Heterocephalus glaber (naked mole-rat): 101706028 Help Entry 101706028         CDS       T02812                                  Symbol Acaca Name (RefSeq) acetyl-CoA carboxylase alpha   KO K11262   acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15] Organism hgl  Heterocephalus glaber (naked mole-rat) Pathway hgl00061   Fatty acid biosynthesis hgl00620   Pyruvate metabolism hgl00640   Propanoate metabolism hgl01100   Metabolic pathways hgl01212   Fatty acid metabolism hgl04152   AMPK signaling pathway hgl04910   Insulin signaling pathway hgl04922   Glucagon signaling pathway hgl04936   Alcoholic liver disease Module hgl_M00082   Fatty acid biosynthesis, initiation Brite KEGG Orthology (KO) [BR:hgl00001]  09100 Metabolism   09101 Carbohydrate metabolism    00620 Pyruvate metabolism     101706028 (Acaca)    00640 Propanoate metabolism     101706028 (Acaca)   09103 Lipid metabolism    00061 Fatty acid biosynthesis     101706028 (Acaca)   09110 Biosynthesis of other secondary metabolites    00254 Aflatoxin biosynthesis     101706028 (Acaca)  09130 Environmental Information Processing   09132 Signal transduction    04152 AMPK signaling pathway     101706028 (Acaca)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     101706028 (Acaca)    04922 Glucagon signaling pathway     101706028 (Acaca)  09160 Human Diseases   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     101706028 (Acaca) Enzymes [BR:hgl01000]  2. Transferases   2.1  Transferring one-carbon groups    2.1.3  Carboxy- and carbamoyltransferases     2.1.3.15  acetyl-CoA carboxytransferase      101706028 (Acaca)  6. Ligases   6.3  Forming carbon-nitrogen bonds    6.3.4  Other carbon-nitrogen ligases     6.3.4.14  biotin carboxylase      101706028 (Acaca)   6.4  Forming carbon-carbon bonds    6.4.1  Ligases that form carbon-carbon bonds (only sub-subclass identified to date)     6.4.1.2  acetyl-CoA carboxylase      101706028 (Acaca) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  ACC_central Carboxyl_trans CPSase_L_D2 ACCA_BT Biotin_carb_N Biotin_carb_C Biotin_lipoyl ATP-grasp Dala_Dala_lig_C ATP-grasp_3 ATP-grasp_4 MetallophosN Motif Other DBs NCBI-GeneID:  101706028 NCBI-ProteinID:  XP_004870465 LinkDB All DBs Position Un AA seq 2346 aa AA seqDB search MDEPSSLAEPLELNQHSRFIIGSVSEDNSEDEISNLAKLDLLEEKEGSLSPASCSSDTLS DLGISSLQDGLASHIRSSMSGLHLVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEK VLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPG GPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMWAL GDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQELYEKGYVKDVDDGLKA AEEVGYPVMIKASEGGGGKGIRKVNNADDFSNLFRQVQTEVPGSPIFVMRLAKQSRHLEV QILADQYGNAISLFGRDCSVQRRHQKIIEEAPAAIATPAVFEHMEQCAVKLAKMVGYVSA GTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLFRIKDIRMMY GVSPWGDAPIDFENSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGY FSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLET ESFQLNRIDTGWLDRLIAEKVQAERPDTMLGVVCGALHVADVSLRNSISNFLHSLERGQV LPAHTLLNTVDVELIYDGIKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDG SSYTTYMKEEVDRYRITIGNKTCVFEKENDPSVMRSPSAGKLIKYIVEDGGHVFSGQSYA EIEVMKMVMTLTAAESGCIHYVKRPGAALDPGCVIAKMQLDNPSKVQQAELHTGSLPWIQ STALTGEKLHRVFHCVLDNLVNVMNGYCLPDPFFSSRVKDWVERLMKTLRDPSLPLLELQ DIMTSVSGRIPLNVEKSIKKEMAQYASNITSVLCQFPSQQIANILDSHAATLNRKSEREV FFMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLRVETQFQNGHYDKCVFALREENKSD MNTVLNYIFSHAQVTKKNLLVTMLIDQLCGRDPTLTDELLTILTELTQLSKTTNAKVALR ARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYH SNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNRGNIPTLNRM SFSSNLNHYGMTHVASVSDVLLDNSFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFCDSP PQSPTFPEAGHTSLYDEDKVPRDEPIHILNVAIKTDCDIEDDSLAAMFREFTQQNKATLV DHGIRRLTFLVAQKDFRKQVNCEVDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQ LELNRMRNFDLTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFE YLQNEGERLLLEAMDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYG SRLWKLRVLQAELKINIRLTPTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQA YGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSTQA FLPSPPLPSDMLTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMILKSPEYPEGRDIIVI GNDITYLIGSFGPQEDLLFLRASELARAEGIPRIYVAANSGARIGLAEEIRHMFHVAWVD PEDPYKGYKYLYLTPQDYKRVSALNSVHCEHVEDEGESRYKITDIIGKEEGLGAENLRGS GIIAGESSLAYDEIITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGR EVYTSNNQLGGIQIMHNNGVTHSTVCDDFEGVFTVLHWLSYMPKSVHSSVPLLNSKDPID RIIEFVPTKAPYDPRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGG IPMGVVAVETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNREGLPL MVFANWRGFSGGMKDMYDQVLKFGAYIVDGLRECSQPVMVYIPPQAELRGGSWVVIDPTI NPRHMEMYADRESRGSVLEPEGTVEIKFRKKDLVKTMRRVDPVYIRLAERLGTPELSPVE RKELENKLKEREEFLIPIYHQVAVQFADLHDTPGRMQEKGVINDILDWKTSRTFFYWRLR RLLLEDLVKKKIHNANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLVEWLEKQLTE EDGVRSVVEENIKYISRDYVLKQIRSLVQANPEVAMDSIVHMTQHISPTQRAEIVRILST MDSPST NT seq 7041 nt NT seq  +upstreamnt  +downstreamnt atggatgaaccatcttccttggctgaacctctggagctgaaccagcactctcgattcata attggttccgtgtctgaagataactcagaagatgagatcagcaacttggcgaagttggac ctactggaggagaaggagggctctttgtcaccagcttcttgcagctcagatacactctct gatttgggaatctccagcttacaggatggtttagcctcacacataaggtccagtatgtct gggttgcacctagtaaaacaaggtcgagaccggaagaaaatagactcacagcgagatttc actgtggcttctccagcagaatttgttactcgttttgggggaaataaggtgattgagaag gttcttattgctaataatggcattgcagcagtgaaatgcatgagatctatccggcggtgg tcttatgaaatgtttcgaaatgagcgtgcaattcgatttgttgtcatggtcacacctgaa gaccttaaagcaaatgcagaatacattaagatggccgatcattatgtgccagtgcctgga ggaccaaacaacaacaactatgcaaatgtggaattaattcttgacatcgctaaaaggatc ccagtacaagcagtgtgggctggttggggtcatgcttctgagaatcccaagctcccagaa cttctcttgaaaaatggcattgccttcatgggtcctccaagccaggccatgtgggctttg ggggataagattgcgtcttccattgtagctcagactgcaggtatcccaactcttccctgg agtggcagtggtcttcgtgtggactggcaggaaaatgatttttcgaaacgtatcttaaat gttccacaggaactctatgaaaaaggttatgtgaaggatgtggatgatgggctgaaggct gcagaagaagttggatatccagtgatgatcaaggcctcagaaggaggaggagggaagggc atcaggaaagtcaacaatgcagatgatttttctaacctcttcagacaggttcaaactgaa gtccctggatctcctatatttgtgatgagactagccaaacagtctcgtcatctagaggta cagatcctagcagatcagtatggcaatgccatctctttgtttgggcgggactgctctgta caacgtaggcatcagaagattattgaagaagcacctgctgctattgctactccagcagta tttgaacacatggaacagtgtgcggtgaaacttgccaaaatggttggttatgtgagtgct ggaactgtggaatatttgtacagccaggatggcagcttctactttctggaactgaaccct cggctacaggtggagcacccttgtacagaaatggtggctgatgtcaatcttcctgcagca caactccagattgccatggggatccctctatttagaatcaaggatatccggatgatgtat ggggtatctccctggggtgatgctcctattgattttgaaaattctgctcacgttccttgc ccaaggggccatgtcattgctgcccggatcactagtgaaaatccagatgagggttttaag cccagctcaggaacagttcaggaactaaatttccgcagcaacaagaatgtttggggttat ttcagtgttgctgctgcaggaggacttcatgaatttgctgattctcagtttggtcactgc ttttcctggggagaaaacagagaagaagcaatttcaaatatggtggtggctttgaaggag ctctctattcggggtgattttcgaactacagttgaatacctgatcaaattattagagact gaaagctttcagttgaatagaattgacactggttggctggacagactgatagcagaaaaa gtacaggcagaacgacctgacaccatgttgggagttgtgtgtggggctcttcatgtggca gatgtgagcctgcggaacagcatctctaacttccttcactctttagaaaggggtcaagtc ctacctgctcatacacttctgaacacagtcgatgttgaacttatctacgatggaatcaag tatgtacttaaggtaactcgacagtctcccaactcctatgtggtgatcatgaatggctca tgtgtggaagtagatgtccaccgtctgagtgacggaggactgctcttgtcctatgatggc agtagttataccacatacatgaaggaggaagtggataggtatcgcatcacgattggcaat aagacctgtgtgtttgagaaagaaaatgacccatcagtgatgcgctcaccttctgctgga aagttaatcaagtacattgtggaggacggaggccatgtgttttctggccagtcctatgct gagattgaggtaatgaagatggtgatgaccttaacagctgcagaatctggctgcatccat tatgtcaagcgacctggagcagctcttgaccctggctgtgtaatagccaaaatgcagttg gacaaccccagcaaggttcagcaggctgagcttcacactggtagtctgccatggatccag agcacagcacttacaggcgagaagctccatcgagtgttccactgtgtcctggataatctg gtcaatgtaatgaatggatactgccttccagatcctttctttagcagcagggtaaaagac tgggttgagcggttgatgaaaaccctcagagatccctccctgcctctcctagaattgcaa gatatcatgaccagtgtctctggccgtatccccctcaatgtggagaagtcaatcaagaag gaaatggctcagtatgctagcaacatcacatcagttctctgtcagtttcccagccagcag attgccaacatcctagatagtcatgcagctacattgaaccggaaatctgaacgagaagtt ttctttatgaacactcagagcattgttcagctagtgcaaagataccgaagtggcatccga ggccacatgaaggcggtggtgatggatctgctccggcagtacctgcgagtagagacacaa ttccagaatggtcactatgacaaatgtgtgtttgcccttcgggaagagaacaaaagtgac atgaacactgtactgaactacatcttctctcatgctcaagtcaccaaaaagaatcttctg gtcacaatgcttattgatcagttatgtggccgggaccctactctcactgatgagctgctg actatcctcactgaactaactcaactcagtaagactaccaatgctaaagtggcacttcgg gcccgtcaggttcttattgcctcccatttgccatcttatgagcttcgccataaccaagta gagtctatcttcctatcagctattgacatgtacggacatcagttttgcattgagaatctg cagaaactcatcctatctgaaacttctatctttgatgtcctaccaaacttcttctatcac agcaaccaggtagtgaggatggcagctctggaggtatatgttcgaagagcttatattgcc tatgaacttaacagtgtacagcaccgccagcttaaggataatacctgtgtggtggaattt cagtttatgctacccacgtctcatccaaacagagggaacatccccacgctaaacagaatg tccttctcctccaacctcaaccactatggcatgactcatgtagctagtgtcagcgatgtg ctgttggacaactccttcactccaccatgtcagcgaatgggtggaatggtctcttttcga acttttgaagattttgtcaggatctttgatgaagtgatgggctgcttctgtgactcccca ccccaaagccccacatttccagaggcaggccatacatctttatatgatgaagacaaggtc cccagggatgaaccaattcacattctgaatgtggccatcaagactgactgtgatattgag gatgacagtctggcagctatgttcagagagtttacccagcaaaataaagctaccctggtt gaccatgggattcggcgccttactttcctggttgcacaaaaggatttcagaaaacaagtc aactgtgaggtggatcagagatttcatagagaattccctaaattttttacgttccgagca agagataagtttgaagaggatcgtatctatcgtcacctggagcctgctctggctttccaa ttagagctgaaccggatgagaaattttgaccttactgccattccttgtgctaatcacaag atgcacctgtatcttggggcagccaaggtagaagtgggcacagaagtgacagactacagg ttctttgttcgtgcaattatcagacattctgatctggtcactaaggaagcttcttttgaa tatctacaaaatgaaggggagcggctactgctggaagccatggatgagttagaagttgct tttaataatacaaatgtccgcactgactgtaaccacatcttcctcaacttcgtgcccaca gtcatcatggacccatcaaagattgaggaatctgtgcggagcatggtaatgcgctatgga agccggttgtggaaattgcgcgtcctccaggcagaactgaaaatcaacattcgcctgaca ccaactggaaaagcaattcccatccgcctcttcctgacaaacgagtctggctattacttg gacatcagcctatacaaggaagtaactgactccaggacagcacagatcatgtttcaggca tatggagataaacagggaccgctacatggaatgttaatcaatactccatatgtgactaaa gacctccttcagtcaaagagatttcaggctcagtccttaggaacaacatatatatatgat attccagagatgtttcggcagtccctgatcaaactctgggaatctatgtccactcaagca ttccttccatcaccccctctgccttctgacatgctgacatatactgaactggtgttggat gatcaaggtcagctggtccacatgaacaggcttccaggaggaaatgagattggcatggta gcttggaaaatgatcctgaaaagtcctgaatatccagagggccgggatatcattgttatt ggtaatgacatcacatacctaattgggtcctttgggccccaggaggatttgctgtttctc agagcttctgaacttgccagggcagagggtattccacgcatctatgtagcagccaacagt ggagcaagaattggactggcagaagaaattcgccatatgtttcatgtggcctgggtagat cctgaggatccttacaagggatacaagtatttatatctgacccctcaagattataagaga gtcagtgctctcaactctgtccactgtgaacatgtggaggatgaaggagaatccaggtac aagataacagatattattgggaaagaagaagggcttggagcagagaaccttcgaggttca ggaataattgctggagaatcttcattggcctatgatgagatcatcaccatcagcctggtg acatgccgggccattggaattggggcttatcttgttcggctgggacagagaaccatccag gttgagaactctcacttaattttgacaggagctggtgccctcaacaaagtccttgggcgg gaagtatatacctccaataaccagcttgggggcatccagatcatgcacaataatggagtg acccacagcactgtttgtgatgactttgaaggagtcttcactgtcttgcactggctgtca tatatgcctaagagtgtgcacagttcagttcctctcctcaactccaaggatcctatagac agaatcatcgagttcgtccctacaaaggccccttatgatcctcggtggatgctagcaggt cgtcctcatccaacccagaaaggtcagtggttgagtggattttttgactatggatctttc tcagagattatgcagccatgggcacaaactgtggtggttggtagagccaggctaggagga atacctatgggtgtagttgctgtagaaacccgaacagtagaactaagtatcccagctgat ccagcaaacctggattctgaagccaagataattcagcaagctggccaggtttggtttcca gactctgcatttaagacctatcaggctatcaaggacttcaaccgtgaaggactgcctttg atggtatttgccaactggagaggcttctctggtgggatgaaagatatgtatgaccaagtg ctgaagtttggggcttacatcgtggatggcttgcgggaatgctcccagccagtgatggtt tacattcctccccaggctgagcttcggggtggctcctgggttgtgattgaccccaccatc aaccctcggcacatggagatgtatgctgaccgagaaagcaggggatcagttctggagcca gaagggacagtagaaatcaaattccgcaaaaaggatctggtgaaaaccatgcgtagggtg gacccagtctacatccgcttggctgagcgattgggcaccccagagctaagcccagtggag cggaaggagctggagaacaagctgaaggagcgggaggaattcctaattcccatttaccat caggtagccgtgcagtttgctgacttgcacgacacaccaggccggatgcaggagaagggt gttattaatgacatcctggactggaaaacatcccgcaccttcttctactggcggctgagg cgtctcctgctggaggacctggtcaagaagaaaatccacaatgctaaccctgagctgact gatggccagatccaggccatgttgaggcgctggtttgtggaagtggaaggaacagtgaag gcctacgtttgggacaataataaagatctggtggagtggctggaaaagcagctgacagag gaagatggtgttcgctcagtagtcgaggagaacatcaaatacatcagcagagactacgtc ctcaagcagatccgcagcttggtacaagccaatccagaagttgccatggattccatcgtc catatgacccagcacatctcacccactcagcgggcagaaattgtacggatcctctccaca atggattccccttccacatag

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