Halorubrum sp. 2020YC2: KI388_02665
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Entry
KI388_02665 CDS
T08040
Name
(GenBank) thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
hazz
Halorubrum sp. 2020YC2
Pathway
hazz00010
Glycolysis / Gluconeogenesis
hazz00020
Citrate cycle (TCA cycle)
hazz00620
Pyruvate metabolism
hazz00785
Lipoic acid metabolism
hazz01100
Metabolic pathways
hazz01110
Biosynthesis of secondary metabolites
hazz01120
Microbial metabolism in diverse environments
hazz01200
Carbon metabolism
hazz01210
2-Oxocarboxylic acid metabolism
Module
hazz_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
hazz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
KI388_02665
00020 Citrate cycle (TCA cycle)
KI388_02665
00620 Pyruvate metabolism
KI388_02665
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
KI388_02665
Enzymes [BR:
hazz01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
KI388_02665
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GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Transketolase_N
DUF6110
DUF1815
HTH_41
Motif
Other DBs
NCBI-ProteinID:
QWC19891
UniProt:
A0A8E8EXW6
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Position
545468..546649
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AA seq
393 aa
AA seq
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MNENGADGADPDADPAADPAAPAADPLADEDLYRVLGPDGSPLPGATVPDLSDEQFRAIY
RDLVVTRRFDERAVSLQRQGRIGTYAPCAGQEGSAVGSTHALADRDLISYQYREHGAVVV
RDLLAEYLPYWMGHESGTEAIEDGNVFPLNIGIAAHLPHAVGAAWAFDYRDEDRVVACHF
GDGATSEGDFHEAMNFAGVFDTPTIFCCHNNGWAISIPESRQTASDTFAQKATAYGFDGV
RVDGTDPLASYAVTREAAERARGDTAGTEGEGPRPALIEFVEYRFGAHTTADDPTAYRDP
DDVDPWRALDPLDRMEAFLRETGRIDDEGVAAIREEADDVVADAIDFAESVEAGPSDMFG
DAYAELPPEIRRQRDELLAAVEEHGEDAFLREE
NT seq
1182 nt
NT seq
+upstream
nt +downstream
nt
atgaacgagaacggcgccgacggcgccgaccccgacgctgaccccgccgctgaccccgcc
gcccccgcggccgacccccttgccgacgaggacctctaccgcgtgctcggcccggacgga
agcccgctgccgggcgcaaccgttccggacctgtcggacgagcagttccgcgccatctac
cgcgacctcgtggtgacgcgccggttcgacgagcgggccgtgagcctccagcgacagggt
cggatcgggacgtacgcgccctgcgcgggtcaggaagggtcggcggtcgggtcgacgcac
gcgctcgcggaccgggacctgatcagctaccagtaccgcgagcacggcgcggtcgtcgtc
cgcgacctgctggccgagtacctcccctactggatgggtcacgagtcggggaccgaggcg
atcgaggacggcaacgtcttccctctcaacatcggtatcgcggcgcatctcccgcacgcg
gtcggcgccgcgtgggcgttcgactaccgcgacgaggaccgggtcgtcgcctgccacttc
ggggacggcgcgacgagcgagggcgacttccacgaggcgatgaacttcgcgggcgtgttc
gacacgccgacgatattctgctgtcacaacaacggctgggccatctcgatccccgagtcg
cgacagaccgcgagcgacaccttcgcgcagaaggcgaccgcctacggcttcgacggcgtc
cgcgtcgacgggaccgacccgctcgccagctacgcggtcacgcgggaggcggccgagcgc
gcgcggggcgatactgccggcaccgagggagagggaccgcgtcccgcgctcatcgagttc
gtcgagtaccggttcggcgcgcacacgaccgcggacgacccgaccgcctaccgcgacccc
gacgacgtggacccgtggcgcgcgctcgacccgctcgaccggatggaggcgttcctccgc
gagacggggcggatcgacgacgagggggtcgcggcgatccgcgaggaggcggacgacgtc
gtcgcggacgcgatcgatttcgcggagtccgtcgaggccggcccgagcgacatgttcggg
gacgcgtacgccgaactcccgccggagatccggcgccagcgcgacgaactgctcgcggcc
gtcgaggagcacggcgaggacgcgttcctgcgggaggagtag
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