Heterocephalus glaber (naked mole-rat): 101701670
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Entry
101701670 CDS
T02812
Symbol
Ndufs2
Name
(RefSeq) NADH:ubiquinone oxidoreductase core subunit S2
KO
K03935
NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:
7.1.1.2
]
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl00190
Oxidative phosphorylation
hgl01100
Metabolic pathways
hgl04714
Thermogenesis
hgl04723
Retrograde endocannabinoid signaling
hgl04932
Non-alcoholic fatty liver disease
hgl05010
Alzheimer disease
hgl05012
Parkinson disease
hgl05014
Amyotrophic lateral sclerosis
hgl05016
Huntington disease
hgl05020
Prion disease
hgl05022
Pathways of neurodegeneration - multiple diseases
hgl05208
Chemical carcinogenesis - reactive oxygen species
hgl05415
Diabetic cardiomyopathy
Module
hgl_M00143
NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09100 Metabolism
09102 Energy metabolism
00190 Oxidative phosphorylation
101701670 (Ndufs2)
09150 Organismal Systems
09156 Nervous system
04723 Retrograde endocannabinoid signaling
101701670 (Ndufs2)
09159 Environmental adaptation
04714 Thermogenesis
101701670 (Ndufs2)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
101701670 (Ndufs2)
09164 Neurodegenerative disease
05010 Alzheimer disease
101701670 (Ndufs2)
05012 Parkinson disease
101701670 (Ndufs2)
05014 Amyotrophic lateral sclerosis
101701670 (Ndufs2)
05016 Huntington disease
101701670 (Ndufs2)
05020 Prion disease
101701670 (Ndufs2)
05022 Pathways of neurodegeneration - multiple diseases
101701670 (Ndufs2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
101701670 (Ndufs2)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
101701670 (Ndufs2)
Enzymes [BR:
hgl01000
]
7. Translocases
7.1 Catalysing the translocation of protons
7.1.1 Linked to oxidoreductase reactions
7.1.1.2 NADH:ubiquinone reductase (H+-translocating)
101701670 (Ndufs2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Complex1_49kDa
NiFeSe_Hases
Motif
Other DBs
NCBI-GeneID:
101701670
NCBI-ProteinID:
XP_004858719
UniProt:
G5BWI0
LinkDB
All DBs
Position
Un
AA seq
463 aa
AA seq
DB search
MAALRALCTLRGVGAQVLRLGPAVRLPVQPSRGARQWQPDVEWAEQFGGAVMYPTKETAH
WKPPPWNDVDPPKEQTVSNLTLNFGPQHPAAHGVLRLVMELSGEMVQKCDPHIGLLHRGT
EKLIEYKTYLQALPYFDRLDYVSMMCNEQAYSLAVEKLLNIQPPPRAQWIRVLFGEITRL
LNHIMAVTTHALDVGAMTPFFWMFEEREKLFEFYERVSGARMHAAYIRPGGVHQDLPLGL
MDDIYEFSKNFSLRIDEVEEMLTNNRIWQNRTVDIGVVKAEDALNYGFSGVMLRGSGIQW
DLRKTQPYDVYDQVEFDVPVGSRGDCYDRYLCRVEEMRQSLRIIEQCLNKMPPGEIKVDD
AKVSPPKRSEMKTSMESLIHHFKLYTEGYQVPPGATYTAIEAPKGEFGVYLVSDGSSRPY
RCKIKAPGFAHLAGLDMMSKGHMLADVVAIIGTQDIVFGEVDR
NT seq
1392 nt
NT seq
+upstream
nt +downstream
nt
atggcggcgctgagggcactttgcaccctccggggcgtcggggcccaagtactgcgactc
gggcctgcagtccgactgcctgtgcagcccagcagaggcgctcggcagtggcaacccgat
gtggaatgggcagagcagtttgggggcgctgtcatgtaccccaccaaggaaacagcccac
tggaaacctccaccttggaatgatgtggaccctccaaaggaacaaacagtttccaaccta
accctgaactttggaccccagcacccagcagcccatggagtcctgcggctagtgatggag
ctgagtggagagatggtgcagaagtgcgaccctcacatcggtctcctgcaccggggcact
gagaagctcattgagtacaagacttacctgcaggcccttccatactttgaccggctagac
tacgtgtccatgatgtgtaacgagcaggcgtattcactggctgtggagaagctgctgaac
atccagcctccaccccgggcacagtggatccgagtgctgtttggagaaatcacaagactt
ttgaaccacatcatggctgtgaccacacatgccctggacgttggggccatgacccctttc
ttctggatgtttgaggaaagggaaaagctgtttgagttctacgagcgggtgtctggagcc
cgaatgcacgctgcttatattcgcccgggaggtgtgcaccaggacctaccccttggcctt
atggatgacatttatgagttttccaagaacttctctcttcggattgacgaagtggaggag
atgctgactaacaataggatctggcagaatcgcacagtggacattggagttgtaaaagcc
gaagatgcacttaactatggttttagtggagtgatgctccggggctcaggtatccagtgg
gatctgcggaagacccagccttatgatgtttacgaccaggtcgagtttgatgtccctgtt
ggttctcgaggggactgctatgataggtacctgtgtcgggtggaggagatgcgccagtcc
cttcgcatcatcgagcagtgtctgaacaagatgcctcctggagagatcaaggttgacgat
gccaaagtgtctccacccaagcgctcagagatgaagacttccatggagtcattgattcat
cactttaagttgtatactgagggctaccaagtccccccaggagccacgtacactgctatt
gaggctcctaagggagagtttggggtgtacctggtgtcggatggcagcagccgcccttac
cgttgcaagatcaaggctcctggttttgcccacctggctggcttggacatgatgtctaag
ggacacatgttggcggatgttgtcgccatcataggtacccaagatattgtgtttggagaa
gttgatcggtga
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