Hippocampus comes (tiger tail seahorse): 109521188 Help Entry 109521188         CDS       T04969                                  Symbol obscn Name (RefSeq) obscurin isoform X1   KO K17531   obscurin-RhoGEF [EC:2.7.11.1] Organism hcq  Hippocampus comes (tiger tail seahorse) Pathway hcq04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:hcq00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     109521188 (obscn)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:hcq01001]     109521188 (obscn)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hcq04131]     109521188 (obscn) Enzymes [BR:hcq01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      109521188 (obscn) Protein kinases [BR:hcq01001]  Serine/threonine kinases: CAMK group   Trio family [OT]    109521188 (obscn) Membrane trafficking [BR:hcq04131]  Others   Rho GTPase associated proteins    Rho guanine nucleotide exchange factors (GEFs)     109521188 (obscn) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  I-set Ig_3 ig Ig_2 V-set Ig_5 Ig_4 Ig_6 Izumo-Ig fn3 V-set_CD47 RhoGEF C1-set Receptor_2B4 PH IQ Egh16-like IQ_SEC7_PH CDC48_2 Motif Other DBs NCBI-GeneID:  109521188 NCBI-ProteinID:  XP_019734406 LinkDB All DBs Position Unknown AA seq 6078 aa AA seqDB search MDQNLFGGAPRFLTRPKAFAVCVGKDATLSCTIVGNPTPLITWEKEKLKLTSGGRFKTVE DGDVYRLTIYDLALEDSGQYLCRAKNSVGEAYAAVTLKVALPAEMTPRAPVFMLKPTSAR VGLGDNAVFHCRVVAHPEANFDWEKDGRYLGETNRIKIISESDSSSLKIQSVRNLDSGTY ICTAQNTLGRAHAAAMLVVDAQGAHQFAAETHTSLLSHLQKRKEEMKKDIAVFRNEESAA SDKITDSLSSLSLEHEVRSSVLAKLPKGVFTRTCTVTEGKHAKLSCFVTGHPKPHIIWRK DGANISEGRRHVMYEDQAENFILKILYCKQDDNGFYTCNATNMAGQTYSAVLVTVKEPKV PFRRKLQDVAVQEKTSATLMCEVPLTGSRADWFMEETRLEQNAKYRMEEQGTLRRLTIHN VTTNDDGVYICEMKEGSRTVGELTVLGNITKKLPRKTVVPISDTVIFCVELEQPCPDVYW TRNGEKLKADSRISIACLHRQYTLTIRECQADDSGEVAFVAGDCKTSTRFSVTAARKHPP DPPVDAVVQNKTDSSITLQWSPPDSGRPVPIKSYIVERRKVGTQTWQRCNVGETILSTEI TISNFTEEATFQFRISAINDFGQSDYLEVPGSFYLEPTAEITKGLADSTAVSGEEFSISV ELSGVCSGFWSLNGRLLRSGGDYLITRSKNVHTLLIREATLDMNGTEVKFVGGGSQSSCI LAVKAPPVRFINKSDQQEVVFCSAQATAQMIAEVSDYDAQVVWMRNGREVKMGKKYESVT VDRRRTLRVHNVTEEDVGSYECVCADDKISMRLTLKDEPAKFLNKPRGPMGLLSSLKGDL ELSCDVSPASTAVTWKKDQLEIFEDQRTTIISKGTQRKLIIKNAKKSDEGHYCCETATDK ITFQVKIKETQAQPAFSNKELVQRELKVALSQKASLSCTVSDSKTEVKWYKDGKLLVSSR TLYTEVKGNHRQLVIEKIEKSDAGEYTCEAGGEKLVFKIIVPDSQAAFVNKETVQREVKA TLSERATLSCEVSDSTREVKWYKGGKLLVSGKTTRAETKGKIRQLVIDSVEKKDAGEYTC EAGEEKLVFQINVTEPPPAFVNKESVQKEVKANVSQKATLRCEVADSKIEVKWYKDGKLL GSSKTKRAESKGKSRQLVIDSVEKKDAGEYVCEAGAEKLIFKLQVADVPAKFQKKLVKDT CIIQASEQIVLTSELTSESSSGVRWFKDDVELKESTKYQMKKDGLSCTLIVMSTEFKDSG VYSCRTADDKLEFKVQVKDIAVNFVVRLKAVTVDLGADLNLTCELNQASGDVLWRRNGSE LKPGGRLRIKTDGVRRILIVTGMTKEDEGEYSCECKNDKTSAKVSSIAPRVVRLSSKLNN VAAMEGKDAIFKCTVTPADARVKWFHNNVPIAHGAKYKIEHGGNTHSVAVTCVTLKDAGE ISVDAEGKSCKATLQVQREPVTFKKKLENMTAEEQSEAKLEVELSKPSDEVHWMKNGVKL QTSVGVEVRVDGAKQALVFKSVTYADRGIYSCETLDDRTQAKLTVEMKKVELIKGLTETR THEKQTVSFEVELSQADVEGSWTRDGIRLKSEPNVRITALGKTHGLTLSNLTREDTGTIT FLAEGIRTSCKLIVTEPPVTISKPIVDISVAEKEKVTLECEVSRTNADVKWFKEDVQLKP GKNLSIHSLGRKRTLIINKCTPEDAGTYICQAADDSTCAKITVHARDVKIVKKLEDVEVM EKESAAFVCEVSHDEVECQWYKGSSKLRVSDNVKMRQEGRTYVLLFKSVSAADIGEIKFT AEKASSSAQLTVKELPVKFVKKLRDKIAIYKHRGHLECQVSRASAQVKWFKNKTELKPGQ KYEIKSDDVYRKLTIHNVDADDEDTYTCDASDDKTSCKLLVEEQSISIVREMSSVEVTEP FAAVFEVEISVELVKPPIWTLSKVALQENADVEMETEGTMHRLTFKKTKASMTGPVQFTA GKSKSLAQLTVKERPLEIAEPIKDVKAKEKSSAILTCKFSIPPKDKVQWFKEQVALAASD KYNIKQEATRAQLTIHGLTEEDSGEYRCQSGPAVTKGNLLVEVRDIKFTQHLADTEVDED SDAVFTCEVNYADEEARWLLNDKALFTNEVNTITHDGKVHKLTLKNLAPQDGGTITVYVR KVKESVTLKVKEKPALFLKSLDDVVGEEKGSITLACEASKPRVSPMWSKGGSPLKAGPKY ELLHTGKSLGLIIKDVTKDDAGEYTCDLGTEMSKAKVTVREIGIGITKWLKSAEVNEGET CAFECILSREITDECTWTLNGRTVASGGRFQMNSKGRKYMLTIKDVTPADAGDVIFSIKD LTSKASLTIEGKASTLSRDLENINVVRGENATFTCEVTQSTAIVKWTKEGKSIRKSQKYD IIKEDCVMKLVIHNVSSKDAGEYRCEVVGGATAKAKLDVKEPIHKFIKELKDTKADEKTS ATMQCETVQSPSAVTWLKGHTELKAGGRYEMSQKEAVLSLTVKHLQEDDTDIYTCDVGTA KSVAKLTVQALPATFKEKLKNRDATEGETVTLRCELSKPAANVHWRKGSETLTPGETYEI KQQEASCELRIRNVKTDHCGEYSCLCGDQKTSATLKVNALPPSFTVKLRSLEADEGSRVT LRCETSKPLVPVEWKKGAQLLTYGQKYQLKQQACEIELLINQTEPEDSGEYSCVCGEQTT MACVKIKALPVTFTKKLQPQEAEEGSSVTLRCETSKPGVPVEWKKERQVLKSGEKFQMKQ QACVNELHVSEVLPEDSGEYSCACGENNTAVVLTIKAQPVTFTVKLQPQDAEEGSRVALR CETSKPGVPVEWKKGRQVLKSGGKYQMKQQACVNELHISEALPEDSGEYSCVCGVNNTAA GLTIKAQPVTFTKKLQPQEAEEGSSVTLCCETSKPLVPVEWKKGRQVLKSGEKFQMKQQA CVNELHINEALPEDSGEYSCVCGENNTAARVTVKAQPVTFTKKLQSQEAEEDSSVTLCCE TSKPLVPVEWRKGRLVLKSGEKYQMKQRATVNELLICKAAEEDSGEYSCVCGENYTAANL TVIAQPVTFTKKLQSQEAEEGSSVTLRCETSKPGVSVEWKKGRQVLKSGETYLMKQEATV NELCIHEAAEEDSGEYSCVCGDNQTTASLKIRAVKPAASLPADKVESKRLGTQEMVKVVT LEETSEISQRQLVEQETRELRVEAQPVTFTKKLQSLEADEGSTVTLRCETSEPLVSVEWK KEAQVLTSGDKYQIKQQASANELLITQVVPEDSGDYSCVCGTQTTTTCVKIKAMKPPASL PAAKVETKIPEGKEKAEAKVTEATLVVAKDEQKKQEIHETVEVVTLHKTREMSEQQLVKQ EMQERRDEASPVLFKKTLDSQEGTEGEKVTLSCETSSPTCKVTWRKGSTLLSHGEKYSID QSAAIHTLVIHKLRPEDSGEYSCDTGDKKSAATVTVKEHVRILRELHDITVQTGQDAIFE VELSHAGVTSVEWWLADNLLQNNDLNQMSSEGRVHRLALKMVTTDESGDVAFVVGEEKSL ACLLVEEKPKVLIVKKPHNTAASEGETVTLACTISNPKVIVTWMRNNVVIKAGLKYDLKQ NGAFQQLCIHNVVPEDAGTYTCETVDDRCDVTLTVEATPAFFKKELENQDAIEGDDVTLR CELSKPGVCVEWRKGGAVLAPGKKCELWQEGCVHELRIWNLDPEDSGYYTCDAGDQLTTA SVTVQVKEIYILCGLKPVDVFVGEWATFSCQLSGQAPGKVQWWLDGTLLKSGPETEIGLS EGHIHTLTFKNLATDDSGTVMFKAGSLTSAAKLLVKDPTVEVVNDMEDLRVVENQPAEFI CQFSRPVKAEWKRDGQPLQPDGRRVVVEQDWTVSRLYISRVCAGDRGTYSCEAEGTRVVA SLHVEAKPINIVQGLENVETFDGGEALFECALSRPENKDCLWLLDDKPVKESPNAEIVSF ESGRRHLLLLKELRVSDSCTVTFRAGTTSTSAHLAVKGWQLGVAKHLEDVVAAVGERVEF GVELTEPVLASEIVWYANGVELKPGQLWITRNDGCRYRLILRQAPLMAQQEITFAARDAL SMAKLSIIAVPDPPEDPEVLSKTKESVTLSWFTPLHDGGSPILGYKVEMRLAESALWLPC HSTPVSNTEFVVGNLIQGTGYRFRVAAINRAGTGESVELPQTVQLETEVKEIESEQLGQP SLPPEAAEEGDLHDLWEASAKKRRMSREPTLDSITEHPEDDGKGGPKKTEQKESSDSEKE SISKESEQTKKQTESELHTSSEESHSDGSSLVSYLKKNSQLQSSSTVETSDDRTLATERF FKHFQMTDQKTTTVQRTETKQASTPETEILEISKEDEPELREAAIKIQAAFKGYKARKDM RPVFKEVFKDQTKEPNGTIHLECVAEGKPDKVRWLKDGEPLSDGKHHHIDIYNDGTCSLV ITAITTKDTGVYTCEVNNKFGVISHSAKVTVGTVRESCGRRPLTVGYSADSEPDSSSGSE MDESLRQASRRLRRLLRTRLPPDVEEEPFISADEGELCPPDPHSYREDDRYIYIRFDTWS EAEVASKRFHEMFTIHGVPVETSILDAGHLKVELRIRKMEFTQDGTETPTQEKQPPVLLS GAAAAPVFLTELQNQDVPEGYPVSFDCVVIGKPSPAVRWYKDGKVLEENDHYMINEDQEG CHQLIITAVLPSDMGVYRCTAENSSGIAATRAELRVDMSCSSDYDTAADATETSSYISAK GYLSSRETETFESVTEDDQLPQVVEELHDVHVSPGSPMAKMQLRVKGFPKPRVYWFKDGH PLHGSEKILVLAQQDLHSLEILEVKKEDMAEYSAYISNAAGSAYSSARLIVLNPGEIIPQ DAKDSRESLVPPRFLEKFCNRKVKQGTSITLSVKVEGSPTPVVSWLKEESVEEVLWIKPD TKGYKVASSGRQHSLILMDVGTEYTGAYTCIATNKAGQSICTAHLEVDDTPPQKKETKAS DVLGITVSPPEEAAKRGKESKMSYFGEVGSEEFLMKLTSQITEMVSAKITQDSTQNQEVL QWMKSWPKTTSSLRVPGADSDDDTKTPSASPHHGRSRPPSLVADSSSESDEGDARGEMFD IYVATANYDPIVASKESVSLKEGQYVEVLDSAHPLKWLVRTKPTKTTASRQGWVSPAYLD KKFKLSADSGDLPETSVEEVSEGEYKKKLFQLIHDIINGESEFVKEIDFFTGHHLRHADS PDAPSDVSGQREVIFRNINDLKDFHARAFLPKLSDCETDDDVAMCFLKNKEGFEKYLQYL VGQSQAESAISDKTVHRFFKEYTEKEQANADPADPPIRSINAYLLQPLDRIQKYKVFLKE LIRNKARNGQNCCLLEEAYAMVSALPQRSENTHHVSLIENYPATLEALGEPLRQGPFQVW EGAPGIRTSSRGHHRHVFLFKNYCIICKSKRDSNTDSQTYVFKNMMKLNNIDVNDTVEGD DRAFEIWHEREDSVRKYTLQARTVTMKNSWLRDFRELQQRYSMPAWSPPDFVEILANCTA ELGQTVKLACKATGVPKPAITWYKDGRIVEADPHHIIIEDPDGSCTLILDNMTAEDSGQY MCFATSSAGNASTLGKITVQVPPRFVNKLRNAICVSGEDAQFTCVIQSAPSPKIRWFKDG RLLSDQEKYETYSELRSGVLVLVIKNVTDRDLGHYECELSNRLGSARCAADLVPLSAASS GEQAIVLEVTEQETKIPKKTIIIEETITTVVKNPRMRRHKSPGMTGTGAHRLEMTASETS TSRTRRMAAAPRKSAVPTYYVTEAEGAEGASSIVAESKPNWVEVEEVIEYKVNKSPRPSR RRGVSPAILDRSAAPSRPKRSPAENPNANNSNNNLVELGGSAWEDEATPSGSGDPFEISS VLTTAGEAREDPEDLQIVILEPDDDNDEDLYGKQEAKTLTRGSHVLALEDLEDYVPQEGG SDGSTSYGPVEKPCEISVLQREVGGTAVGHPVLLNVGRPVAAPRHRSGFFSRCREHLAGN VFSSNAPQGSSTQSERRVPIQVSHAKLEVKPSYCSEVQRVGGGQRSFKTKLSTQMSGYTS VGNPVTLQISDKQQPQNQ NT seq 18237 nt NT seq  +upstreamnt  +downstreamnt atggatcaaaatttgtttggaggggcccccaggttcctcacccggcccaaagcgttcgcc gtgtgcgtcggcaaggacgccacgctgagctgcaccattgttggcaaccccacaccactt atcacctgggagaaagaaaagctgaaactgacatccgggggccgcttcaagactgtggaa gatggggatgtctaccgtctgaccatctatgacttagcgctggaagacagcggtcagtac ctgtgcagggccaagaacagtgtcggcgaggcctacgcagccgtgaccctcaaagtggcc ctcccagcagagatgactccaagagcccccgttttcatgctcaagcccacatcagcacgt gtgggtttgggggacaatgccgtgttccactgcagagtagtcgctcaccccgaggccaac ttcgactgggagaaggacggacgctacctgggcgagaccaaccgcatcaagatcatttcg gagagcgacagcagcagcttaaagatccagagcgtgcgcaacctggacagcggcacgtac atctgcacggcccagaacactttgggccgggcgcacgccgccgccatgctggtggtggat gcccagggtgcccaccaattcgcagcggaaacccacacctccctcctttctcacctccag aaacgtaaagaagaaatgaagaaggacatagctgtctttcgtaacgaggaaagcgccgcc tcagataaaatcacagacagtctgagttccctgagtctggagcatgaggtgaggtcgtcg gtactggcaaaactgcccaagggtgtgttcacccgcacctgcacagtgacggagggaaag cacgccaaactcagctgcttcgtgacgggtcaccccaagcctcacattatctggagaaag gacggagcaaatatcagcgagggccgccgccacgtcatgtatgaagaccaggcagagaac ttcatcctcaagatcctttactgcaaacaggacgacaacggtttctacacctgcaatgcc accaatatggctggtcagacctacagtgctgtgctggtaacagtcaaggagccaaaggtg ccgttcaggaggaagcttcaagatgtggcggtccaagagaaaacgtcggccacgttgatg tgcgaggtgccgctgactggcagcagggctgactggttcatggaggaaacgcgcctggag caaaacgctaagtatcgcatggaggaacaaggcaccctgcgtcggctcaccatacacaac gtgaccaccaacgatgacggcgtttacatctgtgagatgaaggagggcagccgcacagtg ggcgagctcaccgtcctgggcaacattacaaagaagcttccgcggaagacggtcgttccc atcagcgacaccgtcatcttctgcgtggagctggagcagccctgtccggacgtctactgg acccgcaacggcgaaaagctgaaggcggattcccggatttccatcgcttgcctgcaccgc cagtacacgctgaccattcgggagtgtcaggcggatgattcaggagaagtggcctttgtg gctggagactgcaagacgtccactcgattctctgtcaccgcggcaaggaagcatcctccc gatcccccggtcgatgctgtggtgcaaaacaagacggactcatccatcaccctgcagtgg tctcctccagacagtggccgccccgtgcccatcaagagttacattgtagagaggaggaag gttggcactcagacctggcagaggtgcaacgttggagaaacgattttgtcaacggagatc acaatctctaacttcacagaggaagccactttccaattccgtatatctgccatcaatgac tttggtcagagtgactacctggaggtgcctggaagcttctaccttgaacccactgctgaa atcacgaaaggccttgcggacagcaccgcagtttccggtgaagagttctccatttcggtg gagctctcaggcgtttgctcgggcttctggtctctaaatggccgcctgctgcgaagtggt ggcgactacctcatcacccgttccaagaacgtacacacgctgctcatccgagaagcgact ctggacatgaacggaacagaagtcaaatttgtgggcggaggctcacagagcagttgcatc ctagctgtcaaggcgccgcctgtccggttcatcaataagtcagatcagcaagaggtggtg ttctgcagcgcccaagccactgctcagatgatagctgaggtgtcggattacgatgcgcag gtggtttggatgagaaatggacgggaggtaaaaatgggcaagaagtatgaatcggtgact gtggaccgcaggaggaccttgagggtacacaacgtgacagaggaagacgtgggcagttac gagtgtgtttgcgctgatgacaagatttccatgcggctcactcttaaagatgaacctgcc aagttcctaaataaacccagaggtccaatgggcctgttatcctcactcaaaggagatctc gagctgagctgcgacgtttctcctgctagcacggcggtcacatggaaaaaagaccagctg gagatcttcgaggaccaaagaactaccatcatctctaaaggtacccaaaggaaactcatc atcaaaaatgcaaaaaaaagcgatgagggtcattactgctgcgagacggccaccgacaaa atcacattccaggttaagattaaagaaactcaagcccagcctgccttctccaacaaggaa ttggtgcagagggaattaaaagtggctctctcccaaaaagccagtctcagttgcacagtt tcagacagcaagacagaggtgaaatggtacaaagacggcaagctgctcgtctccagtcga actctttacacggaagtcaaaggcaatcaccgccaactggtgattgaaaaaattgagaag agtgatgctggagaatatacttgcgaggctggaggagagaagctggtcttcaaaattatt gtgcctgactcccaggcggccttcgttaacaaagaaacagtccagagggaggtgaaagcc actctctccgagagagccactctaagctgtgaagtgtctgattcaaccagggaagtcaaa tggtacaagggcgggaagctgctggtctctggtaagacaacacgtgccgaaacaaagggg aagattcgccagctggtgatcgatagcgtggagaagaaggatgccggggaatacacgtgt gaagccggggaggagaagctcgtctttcagatcaatgtgactgagcctccaccagccttc gtcaacaaagaatctgtccaaaaggaggtgaaagcaaatgtatctcaaaaagccactctc cgctgtgaggttgctgactccaagatagaggtgaaatggtacaaggacgggaaactgctg ggcagtagtaagacaaaacgtgcagagtccaaggggaaaagtcgccagctggtaatcgac agtgtggagaaaaaggatgcgggagagtacgtctgcgaagccggtgctgagaagttgatc ttcaagctccaggtggcagatgtgcctgccaagttccagaagaagctcgtcaaggacaca tgcatcattcaggccagcgagcagattgttttgaccagcgagctgacttcagagagcagc agcggcgtgaggtggtttaaagatgacgtggagctcaaggagagcaccaagtaccaaatg aaaaaagatggcctctcttgcacactcatcgtcatgtccactgaattcaaagacagcggt gtgtactcctgtcggactgctgatgataaactggagttcaaagtccaggtcaaagacata gctgttaactttgttgtccggttgaaagccgtcacggtcgacttgggggccgatttaaat ctaacgtgtgagttgaaccaagcttcaggcgatgttctatggcggcgcaacggttctgag cttaaacctggaggcaggttgcgcatcaagacagacggcgtaaggcgaatcctcatagtg actggcatgacgaaggaagatgaaggcgaatacagctgtgaatgtaaaaatgacaagacc tctgccaaagtctcctcaatagccccccgagttgtgagactgtcttccaagctgaacaac gtggccgcaatggagggcaaagatgccatattcaagtgcaccgtcaccccggcggacgca cgcgtcaaatggttccacaacaatgttcctatcgctcatggcgccaagtataagattgag catggtggcaacacccactcggtcgccgtcacttgtgtcaccctgaaggatgcgggggag atcagcgtggacgccgaagggaaaagctgcaaggcgacgcttcaagtgcaacgtgagccg gtgacattcaagaagaagctggagaatatgacagcggaggagcagagcgaggcaaagctc gaggtggagctgagcaagccgtcagacgaagtgcactggatgaagaacggcgtcaagttg cagacttcagtgggtgtggaggtccgggtggatggcgctaagcaggcgctggtcttcaag agtgtgacttatgccgaccgcggcatctactcgtgcgaaacccttgatgacagaacccag gccaagctcaccgtcgagatgaagaaagttgagctgatcaaaggtctcacggaaaccagg acacacgagaaacagacggtaagcttcgaggtggagctcagccaggctgatgtcgaaggc tcgtggacccgggacggcatcaggttgaaatcagagcccaatgtccgcatcacagctctg ggaaaaacgcacggccttaccttgtcaaatctgacgagagaggacacgggaaccatcacc ttcctggcggaagggatccggacttcctgcaaactcattgttacagaaccccctgttacg atctcaaagcccattgtcgacatcagcgttgctgagaaggagaaggtcactttggagtgt gaagtatcaagaacaaatgcagatgtaaaatggttcaaggaagatgtacagctgaaacca gggaaaaatttaagcattcattctttgggacgaaaacgcaccttgatcatcaacaaatgc acccccgaagatgcaggcacttacatctgtcaagctgccgacgacagcacctgcgccaag atcaccgttcacgccagagatgttaagattgtgaagaagctggaggatgtggaggtgatg gagaaggagagcgctgcatttgtttgcgaggtttcacacgacgaagtggagtgccagtgg tacaagggaagctccaaacttagagtcagcgacaacgtcaagatgagacaagaaggcagg acctatgtgttgctgtttaaaagtgtgtctgcagcagatataggtgagattaaatttaca gcagagaaggcctcgtcatctgcacaactgacggtgaaagagctgcccgtcaagtttgtg aagaaactccgagataagatagccatttacaagcaccgtggccacctggagtgccaagtg tcccgcgccagtgcccaagtcaagtggttcaaaaacaagacagagttgaaacccggacag aagtatgagatcaaaagtgacgacgtgtaccggaagctcaccatccacaacgtggacgcc gacgacgaagacacgtacacgtgcgacgcctctgatgacaagacatcctgtaaactgctt gtggaagagcagtccataagcattgtgcgggagatgagttccgtggaggtgacggaacct ttcgccgctgtcttcgaagttgagatcagcgtggaactggtgaaaccgcccatttggact ctcagcaaagtcgccctgcaggagaacgccgatgttgagatggagacagagggcaccatg catcgtctcactttcaaaaagaccaaagcatccatgacgggccccgtgcagttcacggct ggcaagagcaagtcacttgcccagcttacagtcaaagagcgtccccttgagattgcagag cccatcaaagacgtgaaggccaaggagaaaagctctgccattctcacttgtaaattctct atcccgccaaaagacaaagtgcagtggtttaaagaacaggtagcactggctgcatcagac aaatataacatcaagcaagaagctaccagggctcaactcaccattcatgggctgactgaa gaggacagtggcgagtaccgctgtcagtctggacctgctgtgacaaaaggaaatcttcta gttgaagtgcgtgacataaaattcacccagcacctggctgacactgaagtggacgaagac agcgacgcagtgttcacatgtgaggtcaactatgccgacgaggaggcccggtggctcctg aatgacaaggcgctcttcaccaatgaagtcaacaccataacccatgacgggaaagtgcat aaactcacacttaagaacctggcacctcaagatggcggtactatcacagtttacgtccgc aaggtgaaggaatctgtcacgcttaaggttaaagaaaagcctgcccttttcctcaagtct ctggatgacgtcgtcggtgaggagaaaggttccatcactctggcttgtgaggcatccaaa cccagagtctctcccatgtggagtaaaggaggcagcccgttgaaagctggacccaaatat gagctccttcacacgggcaaatctttggggctgatcatcaaggatgtgaccaaagacgac gcgggggagtatacttgcgatctgggaactgagatgtccaaagcaaaggtcactgtaaga gaaattggcatcgggatcacaaaatggctgaagtcagctgaggtgaacgagggtgagacg tgcgctttcgagtgcatcttgtctcgggagatcaccgacgagtgcacctggactcttaac ggccgaaccgttgcaagcggaggccgctttcaaatgaacagcaaaggacggaagtacatg ctgaccatcaaggacgtcacccctgctgatgccggagacgtcatcttcagcattaaggat ctgacctccaaagcatcactgactattgaaggaaaagcgtcaacactctcaagggacctg gagaacatcaatgtggttcggggggaaaatgccacttttacctgcgaggtgacacaatca accgccattgtcaaatggacaaaggagggcaaatccataaggaagagccagaagtacgac atcatcaaggaagactgcgtgatgaagctggtcatccacaacgtctccagtaaagacgct ggggagtacagatgtgaggttgtcggaggggcaaccgcaaaggccaagcttgacgtgaaa gagccaatccataagttcatcaaagaactgaaggacaccaaagcggatgagaagacctct gcgacgatgcagtgcgagacggttcaaagcccgtctgcggttacctggcttaaagggcac acggagctcaaggctggcggtcgatacgagatgagccagaaggaagcagtcttatctctc accgtcaaacacctccaggaagacgacactgacatctacacctgcgatgtgggcacagcc aagagcgtggccaagctgactgttcaggctctgcctgccactttcaaagaaaagctcaag aatcgagatgcaacggaaggagaaactgtgacacttcgctgtgagctatcgaagcctgca gccaacgttcactggaggaaaggctctgaaactctcactcctggagagacgtatgagata aagcagcaagaggcatcttgtgagcttcgcattaggaatgtcaaaacggaccattgcggg gaatactcttgtctatgtggggaccagaagacatcggcgactctcaaagtgaacgcatta ccgccatccttcacggtgaagctgcggagtctggaggccgacgaaggatccagggttacc ctacgctgtgagacctcgaaacctttagtccctgttgagtggaaaaagggtgcacagctg ctcacgtatggacaaaaataccagctgaagcagcaggcttgtgagattgagctcctcatc aaccagaccgagcccgaggacagcggagagtacagctgtgtgtgtggggagcagacaacc atggcctgtgtcaagatcaaggccttaccggtgaccttcacaaagaagctgcagcctcaa gaggccgaagagggatccagcgttacactacgctgtgagacatcgaaacccggagtgcca gtggagtggaaaaaagaaagacaagtgctaaagtctggagaaaagttccagatgaagcag caagcgtgtgtcaatgaactccatgtcagtgaagtactgccagaagacagcggggagtac agctgcgcgtgtggggagaacaacactgcagttgtcctcactattaaagcccaaccggtg accttcacggtgaagctgcagcctcaagacgccgaagagggctccagggttgcgctacgc tgcgagacatcgaaacctggagtcccggtggagtggaagaaaggaagacaagtgctgaag tctggaggaaagtaccagatgaagcagcaggcgtgtgtcaatgaactccacatcagtgaa gcgctgccagaagacagcggggagtacagctgtgtgtgtggggtgaacaacactgcagct ggcctcaccattaaagcacaaccggtgaccttcacaaagaagctgcagcctcaagaggcc gaagagggatccagtgtcacgctctgctgcgagacgtctaaacctttagttccagtggag tggaagaagggaagacaagttctcaagtcgggagaaaagttccagatgaagcagcaagcg tgcgtcaatgaactccacatcaatgaagcgctgccagaagacagcggggagtacagctgc gtgtgtggtgagaacaacactgcagctagagtcaccgttaaagcccaaccagtgaccttc acaaaaaagctgcagagtcaagaagccgaagaggattccagtgttactctctgctgcgag acgtcaaaacctttagtcccagtcgagtggaggaagggaagactcgttctgaagtcggga gaaaagtaccagatgaagcagcgagcgactgtgaatgaactcttgatttgtaaagcagca gaggaagacagtggagagtacagctgcgtgtgtggggagaactatactgcagctaacctc actgttatagcccaaccggtgaccttcacaaagaagctgcaaagtcaggaggcggaagag ggatccagtgtgactcttcgctgtgagacgtccaaaccaggagtctcagtggagtggaag aagggaagacaggtcctcaagtctggagaaacgtacctgatgaaacaggaggcgactgtc aatgaactatgtattcatgaagcagcggaagaagacagcggggagtacagctgcgtgtgc ggcgacaatcaaacgacagccagtctcaaaatcagagccgtgaagccggcagcttccctc ccggctgataaagtggaatcaaagaggcttggaactcaagaaatggtgaaagtggtgaca ctggaagagaccagcgagatctctcaacggcaactcgtggaacaagagactcgcgagctt cgagttgaagcccaaccagtgaccttcacaaagaaactgcaaagtctggaggccgacgag ggatcgacggttactcttcgatgtgagacttcggagcctttagtctcagtggaatggaag aaggaagcgcaggtcctgacgtctggagataagtaccagataaagcagcaagcgtctgcg aatgaactgcttatcacccaagtggtgcctgaagacagtggagactacagctgtgtgtgt ggaacgcagacaaccacgacttgtgtcaagatcaaggccatgaagccaccagcttccctc cctgctgctaaagtggaaactaaaataccggaaggtaaagaaaaagcggaagccaaagtg actgaagctacattggtggttgctaaagatgagcagaagaagcaggagatacatgaaaca gtcgaagttgtgacactgcacaagaccagagagatgtctgaacagcagcttgtgaaacaa gagatgcaggagcgcagagatgaagcctcgcctgttttattcaagaagaccctggacagc caagagggcaccgagggtgaaaaagtcactttgtcttgtgagacatccagccccacctgc aaggtgacttggcggaagggctcaactctgctcagccacggggagaaatacagcatagac cagagcgctgccattcacactcttgtcattcacaagctgagaccggaggatagtggggag tacagctgcgacacgggtgacaagaaaagcgctgctactgtcactgtcaaagaacacgtg cgtatcctgcgggaactgcacgacattaccgtgcaaacggggcaggacgctatcttcgag gtggagttgtctcacgccggtgtgaccagtgtggagtggtggctggcagacaacctcctc cagaacaatgacctgaaccagatgagtagcgagggccgagtgcatcgcttggccctgaag atggtgaccactgacgaatcgggagatgtcgcctttgttgtgggtgaagaaaagagcctt gcttgtttgctggtggaagagaaaccaaaagtgctcattgtcaagaagccgcataacacg gcagcatcggagggggaaaccgtcaccctggcctgcaccatctccaaccccaaggtgatc gtgacctggatgagaaacaatgtggtcatcaaagcaggtctcaagtacgatctgaagcag aacggagccttccagcagctttgcattcacaatgtggtgcccgaagacgcggggacgtac acctgcgagaccgtagatgatcggtgtgacgtcaccctaactgtggaagctaccccagcg ttctttaagaaggagctggagaaccaggatgccatcgagggtgacgacgttaccctccgc tgcgaactatccaagccaggggtctgcgtggagtggaggaaaggaggtgcagttcttgcg cctggtaagaaatgtgaactctggcaggaagggtgcgttcacgagctccgtatatggaac ctggatccggaagacagtggttattacacctgtgacgcaggagatcaactgaccactgcg tctgtgacagtgcaagtgaaagagatctacattttgtgcggtcttaagcccgtggatgtg tttgttggggaatgggcaacattctcttgtcagctgtccggccaggcgcccggcaaagtg cagtggtggttggacggcactttgctgaagagcggccccgagactgagatagggctgagt gagggccacatccacacactcacctttaagaacctggccacagatgactcgggcactgtc atgttcaaagctggcagtttaacctcagcagccaagctccttgtcaaagatcccacagtt gaagtggtgaacgacatggaggaccttagggtggtcgagaaccaaccggccgagttcatc tgccagttctcgaggccggtgaaggccgagtggaagcgagacgggcagccgttgcagcct gatggccgcagggtggtagtggagcaggactggactgtgtctcgcttgtacattagccgc gtgtgtgccggagacaggggcacatactcctgtgaggcagaggggacccgtgtggttgct tcgcttcatgtggaagccaaacccatcaacatagtccaaggcctggagaacgtggaaacc tttgacggaggagaagctttgtttgagtgtgccttgtctcgtccggagaacaaagactgc ctgtggctcctggatgacaaaccggtgaaggaatcacccaatgctgagattgtgtccttt gagagcggccgtcgtcacctgctcctcctcaaagagctgcgcgttagtgacagctgcaca gtcaccttcagggcgggcacgacgtccacgtctgcccaccttgctgtcaagggctggcag ctgggcgtggcaaagcatctggaggacgtggtggccgccgttggtgagagggtggaattt ggtgtggagctgactgagcccgtgctcgcgtcggaaatcgtttggtatgccaacggagtg gagctcaagcccggccaactgtggatcaccaggaacgacggatgccgctatcgcctcatc ctgaggcaggcaccactcatggctcaacaggaaataacctttgcagcacgcgacgctctc tctatggccaagctctccattatcgctgtaccagacccaccggaggaccccgaagtcctc agcaagaccaaagaatcggtcaccctttcctggttcactcccctacatgacggaggaagt cccattctgggctacaaggtggagatgaggctggcagaaagcgctctgtggcttccgtgc cactccactcccgtgagcaacaccgagtttgtggtgggaaatctcatccagggcaccggc tacaggtttcgagtggcagccatcaacagagccggtacaggggagtctgttgagcttcct cagactgtgcagcttgaaacggaggtcaaagaaattgagtcggagcaactaggacagccc agtcttcctccggaggctgctgaagaaggagacctccatgatctgtgggaggcctcggcc aagaaaaggcgcatgagtcgcgaacctactctggactccatcactgaacacccagaggac gatgggaaaggcggcccaaagaaaacggagcagaaggagagcagcgattcagagaaggaa tcaatatcaaaagagagcgagcagaccaagaaacagaccgagtctgaattgcacaccagc tctgaggagtcccattctgatgggtcttcgcttgtgtcctaccttaagaagaacagtcag cttcagtcttcatccacggttgagacctccgatgaccggacactagccaccgagcgcttc tttaaacactttcagatgaccgaccagaaaacgacgacagttcagcggaccgaaacaaag caggcatcaacaccggaaactgagatcctggagatcagcaaggaagacgaacctgagctc agggaagctgccatcaagatccaagctgccttcaagggctacaaggcgcgcaaggacatg cggccggttttcaaggaggttttcaaagaccagaccaaagagccgaatggcaccatacat ctggagtgtgtggcagaaggtaaacccgataaggtgcgttggctgaaggacggagagccg ctgtcggacggcaaacaccaccacatcgacatctacaacgacggcacttgttccttggtc attactgccatcaccaccaaagacacgggcgtgtacacgtgcgaggtcaacaataagttt ggcgtcatctctcacagtgcaaaggttacggtgggaaccgtgagagaatcatgcggccgg cggccgctgacagttggctacagcgccgacagtgagccagacagctcgtcgggcagcgag atggacgagtcgctgaggcaggcgagcagacgcctccgccggttgctacgtacgcgcctc ccgccggatgtggaggaggaacctttcatcagcgcagatgaaggagaactctgccctccg gatcctcactcttaccgtgaggatgacaggtacatttacatccgcttcgacacgtggtca gaggcggaggtggcgtccaagaggttccacgagatgtttaccatccacggagtcccagtg gaaaccagcatcctggacgccggacatctcaaagtggagctgcggattaggaagatggag ttcacacaggatggcacagaaacacccactcaagaaaaacaacctcctgtgttattgtct ggagctgctgccgctcccgtcttcttgacagagttacaaaatcaggacgtgcccgaaggc tatccggtcagcttcgactgcgtggtgatcggcaagccttcgcccgccgtgcgctggtac aaagatggcaaagtgctggaggagaatgaccactacatgatcaacgaggaccaggaaggc tgccatcagctcatcatcactgccgtgctgccgtccgacatgggagtctaccgttgcacg gcggaaaacagcagcggcattgcggccaccagggccgaactcagggttgacatgtcctgc agctcagattatgacactgctgctgatgccactgaaacctcgtcttacatcagtgccaaa ggctacttgtccagcagggagaccgagacctttgagtccgtgacggaagatgatcagttg cctcaagttgtggaggaacttcatgatgttcacgtgagcccaggttcaccaatggcgaag atgcaactcagggtcaaaggtttccccaaaccgagagtgtattggttcaaagacggccat cccctgcacggttccgaaaagattttggtgttagcgcagcaagaccttcacagtctcgag atcctggaggtgaagaaagaggatatggcggaatactcggcctacatcagtaacgcggct ggttctgcatactcttctgcccggctcattgttctaaatccaggggagattatacctcaa gatgcgaaagactcccgggagtctctggtgcctccgcgtttccttgaaaaattctgcaac aggaaagtgaaacaaggaaccagcatcacattatccgtcaaagtcgaaggatctcccact ccagtggtctcgtggctaaaggaggagtcggtggaggaggtgctgtggatcaagcctgat accaaaggatacaaagtagcaagctccggccgccaacacagtctcatcttaatggatgtt ggaaccgagtacaccggcgcctacacctgcattgccaccaataaggcgggacagtccatt tgtactgcccaccttgaggtggatgacactccaccacaaaagaaagagaccaaggcttca gatgttctcgggattactgtcagtccaccagaagaagctgcaaagaggggaaaggagagt aaaatgtcctactttggagaagttggttccgaagaattcctcatgaaactcacctcccag atcactgaaatggtatcggccaagattacgcaagacagcacacagaatcaggaagtgctc cagtggatgaaatcctggcccaaaacgaccagctcattgcgcgtaccaggtgcagacagt gacgacgacaccaagaccccttcggcttctcctcaccacggtcgctcccgtcccccctcc ctcgtggctgactcctcgtctgagtccgatgaaggagatgccaggggagagatgttcgac atctacgtggcgacggccaactacgaccccatcgtggccagcaaagaatccgtctccctg aaggagggacagtatgtggaggtgttggattcggcccacccgctcaaatggctcgtgcgg accaaacccaccaagacgacggcatcccgccaaggctgggtgtcgcctgcctatctggac aaaaagttcaaactatctgctgattcgggtgaccttcctgagacaagcgtagaggaggtg tctgagggagaatacaagaagaagttattccagttgattcatgacatcataaacggtgaa tcagagttcgtcaaagagatagacttcttcacgggtcatcacctgaggcacgccgactct cctgatgcaccgagtgatgtcagcggccagagggaagtcatctttaggaacatcaacgac ttgaaggacttccatgccagggcgttcctgccaaaactgagcgattgtgagacggatgat gatgtcgccatgtgcttcctgaagaataaggaaggctttgagaagtacctccagtatctt gtaggtcagagccaggctgaaagtgccatcagtgacaaaacggtccaccgcttcttcaag gagtacaccgaaaaggagcaagccaatgcagacccagctgacccgcctatacgcagcatc aacgcctacctgctacaacctctggacaggattcagaagtacaaggtcttcctcaaggag ctcattcgaaacaaggccagaaatggccagaactgctgcctgctggaagaagcgtacgcc atggtgtcggcactgccgcaacgctctgagaatacccaccacgtctccttgattgagaac taccccgccacccttgaagcgttaggggagcctcttagacagggacccttccaagtttgg gagggggctcctggaataaggacgtcctctcgaggtcaccaccgccacgtcttcctcttt aagaactactgcatcatctgcaaatccaagagagacagcaacaccgattcgcaaacatac gtctttaagaacatgatgaagctgaacaacattgacgtgaatgacacggtggagggtgac gaccgcgcttttgagatctggcacgaacgcgaagattcggtgaggaagtacactttgcag gcccgaaccgtgaccatgaaaaactcgtggctgagagacttccgagaacttcagcagaga tacagcatgcccgcctggagtcctcctgactttgtcgaaatactggcaaactgcacagcc gagcttgggcagactgttaaactggcgtgcaaggccacgggagttcccaaacctgccatc acctggtacaaggatggacgcatagttgaggcagaccctcatcacataattatcgaggac cccgacggctcctgcacactcatactggataacatgacagccgaggattcgggccagtac atgtgctttgccacgagctcagccggcaacgccagcacgctgggcaagatcaccgtacag gtgcctccgcggtttgtgaacaaattgaggaatgcgatttgtgtctccggtgaagacgct cagttcacctgcgtcatccagagtgctcccagtcccaaaatcagatggttcaaggacggc cgcctgctgagcgaccaagaaaagtatgagacctacagtgagctccgcagcggagttttg gtcttggtgatcaaaaatgtgacggatcgagacctgggacactacgagtgtgagttgtcc aaccgtctgggcagtgccaggtgtgccgctgacttagttcctctatcggccgctagcagt ggtgagcaggccattgttcttgaagttaccgagcaggaaacaaaaataccaaagaaaacc atcatcattgaggagacgatcaccacagtggtgaagaatccaagaatgaggaggcacaag tcccctggcatgactggcactggagcccaccgcttggagatgaccgcctcagagacctcc accagcaggaccaggcggatggccgccgctcccaggaaaagcgcggtgccaacctactat gtcacagaagctgagggtgcggagggtgccagttctattgtcgctgagagcaagcccaat tgggttgaggtggaggaggtgatcgagtacaaggtcaataaatctcccaggccatccagg aggaggggtgtgtcgccggccatcttggaccgctccgccgctccttccagacccaaaaga tcacccgcagagaacccgaatgcaaacaattccaacaacaatctggtggagctgggaggc agcgcctgggaggatgaggcgactccgtctggttcaggagatccctttgagatctcgtct gttcttaccacggctggggaggctcgtgaagacccggaggatctgcaaatcgtcatcttg gaacccgatgatgataatgatgaagacctttatggaaagcaggaagcaaagacactaaca cgtggaagtcatgttctagcactggaagacttggaggattacgtcccacaggaaggagga tctgacggttcgaccagctacggtcctgtcgagaagccctgtgagatctccgtgctccag agggaggttggcggcaccgccgtgggacatccggtgctcctcaacgtgggacgtcccgtg gcggctccgaggcatagaagcggatttttctctcgctgcagagaacatctagccggcaat gttttctcatctaatgcgccacaaggaagcagtacccagtcggaaaggcgtgtccccatt caagtgagccacgccaagctggaggtgaagccttcgtactgctccgaggtgcagagggtg ggaggagggcagcggagctttaaaaccaaattatcaacgcagatgtccggctatacatcc gtgggaaaccctgtcacacttcaaatcagcgacaaacaacaaccccaaaaccagtag

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