Hipposideros armiger (great roundleaf bat): 109396353
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Entry
109396353 CDS
T04661
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
hai
Hipposideros armiger (great roundleaf bat)
Pathway
hai00270
Cysteine and methionine metabolism
hai00480
Glutathione metabolism
hai01100
Metabolic pathways
hai01240
Biosynthesis of cofactors
hai04216
Ferroptosis
Module
hai_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
hai00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
109396353 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
109396353 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
109396353 (GCLC)
Enzymes [BR:
hai01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
109396353 (GCLC)
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Ortholog
Paralog
GFIT
Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
109396353
NCBI-ProteinID:
XP_019523631
EnsemblRapid:
ENSHARG00000013973
UniProt:
A0A8B7TD52
LinkDB
All DBs
Position
Unknown
AA seq
638 aa
AA seq
DB search
MGLLSQGSPLSWEETKRHADHVRRHGILQFLHIYNAVKDRHKDVLKWGDEVEYMLVSFDH
ENKKVQLVLSGEEVLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMRQRRKEATSLLKENQALCTITSFPRLGCPGFTLPEFKPNPVEGGASKSLFFPDEAI
NRHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPEDDEAVMASKPDHIYMDA
MGFGMGNCCLQVTFQACSIAEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVI
SASVDDRTREERGLEPLKNNNYRISKSRYDSIDSYLSECGEKYNDIELTIDKEIYKQLLQ
EGIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVL
QGMFYFRKDICKAGGNAVVDGCGKAQNSSELAAEEYTLMSIDTIINGKEGVFPGLIPVLN
SYLENMEVDVDTRCSILNYLKLIKKRASGELMTVARWMREFISNHPDYKQDSVITDEMNY
SLISKCNQIANELCECPELLGPAFRKAKYSGSKTDPSN
NT seq
1917 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcccaaggctcgccgttgagctgggaggagaccaagcgccacgccgac
cacgtgcggcggcacgggatccttcagttcctgcacatctacaacgccgtcaaggaccgg
cacaaggatgtgctcaagtggggcgacgaggtggaatacatgttggtgtctttcgatcat
gaaaataaaaaagtccaattggtcctgtctggagaggaagttcttgaaactctacaagaa
aagggggaaaggacaaacccaaaccatcctaccctttggagaccggagtatgggagttac
atgattgaagggacgcccggacagccatacggaggaacgatgtccgagttcaacacggtc
gaagacaacatgagacaacgccggaaggaggccacgtctctattaaaagaaaatcaggct
ctttgcaccataacttcatttcccagattaggctgtcctgggttcacgctgcctgaattc
aaacccaacccagtcgaaggaggagcctccaagtccctcttctttcccgatgaagcaata
aacagacacccccgcttcagcaccctaacaagaaatattcgacataggagaggagaaaaa
gttgtcatcaatgtaccaatatttaaggacaagaatacaccatctccatttatagaaacc
tttcctgaggatgatgaggcagtgatggcttctaagcccgatcatatttacatggatgcc
atgggatttgggatgggcaattgctgtcttcaggtaacgttccaggcctgcagcatagct
gaggctagatacctttatgaccagttggccactatctgcccaattgtcatggctttgagt
gctgcgtctcccttttaccgaggctatgtgtcagacattgattgtcgctggggagtgatt
tctgcatctgtagatgatagaactcgggaggagagaggactggagccactgaagaacaat
aactataggattagtaaatcccgatatgattcaatagatagttatttatccgagtgtggt
gagaaatataatgacatcgagttgacaatagataaagaaatctacaaacaactgttgcag
gaaggcattgatcatctcctggctcagcatgtcgctcatctctttattagagacccactg
acgctgtttgaagagaaaatacacctggatgatgccaatgagtctgatcattttgagaat
attcagtccacaaattggcagacaatgagatttaagcctcctcctccaaactcagacatt
ggatggagagtagaattccgacccatggaggttcagttaacagacttcgagaattctgcg
tatgtggtgtttgtggtgctgcttactagagtgatcctttcatacaagttggattttctc
attccactgtcaaaggtcgatgaaaacatgaaagtagcccagaaacgagatgctgttcta
cagggaatgttctatttcaggaaggatatttgcaaagcaggtggcaacgccgtggtggat
ggctgtggcaaggcgcagaacagctcggagctggccgcagaggaatacaccctgatgagc
atagacaccatcattaacgggaaggaaggtgtgtttcctgggctgatcccagttctgaac
tcctaccttgagaacatggaagtggatgtggacaccagatgtagcattctgaactaccta
aagctgattaagaagagagcatctggagaactaatgacagttgcaagatggatgcgggaa
tttatctcaaaccatcctgactacaagcaagacagtgtaataactgatgaaatgaactat
agccttatttcaaagtgtaaccaaattgcgaatgaattatgtgaatgcccagagttactt
gggccagcatttaggaaagcaaaatatagtggaagtaaaactgacccttccaactag
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