Heterocephalus glaber (naked mole-rat): 101699189
Help
Entry
101699189 CDS
T02812
Symbol
Apc2
Name
(RefSeq) APC2, WNT signaling pathway regulator
KO
K02085
adenomatosis polyposis coli protein
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl04310
Wnt signaling pathway
hgl04390
Hippo signaling pathway
hgl04550
Signaling pathways regulating pluripotency of stem cells
hgl04810
Regulation of actin cytoskeleton
hgl04934
Cushing syndrome
hgl05010
Alzheimer disease
hgl05022
Pathways of neurodegeneration - multiple diseases
hgl05165
Human papillomavirus infection
hgl05200
Pathways in cancer
hgl05206
MicroRNAs in cancer
hgl05210
Colorectal cancer
hgl05213
Endometrial cancer
hgl05217
Basal cell carcinoma
hgl05224
Breast cancer
hgl05225
Hepatocellular carcinoma
hgl05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
101699189 (Apc2)
04390 Hippo signaling pathway
101699189 (Apc2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
101699189 (Apc2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
101699189 (Apc2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101699189 (Apc2)
05206 MicroRNAs in cancer
101699189 (Apc2)
09162 Cancer: specific types
05210 Colorectal cancer
101699189 (Apc2)
05225 Hepatocellular carcinoma
101699189 (Apc2)
05226 Gastric cancer
101699189 (Apc2)
05217 Basal cell carcinoma
101699189 (Apc2)
05213 Endometrial cancer
101699189 (Apc2)
05224 Breast cancer
101699189 (Apc2)
09172 Infectious disease: viral
05165 Human papillomavirus infection
101699189 (Apc2)
09164 Neurodegenerative disease
05010 Alzheimer disease
101699189 (Apc2)
05022 Pathways of neurodegeneration - multiple diseases
101699189 (Apc2)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
101699189 (Apc2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
hgl01009
]
101699189 (Apc2)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
hgl03036
]
101699189 (Apc2)
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
hgl04812
]
101699189 (Apc2)
Protein phosphatases and associated proteins [BR:
hgl01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
101699189 (Apc2)
Chromosome and associated proteins [BR:
hgl03036
]
Eukaryotic type
Centrosome formation proteins
Other centriole associated proteins
101699189 (Apc2)
Cytoskeleton proteins [BR:
hgl04812
]
Eukaryotic cytoskeleton proteins
Microtubules
Tubulin-binding proteins
EB / APC
101699189 (Apc2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
APC_basic
APC_rep
APC_N_CC
APC_r
Arm_APC_u3
Arm
Suppressor_APC
SAMP
bZIP_1
CCDC138_cc
Sec7-like_HUS
MPS2
PDC10_C
HALZ
Motif
Other DBs
NCBI-GeneID:
101699189
NCBI-ProteinID:
XP_004866004
LinkDB
All DBs
Position
Un
AA seq
2322 aa
AA seq
DB search
MGLLGLLSLLHSAFFGDQALHELKMTSSVASYEQLVRQVEALKAENSHLRQELQDNSSHL
SKLESETSGMKEVLKHLQGKLEQEAHMLVSSGQTEVLEQLKALQMDITSLYNLKFQPPAL
GPEPTARTPEGSPVHGSGPSKDSFGELSRATIRLLEELDRERCFLLSEIEKEEKEKLWYY
SQLQGLSKRLDELPHVETQFSMQMDLIRQQLEFEAQHIRSLMEERFGTSDEMVQRAQIRA
SRLEQIDKELLEAQDRVQQTEPQALLAVKSVPVEEDPEAEIPTHPEDGTPQPGNSKVEVV
FWLLSMLATRDQEDTARTLLAMSSSPESCVAMRRSGCLPLLLQILHGAEAGAGGCTGNPG
APGAKDARMRANAALHNIVFSQPDQGLARKEMRVLHVLEQIRAYCETCWDWLQAREKGLE
AGGAGGAPVPIEPQICQATCAVMKLSFDEEYRRAMNELGGLQAVAELLQVDYEMHKMTRD
PLNLALRRYTGMTLTNLTFGDVANKATLCARRGCMEAIVAQLASESEELHQVVSSILRNL
SWRADINSKKVLREVGSMTALMQCVLRATKESTLKSVLSALWNLSAHSTENKAAICQVDG
ALGFLVSTLTYRCQGNSLAVIESGGGILRNVSSLIATREDYRQVLRDHNCLQTLLQHLTS
HSLTIVSNACGTLWNLSARSPRDQELLWDLGAVGMLRNLVHSKHKMIAMGSAAALRNLLA
HRPTKYQAAATAISPGTCVPSLYVRKQRALEAELDTRHLAQALGHLEKQGLPEAEAEATS
KKPLPPLRHLDGLAQDYASDSGCFDDDDAPSLAAAAGNAEPASPAVMSLFLGSPFLQGQA
LARTQPARHSGLEAQKESGGDAAVAAKAKAKLALAVARIDRLVEDISALHTSSDDSFSLS
SGDPGQEVPREGRAHSCSPCRGSEGARREAGSRAHPLLRLKAAHASLSNDSLNSGSTSDG
YCPREHMQPCQLAALAEHREDPLRGQVRPSRLDLDLRGGQAEPPARDTAATADVGVRTIK
LSPTYQHVPLLEGAAGAGARSLAGPGASPGTRKQAWMPVDSLSKVPEKLAGGTPLPAVSK
VLQKLAVQDGPLSLSRCSSLSSLSSTGHPGPSDGGNLDDSDSSLEGLEEAGPGEAELDGG
WRGSGSTSLPVAIPTPRRGRGRGLGVEDATPSSSSENCVQETPLVLSRCSSVSSLGSFES
PSIASSIPSDPCSGLGSGTVSPSELPDSPGQTMPPSRSKTPPAPQGQPETSQFSLQWESY
VKRFLDIADCRERCQPPSELDAGSVRFTVEKPDENFSCASSLSALALHELYVQQDVELRL
RPPACPEREEGTGGGHRRREEAGGHLEGPTPSGSRNRSATDQELKLLRECLGAAVPARLR
KVASALVSGRRALPVPVYMLVPAPARDDDSGTDSAEGTPVNFSSAASLSDETLQGPPRDQ
PCTSTDRQKPTGRAAPSRQASGHWPKAGVAGKSSEQTRGAGRSRAGLELPLGRPPSARSD
RNGSRQGRVRGDGGLQSLCLTTPTEEAVYCFYDSEEEPPVTKVPPPRRASAIPRAQKRDR
PAGRKETHGPSKAAPPARAQPRLIADETPPCYSLSSSASSLSEPEPSEQPASCTRGGESA
VTKDPGPGSQQESSPSPRTEEELLRRCIGSAMPRHRPQPLGCRRRKPRAARPDLRPKEEP
RECAEQVAGSDPASDLDSVEWQAIQEGANSIVTWLHQAAAAATLEASSESDSLLSLVSGL
SMGSMLQSSKQRKGRQPGPRAEAGSTHRSEKRAPAPAKSSGSSRLPGGPEKPRGTRKTAP
GEPAVLRGRTVIYVPSPAPQTQLKGTPGPRPTRKKMGPPGPPQSEAPAKTPSPGQQRSRS
LHRPGKISELAALSHPPRSATPPARLAKTPSSSSSQTSPASQPLPRKSPLATPAAGPLPG
PGISPVPKTPARALLAKQHKTQKSPVRIPFMQRPARRGPPPLARGAPESAPRGRAGPEGI
PRARGSRLGLVRVASARSSGSESSDRSGFRRQLTFIKESPGLLRRRRSELSSAESATSAS
QSASPRRGRPALPAVFLCSSRCDELRASQRQPPAPQRIPVASSPGPGPGPRAPRRTSSES
PSRLPVRAPAPRPEAVKRYASLPHISVAQRPEGAAPAPAEAARRSSDGEARPLPRVAAPG
TMWRRIRDEDVPHILRSTLPATALPLRGPSPDEGPVGAPQRKTSDAVVQTEEVAAPKTNS
STSPSLETRELPQAPAGGPVPVLGSDVDGPGPAKVPAAIPFVHEGLGVAVGGFPASRHGS
PSRAARVPPFNYVPSPMAAVAVTSDPAAVEKAPAGAPAHLLE
NT seq
6969 nt
NT seq
+upstream
nt +downstream
nt
atggggctcctggggctcctgagcctgctgcactcggccttcttcggggaccaggcgctg
catgagctgaagatgacgagctcagtggcctcctatgagcagctggttcggcaggtggag
gccttaaaggctgagaacagtcacctgaggcaggagcttcaggacaactcaagccacctg
tccaagctggagtccgagacctcagggatgaaggaggtcctgaagcacctgcagggcaag
ctggagcaggaggcccacatgctggtgtcgtcggggcagacagaggtgctggagcaactg
aaggctctccagatggacatcaccagcttgtacaacctcaagttccagccaccggccctg
gggcctgagcctactgcccgaacccccgaaggaagcccagtccatggctctgggccctcc
aaggacagctttggggagctgagcagggctaccatccggctcctggaggaactggaccgg
gaacggtgcttcctgctgagcgagatcgagaaagaggagaaggagaagctctggtactac
tctcagctgcagggcctgtccaagcgcctggacgagctgcctcacgtggaaacgcagttc
tccatgcagatggacctgattcggcagcagctggagttcgaggcccagcacatccgctcg
ctcatggaggagcgctttgggacctcggacgagatggtgcagcgtgcacagatccgagct
tcgcgcctggagcaaattgacaaggagctgctggaggcacaggaccgggtgcaacagact
gagcctcaggccctactggcagtgaagtcggtgccggtggaggaggaccccgaggcggag
atccccacgcaccctgaggatggtaccccgcagccgggcaacagcaaggtggaggtggta
ttctggctgctgtccatgctggcgacgcgtgaccaggaggacacggcccgcacgctgttg
gccatgtccagctctcctgagagctgcgtggccatgcgccgttcaggctgcctgccgctg
ctgctgcagatcctccacggcgccgaggcgggggcagggggttgcacaggaaacccggga
gccccaggagccaaggacgcgcgcatgcgggccaatgccgcactgcacaacatcgtcttc
tcgcagcccgaccagggcctggctcgcaaagagatgcgcgtcctgcacgtgctggagcag
atccgagcgtactgcgagacctgctgggactggctgcaggcccgagagaaggggctggag
gcgggcggcgccggcggcgcccctgtccccattgagcctcagatctgccaggccacctgt
gctgtgatgaagctgtcctttgatgaggaataccgccgggccatgaacgagctcggtggt
ctgcaagcggtggcggaactgctgcaggtggactacgagatgcacaagatgacccgagac
cccctgaaccttgccctgcgccgctacacaggcatgaccctaaccaacctcaccttcgga
gacgttgccaacaaggccaccctctgtgcccgccggggctgcatggaggccatcgtggcc
cagctggcatctgagagtgaggagctccatcaggtggtgtctagcatcctgcgcaacctg
tcctggagagcagacatcaacagcaagaaagtgcttagggaggtcggcagtatgacggcc
ctgatgcagtgtgtccttcgggccaccaaggagtccaccctgaagagcgtgcttagcgcc
ctgtggaacctgtcggcgcacagcacggagaacaaagcggccatctgccaggtggacggt
gcgctcggcttcctggtgagcaccctgacctaccgctgtcagggcaactccctggctgtc
attgagagtggcggcggcatccttcgcaacgtgtccagcctcattgccacgcgcgaggac
tacaggcaggtactgcgagaccacaattgcctgcagacccttctgcaacacttgacgtcg
cacagcctgaccatcgtgagcaacgcatgtggcacgctctggaacctgtctgcacgcagc
cctcgcgatcaggagctgttgtgggacctgggggctgtgggcatgctgcgaaacctggtg
cattccaagcacaagatgatcgccatgggcagcgcggctgccctacgcaacctgctggcc
catcggcccacaaagtaccaggcagcagccacagccatctccccaggcacctgtgtgccc
agcctttatgtgcggaagcagcgggcactggaggctgagctggacacccggcacctggca
caggcactgggccacctggagaagcagggtctgcctgaggccgaggctgaggccacctcc
aagaaaccgctgccacccctgcggcacctggatggattggcccaggactatgcctccgac
tctggctgcttcgatgatgatgatgcaccgtccctggcggcggctgccggcaacgcggag
cccgccagtccagctgtaatgtccttgttcctgggcagccccttcctgcagggccaggct
ctggcccgcacccagcctgcccgtcacagtggcctggaggctcagaaggagtctggggga
gatgctgctgtggcagccaaggccaaagccaagctggcactagcagttgctcgaattgac
cggctggtggaggacatctccgctctgcacacctcgtctgatgacagcttcagcctcagt
tctggggaccccgggcaggaggtccccagggagggccgcgctcattcctgctcaccatgc
cggggctctgagggtgcgcggagggaggctggcagccgggcccatccgctgctccgtctc
aaagccgcacacgccagcctttccaatgacagtctcaacagtgggagcaccagcgatggc
tactgccctcgggagcacatgcaaccctgccagctggctgcgctggctgagcaccgggag
gaccctctgcgtgggcaggtgcggcccagccggctggaccttgacctgcgtgggggccag
gctgagccgcctgcacgtgacaccgcggctactgctgatgtgggggtgcgcaccatcaag
ctgtcacccacctatcagcatgtgccgctgctagagggtgcagccggggcgggggcacgg
tcccttgctgggcctggggcctcgcctggtacccggaagcaagcgtggatgcctgtggac
agcctcagcaaggtgcctgagaagctggcaggtggcactccattgcctgcggtcagcaag
gtcctgcagaagctggcagtgcaggatgggccactgtccctctcccgctgcagctctctg
tcctcactgtcctccactggccatcctggccccagtgacggtggtaacctggatgatagt
gactcttccttggagggactggaggaggctggccctggggaggcagaactggatgggggt
tggcgggggtccgggtccacctcactgccagtggccattcctacaccccgcaggggccgt
gggcggggcctgggggtggaggatgccacgccatccagctcatcggagaactgtgtgcag
gagacgcccctggttctgagtcgctgcagctcagtgagctcactgggcagcttcgaaagc
ccttcaattgccagctctatccccagcgacccatgcagtgggctgggcagtgggactgtc
agtcctagcgagctgcccgacagccctgggcagaccatgccgcccagccgcagcaagaca
ccgccggcgccacagggccagccagagaccagccagttcagcctgcagtgggagagctac
gtcaagcgcttcctggacattgctgactgccgagagcgctgccagccgccatctgagctg
gatgctggcagtgtacgcttcactgtggagaagccagatgagaacttctcctgcgcctcc
agcctcagcgcactggctctgcacgagctgtatgtgcagcaggatgtagaacttcggctg
cggccgcctgcttgcccggagcgcgaggaaggcacaggtggagggcaccgccggcgggag
gaggctggtggccacctggagggacctacaccatccgggtctcgcaaccgctcagccact
gaccaggaactgaagctgcttcgagagtgtctgggggctgctgtgccagcccggctccga
aaagtggcctcagcgctggtgtccggccgccgtgccctgccggtaccagtctatatgctg
gttccagccccagccagggacgatgactctggcaccgactctgctgagggcacaccagtc
aacttctccagcgctgcctcactcagtgatgagaccctgcaggggccccccagggaccag
ccctgcacctccacagacaggcagaagcccacaggccgcgcagctccctccaggcaggcc
tctgggcactggcccaaggcaggggttgctggaaagagctctgaacagacccggggggct
ggcaggagcagggctggtctggaactgcctctcggccggcctccaagtgcacggtctgac
aggaatggctctcgccagggtcgcgtgcgtggtgatgggggtctgcagtccctgtgcctc
accacgcccaccgaggaggctgtgtactgcttctatgactcggaggaggagccacctgtc
accaaggtgccgcccccgcggcgggcatccgcaattcctcgggcccagaagcgggatcga
cctgctggccggaaggagacccacggtccctccaaggctgctccacctgcccgggcccag
cccaggctgattgcagatgagactccgccttgctattccctgagctcctcagccagctcc
ctcagcgagccggagccatctgagcagccagccagctgtactcgaggtggtgagtcagca
gtcaccaaggatccaggccctggcagccaacaggaaagctccccaagcccacgcactgag
gaggagctgttgcggaggtgcatcggctcagccatgcccaggcaccggcctcagcccttg
ggctgtaggcgtcgaaagccccgagctgcccggccagacctaaggccaaaggaggagccc
cgagagtgtgccgagcaggtggcaggctccgacccagcctctgacctggacagcgtggag
tggcaggccatccaggagggtgccaactccatcgtcacgtggctgcaccaagccgcagct
gcagccaccctggaggcctcatctgagtctgactccctcctgtccttggtgtctgggctg
tccatgggttctatgcttcaatcatccaagcagaggaaagggcgacagccagggccaagg
gcagaggcaggaagcactcatcggtcagagaaaagggctccggccccagccaagagcagt
gggagctcccgcttgcctggaggtccagagaagcctcggggcacccggaagactgcacct
ggggaaccggctgtgctccgaggacgcacagtgatatatgtgcccagtcccgctccgcag
acccagctcaaaggcaccccgggtccccgccccacacggaagaagatggggcctcctggg
cccccacagtcggaagccccagccaaaacccccagccctgggcaacagaggtctcggagc
ctgcatcgaccgggcaagatctccgagctggccgctctgagccaccccccgaggagcgcc
acaccgcccgcccgccttgccaagaccccgtcctctagctcctctcagacctcacctgcc
tcccagcccttgcccaggaagtcccctctggccacgccggcagcagggcccctccctggc
cctggaatctccccggtgcccaagaccccagctcgggcccttctggccaaacagcacaag
acacagaagtcgccggtgcgcatcccgttcatgcagagacccgccaggcgagggccaccg
ccactggccaggggagccccagaatcggcccccaggggtcgggcggggccagaggggatc
ccccgggcgcgtgggagccgcctgggtctggtgcgcgtggcctcggcgcgctccagcggc
agcgagtcctccgatcgctcgggtttccggcgacaactaactttcatcaaggagtccccg
ggtttgttgcgtcgccggcgctctgagctgtcctccgcagagtccgcgacctccgcctcc
cagagcgcctctccgcgccgcggccggcccgccctacccgcggtcttcctctgctcctca
cgctgcgacgagctgcgggcctcccagcggcagcccccggccccgcagcggatcccggtg
gcgtcgagtcccgggcccggccccggcccccgcgcgccccggcgcaccagctccgagagc
ccctcgcgcctgcccgtgcgcgcccccgcgccgcggccggaggcggtcaaacgctacgcg
tcattgccgcacatcagcgtggcccaaaggcccgagggcgccgcccccgctcctgctgaa
gctgcccgccgcagcagcgacggggaagccaggccgttgccgagggtggcggccccgggc
accatgtggcggcgcatccgcgacgaggatgtcccgcacatcctgcgcagcacgctgccc
gccactgccctgccactcaggggcccttcgcccgacgaaggcccggtcggggctccgcag
cgcaagaccagcgatgccgtggtgcagacggaggaggtggccgcgcccaagaccaactct
agcacctccccgagcctggagactcgggagctccctcaggccccggctgggggccccgtc
cccgttttgggcagcgacgtggacgggcctggccccgccaaggtccctgccgctatcccc
ttcgtccacgagggccttggcgtggctgtggggggcttccccgctagccggcatgggtct
cccagccgcgctgcgcgggtcccgcctttcaactacgtgcccagccccatggcagcggtg
gcagtgaccagcgaccctgcggcggtggaaaaggccccggccggggccccagcccacctc
ttggagtag
DBGET
integrated database retrieval system
