Heterocephalus glaber (naked mole-rat): 101720879 Help Entry 101720879         CDS       T02812                                  Symbol Sphk2 Name (RefSeq) sphingosine kinase 2   KO K04718   sphingosine kinase [EC:2.7.1.91] Organism hgl  Heterocephalus glaber (naked mole-rat) Pathway hgl00600   Sphingolipid metabolism hgl01100   Metabolic pathways hgl04020   Calcium signaling pathway hgl04071   Sphingolipid signaling pathway hgl04072   Phospholipase D signaling pathway hgl04148   Efferocytosis hgl04370   VEGF signaling pathway hgl04371   Apelin signaling pathway hgl04666   Fc gamma R-mediated phagocytosis hgl05152   Tuberculosis Module hgl_M00100   Sphingosine degradation Brite KEGG Orthology (KO) [BR:hgl00001]  09100 Metabolism   09103 Lipid metabolism    00600 Sphingolipid metabolism     101720879 (Sphk2)  09130 Environmental Information Processing   09132 Signal transduction    04370 VEGF signaling pathway     101720879 (Sphk2)    04371 Apelin signaling pathway     101720879 (Sphk2)    04020 Calcium signaling pathway     101720879 (Sphk2)    04072 Phospholipase D signaling pathway     101720879 (Sphk2)    04071 Sphingolipid signaling pathway     101720879 (Sphk2)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     101720879 (Sphk2)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     101720879 (Sphk2)  09160 Human Diseases   09171 Infectious disease: bacterial    05152 Tuberculosis     101720879 (Sphk2) Enzymes [BR:hgl01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.91  sphingosine kinase      101720879 (Sphk2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  DAGK_cat YegS_C Motif Other DBs NCBI-GeneID:  101720879 NCBI-ProteinID:  XP_004867047 LinkDB All DBs Position Un AA seq 652 aa AA seqDB search MNQHLESEEQWNQRPEQQVTRSWGHRPRRALDRAEAMAPPPATLAASTPLLHGEFGSYPA RGSRFALTLTSQALHIQRLLPKPEARPRDGLVPLSVISGCCTLRSHSPSDSAAYLCIYTY LWGRRGRRRAARTFQADGAATYEENRAEAQRWVTALMSLLRGLPLPGEGEISPELLPRPP RLLLLVNPFGGRGQAWQWCENHVLPMISEAGLSFNLIQTERHNHARELVQGLSLSEWDGI VTLSGDGLFCEVLNGLLDRPDWEQAVKMPLGILPCGSGNALAGAVNRHGGFAPALGLDLL LNCSLLLCRGGSHPLDLLSVTLASGSRCFSFLSVAWGFVSDVDIQSERFRALGRARFTLG TVLGLATLRTYHGRLSYLPAAVESASPGPANGLPRAKSELALAPAPAPPTDHSPLHRSVS DLPLPLPQPALTSPGSPDPLPVLSFNGGAPELAGDWGGTGEAPLSPDPLLPSPSGSPKAA PLSPITEGPPEMPAASGFPPHTTAAPVASAGGPQDHLLPPLGTPLPPGWVTVEGDFVLVL ALSPSHLGADLLAVPHASFDDGVVHLLWVRAGISRAMLLRLFLAMERGSHFNLGCPHVGY APARAFRLEPLTPRGMLTVDGELVEYGPLQGQIHPGLGTLLTGPPGHTGQGP NT seq 1959 nt NT seq  +upstreamnt  +downstreamnt atgaaccaacaccttgaatcagaggagcagtggaaccagagaccggagcagcaggtcacc aggagttggggccacaggcctaggagagccctggatagggctgaggccatggccccccca ccagcaacactggctgccagcaccccgctcctgcatggcgaatttggctcctacccagcc cgaggctcacgatttgccctcaccctcacatcacaggccctgcacatacagcggctgctc ccaaagcccgaagcccggccccgggatggcctggtccccctgtctgtgatctcaggctgc tgcaccctgcgaagccacagcccctcagactcggcagcctacttatgcatctatacctac ctgtggggccgtcgaggccgccgcagagccgcccgcacctttcaggccgatggggctgca acctatgaggagaaccgtgcggaggcccagcgctgggtcactgccctcatgagtctgctc cgaggattgcccctgcctggggaaggggagatcagccctgagctcctgccacggccaccc cggttgctactcttggtcaatccctttgggggacggggccaggcctggcagtggtgtgaa aaccatgtgctgcccatgatttccgaagctgggctgtccttcaacctcattcagacagag agacataaccatgcccgagagctggtccaggggctgagcctgagtgagtgggatggcatc gtcaccctctcaggagacgggctgttctgtgaggtgctgaacggactcctggatcgccca gactgggagcaggcagtgaagatgcccctggggattctcccctgtggctcgggcaacgca ctggctggagccgtgaacaggcatggggggtttgcaccagcgctgggcctggacctgctg ctcaactgctccctgctgctctgccgtggtggcagccatccactggacctgctctctgtg acgctggcctcaggctcccgctgtttctccttcctgtctgtggcctggggctttgtgtca gatgtggacatccagagtgagcgcttcagagccctaggcagagcccgattcaccctgggc acagtgctgggccttgccacattgcgcacctaccatggacgcctctcctacctccctgct gctgtggagtcagcctcacctggtcctgccaacggcctgccccgggccaagtcagagctg gccctggccccagctccagccccgcccacagaccactcccctttgcatcgctcagtgtct gacctgcccctgcccttgcctcagcctgccttgacctcccctggctcacctgatccctta cctgtgctgtccttcaacggtggggccccagagctggctggggactggggtggcactggg gaagctccactgtccccagacccactcctgccctcgccctctggctcccccaaggcagct ccactctctcccatcacagaagggcccccagaaatgcctgcagcctctgggtttccaccc cacaccaccgctgcaccagtagcctctgccgggggcccacaggaccacttgttacctcca ttgggcaccccgctgcccccaggctgggtgacagtggagggagactttgtgctggtgttg gcgctctctcccagccacctgggtgccgatctgctggcggttccccacgcaagctttgac gacggcgtggtacacctgctgtgggtgagggcaggaatctcgagggccatgctgctgcgc ctattcctggccatggagcgggggagccatttcaatttgggctgcccgcatgtcggctat gccccggcccgtgcgttccgcctggagccactcacgccccgaggcatgctcacagtggac ggggagctggtggagtatgggccgctgcaagggcagatacacccaggcctcggtacgctg ctcacagggcctcctggccacaccgggcagggaccctga

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