
cctgttcttgcaaaaccggcagaacaaactcctctgacggcgtttctggcaacacggttg
ttgcatcaagccggtgtgcctgccggtgtgctgcatctgctgccagggtatggcacgacc
ggtgcggcattggtccgtgatccgcgtgttcagggtatcgcctttacggggtccaatgcg
gcagcctgggccattcagaagggacttgctgacaggcgtgcggcgattgttccgctgatt
gcggaaaccggcgggctgaacgcaatgatcgctgactctagcgcgttacccgaacaggtt
gttcgggatgttatgcgatcggcgtttgacagtgccggacagcgttgttctgcggcccgc
atgttgttcgttcacgaagacattgcgctgcgcacactcagcatgctcgcgggggccatc
gaggaacttagtttaggggacccgatggactatgcgacggatatcggaccggttattgac
gagcaggctcaagatacgctggacgcgcataagctgcatttgggccgtgaggctcagttg
attgccgatggaggtatgccggaggactgcagggcggggacgtacgtcagcccggcagct
tatgagatcgagcggattgacattctcaagagcgaagtttttgggcccattctttatgtc
ggccgttatcaggggggcatgctggataaggtgatcgacgcgatcaatgccactgggtac
ggcctgacgttggggttacacagccggatcaattccgtcgctgaccatgttgcccggcgg
gcgaaggtcgggaatctctacgttaaccgcaaccagattggcgcgctcgtcggtgctcag
ccgtttggtggtgagggcttgtcagggacggggccgaaggctggtggtccaaattacgtg
caacggtttgcgactgaaagagttcgctccacagatatcaccgcgactgggggtaatctc
gaccttttacgcgctggaaacggagaagcctaa

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