KEGG T02812: 101726130

Heterocephalus glaber (naked mole-rat): 101726130

Entry

101726130         CDS       T02812

Symbol

Hsd17b8

Name

(RefSeq) hydroxysteroid 17-beta dehydrogenase 8

K13370

17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) / 3-oxoacyl-[acyl-carrier protein] reductase alpha subunit [EC:1.1.1.62 1.1.1.239]

Organism

hgl Heterocephalus glaber (naked mole-rat)

Pathway

hgl00061

Fatty acid biosynthesis

hgl00140

Steroid hormone biosynthesis

hgl01100

Metabolic pathways

hgl01212

Fatty acid metabolism

Module

hgl_M00976

C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone

Brite

KEGG Orthology (KO) [BR:hgl00001]
09100 Metabolism
  09103 Lipid metabolism
   00061 Fatty acid biosynthesis
    101726130 (Hsd17b8)
   00140 Steroid hormone biosynthesis
    101726130 (Hsd17b8)
Enzymes [BR:hgl01000]
1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.62  17beta-estradiol 17-dehydrogenase
     101726130 (Hsd17b8)
    1.1.1.239  3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
     101726130 (Hsd17b8)

SSDB

Motif

Pfam:

adh_short_C2 adh_short KR Epimerase RNA_pol_Rpb1_4 RmlD_sub_bind

Other DBs

NCBI-GeneID:

101726130

NCBI-ProteinID:

XP_004846893

LinkDB

Position

AA seq 259 aa
MTTQLRLRSALALVTGAGSGIGRAVCARLAREGATVAACDLNGAAAHETVQLLEGPGSAQ
GAPRGNHAAFQADVSEARAARSLLEQVQACFSRPPSVVVSSAGINQDEFLLHMSEDDWDK
VIAVNLKGTFLVTQAAAQALVSSGSHGSIINISSIVGKVGNMGQTNYVASKAGVIGLTQT
AARELGRHGIRCNSVLPGFMTTPMTQKIPQAVKDKVIGMIPMGHMGSPEDVADVVAFLAS
EDSGYITGASVEVTGGLWM

NT seq 780 nt +upstreamnt +downstreamnt
atgacgactcagctccggctccgctccgcgctggccctggtcacaggtgcgggcagcggc
atcggccgagcggtctgtgcgcgcctggccagagagggggccaccgtggccgcctgtgac
ctgaacggggcagcggcgcacgagacggtgcagctgctggaagggccggggagcgcgcaa
ggggcgccccgcgggaaccacgccgccttccaggctgacgtgtccgaggccagggcggcc
aggagcctgctggagcaagtgcaggcctgcttctctcgcccgccatctgtcgttgtgtcc
tctgccggcatcaaccaggatgagttcctgctccacatgtctgaggatgactgggacaaa
gtcatagctgtcaacctcaagggcaccttcctagtcactcaagctgcagcccaggccttg
gtgtccagtggtagtcatggctccatcatcaacatcagtagcatcgttggcaaggtgggg
aacatggggcagacaaactatgtggcatccaaagctggtgtgattgggctgactcagacc
gcagcccgggagcttggacgacatgggatccgctgtaactctgtcctcccagggttcatg
acaacacctatgactcagaaaattccacaggcagtaaaggacaaggtgatcggaatgatc
ccgatgggacacatggggagccctgaggatgtggcagatgtggttgctttcctggcatct
gaagacagtggatacatcacgggggcctcagtggaagtcactggaggcctttggatgtaa

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