KEGG   Heterocephalus glaber (naked mole-rat): 101701311
Entry
101701311         CDS       T02812                                 
Name
(RefSeq) cytochrome P450 11B1, mitochondrial
  KO
K00497  steroid 11beta-monooxygenase [EC:1.14.15.4]
Organism
hgl  Heterocephalus glaber (naked mole-rat)
Pathway
hgl00140  Steroid hormone biosynthesis
hgl01100  Metabolic pathways
hgl04927  Cortisol synthesis and secretion
hgl04934  Cushing syndrome
Module
hgl_M00108  C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone
hgl_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:hgl00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    101701311
 09150 Organismal Systems
  09152 Endocrine system
   04927 Cortisol synthesis and secretion
    101701311
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    101701311
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:hgl00199]
    101701311
Enzymes [BR:hgl01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.4  steroid 11beta-monooxygenase
     101701311
Cytochrome P450 [BR:hgl00199]
 Cytochrome P450, animal type
  CYP11 family
   101701311
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 101701311
NCBI-ProteinID: XP_004837917
LinkDB
Position
Un
AA seq 501 aa
MTFRLKADIWLAGSWLCLRGARALGTRAVVAPKTTVLPFKAIPQYSGNKWQKVLQIWKGQ
DYDDLHLEVDRAFQELGPIFRYNMGKTQIVSVMLPEDADQLYLAEKVYPYRKVMEPWIAH
RQHRGKKPGVFLLNGPEWHSDRLQLNPNVLSPKAVQKFLPMVDIVARDFSEALKKKVLQS
AQRILTLGIQPSICNYSIEASNFALFGERLGLLGHNPSPNSLNFIHALETMFKSTRKLMF
LPRYLPSWMSSQVWKEHFEAWDHISDYAENCIQKKYQELAAGSPQYYSGIMADMLLDGDS
SLGVIMANSLDFIAGSVDTTTYPIMMTLFELARNPTVQQALHQESLAAEPSISGNPQRAT
MELPLLRAALKETLRLYPVGLFLERILSSDLVLQNYHLPAGTLVHLYLYSMGRNPSVFPS
PERYNPQRWLDSRQTFHHLAFGFGVRQCLGRRLAEVEMLLFLHHILKSFHVETPLQEDVK
LAYNFVLMPTTFPPLTFRAVT
NT seq 1506 nt   +upstreamnt  +downstreamnt
atgacatttaggttgaaggcagacatttggctggcagggtcctggctgtgcctgagaggc
gccagggcactgggcaccagagctgttgtggcccccaagactacagtgctgcccttcaaa
gccataccccagtactcaggcaacaaatggcagaaggtgctgcagatctggaaggggcag
gactatgatgacttgcacctggaggtagatcgggccttccaggagctggggcccattttc
aggtataacatgggaaagacacagatagtctctgtgatgctgccagaggacgctgaccag
ctgtacctggcagagaaagtgtatccataccgcaaggtcatggagccctggatagcccac
agacagcaccgagggaagaagcctggagtgttcttgctgaatgggcctgaatggcactct
gaccgactacagctgaacccaaatgtgctgtccccaaaggcagtgcaaaagttcctcccc
atggtggacatagtggcaagagacttctcagaggccttgaagaagaaggtgctacagagt
gcccagcggatcctgaccctgggcatccagcccagcatttgtaactatagcatagaagcc
agcaactttgcactttttggagagaggttgggcctcctaggtcataacccgagccctaac
agcctgaacttcatccatgccctggagaccatgttcaaatccaccaggaagctcatgttc
ttgcccaggtatctgcccagctggatgagcagccaggtgtggaaggagcactttgaggcc
tgggaccacatctctgactatgctgaaaattgcatccagaagaaataccaggagctggct
gcaggatcccctcagtactacagcggcatcatggcagatatgctgttggatggggactca
tcactaggtgtcatcatggccaactctttggacttcattgcagggagtgtggacacgacc
acctacccaataatgatgacgctctttgagttggccaggaaccccacggtgcagcaggcc
ctgcaccaggaaagcctggctgctgagcccagcatctcagggaatcctcagagggctacc
atggaactgcccctgcttcgagcagccctcaaggagaccctgaggctgtaccctgtcggt
ctttttctggagagaatcctgagctcagacttggtgcttcagaactaccacctcccggct
gggaccttggtccatttgtatctgtattcaatgggccgaaacccctcagtgttcccgagt
ccagagcgctataacccgcaacgctggctggacagcaggcagaccttccatcacctggct
tttggctttggggtgcgccagtgtctggggcggcgtctggcagaagtggagatgctgctg
tttctgcatcacattctgaaatccttccacgtggagacaccgctccaagaggatgtgaag
ttggcctacaactttgttttgatgcccaccaccttcccccccctcactttccgggctgtc
acctag

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