Heterocephalus glaber (naked mole-rat): 101717399 Help Entry 101717399         CDS       T02812                                  Symbol Acacb Name (RefSeq) acetyl-CoA carboxylase beta   KO K01946   acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15] Organism hgl  Heterocephalus glaber (naked mole-rat) Pathway hgl00061   Fatty acid biosynthesis hgl00620   Pyruvate metabolism hgl00640   Propanoate metabolism hgl01100   Metabolic pathways hgl04152   AMPK signaling pathway hgl04910   Insulin signaling pathway hgl04920   Adipocytokine signaling pathway hgl04922   Glucagon signaling pathway hgl04931   Insulin resistance hgl04936   Alcoholic liver disease Brite KEGG Orthology (KO) [BR:hgl00001]  09100 Metabolism   09101 Carbohydrate metabolism    00620 Pyruvate metabolism     101717399 (Acacb)    00640 Propanoate metabolism     101717399 (Acacb)   09103 Lipid metabolism    00061 Fatty acid biosynthesis     101717399 (Acacb)   09110 Biosynthesis of other secondary metabolites    00254 Aflatoxin biosynthesis     101717399 (Acacb)  09130 Environmental Information Processing   09132 Signal transduction    04152 AMPK signaling pathway     101717399 (Acacb)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     101717399 (Acacb)    04922 Glucagon signaling pathway     101717399 (Acacb)    04920 Adipocytokine signaling pathway     101717399 (Acacb)  09160 Human Diseases   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     101717399 (Acacb)    04931 Insulin resistance     101717399 (Acacb) Enzymes [BR:hgl01000]  2. Transferases   2.1  Transferring one-carbon groups    2.1.3  Carboxy- and carbamoyltransferases     2.1.3.15  acetyl-CoA carboxytransferase      101717399 (Acacb)  6. Ligases   6.3  Forming carbon-nitrogen bonds    6.3.4  Other carbon-nitrogen ligases     6.3.4.14  biotin carboxylase      101717399 (Acacb)   6.4  Forming carbon-carbon bonds    6.4.1  Ligases that form carbon-carbon bonds (only sub-subclass identified to date)     6.4.1.2  acetyl-CoA carboxylase      101717399 (Acacb) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  ACC_central Carboxyl_trans CPSase_L_D2 ACCA_BT Biotin_carb_N Biotin_carb_C Biotin_lipoyl ATP-grasp Dala_Dala_lig_C ATP-grasp_3 Motif Other DBs NCBI-GeneID:  101717399 NCBI-ProteinID:  XP_004843694 UniProt:  A0A0P6K3R0 LinkDB All DBs Position Un AA seq 2434 aa AA seqDB search MVLLLFLSCLIFSCLTFLKIWEKMTEPKPVTNSNLEVSFSADQETFPASDSSEEPLQMNS SHSSSPLDTPNQAEPASHKDPGYARPQRNSLPFSHQKPPRNPASSSDTWPSPERQDNGKG AYLSRENERQAHIKRQMMTNFIVGSFDDCSSDEDPGAGLFRESSRKGSRASLGNLSPEAA PISGEPETHPPTMRPSMSGLHLVKRGREHKKLDLHRDFTVASPAEFVTRFGGDRVIEKVL IANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADQYVPVPGGP NNNNYANVELIIDIAKRIPVQAVWAGWGHASENPKLPELLCKHGIAFLGPPSEAMWALGD KIASTIVAQTLDIPTLPWSGSGLTVEWAEEDLQQGKQISVPEDVYNGGCVKDVDEGLEAA EKIGFPLMIKASEGGGGKGIRKAERAEDFPMLFRQVQSEVPGSPIFLMKLAQHARHLEVQ VLADQYGNAMSLFGRDCSIQRRHQKIIEEAPATIATPAVFEFMEQCAVRLAKTVGYVSAG TVEYLYSQDGSFYFLELNPRLQVEHPCTEMIADINLPAAQLQISMGVPLHRLKDIRLLYG ESPWGVTPIYFEAPSNPPLARGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYF SVAATGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLINLLETE SFQNNDIDTGWLDHLIAQKVQAEKPDVMLGVVCGSLNVADTMFRTCMTDFLHSLERGQVL PADSLLNIVDVELIYGGVKYILKVARQSLTMFILIMNGSYIEIDAHQLNDGGLLLSYNGS SYTTYMKEEVDSYRITIGNKTCVFEKENDLTVLRSLTAGKLIQYTVEDGGHVEAGRSYAE IEVMKMIMTLVVPESGLVKYIKRPGALLEAGCMVARLELDDPSKVHSAKPFMGVLPAQQT LPILGEKLHQVFHSVLDNLTNVMSGYCLPEPFFSIKLKEWVEKLMMTLRHPSLPLLELQE IMTSVAGRIPVPVEKAVRRVMAQYASNITSVLCQFPSQQIATILDCHAATLQRKADREVF FMNTQSIVQLVQRYRSGTRGYMKAVVLDLLRRYLQVEHHFQQAHFDKCVINLREQFKPDM SHVLNCIFSHAQVAKKNQLVIMLIDELCAPDPTLSEELTSILNELTQLSKTEHCKVALRA RQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCPENLKKLILSETTIFDVLPTFFYHA NKVVCMASLEVYVRRGYIAYELNSLQHRELPDGTCVVEFQFMLPSSHPNRMTVPISVTNP DLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEDFTRNFDEVISCFANVPRDIPVFSKACT TLYSEHNYKSLREEPIHILNVAIQCADHLEDEALVPIFRTFVQSKKNILVDYGLRRITFL IAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQLELSRMRNFDLTAVPCANHKMHLYL GAAKVNEGVEVTDHRFFIRAIIRHSDLITKEASFEYLQNEGERLLLEAMDELEVAFNNTS VRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAEVKINIRPATTDSA VPIRLFITNESGYYLDISLYKEVTDPRSGNIMFHSFGDKQGSLHGMLINTPYVTKDLLQA KRFQAQSLGTTYVYDFPEMFRQALFKLWGSPDKFPKDILTYTELVLDSQDQLVEMNRLPG SNEVGMVAFKMMLKTPEYPEGRHVIVISNDITYRIGSFGIREDMVYQRASELARARGIPK IYLAANSGARIGLADEIKPMFQVAWVDPENPHKGFKYLYLTPQDYTRISSLNTVHCKHIE EGGESRYVIIDIIGKEDGLGVENIKGSGMIARESSLAYDEIITISMVTCRSLGIGAYLVR LGQRVIQVENSHIILTGVRALNKVLGREVYSSNNQLGGVQIMHYNGVAHVTVPDDFEGVY TILEWLSYMPKDIHSPLPIITPTDPIDREIEFYPSRVPYDPRWMLAGRPHPTLKGTWQSG FFDQGSFKEIMAPWAPTVVVGRARLGGVPVGVIATETRTVEVAIPADPANLDSEAKIFQQ AGQVWFPDSAYKTAQAIKDFNREKLPLVVFANWRGFSGGMKDMYDQVLKFGSYIVDGLRQ YQQPILIYLPPYAELRGGSWVVLDTTINPLCIEMYADKESRGGILEPEGTVEIKFRKKEL VKTVRRIDPTSRKLVARLGSSQLSDKDRKDLEGQLKAREELLLPIYHQVAVQFAELHDTP GRMLEKGAISDVLEWRTARTFLYWRLRRLLLEDRVKQEILRASGELSHEHMESMLRRWFV ESEGAVKAYLWDNNQVVVQWLEQQWQEGDSPRSAIWENIKYLKRDAVLKTIRSLVQENPE VAMDSMVYLSQLISPGERLQVAQLLSTMDSPAST NT seq 7305 nt NT seq  +upstreamnt  +downstreamnt atggtccttctcctttttctatcttgcctgattttctcctgcctgaccttcttaaaaatc tgggagaaaatgacggagcccaaaccagtgaccaacagtaacttggaagtgagcttcagc gcggaccaggagacctttccagcctcagacagttcagaagagccattgcaaatgaacagc agccatagcagctcacctctagatactcctaaccaggcagagccagcctcccacaaagac cccggatatgcccgtccacagagaaactccctgccgttctcacaccagaagcccccaaga aaccctgcttcttccagtgacacatggccttccccagaacgtcaagacaatgggaaaggt gcttacctctccagagagaacgagaggcaggcacacatcaagaggcagatgatgaccaac ttcatcgtgggctcctttgatgactgctcctctgatgaagaccccggagctggcttgttt cgagaatcttcccggaaaggcagccgggccagcttgggcaacctgtctccagaggcagct cccatctctggggaacctgagacacaccccccaactatgagaccaagcatgtcggggctc cacctggtgaagaggggccgggaacacaagaagctggacctgcacagagacttcaccgtg gcttccccagccgagtttgtcacacgctttgggggtgatcgggtcatcgagaaggtgctc attgccaacaacgggatcgccgccgtgaagtgcatgcgctccatccgcaggtgggcctac gagatgttccgcaatgagcgagccattcgctttgtagtcatggtgacccctgaggacctc aaggccaacgcagagtacatcaagatggcagatcagtacgtccccgtcccaggagggccc aacaacaacaactatgccaacgtggagctgatcatagacatcgccaagagaatacctgtg caggcagtatgggctggctggggccatgcttcagaaaatcccaagcttccagagctgctg tgcaagcacgggattgcgttcttaggaccccccagtgaggctatgtgggccttgggagat aagatcgcctccaccattgtggctcagaccctcgacattccaactctgccctggagcgga agtggtctgacagtggagtgggcagaggaggatctgcagcaggggaaacaaatcagtgtc ccagaagatgtttacaatggaggttgtgtgaaagatgtcgatgaaggcttggaggcagca gaaaaaattggttttccactgatgatcaaagcttctgaaggtggtggagggaaaggaata cggaaggctgagagagctgaggatttccccatgcttttccgacaagtgcagagtgaagtc ccaggctcacccatctttctcatgaagctggcccagcatgcccggcacctggaggtccag gtcctggctgaccagtacggtaatgctatgtcactgtttgggcgagactgctccatccag cggcgacatcagaagatcatcgaggaggcaccagccaccatcgccacaccagctgtgttt gagttcatggagcagtgtgctgtccgtctggccaagaccgtgggctacgtgagcgcaggg acagttgaatacctctacagccaggatggcagcttctacttcttggagttgaatcctcgc ctgcaggtggagcatccctgcacagaaatgattgctgacatcaacctgccagctgcccag ctacagatttccatgggtgtgccactacacaggctgaaggacatccggctcctgtatgga gagtcaccatggggggtgacacccatttattttgaagccccttcaaaccctcccctcgcc cgtggccatgtcattgcggccagaatcaccagcgaaaatccagatgaggggtttaagcca agctctgggacagtccaggaattgaatttccgcagcaacaagaatgtgtggggttacttc agtgtggctgccacaggaggcttacatgagttcgctgattcccagtttgggcactgcttc tcctggggcgagaaccgggaggaggccatttcgaacatggtggtggctttgaaggaactg tctatccggggtgacttccggaccactgtggaatatctcattaacctcctggagaccgag agcttccagaacaacgacatcgacaccggctggttggaccacctcatcgcacagaaagtg caggcggagaagccggacgtcatgctcggggtggtgtgcgggtccttgaacgtggcagat acgatgttcagaacatgcatgacggatttcttgcactccctggaaaggggccaggtcctc ccagcggattctctgctgaacattgtagatgtggagttgatttacggaggagtcaagtac attctcaaggtggcccggcagtctctgaccatgttcatcctcatcatgaatggcagctat attgaaatcgacgcccaccagctgaatgatggggggttgctgttgtcctacaatggcagc agctacaccacgtacatgaaggaagaggtggacagttaccgaatcaccattggcaacaag acatgcgtgtttgagaaggagaacgatcttacggtcctgaggtccctaacggcagggaag ctgatacagtacacagtggaggacgggggccatgttgaagcagggagaagctacgctgag atagaggtgatgaagatgatcatgaccctagtcgtgccagagagtggcctagtgaagtac atcaagcgcccgggagccttgctggaagccggctgcatggtggccaggctggagctcgac gacccctctaaagtgcattcggccaagcctttcatgggggtgctccctgcccagcagacc ctgcccatccttggagagaagctgcaccaggtcttccacagtgtcctggacaacctgacc aacgtcatgagcggctactgcctgcctgagcctttttttagtataaagctgaaagagtgg gtggagaagctcatgatgactctccgacacccttctctgccgctgctggagctgcaggaa atcatgaccagtgtggcaggccgcattcctgtccctgtggagaaggcggtccgcagggta atggcccagtacgccagcaacatcacctcggtcctctgccagttccccagccagcagata gccaccatcctggactgccatgcggccactctgcagcggaaggccgaccgtgaagtcttc ttcatgaatacacagagcattgtgcagttggtccagaggtaccgaagtgggacccgtggc tatatgaaagctgtggtgctggatcttctgcgaagatatttgcaagtcgagcaccatttc caacaagcgcactttgacaagtgtgtgataaacctcagggagcagttcaagcccgacatg tcccacgtgctgaactgcatcttctcgcatgcccaggtggccaagaagaaccagcttgtg atcatgctgatcgatgagctctgtgccccggatcctaccctgtcagaggagctgacctcc atcctcaatgagctcactcagctgagcaagactgaacactgcaaagtggctctcagagcc agacaggtcctgattgcctcccacctcccctcctatgagctgaggcacaaccaggtggag tccatcttcctgtctgccattgacatgtatggccaccagttctgcccagaaaacctgaag aaattgatactttccgaaaccaccatatttgatgtgctgcccactttcttctaccatgct aacaaggttgtctgcatggcgtcactggaggtttacgtgcggaggggctacatcgcctat gagctaaacagcctgcagcaccgtgagctcccggatggcacctgcgtagtggagttccag ttcatgctgccctcttcccatccaaaccggatgacagtgcccatcagtgtcaccaaccct gacctgctgaggcacagcacggaactcttcatggacagcggcttctccccactgtgccag cgcatgggggccatggttgccttcaggagatttgaggatttcaccaggaactttgatgaa gtcatctcttgcttcgccaatgtgcccagagacatcccagtcttcagcaaggcctgtacc accctgtactctgagcacaactacaagagcctccgagaagagcccattcacatcctgaat gtggccatccagtgtgcagaccacctggaggacgaggcgctggtgccgattttccggacg tttgtacaatctaagaaaaatatccttgtggattatggactccgaagaatcacattcctt attgcccaagagaaagaatttcccaagtttttcacattcagagcaagagatgagtttgca gaagatcgcatttaccgtcacttggagcctgctctggccttccagctggagctcagccgg atgcgcaactttgacctgactgctgtgccctgtgccaaccacaagatgcacctttacctg ggcgctgccaaggtcaatgaaggagtggaagtgacagaccacaggttcttcatccgtgcc atcatccggcactcagacctgattacaaaggaagcctccttcgagtacctgcagaatgag ggtgagcggctgctcctggaggccatggacgagctggaggtggcattcaacaacacaagt gtgcgcacagactgcaaccacatcttcctcaacttcgtgcctaccgtcatcatggacccc tccaagatcgaggagtctgtgcgctccatggttatgcgctatggtagccggttgtggaaa ctccgagtgctgcaggccgaggtcaagatcaatatacggccagccaccaccgacagcgct gtacccatccgcctgtttatcaccaatgagtcgggctactacctggatatcagcctctac aaagaagtgactgaccccagatctggaaacatcatgtttcactccttcggggacaagcaa ggaagcctgcatgggatgctgatcaacacaccctatgtcaccaaggatctacttcaggct aagcgatttcaggcacagtccctgggcaccacctatgtgtacgacttcccagaaatgttc agacaggctctctttaaactgtggggctccccagacaagtttcccaaagacatcttgaca tatactgagttagtgctggactctcaggaccagttggtggagatgaatcgacttcctggc agcaatgaggtaggcatggtggctttcaaaatgatgcttaagactccagagtatccggaa gggcggcatgtgatcgtcatcagcaatgacataacctaccgcattggatccttcggcata cgggaggacatggtgtaccagcgggcatcagagctggcccgggcacggggcatccccaaa atctacctggcagccaacagcggggcccgaattggcctggcagatgaaatcaaacccatg ttccaggtggcctgggtggacccagagaacccacacaaaggatttaaatacctgtacctg actccccaagactacaccagaatcagttccctgaacactgtccactgcaaacacattgaa gaaggaggagaatccaggtatgtcatcatagacatcattgggaaagaagatggcttgggt gtggagaacattaagggctcaggcatgattgccagggagtcctccttggcttacgatgag atcatcaccatcagcatggtgacctgccgctccctgggaatcggggcctatctggtgagg ctaggccagcgggtgatccaggtggaaaactcccatatcatcctcacaggagtacgagct cttaacaaggtcctgggaagagaggtctactcgtccaacaaccagctgggtggtgtacag atcatgcattacaacggcgtcgcccatgtcactgtgccggatgactttgagggggtgtac accatcctagagtggctgtcttatatgccaaaggatattcacagccccctccctatcatc acacccactgaccccatcgacagagaaattgagttttatccatccagagtgccctatgac cctcggtggatgcttgcaggaaggcctcacccaacactgaagggtacctggcagagcgga ttcttcgaccagggaagtttcaaggaaatcatggcaccctgggccccaaccgtggttgta ggacgagccaggctggggggcgtccctgtgggcgtgatcgccacagaaacacggaccgtg gaggtggcgatccctgccgaccctgccaacctggattctgaggccaagatattccagcag gcaggccaggtgtggttccctgactcagcctacaagacagcccaggccatcaaggacttc aaccgggagaagctgcccctggtggtctttgccaactggagggggttctctgggggcatg aaagacatgtatgaccaggtgctgaaatttggatcctacattgtggacggcctccggcag taccaacagcccatcctgatctacctcccaccctatgcagagctccgtgggggctcctgg gtggtcctggacaccaccatcaaccccctgtgcatagagatgtatgcggacaaagagagc aggggcgggattctggagcccgagggaacggtggagattaagttccgaaagaaagagctt gtgaagaccgtgaggaggatcgacccgacctcccggaagctcgtggcgcggctcgggtcg tcccagctgtcggacaaagatcgcaaggacctggagggccagctgaaggcccgcgaggag ctgctccttcccatctaccaccaggtggcagtgcagtttgcggaactgcacgacacacca ggccggatgctggagaaaggcgccatctctgatgtactggagtggaggacagcgcgaacc ttcctgtattggcgcctgcgccggctcctcctggaggatcgggtcaagcaggagatcctc cgggccagcggcgagctgagccatgagcacatggagtccatgctgcgccgctggttcgtg gagtctgaaggcgctgtcaaggcctacctgtgggacaataaccaggtggtggtgcagtgg ctggagcagcaatggcaggagggtgacagcccccgctcggccatttgggagaatatcaaa tacctgaagcgagatgctgtcctcaagaccatccgcagtctggtccaggaaaacccagag gtggccatggactccatggtgtacctgagtcagctcatcagcccaggggagcggctccag gtggctcagctgctgtccaccatggacagcccggcctctacctga

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