Heterocephalus glaber (naked mole-rat): 101699730
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Entry
101699730 CDS
T02812
Symbol
Ehhadh
Name
(RefSeq) enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
KO
K07514
enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase [EC:
4.2.1.17
1.1.1.35
5.3.3.8
]
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl00071
Fatty acid degradation
hgl00280
Valine, leucine and isoleucine degradation
hgl00310
Lysine degradation
hgl00380
Tryptophan metabolism
hgl00410
beta-Alanine metabolism
hgl00640
Propanoate metabolism
hgl00650
Butanoate metabolism
hgl01100
Metabolic pathways
hgl01212
Fatty acid metabolism
hgl03320
PPAR signaling pathway
hgl04146
Peroxisome
Module
hgl_M00032
Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
hgl_M00087
beta-Oxidation
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
101699730 (Ehhadh)
00650 Butanoate metabolism
101699730 (Ehhadh)
09103 Lipid metabolism
00071 Fatty acid degradation
101699730 (Ehhadh)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
101699730 (Ehhadh)
00310 Lysine degradation
101699730 (Ehhadh)
00380 Tryptophan metabolism
101699730 (Ehhadh)
09106 Metabolism of other amino acids
00410 beta-Alanine metabolism
101699730 (Ehhadh)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
101699730 (Ehhadh)
09150 Organismal Systems
09152 Endocrine system
03320 PPAR signaling pathway
101699730 (Ehhadh)
Enzymes [BR:
hgl01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.35 3-hydroxyacyl-CoA dehydrogenase
101699730 (Ehhadh)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.17 enoyl-CoA hydratase
101699730 (Ehhadh)
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.8 Delta3-Delta2-enoyl-CoA isomerase
101699730 (Ehhadh)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
3HCDH_N
ECH_1
3HCDH
ECH_2
UDPG_MGDP_dh_N
NAD_binding_2
TrkA_N
F420_oxidored
2-Hacid_dh_C
ApbA
UPF0180
Motif
Other DBs
NCBI-GeneID:
101699730
NCBI-ProteinID:
XP_004834902
UniProt:
A0A0P6JVW9
LinkDB
All DBs
Position
Un
AA seq
724 aa
AA seq
DB search
MAEYLRLPHSLALIRLRNPPVNTISLPVIRGIREGLKKAALDNTIKAIVISGADGNFCAG
ADIHSFKAPISSAEGLGLLVDEIQRYGKPVVAAIQGVALGGGLELALGCHYRIAHAQAQV
GFPEVTIGILPGGRGTQLLPRLIGIPAALDLITSGRYILAGEALKLGILDEVMKSDSLEE
AIKFTQKILDQPLEPRRILNRPVPSLSNMENTFTEAFAKMRKQYPGYLAPETCVRSVQAS
MKYPYEEGIRKEEELFQYLRESGQARALQYAFFAERSVNKWSTPSGASWKTATARPISSV
GVLGLGTMGRGIAISFARVGIPVIAVESDQKQLEAAKKIVTSTLEKEAAKSMQQSGQRES
APKPRFSSSMKELASVDLVIEAVFEDMNLKKQVFAELSAVCKPEAFLCTNTSALDVDEIA
ASTSRPQLVIGTHFFSPAHVMKLVEVIPSRHSSPTTIATVMNLSKKMKKIAVVVGNCYGF
VGNRMLQPYFNQTYFLLEDGSKPEDIDQALEEFGLKMGPLRMSDLAGLDVGWKVRKGRGL
TGPALPPGTPARKRGNARYSPIPDMLCDLGRFGQKTGQGWYLYDKPLGRVHKPDPWLSKF
LSEYRETHHIKPRVIDQDEIRERCLYALINEAFHILGEGMAASPEHIDVIYLHGYGWPRH
RGGPMFYASTVGLPTVLEKLQKYYQQNPDIPQLEPCNYLKKLASQGNPPLKEWQSLAGPP
SSKL
NT seq
2175 nt
NT seq
+upstream
nt +downstream
nt
atggctgagtaccttcggctgccccactcgctggcgctgatccgcctccgaaacccgccg
gtaaacacgatcagtttgcctgtaatccgtggaataagagagggactaaagaaagctgca
ttggacaatacaataaaagccattgtgatttctggagcagatggcaacttttgtgcaggt
gcagatatccacagcttcaaagcccctatatcctctgctgaaggactgggacttttagta
gatgaaattcagagatatggaaagcccgtggtggcggctatccaaggtgtggccttagga
ggagggctggagctggccctgggctgtcactacaggattgcccacgcacaggctcaagtt
ggtttcccagaagtcacaatagggattcttcctggtggaagaggcacccagctgctcccc
agactcattggaattcctgctgcccttgacttaattacctcaggaagatatattttggca
ggtgaagcactcaagttgggtattttggatgaggttatgaagtcagactcacttgaagag
gcaatcaaattcacccagaaaattttagatcaacctctagaacctcgcagaatcctcaac
aggccagttcccagcttgtccaacatggaaaacactttcactgaagcctttgcgaagatg
cggaagcagtaccctgggtaccttgctccggagacctgtgtccgttcagtccaggcctcc
atgaagtacccctatgaagagggaatcaggaaagaggaggagctgtttcagtaccttcgg
gaatctgggcaggccagagccctgcagtatgctttctttgctgagagaagtgtaaataag
tggtcaaccccatctggggcatcctggaaaacagctactgcacgacccatctcctcagtt
ggtgttcttggcttgggaacaatgggtcgaggcattgccatttcttttgcaagagtcggg
atccctgtgattgctgtagaatcagaccaaaagcagctagaagctgcaaagaagatagtg
acttccaccttggaaaaggaagcagccaaaagcatgcaacagagtggccaacgtgagtca
gcaccaaaacctaggttcagttcatctatgaaggagctggccagtgtcgatttagtcatt
gaagcagtatttgaggacatgaacctgaagaagcaggtctttgctgaactttcagctgtg
tgcaagccagaagcatttctgtgcactaatacttcagccctggacgtggatgagattgct
gcgtccaccagtcgtcctcagctggtcatcggcactcatttcttctccccagctcatgtc
atgaagttggtagaggtcattcccagccgacactcttcccccactaccattgccactgtt
atgaacctatcgaagaagatgaaaaagattgcagtagttgtaggcaactgttatggattt
gttgggaatcgaatgttgcaaccttattttaaccagacttatttcttgttagaagatggc
agtaagccagaggacatagatcaggcactggaagagtttggtcttaagatggggccactt
cggatgtctgatcttgctggcttagatgtgggctggaaagttcgcaaggggcgaggtctt
actgggcctgcgctgcctccaggaactcctgcccgaaaacgaggcaatgcaagatacagc
cccattcctgatatgctctgtgacttaggacggtttggccagaagaccgggcagggttgg
tatctatatgacaagccattgggtagggttcacaaacctgacccctggctttccaaattc
ctgtcagagtacagggagacccatcacatcaaaccacgggtcattgaccaggatgagatc
cgggagcgctgcttgtatgcactgatcaacgaagccttccacatcttgggagaagggatg
gctgccagcccagagcacattgatgtgatctacttgcatgggtacggctggccgcgccac
aggggcgggcccatgttctatgcctccacagtggggctgcccacggttctggagaagctg
cagaagtattaccagcagaatcctgatattccccaactggagccctgcaactatctcaaa
aagctggcttcccagggaaaccctcctctgaaagaatggcagagcttggcagggccgccc
agcagtaaattgtga
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