Heterocephalus glaber (naked mole-rat): 101698346 Help Entry 101698346         CDS       T02812                                  Symbol Prkcg Name (RefSeq) protein kinase C gamma   KO K19663   classical protein kinase C gamma type [EC:2.7.11.13] Organism hgl  Heterocephalus glaber (naked mole-rat) Pathway hgl01521   EGFR tyrosine kinase inhibitor resistance hgl04010   MAPK signaling pathway hgl04012   ErbB signaling pathway hgl04014   Ras signaling pathway hgl04015   Rap1 signaling pathway hgl04020   Calcium signaling pathway hgl04066   HIF-1 signaling pathway hgl04070   Phosphatidylinositol signaling system hgl04071   Sphingolipid signaling pathway hgl04150   mTOR signaling pathway hgl04270   Vascular smooth muscle contraction hgl04310   Wnt signaling pathway hgl04370   VEGF signaling pathway hgl04510   Focal adhesion hgl04540   Gap junction hgl04613   Neutrophil extracellular trap formation hgl04650   Natural killer cell mediated cytotoxicity hgl04666   Fc gamma R-mediated phagocytosis hgl04670   Leukocyte transendothelial migration hgl04713   Circadian entrainment hgl04720   Long-term potentiation hgl04723   Retrograde endocannabinoid signaling hgl04724   Glutamatergic synapse hgl04725   Cholinergic synapse hgl04726   Serotonergic synapse hgl04727   GABAergic synapse hgl04728   Dopaminergic synapse hgl04730   Long-term depression hgl04750   Inflammatory mediator regulation of TRP channels hgl04911   Insulin secretion hgl04916   Melanogenesis hgl04918   Thyroid hormone synthesis hgl04919   Thyroid hormone signaling pathway hgl04921   Oxytocin signaling pathway hgl04925   Aldosterone synthesis and secretion hgl04928   Parathyroid hormone synthesis, secretion and action hgl04929   GnRH secretion hgl04935   Growth hormone synthesis, secretion and action hgl04960   Aldosterone-regulated sodium reabsorption hgl04961   Endocrine and other factor-regulated calcium reabsorption hgl04970   Salivary secretion hgl04971   Gastric acid secretion hgl04972   Pancreatic secretion hgl05017   Spinocerebellar ataxia hgl05022   Pathways of neurodegeneration - multiple diseases hgl05031   Amphetamine addiction hgl05032   Morphine addiction hgl05143   African trypanosomiasis hgl05146   Amoebiasis hgl05161   Hepatitis B hgl05163   Human cytomegalovirus infection hgl05170   Human immunodeficiency virus 1 infection hgl05171   Coronavirus disease - COVID-19 hgl05200   Pathways in cancer hgl05205   Proteoglycans in cancer hgl05206   MicroRNAs in cancer hgl05207   Chemical carcinogenesis - receptor activation hgl05214   Glioma hgl05223   Non-small cell lung cancer hgl05225   Hepatocellular carcinoma hgl05231   Choline metabolism in cancer hgl05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     101698346 (Prkcg)    04012 ErbB signaling pathway     101698346 (Prkcg)    04014 Ras signaling pathway     101698346 (Prkcg)    04015 Rap1 signaling pathway     101698346 (Prkcg)    04310 Wnt signaling pathway     101698346 (Prkcg)    04370 VEGF signaling pathway     101698346 (Prkcg)    04066 HIF-1 signaling pathway     101698346 (Prkcg)    04020 Calcium signaling pathway     101698346 (Prkcg)    04070 Phosphatidylinositol signaling system     101698346 (Prkcg)    04071 Sphingolipid signaling pathway     101698346 (Prkcg)    04150 mTOR signaling pathway     101698346 (Prkcg)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     101698346 (Prkcg)    04540 Gap junction     101698346 (Prkcg)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     101698346 (Prkcg)    04650 Natural killer cell mediated cytotoxicity     101698346 (Prkcg)    04666 Fc gamma R-mediated phagocytosis     101698346 (Prkcg)    04670 Leukocyte transendothelial migration     101698346 (Prkcg)   09152 Endocrine system    04911 Insulin secretion     101698346 (Prkcg)    04929 GnRH secretion     101698346 (Prkcg)    04921 Oxytocin signaling pathway     101698346 (Prkcg)    04935 Growth hormone synthesis, secretion and action     101698346 (Prkcg)    04918 Thyroid hormone synthesis     101698346 (Prkcg)    04919 Thyroid hormone signaling pathway     101698346 (Prkcg)    04928 Parathyroid hormone synthesis, secretion and action     101698346 (Prkcg)    04916 Melanogenesis     101698346 (Prkcg)    04925 Aldosterone synthesis and secretion     101698346 (Prkcg)   09153 Circulatory system    04270 Vascular smooth muscle contraction     101698346 (Prkcg)   09154 Digestive system    04970 Salivary secretion     101698346 (Prkcg)    04971 Gastric acid secretion     101698346 (Prkcg)    04972 Pancreatic secretion     101698346 (Prkcg)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     101698346 (Prkcg)    04961 Endocrine and other factor-regulated calcium reabsorption     101698346 (Prkcg)   09156 Nervous system    04724 Glutamatergic synapse     101698346 (Prkcg)    04727 GABAergic synapse     101698346 (Prkcg)    04725 Cholinergic synapse     101698346 (Prkcg)    04728 Dopaminergic synapse     101698346 (Prkcg)    04726 Serotonergic synapse     101698346 (Prkcg)    04720 Long-term potentiation     101698346 (Prkcg)    04730 Long-term depression     101698346 (Prkcg)    04723 Retrograde endocannabinoid signaling     101698346 (Prkcg)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     101698346 (Prkcg)   09159 Environmental adaptation    04713 Circadian entrainment     101698346 (Prkcg)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101698346 (Prkcg)    05206 MicroRNAs in cancer     101698346 (Prkcg)    05205 Proteoglycans in cancer     101698346 (Prkcg)    05207 Chemical carcinogenesis - receptor activation     101698346 (Prkcg)    05231 Choline metabolism in cancer     101698346 (Prkcg)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     101698346 (Prkcg)    05214 Glioma     101698346 (Prkcg)    05223 Non-small cell lung cancer     101698346 (Prkcg)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     101698346 (Prkcg)    05161 Hepatitis B     101698346 (Prkcg)    05171 Coronavirus disease - COVID-19     101698346 (Prkcg)    05163 Human cytomegalovirus infection     101698346 (Prkcg)   09174 Infectious disease: parasitic    05146 Amoebiasis     101698346 (Prkcg)    05143 African trypanosomiasis     101698346 (Prkcg)   09164 Neurodegenerative disease    05017 Spinocerebellar ataxia     101698346 (Prkcg)    05022 Pathways of neurodegeneration - multiple diseases     101698346 (Prkcg)   09165 Substance dependence    05031 Amphetamine addiction     101698346 (Prkcg)    05032 Morphine addiction     101698346 (Prkcg)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     101698346 (Prkcg)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     101698346 (Prkcg)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:hgl01001]     101698346 (Prkcg) Enzymes [BR:hgl01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.13  protein kinase C      101698346 (Prkcg) Protein kinases [BR:hgl01001]  Serine/threonine kinases: AGC group   PKC family [OT]    101698346 (Prkcg) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase C1_1 PK_Tyr_Ser-Thr C2 Pkinase_C ABC1 Kinase-like Motif Other DBs NCBI-GeneID:  101698346 NCBI-ProteinID:  XP_004866785 UniProt:  A0A0P6J6X4 LinkDB All DBs Position Un AA seq 697 aa AA seqDB search MAGLGPGGGDSEGGPRPLFCRKGALRQKVVHEVKSHKFTARFFKQPTFCSHCTDFIWGIG KQGLQCQVCSFVVHRRCHEFVTFECPGAGKGPQTDDPRNKHKFRLHSYSSPTFCDHCGSL LYGLVHQGMKCSCCEMNVHRRCVRSVPSLCGVDHTERRGRLQLEIRAPTNEEIHVTVGEA RNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTRTVKATLNPVWNETFVFNLKPGDVERRL SVEVWDWDRTSRNDFMGAMSFGVSELLKAPVDGWYKLLNQEEGEYYNVPVADADNCSLLQ KFEACNYPLELYERVRMGPTSSPIPSPSPSPTDSKRCFFGASPGRLHISDFSFLMVLGKG SFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGGRGPGGRPHFLTQL HSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLFFLHNQGIIYRD LKLDNVMLDAEGHIKITDFGMCKENVFPGTTTRTFCGTPDYIAPEIIAYQPYGKSVDWWS FGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVAICKGFLTKHPAKRLGS GPDGEPTIRAHGFFRWIDWDRLERLEIAPPFRPRPCGRSGENFDKFFTRAAPALTPPDRL VLASIDQADFQGFTYVNPDFVHPDARSPTSPVPVPVM NT seq 2094 nt NT seq  +upstreamnt  +downstreamnt atggccggcctgggccccggcggaggcgactccgaggggggaccccgacctctgttttgc agaaagggggctctgaggcagaaggtggtccacgaagtcaagagccacaagttcaccgct cgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctggggtattgga aaacagggcctgcagtgtcaagtctgcagctttgtggttcatcggcgatgccacgaattc gtgaccttcgagtgtccaggtgctgggaagggcccccagacggacgacccccggaacaag cacaagttccgcctgcacagttacagcagccccaccttctgcgaccactgcggctcgctg ctgtacggcctggtgcaccagggcatgaagtgctcctgctgcgagatgaacgtgcaccgg cgctgtgtgcgcagcgtgccctcgctgtgcggtgtggaccacaccgagcgccgtggccgc ctgcagctggagatccgggccccgaccaacgaggagatccacgtcaccgtcggcgaggcc cgaaacctcattcccatggaccccaacggcctgtctgatccctacgtcaaactgaagctc atcccagacccgcgcaacctgaccaaacagaagactcggacggtgaaagccacgctgaac cccgtgtggaacgagaccttcgtgttcaacctgaagccgggggacgtggagcgcaggctc agcgtggaggtgtgggactgggaccggacttcgcgcaacgacttcatgggggccatgtcc ttcggggtctcggagctgctcaaggcgcccgtggatggctggtacaagttactgaaccag gaggagggtgaatattacaatgtgccggtggcagatgctgacaactgcagcctcctccag aagtttgaggcctgcaactaccccttggaattgtatgagcgagttcggatgggccccaca tcctccccgatcccctccccatcccccagccccaccgactccaagcgctgcttcttcggg gccagcccaggacgcctgcacatctccgacttcagcttcctcatggttctaggaaaaggc agtttcgggaaggtgatgctggcggagcgcagaggctcggacgagctctacgccatcaag atcctgaaaaaggacgtgatcgtccaggacgacgacgtggactgcaccctggtggagaaa cgcgtgctggctctggggggccgaggtccaggcggacggccccacttcctcacccagctg cactccaccttccagactccggaccgcctgtatttcgtgatggagtatgtcaccgggggc gacctgatgtaccacattcagcagctgggcaagttcaaggagccccacgcagcgttctat gccgcagagatcgccatcggcctcttcttccttcacaaccagggcatcatctacagggac ctgaagctggacaacgtgatgctggatgccgaggggcacatcaagatcactgacttcggc atgtgcaaggaaaacgtgttcccggggaccacaacgcggaccttctgtgggaccccggac tacatagcccccgagatcattgcctaccagccctatgggaagtccgtcgattggtggtcc ttcggggtgctgctctacgaaatgttggcagggcagccgccctttgacggggaggatgag gaggagctgtttcaggccatcatggagcagacagtcacctatcccaagtcactttcccgg gaagctgtggccatctgcaaggggttcttgaccaaacacccagcaaagcgcctgggctcc gggcccgacggggaacccacaatccgggcgcacggctttttccgctggatcgactgggac cggctggagcggctggagatcgcgcctccgttcagacctcgcccgtgtggccgcagcggt gagaacttcgacaagttcttcacacgggcggcgccagctctgaccccgccagaccgcctg gtcctggccagcatcgaccaggcggatttccagggcttcacctacgtgaaccccgacttt gtacacccagacgcgcgcagccccaccagccccgtgcccgtgcccgtcatgtga

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