Geobacillus thermodenitrificans: GTNG_0922
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Entry
GTNG_0922 CDS
T00496
Name
(GenBank) Pyruvate dehydrogenase (lipoamide)alpha subunit
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
gtn
Geobacillus thermodenitrificans
Pathway
gtn00010
Glycolysis / Gluconeogenesis
gtn00020
Citrate cycle (TCA cycle)
gtn00620
Pyruvate metabolism
gtn00785
Lipoic acid metabolism
gtn01100
Metabolic pathways
gtn01110
Biosynthesis of secondary metabolites
gtn01120
Microbial metabolism in diverse environments
gtn01200
Carbon metabolism
gtn01210
2-Oxocarboxylic acid metabolism
Module
gtn_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
gtn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
GTNG_0922
00020 Citrate cycle (TCA cycle)
GTNG_0922
00620 Pyruvate metabolism
GTNG_0922
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
GTNG_0922
Enzymes [BR:
gtn01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
GTNG_0922
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
HupE_UreJ
RNase_J_C
Motif
Other DBs
NCBI-ProteinID:
ABO66300
UniProt:
A4ILU6
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Position
994564..995673
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AA seq
369 aa
AA seq
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MGVKTSQFPFAEQLEKVAEQFPTFQILNEEGEIVNKEAMPDLSDEQLKELMRRMVYTRIL
DQRSISLNRQGRLGFYAPTAGQEASQIASHFALEKEDFILPGYRDVPQLVWHGLPLYQAF
LFSRGHFHGNQIPEDVNALPPQIIIGAQYIQAAGVALGLKMREKKAVAITYTGDGGTSQG
DFYEGINFAGAFKAPAIFVVQNNRFAISTPVEKQTVAKTLAQKAVAAGIPGIQVDGMDAL
AVYAAVKAARERAINGEGPTLIETLCFRYGPHTMSGDDPTRYRSKELENEWAKKDPLVRF
RKFLEAKGLWSEEEENRVIEQAKEDIKEAIKKADETPKQKVTDLISIMYEELPANLKEQY
EIYKEKESK
NT seq
1110 nt
NT seq
+upstream
nt +downstream
nt
atgggtgtgaagacctcccagtttccgtttgcggagcagctcgagaaagtggccgagcag
tttccgacgttccaaattttgaatgaagaaggcgaaatcgttaataaagaggcgatgccg
gatttaagcgatgaacaactaaaagagctaatgcgccggatggtatatacgcgcattctt
gaccaacgctccatttccttaaaccgccaaggccgtctcggcttttacgcgccgactgcc
gggcaagaggcgagccaaattgccagccatttcgcgcttgaaaaagaggatttcattttg
ccgggataccgtgacgtcccacaactcgtttggcacgggctgccgctttatcaagcattc
ttgttctcacgcggccatttccatggaaaccaaattccagaagacgtcaatgccttgccg
ccgcaaatcatcatcggtgcacaatacattcaagcagccggtgtggcgctcggcttgaaa
atgcgtgaaaaaaaagcagtagccattacatacacgggcgacggcggtacatcgcaaggt
gacttctatgaggggatcaactttgctggggcgtttaaagcaccggccatctttgttgtg
caaaacaaccgatttgctatctcgacaccggtcgaaaagcaaacagtcgccaaaacgtta
gcacaaaaggcagttgctgccggtattccgggcatccaagtcgacggcatggatgcgctt
gcggtttatgcagcggtgaaggcagctcgcgagcgtgccattaacggtgaagggccgacg
ctcatcgaaacgctttgcttccgttacggtccgcacacgatgtccggtgacgatccgact
cgctatcgttcgaaagagcttgaaaacgaatgggcgaaaaaagatccgcttgtgcgtttc
cgcaagttcttagaagcgaaaggtttatggagcgaggaagaagaaaaccgcgtcatcgag
caagcgaaagaggacatcaaagaggcgattaaaaaagccgatgaaacgccgaaacaaaaa
gtaaccgacttaatcagcatcatgtacgaagagttgccggcgaacttaaaggaacagtat
gaaatttacaaagagaaggagtcgaagtaa
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