Natranaeroarchaeum sulfidigenes: AArcS_2643
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Entry
AArcS_2643 CDS
T07875
Symbol
folC2
Name
(GenBank) Folylpolyglutamate synthase and Dihydropteroate synthase
KO
K24102
dihydrofolate synthase / dihydropteroate synthase [EC:
6.3.2.12
2.5.1.15
]
Organism
hara
Natranaeroarchaeum sulfidigenes
Pathway
hara00790
Folate biosynthesis
hara01100
Metabolic pathways
Brite
KEGG Orthology (KO) [BR:
hara00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
AArcS_2643 (folC2)
Enzymes [BR:
hara01000
]
2. Transferases
2.5 Transferring alkyl or aryl groups, other than methyl groups
2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
2.5.1.15 dihydropteroate synthase
AArcS_2643 (folC2)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
AArcS_2643 (folC2)
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Gene cluster
GFIT
Motif
Pfam:
Pterin_bind
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
QSG03839
UniProt:
A0A897MY52
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All DBs
Position
complement(2527630..2530086)
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AA seq
818 aa
AA seq
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MKFHDAANFLYDLRRFGPRPGIESTADLLAALDDPHDDLDCVQVAGSNGKGSTARMTESI
LREAGLTVGLFTSPHLEDLRERIRVDGRKIPKAAVCEFVEHVEGHVRDRGAEGISPTFFE
ATTAMALWQFAREGVDVVVLEVGIGGKKDATSVVDPVASAVTSVTLEHTGVLGDTIEEIA
QDKAHVAPADAPLVTGVDGVALDAVRSIAGEVVTVGAGGDVVPTYGGRTNHTEAAIGIEG
PDWSVDTRLPTLGAHQSENAAIAATLARHVIDEQGGDLAETTIETGLRRSHWPGRFEVVE
QEPLTVLDGAHNPGACERIAEVLTEFEYDDLHLVFGAMHDKDHRAMADTLPTADRVVACQ
PDLDRAEDEAVLARVFEASGAEEVVTNNSVEGALSRALREADADDCVLVTGSLFTVAEAR
TRWTRLQVPKRVEEINDARAVLSDAHVTDPGVWRMRGKGVHRVLKTRVQKRQAQYLKEEL
LSLGGECALSGLNDQDDVIIDVVMMATMAQFNRLVDKLDGQPYGLSVVGEEIRETLGIRT
AEPDSGYPWDDGTAVMGILNITPDSFHDGGEYNAVAEARERAERMVANGAAILDVGGEST
RPGAEPVSVDEEIDRVVPVIEAIADLDAMISVDTRKAEVARAAVEAGADIINDVSGLEDP
EMRFVAAEHDAALVVMHSVDAPVDPDTEIEYDDVVEDVIDQLAERVLLAEKAGLDREQIV
VDPGLGFGKSSAESFELLDRCDELAALGCPIMVGHSHKSMFALSGQDADERLPSTIAGTT
LATERGVDIVRVHDVAENAAAVTVAETAAGTMSSGTDD
NT seq
2457 nt
NT seq
+upstream
nt +downstream
nt
atgaagttccacgacgcggcgaacttcctctacgatctgcgtcggttcggtccacgccca
gggatcgagtcgaccgcggatctgctcgccgcactggacgacccacacgacgatctcgac
tgcgtgcaggtcgctggctcgaacggcaagggcagcacggcccgaatgacggagtcgatc
ctccgggaggccggtctcaccgtcggactctttacgtcgccacatctggaggacctgcgc
gaacgcattcgcgtcgacgggcgcaagatcccgaaagcggccgtctgcgagttcgtcgag
cacgtcgaggggcacgtccgcgaccgaggtgctgaggggatctctcccactttcttcgag
gcgacgacggcgatggcgctctggcagttcgcccgcgagggcgtcgacgtcgtcgtgctg
gaggtcggcatcggcggcaagaaagatgccacgagcgtcgtcgatccggtcgccagcgca
gtcacctccgtcacgctggaacacaccggcgtcctcggcgatacaatcgaggagatcgca
caggacaaagcacacgtcgcacccgccgatgcgccactggtcacgggcgtcgacggtgta
gcgctcgacgcggtccgctcgattgctggtgaggtcgtcaccgtcggcgcgggcggcgat
gtcgtaccgacctacggtggccggacgaatcacaccgaagccgcaatcggaatcgagggg
ccggactggtcagtcgacacgcggctcccgacactgggtgcccaccagtccgagaacgcg
gccatcgcggcgacgctcgcccggcacgtcatcgacgagcaggggggcgacctcgccgaa
accacgatcgagaccggcctccggcgctcgcactggcccggccggttcgaggtcgtggag
caggagcccctgaccgtgctggacggcgcacacaaccctggtgcctgcgagcggatcgcg
gaggtcctgacggagttcgagtacgacgacctccatctcgtcttcggtgcgatgcacgac
aaggaccaccgcgctatggccgacacgctccccactgccgatcgcgtcgtggcgtgtcag
cccgatctggaccgtgccgaggacgaggccgtacttgcgcgtgtgttcgaggccagcggg
gccgaggaggtcgtcacgaacaactccgtcgagggcgcgctctcgcgagcgctgcgcgag
gccgacgccgacgactgcgtgctcgttactggctcgctctttacagtcgccgaggcccgg
acgcgatggacgcgcttgcaggtgccaaaacgagtcgaggagataaacgatgcccgcgcg
gtcctctcggacgcccacgtcaccgatccgggcgtctggcggatgcgcggcaaaggagtc
caccgcgtgctcaaaacccgcgtacagaagcgacaggcccagtatctcaaggaggaactg
ctcagcctcggcggcgagtgtgccctttccgggctgaacgatcaggacgacgttatcatc
gacgtcgtgatgatggcgacgatggcccagttcaaccggctcgtggacaaactcgacgga
cagccctacggcctctcggtcgtcggcgaggagatccgcgagactctggggatccgtacg
gccgagcccgactccggctacccgtgggacgacgggaccgccgtgatgggcatcctcaac
atcacgccggatagctttcacgatgggggcgagtacaacgccgtcgccgaggcccgcgag
cgcgccgagcggatggtcgcaaacggcgcggcgatcctcgacgtgggcggcgagagcaca
cgtcccggtgccgagccggtgagcgtcgacgaggagatagatcgcgtcgtcccggtgata
gaggcaatcgccgacctggatgcgatgatctccgtggacacccgcaaagccgaggttgcc
cgggccgccgtcgaggcgggtgcggacattatcaacgacgtgtccggcctcgaagatcca
gagatgcgctttgtcgccgccgagcacgacgctgccctcgtcgtcatgcacagcgttgac
gcgccggtcgatcccgacaccgaaatcgagtacgacgacgtcgtcgaggacgtgatcgac
cagctcgcagaacgcgtcctgctcgccgagaaagcagggctcgaccgcgagcagatcgtt
gtcgatcccggactgggcttcggaaaaagttcggcggaaagcttcgagctactggaccgg
tgtgacgaactcgccgcgcttggttgtccgatcatggtcggccattcgcacaagtcgatg
ttcgcgctgtccggccaagacgccgacgagcgcctgccgtcgacgatcgccggaacgacg
cttgcgaccgagcgcggtgtagatatcgttcgcgtgcacgacgtcgccgagaacgcggcg
gcggtgaccgtggccgagacggcggccggtaccatgtcgtccggaacggacgactga
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