Galeopterus variegatus (Sunda flying lemur): 103596387
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Entry
103596387 CDS
T08727
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
gvr
Galeopterus variegatus (Sunda flying lemur)
Pathway
gvr00010
Glycolysis / Gluconeogenesis
gvr00020
Citrate cycle (TCA cycle)
gvr00620
Pyruvate metabolism
gvr00785
Lipoic acid metabolism
gvr01100
Metabolic pathways
gvr01200
Carbon metabolism
gvr01210
2-Oxocarboxylic acid metabolism
gvr04066
HIF-1 signaling pathway
gvr04922
Glucagon signaling pathway
gvr05230
Central carbon metabolism in cancer
gvr05415
Diabetic cardiomyopathy
Module
gvr_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
gvr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
103596387 (PDHA1)
00020 Citrate cycle (TCA cycle)
103596387 (PDHA1)
00620 Pyruvate metabolism
103596387 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
103596387 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
103596387 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
103596387 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
103596387 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
103596387 (PDHA1)
Enzymes [BR:
gvr01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
103596387 (PDHA1)
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GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
103596387
NCBI-ProteinID:
XP_008578234
LinkDB
All DBs
Position
Unknown
AA seq
407 aa
AA seq
DB search
MLVNITAAKLSLVILALAIPLGRDATLLSVGKDGQKASRVLVASRNFANDATFEIKKCDL
HRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVG
LEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRRGGCAKGKGGSMHMYAKNFYGG
NGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICE
NNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILME
LQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVR
KEIEDAAQFATADPEPPLEELGYHIYSSDPPFEVRGANQWIKFKSVS
NT seq
1224 nt
NT seq
+upstream
nt +downstream
nt
atgttagttaatataactgcagccaagctttcacttgtaattctggctctagcaattccc
ctaggacgtgatgcaactctgcttagtgtgggcaaagatggtcaaaaggcaagcagagtg
ctggtggcatcccgtaattttgcaaatgatgctacatttgaaattaagaaatgtgacctt
caccggctggaagagggccctcccgtcacgacagtgctcacgagggaggacggactgaaa
tactacaggatgatgcagactgtacgccgaatggagttaaaggcagatcagctgtataaa
cagaaaattatccgtggtttctgtcacttgtgtgatggtcaggaagcttgctgtgtgggc
ctggaggccggcataaatcccacggaccatctcatcacagcctatcgggctcacggcttt
accttcacacggggcctttctgtccgagaaattcttgcagagcttacagggcgaagaggc
ggttgtgctaaagggaaaggaggatcgatgcatatgtatgccaagaacttctacgggggc
aatggcatcgtcggagctcaggtgcccctgggagctgggattgccctggcctgtaagtat
aatggaaaagatgaggtctgtctgactttatatggcgatggcgctgctaatcagggtcag
atatttgaagcttacaatatggcagctttgtggaaattaccttgcattttcatctgtgag
aataaccgctatggaatgggaacatctgttgagagagcggcagccagcactgattactac
aaaagaggcgattttattcctgggctgagggtagatggaatggatatcttgtgtgtccga
gaggcgacaaggtttgcagctgcctattgtagatctgggaagggacccatcctgatggag
ctgcagacctaccgttaccatggacacagtatgagtgatcctggggtcagttaccggaca
cgagaagaaattcaggaagtgagaagtaagagtgaccctattatgcttctcaaggataga
atggtgaacagcaaccttgccagtgttgaagagttgaaggaaattgatgttgaagtgagg
aaagaaattgaggatgctgcccagtttgccacagctgatccagagccgcctctggaggaa
ctaggctatcacatctactccagtgatccaccttttgaagttcgcggtgccaatcagtgg
atcaagtttaagtccgtcagttaa
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