Halomonas sp. GFAJ-1: BB497_13385
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Entry
BB497_13385 CDS
T05375
Name
(GenBank) bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase
KO
K01682
aconitate hydratase 2 / 2-methylisocitrate dehydratase [EC:
4.2.1.3
4.2.1.99
]
Organism
hag
Halomonas sp. GFAJ-1
Pathway
hag00020
Citrate cycle (TCA cycle)
hag00630
Glyoxylate and dicarboxylate metabolism
hag00640
Propanoate metabolism
hag01100
Metabolic pathways
hag01110
Biosynthesis of secondary metabolites
hag01120
Microbial metabolism in diverse environments
hag01200
Carbon metabolism
hag01210
2-Oxocarboxylic acid metabolism
hag01230
Biosynthesis of amino acids
Module
hag_M00009
Citrate cycle (TCA cycle, Krebs cycle)
hag_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
hag_M00012
Glyoxylate cycle
Brite
KEGG Orthology (KO) [BR:
hag00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
BB497_13385
00630 Glyoxylate and dicarboxylate metabolism
BB497_13385
00640 Propanoate metabolism
BB497_13385
Enzymes [BR:
hag01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.3 aconitate hydratase
BB497_13385
4.2.1.99 2-methylisocitrate dehydratase
BB497_13385
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Gene cluster
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Motif
Pfam:
Aconitase_2_N
Aconitase_B_N
Aconitase
Ketoacyl-synt_C
Motif
Other DBs
NCBI-ProteinID:
AVI63626
UniProt:
H0IYQ6
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Position
2973579..2976182
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AA seq
867 aa
AA seq
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MLEAYRQHVEERAAEGVPPKPLNAEQVASVIELLKNPPAGEEEVILDLITNRVPPGVDEA
AYVKAGFLTAIAKGEATSPLIDKIHAVKLLGTMQGGYNIVSMVELLDNEELAREAGEQLK
HTLLMFDAFHDVEERAKNGNNVAKDVIQSWADAEWFLSKPALEEKITLTVFKVPGETNTD
DLSPAPDAWSRPDIPLHANAMLKNEREGIEPEVPGTTGPLKQIEEVKAKGFPVAYVGDVV
GTGSSRKSATNSVLWFFGDDLPYVPNKRAGGFCFGNKIAPIFFNTMEDSGALPIEMDVAN
LAMGDVIDVYPYEGKVCKHGTDEVVSTFELKTQLILDEVRAGGRIPLIIGRGLTGKARES
LGLEQSDVFRLPDQPKDTGKGFTLAQKMVGKACGLDGVRPGMYCEPKMTTVGSQDTTGPM
TRDELKDLACLGFQADLVMQSFCHTAAYPKPVDVDTHHTLPDFIMNRGGVSLRPGDGIIH
SWLNRMLLPDTVGTGGDSHTRFPLGISFPAGSGLVAFAAATGVMPLDMPESVLVRFKGTR
QPGVTLRDLVHAIPLYAIKKGLLTVEKSGKKNAFSGRVLEIEGLEELTVEQAFELSDASA
ERSAAGCTITLSEESVTEYLKSNITLLKWMIANGYGDERTISRRIEGMEAWLANPHLMRA
DKDAEYAEVIEIDLSEIKEPVLCAPNDPDDARLLSDVAGQKIDEVFIGSCMTNIGHFRAA
GKLLEKQPAGSLKTRLWLAPPTKMDQHQLTEEGYYGIYGRAGARMEMPGCSLCMGNQARV
AAKSTVVSTSTRNFPNRLGDGANVYLASAELAAVAAVEGRLPSVEEYQRYMSEFDAMAGE
IYRYMNFHEIEEYQKIASNVIPVAQEV
NT seq
2604 nt
NT seq
+upstream
nt +downstream
nt
gtgcttgaagcttaccgccaacatgtcgaggaacgcgctgctgagggcgtcccgcccaag
cccctaaatgctgagcaagtcgcttccgtaatcgagctgctgaaaaatccgccggcgggt
gaagaagaagttattcttgacttaatcaccaaccgtgtaccgccaggcgttgatgaagct
gcttatgttaaagcaggtttcttaaccgcgattgccaaaggggaagctacctctccgcta
atcgacaaaatccatgctgttaaactgcttggcaccatgcaaggcggttacaacatcgtc
tctatggttgaactgctggataatgaagagctggctcgtgaagccggcgaacagctgaag
cacacgctgttgatgtttgacgctttccacgatgttgaagagcgcgctaaaaatggcaac
aacgtcgccaaagatgtcattcaatcctgggctgacgcagagtggttcctttccaagcct
gcgctggaagagaaaatcacgttgacggtcttcaaggtgcctggcgaaaccaacaccgat
gacctctcacctgcccctgatgcttggtctcgccctgatattccgttacatgccaacgct
atgcttaaaaatgagcgcgaaggtatcgagccggaagtaccaggcaccactggcccgcta
aaacagatcgaagaagtaaaagccaagggcttccccgttgcttacgtgggtgacgtggta
ggtaccggctcttcgcgcaagtccgccactaactcggttctgtggttcttcggcgatgat
cttccctacgtgccaaacaaacgtgcaggcggcttctgctttggtaacaaaattgctccg
atcttctttaatactatggaagactctggcgcgttaccgattgaaatggacgtcgccaac
ttagcaatgggcgacgtcatcgacgtttacccctacgaaggcaaagtgtgcaagcacggc
accgacgaagtggtttccactttcgagctaaaaactcagctaattctggatgaagtacgc
gcgggtggccgcattccgctgatcatcggccgtggcttaaccggcaaagcgcgtgaatct
ctgggccttgaacagtctgacgtattccgcctgcctgaccagccaaaagacacgggtaag
ggctttacacttgctcagaaaatggtcggtaaggcgtgcggcctggacggcgttcgtcct
ggcatgtactgcgaacccaaaatgaccacggtcggttcccaggacaccactggcccgatg
acccgtgatgagctgaaagacctagcgtgcctgggcttccaagccgatctggttatgcaa
tctttctgccataccgctgcatacccgaagccggtagacgttgatacgcaccacacactt
cccgacttcattatgaaccgcggcggcgtatcactgcgccccggtgatggcatcattcac
agctggcttaaccgcatgctgctgcctgacaccgtcggcaccggcggcgactcccacacc
cgcttcccgctgggcatctcgttcccagccggttcaggtttggtggcgtttgctgcagcc
accggcgttatgccgcttgatatgccggagtctgtactggtgcgctttaaaggtactcgt
caacctggcgttaccctgcgcgacctggttcacgctatcccgctttacgccatcaagaaa
gggcttctcaccgtcgagaaatccggtaagaaaaacgccttctccggccgcgtactagag
attgaaggccttgaagagctgacggtagagcaagccttcgagctttctgatgcctctgct
gagcgtagcgctgctggctgtaccattacgctgtctgaagagagcgttactgaataccta
aaatcgaacatcacactgctgaagtggatgattgcgaatggttacggcgatgagcgtacc
attagccgccgcatcgaaggcatggaagcatggcttgctaacccgcatttgatgcgcgct
gataaagatgcagaatacgccgaggttattgaaattgacctcagcgagattaaagagccg
gtgctttgcgctccgaacgacccagacgatgcgcgcttactgtctgacgttgcgggccaa
aagatcgatgaagtattcatcggctcgtgcatgaccaacatcggccacttccgcgctgcc
ggcaagctgcttgagaaacaacctgcaggcagcctgaagactcgtctatggctggcaccg
cccaccaagatggatcagcaccagctgaccgaagagggttactacggcatttacggccgt
gcaggtgcccgtatggaaatgccgggatgttcactgtgtatgggtaaccaggcacgcgtt
gctgcgaaaagcaccgtcgtgtctacgtctacacgtaacttcccgaaccgtttaggcgat
ggtgccaatgtctacctcgcctcagcggaattggcagcggtcgccgctgtagaaggccgc
ctgccaagcgttgaagagtaccagcgctacatgagcgaatttgacgctatggcaggagag
atatatcgttacatgaacttccacgaaatcgaggagtatcaaaaaatcgcctcgaacgtg
attccggttgcacaagaagtttaa
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