Galeopterus variegatus (Sunda flying lemur): 103595656
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Entry
103595656 CDS
T08727
Symbol
PDE8B
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
gvr
Galeopterus variegatus (Sunda flying lemur)
Pathway
gvr00230
Purine metabolism
gvr01100
Metabolic pathways
gvr04927
Cortisol synthesis and secretion
gvr04934
Cushing syndrome
gvr05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
gvr00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
103595656 (PDE8B)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
103595656 (PDE8B)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
103595656 (PDE8B)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
103595656 (PDE8B)
Enzymes [BR:
gvr01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
103595656 (PDE8B)
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Paralog
GFIT
Motif
Pfam:
PDEase_I
PAS_9
PAS
PAS_3
PAS_4
PAS_8
Motif
Other DBs
NCBI-GeneID:
103595656
NCBI-ProteinID:
XP_008577321
LinkDB
All DBs
Position
Unknown
AA seq
647 aa
AA seq
DB search
MENSNIIACYNELIQIEHGEVRSQFKLRACNSVFTALDHCHEAIEITSDDHVIQYVNPAF
ERMMGYHKGELLGKELAELPKSDKNRADLLDTINTCIKKGKEWQGVYYARRKSGDSIQQH
VKITPVIGQGGKIRHFVSLKKLCCTTDNNKQIHKVHRDSGDNSQTEPHSFRHKNRRKESI
DVKSISSRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINIINAAQENSPVTVAEALDRV
LEILRTTELYSPQLGTKDEDPHTSDLVGGLMTDGLRRLSGNEYVFTKNVHQSHSHLTMPI
TINDIPPCIAQLLDNEESWDFNIFELEAVTHKRPLVYLGLKVFSRFGVCEFLNCSETTLR
AWLQVIEANYHASNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVD
HPGRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHYRTLRQ
AIIDMVLATEMTKHFEHVNKFVNSINKPMAAEIEGSDCECNPTGKNFPENQILIKRMMIK
CADVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIPKSQISFID
YFITDMFDAWDAFAHLPALMQHLANNYKHWKTLDDLKCKSLRLPSDS
NT seq
1944 nt
NT seq
+upstream
nt +downstream
nt
atggaaaatagcaacataattgcttgctataatgaactgattcaaatagaacacggggaa
gttcgctcacagttcaaattacgggcctgtaattcagtgtttacagcattagaccactgt
catgaagccatagaaataacgagtgatgaccacgtgattcagtatgtcaacccagccttc
gaaaggatgatgggctaccacaaaggtgagctgctggggaaagagctggcagagctgccc
aaaagcgacaagaaccgggcagatcttctcgacaccatcaacacgtgtatcaagaaggga
aaggagtggcagggggtttactacgccagacggaaatccggggacagcatccaacagcac
gtgaagatcaccccagtgattggccaaggagggaagattaggcattttgtctccctcaag
aagctgtgctgcaccactgacaataacaagcagattcacaaggttcatcgtgattcagga
gacaattctcagacagagcctcattcattcagacacaagaacaggcggaaagagtccatc
gatgtgaagtctatatcgtctcgaggcagtgatgcaccaagcctacagaatcgtcgctat
ccgtccatggcgaggatccactcgatgaccatcgaggctcccatcaccaaggttataaat
ataatcaatgcagcccaagaaaacagcccagtcacagtagcagaagccttggacagagtt
ctagagattttacggaccacagagctgtactcccctcagctgggcaccaaagatgaagat
cctcacaccagcgatcttgttggaggcctgatgactgatggcttgagaaggctgtcagga
aatgagtacgtgtttactaagaatgtacaccagagtcacagccaccttacgatgccaata
accatcaatgatattcccccttgtatcgctcagttacttgataatgaggaaagctgggac
ttcaacatctttgaattggaagcagttacccataaaaggccattggtttatctgggctta
aaggtcttctcccggtttggagtatgtgaatttttaaactgttctgaaaccactcttcgg
gcctggctgcaagtgattgaagccaactaccacgcctccaatgcctaccataattccacc
cacgctgcagacgtcctgcatgccactgccttcttcctgggaaaggagagagtgaaggga
agcctcgatcagctggatgaagtggcagccctgattgctgccacagtccatgacgtggat
cacccaggaaggaccaactctttcctgtgcaacgcgggcagtgaacttgccgtgctctat
aatgacactgctgtcttggagagccaccacacagccctggccttccagctcacggtcaag
gacactaaatgcaacattttcaagaatattgacaggaatcattatcgaacactgcgccag
gctattattgacatggttttggcaacagagatgacaaaacactttgaacatgtgaacaaa
tttgtgaacagcatcaacaagccaatggcagctgagattgagggcagcgactgtgaatgc
aaccctactgggaagaactttcctgaaaaccaaatcctgatcaagcgcatgatgattaag
tgtgctgatgtggccaatccatgccgtcccttggacctgtgcattgaatgggccgggagg
atctctgaggagtattttgcacagactgatgaagagaagagacaggggctacctgtggtg
atgccagtgtttgaccggaatacttgtagcatccccaagtcccagatctccttcattgac
tacttcataacagacatgtttgatgcttgggatgcctttgcacatctgccagccctgatg
caacacttggccaacaactacaaacactggaagacattagatgacctaaagtgcaaaagt
ttgaggcttccatctgacagctaa
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