Gracilinanus agilis (agile gracile opossum): 123242405
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Entry
123242405 CDS
T07702
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
gas
Gracilinanus agilis (agile gracile opossum)
Pathway
gas00010
Glycolysis / Gluconeogenesis
gas00020
Citrate cycle (TCA cycle)
gas00620
Pyruvate metabolism
gas00785
Lipoic acid metabolism
gas01100
Metabolic pathways
gas01200
Carbon metabolism
gas01210
2-Oxocarboxylic acid metabolism
gas04066
HIF-1 signaling pathway
gas04922
Glucagon signaling pathway
gas05230
Central carbon metabolism in cancer
gas05415
Diabetic cardiomyopathy
Module
gas_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
gas00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
123242405 (PDHA1)
00020 Citrate cycle (TCA cycle)
123242405 (PDHA1)
00620 Pyruvate metabolism
123242405 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
123242405 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
123242405 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
123242405 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
123242405 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
123242405 (PDHA1)
Enzymes [BR:
gas01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
123242405 (PDHA1)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
123242405
NCBI-ProteinID:
XP_044526068
LinkDB
All DBs
Position
3:374052533..374080573
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AA seq
395 aa
AA seq
DB search
MRKMLAVVSRVLTAVSPKPGAASETGRVLLATRNFANDASFDIKKCDIHRLEEGPPTTTI
LTREEGLKYYKIMQTVRRMELKADQLYKQKIIRGFCHLYDGQEACCVGLEAGINPSDHVI
TAYRAHGFTYTRGLTVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGA
GIALACKYNGKDEICLTLYGDGAANQGQIFETYNMAALWKLPCIFICENNRYGMGTSVER
AAASTDYYKRGDYIPGIRVDGMDVLCVREATKFAAAYCRSGKGPMVMELQTYRYHGHSMS
DPGVSYRTREEIQEVRSKSDPIMLLKDRMVNNNLASIEELKEIDVEVRKEIEDAAQFATA
DPEPPLEELGYHIYSREPPFEVRGANQWIKYKSIS
NT seq
1188 nt
NT seq
+upstream
nt +downstream
nt
atgaggaaaatgctcgccgtcgtttcccgcgtgctgacagccgtctccccgaaaccggga
gctgctagtgagactggaagagtgctattggcaacccgtaactttgcaaatgatgcttcg
tttgatattaagaaatgtgacattcatcgccttgaggagggccctcccaccacaacgatt
cttactagagaggaaggactcaagtactataagataatgcagactgtccgtcggatggaa
ttgaaagcagaccagctgtataagcaaaagatcatccgtggtttctgccacttgtatgat
ggtcaggaagcttgttgtgtggggcttgaggctggtataaatccttcagatcatgtgatt
acagcctatcgagctcatggctttacttatactcgtggacttactgttcgagaaattctg
gcagagcttacaggacgaagagggggctgtgctaaaggaaagggaggatcgatgcacatg
tatgccaagaacttctacgggggcaatggcattgttggagctcaggtacctctaggagct
ggtattgccctggcctgtaagtacaatggaaaagatgagatttgtttgactttgtatgga
gatggtgctgctaatcagggtcagatatttgaaacttacaatatggcagctttgtggaaa
ttgccttgtattttcatttgtgagaataatcgatatggaatgggaacttctgtagagaga
gcagcagccagcactgactactacaaaagaggagactatattccaggaataagggtagat
ggtatggatgtcttgtgtgtccgtgaggcaacaaaatttgcggctgcctactgcagatca
ggaaagggccccatggtgatggaactacagacatatcgttatcatggacacagcatgagt
gaccctggtgtcagttatcgtactcgggaagaaattcaggaagtgaggagtaagagtgac
cctatcatgcttctcaaggataggatggtgaacaacaaccttgccagtattgaagaatta
aaggaaattgatgtggaagtaaggaaagaaattgaagatgccgcccagtttgctaccgct
gatccagagccacctttggaagaattaggctatcatatctactccagagagccacctttt
gaagttcgtggtgcaaatcagtggatcaagtacaaatctatcagctaa
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