Geotrypetes seraphini (Gaboon caecilian): 117366095
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Entry
117366095 CDS
T09159
Symbol
JAK3
Name
(RefSeq) tyrosine-protein kinase JAK3 isoform X1
KO
K11218
Janus kinase 3 [EC:
2.7.10.2
]
Organism
gsh
Geotrypetes seraphini (Gaboon caecilian)
Pathway
gsh04217
Necroptosis
Brite
KEGG Orthology (KO) [BR:
gsh00001
]
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
117366095 (JAK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
gsh01001
]
117366095 (JAK3)
Enzymes [BR:
gsh01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
117366095 (JAK3)
Protein kinases [BR:
gsh01001
]
Non-receptor tyrosine kinases
JAK family [OT]
117366095 (JAK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
Jak1_Phl
SH2
Haspin_kinase
RIO1
FERM_M
Chalcone
ABC1
Motif
Other DBs
NCBI-GeneID:
117366095
NCBI-ProteinID:
XP_033813104
UniProt:
A0A6P8S512
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Position
8:119719860..119858524
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AA seq
1111 aa
AA seq
DB search
MAPLGDKTPLIRGEKSCRSSSLEAGALQVYLYFSNSQVLSSDFSLALSCGEYSAEELCVL
AAQACGILPVYHPLFALATEDLSSWFSPKHIFIVDESVPLVVVYRIRFFFPNWFGLESQK
SYRHSLQKDRPGAVLDCAVIDYLFAQCRSDFVTGQMNTALSLKVQQECLALAVLDMLRIK
QETGYSLPKLFSNISYKSCVPKSLQYQIQQHSFLTRRRIRQRVQRSLLRISTCNAQIQHL
KIKYLLDLEKLEPNFGMEMFPVQTPSAGRAHGTEKVIRVCGGSGIYWRLKDSEIWQVFCD
FPEITDIGITQAYYEKRPVESRIVTITKQDNKVLEAEFLGQKEALSFVSLVDGYYRLTVD
TYHYFCGNVAPPRLLWSIENQCHGPITSEFAVNKLKKLGSTGGQYILRCSPQHFNRYILT
ICTETPLGRDYKDCLITKTDSGYSLLGVTRHFYSLKELLEYYQSATLHAKKVTIQLQSCY
PPMPKEKSNLLIMRGSCPQPQTSPTKCRRNISQMTFQNIRPETIIWGESLGQGSFTKIFR
GIKRDIDNEESYETDVLLKVLDITYRNFNESFLEAASVMSLISHKHLVLLHGICVGTDSI
MVQEYVKLGPLDIYLKKQKDGSRITARWKLEVAKQLAYTLSFLRDKNIIHGNVSTKNILL
SREGDSSTGSPPFIKLSDSGVSITVMTKELLTDRIPWVAPECVRDPRSLVQESDCWSFGA
TLWEIFNGGSIPLSVLEPTAKVKFYQDQLQLPILKWTELANLINCCMNYRPFLRPSFRAI
IRDLNNLITSDYELLVDLSTGDLPVKDNFWRCMSLTDLQDPPFYEERHLKYISALGKGNF
GSVDLCRYDPLGDNTGDLVAVKKLQQSTAEHLRDFERETEILRSLHNDFIVQYRGVCYSA
GRKNLRLIMEYLPNGCLREYLQNHRDYLCQGKLLLYARQICKGMQYLGEKRYVHRDLATR
NILVENSNHVKIGDFGLAKILPQDKEYYVVHERGESPIFWYAPESLADSIFSRHSDSWSF
GVLLYELFTYGEKSSSPPSEFLQLIGSGNQLQLVNQLLKLLTGGIRLPEPPECPAEVHGL
MLQCWALQPAERPTFSDLEQRMEKYKQKIDP
NT seq
3336 nt
NT seq
+upstream
nt +downstream
nt
atggcgccactgggagacaaaacacctttgataaggggcgaaaagtcatgcagatcttcc
tccttggaagcaggtgccttgcaggtatacctgtacttcagcaactctcaagtgctctcc
tctgatttctctctggccttgtcctgtggagagtactcagccgaggagctgtgtgtactg
gctgcccaagcctgtggaattctgccggtgtatcatcccctctttgctctagcaacagaa
gacctgtcatcttggttttctccaaaacatattttcatagttgatgaatctgtgcctcta
gttgtggtctacagaattaggtttttttttcctaactggtttggactggagagccagaaa
tcctaccgtcatagcctgcagaaagataggcctggtgccgtcctggactgtgctgttatc
gattacctctttgcacagtgccgcagtgactttgtgactggacagatgaacaccgcactg
agcctgaaggtgcaacaggagtgcctggctttagctgtgctggacatgctgagaataaag
caggagactggctacagccttccaaagctcttcagcaacatcagctacaaaagctgtgtc
cccaagagtctgcagtatcagatccagcagcacagcttcctgacccgcagacggatccgc
cagagggtgcagaggtctcttcttagaatcagcacctgcaatgcccaaattcagcacctg
aagatcaaataccttttggacctggagaagttggagcccaatttcggaatggagatgttc
ccggtccagacaccctctgcaggacgggcacatggcacagaaaaggtcatccgtgtgtgc
gggggaagtggaatttattggcgtttaaaggacagtgagatatggcaggtgttctgtgac
tttccggagatcactgatatcggcattacacaggcgtactatgagaagaggcctgtggaa
agcagaattgtcaccatcaccaagcaagacaacaaggtgctggaagctgagttccttggc
caaaaagaggcactgtcctttgtttcacttgtggatggatattaccggctcaccgtggat
acctaccattatttctgtgggaatgtggcaccaccacggctgctgtggagcattgagaac
cagtgtcatgggccaataacctctgagtttgcagtgaacaagctgaaaaaattggggagc
actggggggcagtacatattgcgttgcagcccacagcacttcaaccggtacatcctcacc
atctgcactgagactcccttgggcagggactacaaagattgcctaatcaccaagacggac
tctggctactctttgcttggtgtcactcggcacttctacagcctgaaggaactgctagag
tattatcagagcgcaactctgcatgccaagaaagtcaccatccaactccagagctgctac
ccacccatgcccaaagaaaaatccaatttgttgattatgagaggcagctgcccccagccc
cagacctcccccaccaaatgtcggcgcaacatcagtcagatgacattccagaacatcagg
ccagagaccatcatctggggtgagagcctggggcagggatccttcactaagatcttccgg
ggcatcaagcgagacattgataatgaggagagctacgagacggacgtactgctgaaggtg
ctggacatcacatacaggaacttcaatgagtcctttctggaagcagccagtgtgatgagt
ctgatctcccacaaacatctcgtcctgctgcatggaatctgcgtggggacagacagtatc
atggtccaggaatatgtaaagcttggacctctggacatttatctgaagaaacagaaggac
ggcagtcggatcacggccaggtggaagcttgaagtggccaagcagcttgcgtataccctc
agcttcctgcgagacaagaatatcatccatggaaatgtgtcaactaagaacattctgctc
agccgggagggagacagcagcaccgggagtcccccttttattaaactcagtgactccgga
gtcagcatcacagtcatgaccaaagaattgctgacggaccgcattccctgggtggcacca
gaatgtgtgcgtgatcctaggagcctggttcaggagtcagactgctggagttttggtgcc
acactctgggagatcttcaacggcggaagtatacctctgagtgtcctggagccaacggcg
aaggtgaaattttaccaggatcagctccagctgccaatcctgaagtggacagaactggct
aatctgataaactgctgcatgaattacagacccttcctgcgcccatccttccgagctata
atcagagacctcaataatctcatcacatccgattatgagctcctagtagacctgtctact
ggagatctgccagttaaggacaacttttggcgatgtatgagtctcacagacctccaggac
cccccattctatgaggaacgccatttaaaatacatatctgctttgggaaagggcaacttc
ggcagtgtggatctgtgccgctatgaccctcttggggacaacacaggtgacctggtggca
gtgaagaagctgcagcaaagtacagctgagcatctgcgggactttgagagagaaactgag
atcctgcggtccttacacaatgatttcattgtgcagtacagaggcgtgtgttatagtgca
ggaaggaagaatctccggttgatcatggagtacctcccaaacggatgcttgcgggaatat
ttacagaaccaccgagattacctgtgccaggggaaactactgctttatgcaaggcaaatc
tgcaagggtatgcagtaccttggagagaagcgctatgtacaccgggatttggccaccaga
aatattttggtagagaacagcaaccatgtgaagattggagactttgggttggccaagatc
ctcccccaggacaaagagtactatgtggttcatgagcggggggaaagtcccatcttctgg
tatgctccagagtctctagccgatagcatcttctcccgccactctgatagctggagtttt
ggggtcctcctttatgagctgtttacctatggtgaaaaaagtagcagtcctccctcggag
tttctgcagctgatagggtctgggaaccagctgcagctggttaaccaattgctgaaactg
ctgacagggggcatccgactgcctgaacccccagaatgccctgcagaggtccatggtctg
atgctgcagtgctgggccctccaacctgctgagaggccaaccttcagcgatctggagcaa
aggatggagaaatacaaacaaaaaattgacccttaa
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