KEGG   Galeopterus variegatus (Sunda flying lemur): 103587478
Entry
103587478         CDS       T08727                                 
Symbol
MAPK11
Name
(RefSeq) mitogen-activated protein kinase 11 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
gvr  Galeopterus variegatus (Sunda flying lemur)
Pathway
gvr01522  Endocrine resistance
gvr04010  MAPK signaling pathway
gvr04015  Rap1 signaling pathway
gvr04068  FoxO signaling pathway
gvr04071  Sphingolipid signaling pathway
gvr04114  Oocyte meiosis
gvr04148  Efferocytosis
gvr04218  Cellular senescence
gvr04261  Adrenergic signaling in cardiomyocytes
gvr04370  VEGF signaling pathway
gvr04380  Osteoclast differentiation
gvr04550  Signaling pathways regulating pluripotency of stem cells
gvr04611  Platelet activation
gvr04613  Neutrophil extracellular trap formation
gvr04620  Toll-like receptor signaling pathway
gvr04621  NOD-like receptor signaling pathway
gvr04622  RIG-I-like receptor signaling pathway
gvr04625  C-type lectin receptor signaling pathway
gvr04657  IL-17 signaling pathway
gvr04658  Th1 and Th2 cell differentiation
gvr04659  Th17 cell differentiation
gvr04660  T cell receptor signaling pathway
gvr04664  Fc epsilon RI signaling pathway
gvr04668  TNF signaling pathway
gvr04670  Leukocyte transendothelial migration
gvr04714  Thermogenesis
gvr04722  Neurotrophin signaling pathway
gvr04723  Retrograde endocannabinoid signaling
gvr04728  Dopaminergic synapse
gvr04750  Inflammatory mediator regulation of TRP channels
gvr04912  GnRH signaling pathway
gvr04914  Progesterone-mediated oocyte maturation
gvr04917  Prolactin signaling pathway
gvr04926  Relaxin signaling pathway
gvr04932  Non-alcoholic fatty liver disease
gvr04933  AGE-RAGE signaling pathway in diabetic complications
gvr04935  Growth hormone synthesis, secretion and action
gvr04936  Alcoholic liver disease
gvr05014  Amyotrophic lateral sclerosis
gvr05020  Prion disease
gvr05022  Pathways of neurodegeneration - multiple diseases
gvr05132  Salmonella infection
gvr05133  Pertussis
gvr05135  Yersinia infection
gvr05140  Leishmaniasis
gvr05142  Chagas disease
gvr05145  Toxoplasmosis
gvr05152  Tuberculosis
gvr05161  Hepatitis B
gvr05163  Human cytomegalovirus infection
gvr05167  Kaposi sarcoma-associated herpesvirus infection
gvr05169  Epstein-Barr virus infection
gvr05170  Human immunodeficiency virus 1 infection
gvr05171  Coronavirus disease - COVID-19
gvr05205  Proteoglycans in cancer
gvr05208  Chemical carcinogenesis - reactive oxygen species
gvr05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
gvr05415  Diabetic cardiomyopathy
gvr05417  Lipid and atherosclerosis
gvr05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:gvr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103587478 (MAPK11)
   04015 Rap1 signaling pathway
    103587478 (MAPK11)
   04370 VEGF signaling pathway
    103587478 (MAPK11)
   04668 TNF signaling pathway
    103587478 (MAPK11)
   04068 FoxO signaling pathway
    103587478 (MAPK11)
   04071 Sphingolipid signaling pathway
    103587478 (MAPK11)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    103587478 (MAPK11)
  09143 Cell growth and death
   04114 Oocyte meiosis
    103587478 (MAPK11)
   04218 Cellular senescence
    103587478 (MAPK11)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    103587478 (MAPK11)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    103587478 (MAPK11)
   04613 Neutrophil extracellular trap formation
    103587478 (MAPK11)
   04620 Toll-like receptor signaling pathway
    103587478 (MAPK11)
   04621 NOD-like receptor signaling pathway
    103587478 (MAPK11)
   04622 RIG-I-like receptor signaling pathway
    103587478 (MAPK11)
   04625 C-type lectin receptor signaling pathway
    103587478 (MAPK11)
   04660 T cell receptor signaling pathway
    103587478 (MAPK11)
   04658 Th1 and Th2 cell differentiation
    103587478 (MAPK11)
   04659 Th17 cell differentiation
    103587478 (MAPK11)
   04657 IL-17 signaling pathway
    103587478 (MAPK11)
   04664 Fc epsilon RI signaling pathway
    103587478 (MAPK11)
   04670 Leukocyte transendothelial migration
    103587478 (MAPK11)
  09152 Endocrine system
   04912 GnRH signaling pathway
    103587478 (MAPK11)
   04914 Progesterone-mediated oocyte maturation
    103587478 (MAPK11)
   04917 Prolactin signaling pathway
    103587478 (MAPK11)
   04926 Relaxin signaling pathway
    103587478 (MAPK11)
   04935 Growth hormone synthesis, secretion and action
    103587478 (MAPK11)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    103587478 (MAPK11)
  09156 Nervous system
   04728 Dopaminergic synapse
    103587478 (MAPK11)
   04723 Retrograde endocannabinoid signaling
    103587478 (MAPK11)
   04722 Neurotrophin signaling pathway
    103587478 (MAPK11)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    103587478 (MAPK11)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    103587478 (MAPK11)
  09159 Environmental adaptation
   04714 Thermogenesis
    103587478 (MAPK11)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    103587478 (MAPK11)
   05208 Chemical carcinogenesis - reactive oxygen species
    103587478 (MAPK11)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    103587478 (MAPK11)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    103587478 (MAPK11)
   05161 Hepatitis B
    103587478 (MAPK11)
   05171 Coronavirus disease - COVID-19
    103587478 (MAPK11)
   05163 Human cytomegalovirus infection
    103587478 (MAPK11)
   05167 Kaposi sarcoma-associated herpesvirus infection
    103587478 (MAPK11)
   05169 Epstein-Barr virus infection
    103587478 (MAPK11)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    103587478 (MAPK11)
   05135 Yersinia infection
    103587478 (MAPK11)
   05133 Pertussis
    103587478 (MAPK11)
   05152 Tuberculosis
    103587478 (MAPK11)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    103587478 (MAPK11)
   05140 Leishmaniasis
    103587478 (MAPK11)
   05142 Chagas disease
    103587478 (MAPK11)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    103587478 (MAPK11)
   05020 Prion disease
    103587478 (MAPK11)
   05022 Pathways of neurodegeneration - multiple diseases
    103587478 (MAPK11)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103587478 (MAPK11)
   05418 Fluid shear stress and atherosclerosis
    103587478 (MAPK11)
   05415 Diabetic cardiomyopathy
    103587478 (MAPK11)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    103587478 (MAPK11)
   04932 Non-alcoholic fatty liver disease
    103587478 (MAPK11)
   04933 AGE-RAGE signaling pathway in diabetic complications
    103587478 (MAPK11)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    103587478 (MAPK11)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:gvr01001]
    103587478 (MAPK11)
Enzymes [BR:gvr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     103587478 (MAPK11)
Protein kinases [BR:gvr01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   103587478 (MAPK11)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH RIO1 Cas_CT1975 FTA2
Other DBs
NCBI-GeneID: 103587478
NCBI-ProteinID: XP_008567164
LinkDB
Position
Unknown
AA seq 363 aa
MSGPRPGFYRQELNKTAWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQ
SLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQ
ALSDEHVQFLIYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGNDYIDQLKRIMEVVG
TPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFHGANPLAIDLLGRMLVLDSDQRVSAA
EALAHAYFSQYHDPDDEPEAEPYDESIEAKEHTVEEWKELTYQEVLSFKPPEPPQPPGSL
EIQ
NT seq 1092 nt   +upstreamnt  +downstreamnt
atgtcgggcccccgccccggcttctaccggcaggagctgaacaagacggcgtgggaagtg
ccgcagcggctgcagggcctgcgaccggtgggctccggcgcctacggttccgtctgctca
gcctacgacgcgaggctgcgccagaaggtggcagtgaagaagctgtcgcgacccttccag
tcgctgatccatgcacgcaggacgtaccgcgagctgcggctgctcaagcacctgaagcac
gagaatgtcatcgggcttctggacgtcttcacgccggccacgtctatcgaggacttcagc
gaagtgtacttggtgaccaccctgatgggcgccgacctgaacaacattgtcaagtgtcaa
gcgctgagcgacgagcacgttcagttcctcatttaccagctgctgcgcgggctgaagtac
atccactcggctgggatcattcaccgggacctgaagcccagcaacgtggccgtgaatgag
gactgcgagctcaggatcctggactttgggctggcacgccaggcggacgaggagatgacc
ggatatgtggccacgcgctggtaccgagcacctgagatcatgctcaactggatgcactac
aaccagacagtggacatctggtctgtgggctgcatcatggctgaactgctccagggaaag
gccctcttcccaggaaatgactacattgaccagttgaagcgcatcatggaggtggtgggc
acaccgagccctgaggttctggcaaagatatcttcagaacatgcccggacgtacatccag
tccctgccccccatgccccagaaggacctcagcagcatcttccacggagccaaccccctg
gccatagacctccttggaaggatgctggtgctggacagtgaccagagggtcagtgcagcc
gaggcactagcccatgcctacttcagccaatatcatgaccccgatgatgagccagaggcc
gagccctacgatgaaagcatcgaggccaaggagcacacagtggaagagtggaaggagctc
acctaccaggaagtcctcagcttcaagcccccagagccaccacagccacctggcagcctg
gagatccagtag

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