Gorilla gorilla gorilla (western lowland gorilla): 101147526
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Entry
101147526 CDS
T02442
Symbol
PTEN
Name
(RefSeq) phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1
KO
K01110
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:
3.1.3.16
3.1.3.48
3.1.3.67
]
Organism
ggo
Gorilla gorilla gorilla (western lowland gorilla)
Pathway
ggo00562
Inositol phosphate metabolism
ggo01100
Metabolic pathways
ggo01521
EGFR tyrosine kinase inhibitor resistance
ggo04068
FoxO signaling pathway
ggo04070
Phosphatidylinositol signaling system
ggo04071
Sphingolipid signaling pathway
ggo04115
p53 signaling pathway
ggo04140
Autophagy - animal
ggo04150
mTOR signaling pathway
ggo04151
PI3K-Akt signaling pathway
ggo04218
Cellular senescence
ggo04510
Focal adhesion
ggo04931
Insulin resistance
ggo05165
Human papillomavirus infection
ggo05166
Human T-cell leukemia virus 1 infection
ggo05200
Pathways in cancer
ggo05206
MicroRNAs in cancer
ggo05208
Chemical carcinogenesis - reactive oxygen species
ggo05213
Endometrial cancer
ggo05214
Glioma
ggo05215
Prostate cancer
ggo05218
Melanoma
ggo05222
Small cell lung cancer
ggo05224
Breast cancer
ggo05225
Hepatocellular carcinoma
ggo05230
Central carbon metabolism in cancer
ggo05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
ggo05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
ggo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
101147526 (PTEN)
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
101147526 (PTEN)
04070 Phosphatidylinositol signaling system
101147526 (PTEN)
04071 Sphingolipid signaling pathway
101147526 (PTEN)
04151 PI3K-Akt signaling pathway
101147526 (PTEN)
04150 mTOR signaling pathway
101147526 (PTEN)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
101147526 (PTEN)
09143 Cell growth and death
04115 p53 signaling pathway
101147526 (PTEN)
04218 Cellular senescence
101147526 (PTEN)
09144 Cellular community - eukaryotes
04510 Focal adhesion
101147526 (PTEN)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101147526 (PTEN)
05206 MicroRNAs in cancer
101147526 (PTEN)
05208 Chemical carcinogenesis - reactive oxygen species
101147526 (PTEN)
05230 Central carbon metabolism in cancer
101147526 (PTEN)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
101147526 (PTEN)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
101147526 (PTEN)
05214 Glioma
101147526 (PTEN)
05218 Melanoma
101147526 (PTEN)
05215 Prostate cancer
101147526 (PTEN)
05213 Endometrial cancer
101147526 (PTEN)
05224 Breast cancer
101147526 (PTEN)
05222 Small cell lung cancer
101147526 (PTEN)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
101147526 (PTEN)
05165 Human papillomavirus infection
101147526 (PTEN)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
101147526 (PTEN)
09167 Endocrine and metabolic disease
04931 Insulin resistance
101147526 (PTEN)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101147526 (PTEN)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
ggo01009
]
101147526 (PTEN)
Enzymes [BR:
ggo01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.16 protein-serine/threonine phosphatase
101147526 (PTEN)
3.1.3.48 protein-tyrosine-phosphatase
101147526 (PTEN)
3.1.3.67 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
101147526 (PTEN)
Protein phosphatases and associated proteins [BR:
ggo01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Dual specificity phosphatases)
Phosphatase and Tensin homologs (PTEN)
101147526 (PTEN)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PTEN_C2
DSPc
Y_phosphatase
PTPlike_phytase
Y_phosphatase3
DUF3256
Motif
Other DBs
NCBI-GeneID:
101147526
NCBI-ProteinID:
XP_018890663
Ensembl:
ENSGGOG00000000893
LinkDB
All DBs
Position
10:83202794..83310839
Genome browser
AA seq
388 aa
AA seq
DB search
MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVSCAERH
YDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMI
CAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNHLDYRPVALLF
HKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMYFEFPQPLPVCGDIKV
EFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICSIERADNDKEY
LVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPD
HYRYSDTTDSDPENEPFDEDQHTQITKV
NT seq
1167 nt
NT seq
+upstream
nt +downstream
nt
atgacagccatcatcaaagagatcgttagcagaaacaaaaggagatatcaagaggatgga
ttcgacttagacttgacctatatttatccaaacattattgctatgggatttcctgcagaa
agacttgaaggcgtatacaggaacaatattgatgatgtagtaagttgtgctgaaagacat
tatgacaccgccaaatttaattgcagagttgcacaatatccttttgaagaccataaccca
ccacagctagaacttatcaaacccttttgtgaagatcttgaccaatggctaagtgaagat
gacaatcatgttgcagcaattcactgtaaagctggaaagggacgaactggtgtaatgatt
tgtgcatatttattacatcggggcaaatttttaaaggcacaagaggccctagatttctat
ggggaagtaaggaccagagacaaaaagggagtaactattcccagtcagaggcgctatgtg
tattattatagctacctgttaaagaatcatctggattatagaccagtggcactgttgttt
cacaagatgatgtttgaaactattccaatgttcagtggcggaacttgcaatcctcagttt
gtggtctgccagctaaaggtgaagatatattcctccaattcaggacccacacgacgggaa
gacaagttcatgtactttgagttccctcagccgttacctgtgtgtggtgatatcaaagta
gagttcttccacaaacagaacaagatgctaaaaaaggacaaaatgtttcacttttgggta
aatacattcttcataccaggaccagaggaaacctcagaaaaagtagaaaatggaagtcta
tgtgatcaagaaatcgatagcatttgcagtatagagcgtgcagataatgacaaggaatat
ctagtactcactttaacaaaaaatgatcttgacaaagcaaataaagacaaagccaaccga
tacttttctccaaattttaaggtgaagctgtacttcacaaaaacagtagaggagccgtca
aatccagaggctagcagttcaacttctgtaacaccagatgttagtgacaatgaacctgat
cattatagatattctgacaccactgactctgatccagagaatgaaccttttgatgaagat
cagcatacacaaattacaaaagtctga
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