Hippocampus comes (tiger tail seahorse): 109516203
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Entry
109516203 CDS
T04969
Symbol
gclc
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
hcq
Hippocampus comes (tiger tail seahorse)
Pathway
hcq00270
Cysteine and methionine metabolism
hcq00480
Glutathione metabolism
hcq01100
Metabolic pathways
hcq01240
Biosynthesis of cofactors
hcq04216
Ferroptosis
Module
hcq_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
hcq00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
109516203 (gclc)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
109516203 (gclc)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
109516203 (gclc)
Enzymes [BR:
hcq01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
109516203 (gclc)
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Paralog
GFIT
Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
109516203
NCBI-ProteinID:
XP_019726093
LinkDB
All DBs
Position
Unknown
AA seq
532 aa
AA seq
DB search
MGLLTQGSPLNWENTKKYADYIRSHGIIQFINIYNNLKDRQKDVLKWGDEVEYMLVELDD
KDEKVQLVLNGDEVLDTLQGQGEKINPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
ESNMGKRRREASSVLNQNEILCTITSFPRLGCPGFTKPEYPPTPFESGASKSLFFPDEAI
NHHPRFSTLTRNIRHRRGEKVAINVPIFKDKCTPSPFVETFPEDDGESARAALPDHIYMD
CMGFGMGNCCLQVTFQACSIDEARYLYDQLATFCPIVMALSAASPFYRGHVSDIDCRWGV
ISASVDDRTQEERGLKPLKNDKYRIFKSRYDSIDSYLSNCGNKYNDIDLTIDEDIYNQLL
GAGIDKLLAQHIAHLFIRDPLCVYEEKLQQDDENESDHFENIQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENAAYVVFVVLLTRVILSYKLDFLIPLSKVDENLKMAQKRNAV
KDGMFYFRKDIFKGCNPGLDGTSSAQNGLETDGANEEYTLMSIDTIINGQAS
NT seq
1599 nt
NT seq
+upstream
nt +downstream
nt
atgggtttactgactcaaggttcccccctcaactgggaaaacaccaagaagtatgcggat
tacatccgatcgcacggcatcattcagttcatcaacatttacaacaatttgaaggaccgg
cagaaggatgtactcaaatggggcgatgaggtggagtacatgttggtggaactggatgac
aaggatgaaaaggttcaactggtgttgaatggcgatgaagttttggataccctccaaggc
caaggtgaaaagataaatcccaaccatcccacgctttggaggccagaatatggcagctac
atgatagaaggaactccagggcagccgtatggcggcaccatgtcggagtttaacactgtc
gagagcaacatggggaagagacgacgagaggcttcttctgtcctcaaccaaaatgaaatt
ctctgcacaatcacctcttttccaagactgggttgccccggttttacgaagcctgaatat
ccgccaacaccttttgagagtggagcatcaaagtcactgtttttcccagatgaagccatt
aaccaccacccaagattcagcaccctcaccaggaacatacgtcacagacgaggagagaaa
gtcgcaatcaatgtaccaatattcaaagacaagtgcacgccatctcctttcgtggaaacg
tttcctgaagatgatggggagtcggcaagggcagctctgcctgaccacatctatatggac
tgcatgggctttgggatgggcaactgctgcctgcaggttactttccaagcttgcagcatc
gatgaggcaagatacctctatgatcaacttgcgacattctgcccgatagtgatggctctg
agcgcagcctctcccttctacagaggccacgtgtcagacatcgattgtcgctggggggtt
atttctgcctcagtggatgacaggacacaggaggaacgtggcctcaagcctttaaaaaac
gacaaatatagaatcttcaagtcaagatacgactccattgacagctacttgtctaactgc
ggcaacaagtataacgacattgatttgacgatcgatgaggacatctacaatcagctactg
ggtgcaggaattgacaagctgctggcccagcacattgctcacctctttatccgagatccg
ctgtgcgtctatgaggagaaattgcaacaggacgacgagaatgagtcggaccactttgag
aacatccagtcaaccaattggcagacgatgaggttcaaaccacctcctcccaactcggac
atcggctggagagttgagttccgcccgatggaggtgcagctcaccgatttcgagaacgct
gcttatgtggtctttgtcgtcctgctcaccagagtgattttgtcctacaaactggacttc
ctcatccctttatccaaggtggatgaaaacctaaaaatggcacagaagagaaacgcagtg
aaggatggaatgttctacttccgaaaggacatcttcaaaggatgcaacccaggcctggat
ggcacatcctcggcccagaacggtttggagacagacggagctaacgaggagtacaccctg
atgagcatcgacactatcatcaatggacaagcgagctga
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