Haloprofundus sp. MHR1: FCF25_02520
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Entry
FCF25_02520 CDS
T05952
Name
(GenBank) thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
halm
Haloprofundus sp. MHR1
Pathway
halm00010
Glycolysis / Gluconeogenesis
halm00020
Citrate cycle (TCA cycle)
halm00620
Pyruvate metabolism
halm00785
Lipoic acid metabolism
halm01100
Metabolic pathways
halm01110
Biosynthesis of secondary metabolites
halm01120
Microbial metabolism in diverse environments
halm01200
Carbon metabolism
halm01210
2-Oxocarboxylic acid metabolism
Module
halm_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
halm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
FCF25_02520
00020 Citrate cycle (TCA cycle)
FCF25_02520
00620 Pyruvate metabolism
FCF25_02520
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
FCF25_02520
Enzymes [BR:
halm01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
FCF25_02520
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Motif
Pfam:
E1_dh
DXP_synthase_N
Transketolase_N
Motif
Other DBs
NCBI-ProteinID:
QCJ46060
UniProt:
A0A4D7H501
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Position
530140..531186
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AA seq
348 aa
AA seq
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MHRLIDDRSLSESSLSADDARAAYVDMVRTRRFDERALALQRRGWMSGYPPFLGQEASQV
GAAHAMADDDWLFPTYRSNALQIARGVPMSDILRFRRGYPEYHSDHDVPVFPQAVPIASQ
IPHAAGAGMARNYRGNDEAMLVCFGDGATSEGDFHEGLNFAGVFDAPVVFFCENNDWAIS
LPRERQTASESIAVKAEAYGLEGIQVDGNDPLAVREAVEQGLEAARSGSPVLVESLTYRR
GAHTTADDPSVYRDDDPDLPEWRIRDPLERFEEFLRAEGLVDDEFVESAYDDANEELSEA
VEVAESGPRADPDELFDFVYESLPPELEAQRERMHRSIETHDPQELDR
NT seq
1047 nt
NT seq
+upstream
nt +downstream
nt
atgcatcgactcatcgacgaccggtcgctctcggagtcgtcgctctcggccgacgacgcc
cgggcggcgtacgtcgacatggtccgaacgcggcgattcgacgagcgcgcgctcgcgcta
cagcggcgcgggtggatgagcgggtatcccccgtttctcggacaagaggcgtcgcaggtc
ggcgcggcccacgcgatggccgacgacgactggctcttcccgacctaccgttcgaacgcg
ctccagatcgcccgcggcgtcccgatgagcgacatcctccgcttccggcgcggctacccc
gagtaccactccgaccacgacgtgccggtgttcccgcaggcggttcccatcgccagccag
attccgcacgccgccggcgcggggatggcgcgcaactaccgggggaacgacgaggcgatg
ttggtctgcttcggcgacggcgcgacgagcgagggcgacttccacgaggggctgaacttc
gcgggcgtcttcgacgcgccggtcgtcttcttctgtgagaacaacgactgggccatctca
ctgccgcgcgagcgacagaccgccagcgagtctatcgccgtcaaagccgaggcgtacggt
ctcgagggaatccaggtcgacggcaacgacccgctcgcggtccgcgaggcggtcgagcag
gggctcgaagccgctcgaagcggttcgcccgtgctggtcgagagcctcacctaccgccgc
ggcgcgcacacgaccgccgacgacccctccgtctatcgcgacgacgaccccgacctcccc
gagtggcgcatccgcgacccgctcgaacggttcgaggagttcctccgcgcggagggcctc
gtcgacgacgagttcgtcgagagcgcgtacgacgacgccaacgaggagctgtccgaggcg
gtcgaagtcgccgaatccggtccccgcgccgaccccgacgaactgttcgacttcgtctac
gagtcgctgccgccggagctcgaagcccagcgcgagcggatgcaccgctcgatcgaaacc
cacgacccccaggaactggaccgatag
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