Gorilla gorilla gorilla (western lowland gorilla): 101154382
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Entry
101154382 CDS
T02442
Symbol
TPO
Name
(RefSeq) thyroid peroxidase
KO
K00431
thyroid peroxidase [EC:
1.11.1.8
]
Organism
ggo
Gorilla gorilla gorilla (western lowland gorilla)
Pathway
ggo00350
Tyrosine metabolism
ggo01100
Metabolic pathways
ggo04918
Thyroid hormone synthesis
ggo05320
Autoimmune thyroid disease
Module
ggo_M00043
Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine
Brite
KEGG Orthology (KO) [BR:
ggo00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
101154382 (TPO)
09150 Organismal Systems
09152 Endocrine system
04918 Thyroid hormone synthesis
101154382 (TPO)
09160 Human Diseases
09163 Immune disease
05320 Autoimmune thyroid disease
101154382 (TPO)
Enzymes [BR:
ggo01000
]
1. Oxidoreductases
1.11 Acting on a peroxide as acceptor
1.11.1 Peroxidases
1.11.1.8 iodide peroxidase
101154382 (TPO)
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Motif
Pfam:
An_peroxidase
Motif
Other DBs
NCBI-GeneID:
101154382
NCBI-ProteinID:
XP_030863120
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Position
2A:17526135..17672213
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AA seq
783 aa
AA seq
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MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR
NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS
EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV
YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD
IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQLPEEARPAAGTACLPFYRSSAACGTGD
QGALFGNLSTANPRQQMNGLTSFLDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSG
RAYLPFAPPRAPAACAPEPGIPGETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAA
LKALNAHWSADAVYQEARKVVGALHQVRGVVLGALGGCRQSGGRLVWVRSIVASLSQPAG
DYPTKTQQPQPPNNGSQTTQVSRPCGGLGIVSAVLAGSLQGSARQSCSKGGTGALSEEAQ
GLCVAPAAPGHHAPLPLSGLHCTGVQAPKLASSLTDTLSPGEVLSVPMLRVTGRCQQDPA
CLFLRGGLDEASGSGRDPGWGTRQLQHVLLLTSTLQTGPGLPLTVWDTEGLCRPRGRKER
EEREVLAGLNTAAWAQPLLMQARTAETCQKGGVSFLGWLCEAAFLQLPRGGTGVPGLDAL
QGGDILQLLYQEPHDQGGKVGAFQVRRDQNLPNSTGNRPACPLVADERLLGTQPRGSGRY
LLK
NT seq
2352 nt
NT seq
+upstream
nt +downstream
nt
atgagagcactcgctgtgctgtctgtcacgctggttatggcctgcacagaagccttcttc
cccttcatctcgagagggaaagaactcctttggggaaagcctgaggagtctcgtgtctct
agcgtcttggaggaaagcaagcgcctggtggacaccgccatgtacgccacgatgcagaga
aacctcaaaaaaagaggaatcctttctccagctcagcttctgtctttttccaaacttcct
gagccaacaagtggagtgattgcccgagcagcagagataatggaaacatcaatacaagcg
atgaaaagaaaagtcaacctgaaaactcagcaatcacagcatccaaccgatgctttatca
gaagatctgctgagcatcattgcaaacatgtccggatgtctcccttacatgctgcccccc
aaatgcccaaacacttgcctggcgaacaaatacaggcccatcacaggagcttgcaacaac
agagaccaccccagatggggcgcctccaacacggccctggcacgatggctccctccagtc
tatgaggacggcttcagtcagccccgaggctggaaccccggcttcttgtacaacgggttc
ccactgcccccggtccgggaggtgacaagacatgtcattcaagtttcaaatgaggttgtc
acagatgatgaccgctattctgacctcctgatggcatggggacaatacatcgaccacgac
atcgcgttcacaccacagagcaccagcaaagctgccttcgggggaggggctgactgccag
atgacttgtgagaaccaaaacccatgttttcccatacaactcccggaggaggcccggccg
gccgcgggcaccgcctgtctgcccttctaccgctcttcggccgcctgcggcaccggggac
caaggcgcgctctttgggaacctgtccacggccaacccgcggcagcagatgaacgggttg
acctcgttcctggacgcgtccaccgtgtatggcagctccccggccctagagaggcagctg
cggaactggaccagtgccgaagggctgctccgcgtccacgcgcgcctccgggactccggc
cgcgcctacctgcccttcgcgccgccacgcgcgcctgcggcctgtgcgcccgagcccggc
atccccggagagacccgcgggccctgcttcctggccggagacggccgcgccagcgaggtc
ccctccctgacggcactgcacacgctgtggctgcgcgagcacaaccgcctggccgcggcg
ctcaaggccctcaatgcgcactggagcgcagacgccgtgtaccaggaggcgcgcaaggtc
gtgggcgctctgcaccaggtgcgcggggtggtcctgggcgccctgggtggctgccggcaa
agcggggggcgcctcgtgtgggtgcgcagcatcgtggcttctctctcccagccagctggt
gattatcccaccaagacccaacaaccacagccccccaacaatggcagccagaccacccag
gtttcccggccctgtggtggcctgggcatcgtgtctgcagtcctagccgggagcctgcag
ggaagtgcgcgtcagtcctgttctaaaggaggcactggagccttgtccgaggaggcacag
gggctgtgtgtggcaccggctgcccccgggcaccatgcgcccctgccgctttctggcctt
cactgcactggggtccaggccccaaagctggcatccagcctcacagacaccctcagccca
ggtgaggtcctcagtgtccccatgctgagagtcacagggagatgccagcaggacccggcc
tgcctcttcctcaggggaggcctggacgaggcttctgggtcaggacgtgaccctggatgg
ggcaccaggcagctgcaacatgttctcctgctgacctccaccctgcagacgggcccgggt
ctccccctgactgtgtgggacacagaggggctctgccgaccccggggaaggaaagaacgg
gaggaacgtgaagtgctcgcaggactcaacacagccgcctgggcccagcctcttctcatg
caggccaggacagctgagacatgccagaaaggcggtgtttcattcctgggctggctctgc
gaggctgccttcttgcagcttccaagaggaggcacgggggttcccgggctggatgccctg
cagggaggggacatccttcagctactctaccaggagccacatgatcagggcggaaaagtc
ggggccttccaagtacgcagggaccagaatctcccaaattccactggaaacaggccagcg
tgcccgttggtcgcagacgagaggctcctggggacacagcctcgaggaagtggcagatac
ctcctcaagtaa
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