Hyaena hyaena (striped hyena): 120222434 Help Entry 120222434         CDS       T07257                                  Symbol OBSCN Name (RefSeq) LOW QUALITY PROTEIN: obscurin   KO K17531   obscurin-RhoGEF [EC:2.7.11.1] Organism hhv  Hyaena hyaena (striped hyena) Pathway hhv04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:hhv00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     120222434 (OBSCN)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:hhv01001]     120222434 (OBSCN)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hhv04131]     120222434 (OBSCN) Enzymes [BR:hhv01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      120222434 (OBSCN) Protein kinases [BR:hhv01001]  Serine/threonine kinases: CAMK group   Trio family [OT]    120222434 (OBSCN) Membrane trafficking [BR:hhv04131]  Others   Rho GTPase associated proteins    Rho guanine nucleotide exchange factors (GEFs)     120222434 (OBSCN) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  I-set Ig_3 ig Ig_2 V-set Pkinase Ig_5 PK_Tyr_Ser-Thr Ig_4 Ig_6 C2-set_2 C1-set Izumo-Ig BiPBP_C fn3 RhoGEF PH IQ ABC1 DUF1722 Motif Other DBs NCBI-GeneID:  120222434 NCBI-ProteinID:  XP_039076191 LinkDB All DBs Position Unknown AA seq 8923 aa AA seqDB search MDHSFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVEAGARFRLAQD GDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAAYAEQAPHFLLRPTSIRV REGAEATFRCRVGGSPPMAVSWAKDGRRLGAPDAPRVRVEASGEASALRIQSVRPRDGGT YTVRAENPLGAASADAALTVDADPDAAPPGSSTAGLLAHLQRRREVMRAEGIPASPPGSG MRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVVEGRRHLVYEDAQENFVLKILFCKQ SDRGLYTCTASNLVGQTYSSVLVVVREPAVPFKRRLQDLEVQEKESATFQCEVQLPSTEA TWYKEETRLWASAKYGIEEAGTERRLTVRNVSADDDAVYICETTEGSRTVAELAVQGNLI RKLPRKTAVRVGDTAMFCVELARQEGPIRWLRNQEEVVAGGRVAITTEGTCHTLTISQCS LEDMGEVTFTAGDCRTSTQFFVSAPRRPPLHAPEAPVVKARTEFSVTLAWSPPPHGDLPV PIDGYLVEKKRLGAYAWSRCHKAEWVAEHKLTVANVAEEGDFQFRVSAVNSFGQSPYLEF PGTVHLAPQLAVKTPLKAVEAVEGGEVTFSVDLTLASAGEWFLDGQPLKASSVYVICHDG TRHALTIRSVSASLNGAELKFMANGIESSIRMEVRAAPGLTTKRPVAAVREVLARLHEEA QLLAELSDQAAAVTWLKDGHALPPGPKYEVQASAGQRALLVRDVVRDDAGLYECVSRGGR IAYQLLVQGLTPFLHKDTAGGFVDVVAGGPVHFECETSEAQVRVHWYKDGTELSGSSQRF LQEDVGTWHRLVAASVSRQDEGTYSCRVGEDSVDFQLRVHEPSAMFAKGQPACSAVQAKA GTSATLSCEVAQDKTEVTWYKDGKKLNASSKVHMEAKGCSRRLVVQQAGKADAGEYSCEA GGEKVSFHLDVTEPVLVFAKGQPARSEVQTKVGASATLSCEMAQDKTEVTWYKDGKKLSA SSRVHVEAKGCSRRLVVQQAGKADVGEYSCEAGGQKVSFHLDVTEPSAMFAKGQPACSEV QAKLGASATLSCDVAQDKMEVTWYKDGKKLSASSRVCMEAKGCSRRLVVQQAGKADAGEY SCEAGGQKVSFRLDVTEPTTMFVKEQPAHSEVQAKPGASAMMSCEVAQDKTEVTWYKDGK KLSASSRVHVEAKGCSRRLVVQQAGKADAGEYSCEAGGQKVSFHLDVTEPAAMFAKGQPA HSEVQAKAGASATLNCEVAQDKTEVTWYKDGKKLSASSKVHVEAKGCSRRLVVQQAGKAD AGEYSCEAGGQKVSFRLDVTEPSAVFSKEQPAHSEVQAKAGASATLNCEVAQDKMEVTWY KDGKKLSASSKVHMEAKGCSRRLVVQQAGKVDAGEYSCEAKGQKVSFCLDVTEPSVVFSK EQPAHSEVQVNAGASATLNCEVAQDKMDVTWYKDGKKLSESSKVHMEAKGCSRRLVVQQA GKADAGEYSCEAGGQKVSFCLDVTEPVSMFAKEQLAHSEVQAKMGASAMLSCEVAQDKMD VTWYKDGKKLSESSKVHMEAKGCSRRLVVQQAGKADAGEYSCEAGGQKVSFCLDVREPSA VFSKEQPAHSEVQAKAGASATLNCEVAQDKMDVTWYKDGKKLSESSRVHMEAKGCSRRLV VQQAGKADAGEYSCEAGGQKVSFCLDVTEPTVVFAKEQPACSEVQAKAGASATLSCEVAQ AQTEVTWYKDGKKLSTSSKVHVEAKGCSRRLVVEQAGKADAGEYSCMANGQKVSFCLDVT EYSAVFAKEQPACSEVQAKAGASATMSCEVAQAQTEVTWYKDRKKLSASSRVHVEAKGCS RRLVVQQVGKADAGEYSCEAGDQKVSFHLDVTEPGACFKTSAMFAKGQPACSEVQTKVGA SATMSCEVAQDKTEVTWYKDGKKLSASSRVHMEAKGCSRRLVVQQAGKADAGEYSCEAGG QKVSFHLDVTEISAVFAKEQPAHSEVQAKAGASTTLSCEVAQEKTEVTWYKDGKKLSASS RVHVEAKGCSSRLVVQQAGKADTGEYSCEAGSQKVSFRLDVTELEPEAPTVERPGHKEPL VVKEHEDIVLTATLATPSVAAVRWFKDGVEIRRSKRHETTSLEDTHTLRIRRAQTLDTAV YSCRVGADGQDFPVQVEEVAAKFCRPLEPVRGELGRTVTLICELSPPQAEVVWHCGSTQL RASKRFQMEAAGPRRSLTVSDLRLEDAGEYACETRDDRTSAQLTVSAPRTVKFTPGLSAM VAEEGQEATFQCVVSPSDAAVMWFRDGASLQPSEKFLISQSGASHSLTILGLTLEDAGQI TAEAEGVSTAAPLRVREAPVLFRKKLEPQTVEEQSSVTMEVELTRPWPEVKWTRNATALA PGKNVEIHAESTRHRLVLQCVGFEDRGFYGCETPDDKTQAKLTVEMRQVRLVRGLQAAEA WEQGTATMEVELSHDHVEGSWTRDGVRLQPGPTCQLAVQGPIHTLTLLGLRPQDSGLIAF KAEGVHTSARLTVTELPVRFSRPLQDVVATEKDRVNLECELSRPNVDVRWLKDGVELRVG KTVGMVAQGTCRSLIIFHCELGDQGVYVCDARDAQSSASLKVQGRNVQIVTHLEDVEVME KEGATFSCKISHDEVPAQWFWEGNKLRPSDNVRIRQEGRTYTLIYRRVLAEDAGEIKFVA ENAESRAQLRVKELPVTILRPLRDKIAMEKHRGVLECQMSRASAQVQWFKGHVQLQPGPK YEMVSDGLYRKLIINDVQPEDEDIYTCDASDVKTSAQFFVEEQSITIVRVLQDVTVMEPA PAWFECETSIPSVRPPKWLLGKTVLQAGPTIGMEQEGTVHRLTLRRTCSTMTGPVHFTIG KSRSTARLVVSDIPMVLTWPLEPKSGREQQSVVLSCDFKPPPKAVQWYKEDTPLAPSDKY KMRLEGHMAELRILRLTPADAGVYRCQAGSAQSSAEVTVEAREVTVMKPMQDAEATEEGR ACFSCELSHEDEEVEWSLNGTPLYNDSFHEISHEGRRHTLVLKRVRRADAGLVRACSPKV SVTARLEVKAKPVVFLKALDDVSAEERGTLALQCEVSDPQAHVVWRKDGVELGPSDKYDF LHTAGTRGLVVHDLSRDDTGLYTCSVGSEETRARVSVHDLHVGITKRLKSAEVPEGQSCT FECVLSHENPGDVATWTVGGKTVGSSGRFRATLQGRKYTLVVQDAAPGDAGEVVFSVRDL TSKASLIVRERPAGITKPLEDQQATPGEDAVLSCELSRAGTSVRWLKDGKAIRKSQKYDL VTEGTRATLVVRAVSLKDSGEYTCETEASKSTASLRVEEKANRFTDELTDLQVEEKGTAV FLCKTERPATTVTWRKGLTELHASGKHTPSQEGLTLQLTISTLERADSDMYTCDIGQACS QARLLVQGRKVLITEDLEDVEVREGSSATFSCRISPADYGPVHWFLDKTPLHPNELNEIE VQPGGYHVLTLRQLALKDSGTVHFEAGDQRTSATLQVTEKPSVFSRELTEATVTEGEDLT LVCETTILDSPVCWTKDGKALRPSARCQLSQEGHRAQLVIKGTTVQDGGRYKCEAGGSWS SSIVRVHARPVWFREGLKDLEVPEGRAATLRCVLSSVAAPVEWRRGDEALRPGGKYSLRQ EGAVLELVVRDLRPQDTGQYSCHFGDQMTMAMLTVKALSAEFIGRLRSKEASEGATATLR CELSKEAPVEWKKGSQALRAGDRVSLRQDGTVCELEIRGLAVADAGEYSCVCGQERTSAT LTVRALPAEFIGRLRSKEASEGDTAMLHCELSKEAPVEWRKGSQTLRAGDRVSLRQDGTM CELEIHDLALADAGEYSCVCGQERTSATLTVRALPAKFTKNLRKEEAMEGATAMLRCELS KAVPVEWRKGSQILRAGDRVSLRQEGTMCELEIRGLAVADAGEYSCVCGQERTSATLTVR ALPAKFTKSLRKEEAVEGDMATLHCELSKAVPVEWRKGSETLRAGNRVTLRQEGTVCELE IRGLALADTGEYSCVCGQERTSAVLTVRALPAQFIQDLKTKEAMEGAMATPHCELSKAVP VEWRKGSKTLRAGDRVRLKQDRTVCELEIHGLVVSDAREYSCVCGQERTSATLTVRAMPA KFTKSLKKEEATEGTTAILRCELSKVAPVEWRKGSETLRTRDRMSLRQDGTVCELEIRDL ALVDAGEYSCVCGQERTLAMLTIRGLPPKFTKSLKKEEATEGATATLRCELSKAVPVEWR KGSETLRAGDRVSLKQDGTICELEIHGLIMEDAGEYSCVCGQERTSATLTVRALPAKFTK NLLKEEATEGATATLHCELSKVVPVEWRKGSETLRAGDRVSLKQDGTVCELEIHGLALED TGEYSCVCGQEKTSAMLTVMALPAKFTKSLGKEEATEGATAKLCCKLSKVAPVEWRKGSK TLRTGDRVSLRQDGTMCELEIHGLAVADAGEYSCVCGQESTSAMLTVRALPAKFTKSLRK EEATEGDTATLHCELSKAIPVEWRKGSETLRAGDRVSLKQEGTVCELEIHGLALEDTGEY SCVCGQERTSAMLTVRALPAKFTMSLRTEEATEGATAILRCELSKAVPVEWRKGTETLRA GERVSLKQDGTVCELEIGCLAMADAREYVCVCGQERTSATLSGVNTMCALPTKFTKNLLK EEAIEGAMATLRCELSKAVPVEWRKGSETLRAGNRISLRQDGTVCELQIRGLALADAGEY SCVCGQERTSATLSVRALPAKFTRSLRTEEATEGATAILLCELSKVAPVEWRKGSETLRA GDRVSLKQDGTMCELEIRGLAVADAGEYSCVCGQERTSAMLTVRAPQVVFKEPLQSMQAE EGASATLRCELSQPNAAVVWSKGGLELQADGRREPRQRGHTAELMLRDLRREDAGEYTCA CGPQATSAALTVTAAPVHFLRELQAQEVDEGATAHLRCELSREGASVEWRKDSLQLFPCA KYQMVQEGRAAELRVHGTEQEDAGHYTCDTGHAQSTASLSVRAPRPIFQMELQSTGQEAG SVARLHCQLSEAEPGVPVQWLKEGVELHMSPKYEIRRVGTTCELLIHGLETKDTGEYVCV AGGQKTVASVMVKEPEVTIVRGLEDAEVQVDGDVEFRCQLSRAGATEVEWRLQGLPLQNN EVTELAVQGGCTHTLRLKGVTPEDAGIVSFHVGAHTSSAQLTVRVPEVSILEPLQDVQLS EGQDAHFRCQLSRACGQEACWALGGVPLQANEMNDITVEHGTLHLLTLHKVTLEDAGTIS FQVGSCSSEAQLKVTAKNTVVRGLENVDALEGGEALFECQLSRPEVATHTWLLDDEPVRT SENAEVVYFENGLRHLLLLKNLRPQDSCRVTFLAGDVVTSAFLTVRGWRLEVLESPQDAA VRAGGQVRFRCTLSEAVPVGETTWYINGAAVQPDDPDWMVTADGSHHTLLLRGAQPHHAG EVTFAARDAVASARLTVLGLPDPPEDAEVVARSGRSVTLSWVAPASDGGGGLCGYRVEMK AVATGEWRLCHELVPGPECVVDGLAPGETYRFRVAAVGPAGAGEPVHLPQMVKLGEPPPP CLRPLPPAPPALESRQVAAGEDVFLECEVAEAGEVVWLKGTEVIQPSGRFQVLCQGQRQT LVIQSFSALDQGEYHCGHAGEQASSAAASFRVVLSPGSGDEAPAQPRLPPEAAQEGDLHL LWEALARKRRMSREPTLDSISELPEENGRSPRLQQEVEEAAPDLSEDYSTADELARTGEA DLSHTSSDDESRAGTPSLVTYLKKAGRTSTSPLASKLGIPAVGKPLKHQEQPTAGHPPPG DLRAADLGDPSMDKAAVKIQAAFKGYKVRKEMKQQEGPVFSRTFGDTEAQVGDVLRLECV VSSKADVRARWLKDGMELTDSRHHHIDQLGDGTCCLLVTGLGRGDAGRYTCQVSSKFGRV AHSACVVVSGTESEAESSSGGELDDAFRRAARRLHRLFRTKGPAEVSDEEIFLSADEGPA EPEEPADWRTYREEEHFVYIRFEALAEAHRAATCFREMFGTMGIGVDISLLEQGPRGVEM RISKVAPAPVTAQEVVPRPLTSEAAPVFLTELQNQEVQDGYPVSFDCVVTGQPVPTVCWF KDGRMLEEDDHYMISEDQQGGHQLIITAVVPADMGVYRCMAENSMGVSSTKAELRVDLTS TDYETAADATETSSYFSAQGYLSSREQEGTESTSEEGQLPQVVEELKDLQVAPGTRLAKF QLKVKGYPAPRLYWFKDGQPLTASAHICMTDRKTLHTLEVVSVTREDAGQYSAYISNTVG AAYSSARLLVRGPKDPEEKPASDVHQQLVPPRFLERFTSKKVKKGSSITFSVKVEGCPAP AVHWLREEAERGVLWIGRDTPGYTVASSAQQHSLVLLDVSRQHRGTYTCIASNAAGQALC SASLHISGLSKEAGAAEEHVGVKEALISTFLQGTQAVSTQMSEPTGFTDLAGQRKEPPVV EARGHLSLAEVGTEEFLQKLTSQITEIVSAKITQAKLQVPGGDSDEESKTPSASPWHGRS RPSSSVQESSSESEDGDSRGEIFDIYVVTADYLPLGAEQDAISLREGQYVEVLDSAHPLR WLVRTKPTKSSPSRQGWVSPAYLDRRLKLSPEWGPTEAPEFPGEAVSEDEYKTRLSSIIQ ELLNSEQAFVSKLQFLQSHHMQHLDCCPHVPAAVASQKAVIFRNVQDISHFHSSFQKELQ QCDTDDDVAMCFIKNQAAFEKYLEFLVGRVQAESAVVSTAVQEFYKKYTEEVLSAADPSQ PPPPPLQHFLEQPVERVQQYQALLKELIRNKARNRQNCALLEQAYAVVSALPQRAENQLH VSLMENYPGTLQALGEPIRQGHFIVWEGAPGARMPWKGHHRHVFLFRHHLVVCKPRRDSR TDTFSYVFRNMMKLSSIDLNDQVEGDDRAFEVWHEREDSVRKYLLQARTVITKNSWVKEI CGIQQRLVLPVWQPPDFEEELADCTAELGETVKLACRVTGTPKPIVSWYKDGKPVEVDPH HILIEDPDGSCALILDNLTGVDSGQYMCFAASAAGNASTLGKILVQVPPRFVKKVRAVPF VEGEDAQVTCTIEGAPHPQIRWYKDGALLTPSSKYRTLSEPRSGLLVLEILAASKDDLGH YECELVNRLGSARGGAELCMQSPAMRAREQRRREQLAAVEDVVAPPPVALETTDQEITSV PRTLVCPKAPGPSTGDHAGSSPGSRGAPKLQEAGPQLPGTEAADASGVLQKVPEPLPQEG QEQEVGAHAEAQGLTVPIRMEGTAWPGAGVVELWDIHSQVFTETKHRTYVYQASDTGATR PPSMQVTIEDVQAQRGSMAQFQAVIEGNPQPTVTWYRDDAQLVDGARLSQQQEGTTYSLV LRDVTQQDAGVYTCLAQNAGGQVLCKAELVVHGGDSQPDSEKQSYRRKLHSFYEVKEEIG RGVFGFVKRVQHKGNQMFCAAKFIPLRSRTRTQAYRERDILATLSHPLVTGLLDQFETRK TLILILELCSSEELLDRLFKKSVVTEAEVKVYIQQLVEGLQYLHSQSILHLDIKPPNILM VHHAREDIKICDFGFAQKITPEEPQYSKYGSPEFVSPEIIEQTPVSEASDIWAMGVISYL SLTCSSPFAGESDRATLLNVLEGRVSWSSPMAAHLSEDAQDFIKAALQRAPEARPSAAKC LAHPWFQKSIPAEEAHFINTKQLKFLLARSRWQRSLMSYKSILVMRSIPELLQGPPDSPS LGVARHLRGDASASSSSSSSSSDNELAPFARAKSLPPSPVTHSPLLHPRGFLRPSASLPE EAEACAPAAAAPPPASSPGAEGPAAPGCVPRQSVIRSLFYQQAGEAPERGGPAAGGRRHP ARRRHLLKGGYFARALPGLREPLLEHRTLEEEAAREEQAALLAKTPSFETALKLPGSSAR GAPCRSRSLELDRPHSPSSSAEACEGGQCPGPALSGLQTGESPPGGGTCAREIERPEGSW QEPRLLPSIGDHPGAAQQERSSQDSCAGQPAPSFHPQWGPAPLQGCGPPKAVTPQLSGSF PSEQCSGPQRASLSTFPLGDTQSPVFPAQESPQPGSMEGPKETRLPRRLSPPSSPGLASL VGMEPGPSQDTEVKALEPEDASEPEPSPQWPQEQATTRKFSLGWRGGYAGVAGYGTFAFG GDAGGMLGQGPLWARMAWATSQSSEEHDDAGAKSPPPQATAAPLPEGSGAPPRASPELSS WEDFGGGSQVSLVQIRDLSGDSEAADTVSLDISEVEPAYLNLSDLYDIKYLPFEFMIFRK VPKPVEAESPSSPESDAEEELAEFPETTWPWPGALGPPASLQITEEPEDMEALLTEATSS RKRKWSPPSGGLFHLPGRHALEEPLELGLRRRVRASVAHISRLLKGRPEGPEKESPPRKK AGLASFRLALKSRDRAPSFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESS GRLLISSTLKNFQLLTILVVTADDLGVYTCSMRNTLGTAATTAVLRKAERPLSSPRPDIG EVYADGVLLVWKPVESYGPVTYIVQCSLEGGSWNTLASDIFDCCYGASKLSRGGTYTFRT ACVSKAGMGPYSSPSEPVLLGGPSHLASEEESRAPRPGQPLPSTETFAFQMQIRRGRFSV VRQCREKASGRALAAKIVPYRPEDRTAVLREYEALKSLRHPHLAQLQAAYLSPRHLVLIL ELCSGPELLPCLAERVSYSESEVKDYLWQMLSAAQYLHAQRILHLDLRSENMIVTEYNLL KVVDLGNAQSLAQEKILPSERFKDYVETMAPELLEGQGAVPQTDIWAIGVTAFIMLSAEY PVNSEGTRDLQKALRKGLIRLSRCYAGLSGGAVAFLRSTLCAHAWGRPCASSCLQCPWLT EEGPAGSHPAAVSFPTTRLRAFVREREKKRALLYKKHNLAQVR NT seq 26772 nt NT seq  +upstreamnt  +downstreamnt atggatcactcattcagcggggcgccccgattcctgacccggcccaaggcctttgtggtg tcggtgggcaaggatgccactctgagttgccagatcgtgggcaaccctacgcctcaggtg agctgggagaaggaccagcagccggtggaggcgggcgctcgcttccgcctggcccaggac ggcgacctgtaccgcctcaccatcctggacctggccctgggcgacagcgggcagtatgtg tgccgtgcgcgcaacgccatcggcgaggccttcgcggctgtgggtctgcaggtggatgcc gaggccgcttacgccgagcaggcgccccatttcctgttgcggcccacgtccatccgagtg cgcgagggcgccgaggctaccttccgctgccgcgtgggcggctcgccgcccatggcagtg agctgggccaaggatgggcggcgcctgggcgcgcccgacgccccccgagtacgcgtggag gccagcggtgaggccagcgcgctgcgcatccagtccgtgcggccgcgcgacggcggcacg tacacggtgcgcgcggaaaaccctttgggcgccgctagcgccgacgccgcgcttacggtg gacgcggacccagatgctgccccgccagggtcctccacagccgggcttctggcgcacctg caacggcggcgggaggtgatgcgcgccgagggcatcccggcttcgccacccggctcaggc atgcgcacctgcacggtgactgaaggcaagcacgcgcgcctcagctgctacgtgacgggc gagcctaagccggaaacggtgtggaagaaggatggccagctggtagtggagggccggcgt cacctggtgtacgaggacgctcaggagaactttgtgctcaagatcctcttctgcaagcag tcggaccggggcctctacacctgcacggcatccaacctggtgggccaaacctacagctcc gtgctggtcgtcgtgcgagagcccgctgtacccttcaagaggcgacttcaggacctggag gtgcaggagaaggagtcggccacgttccagtgcgaggtgcagctgccgtccacggaggcc acgtggtacaaggaggagacgcggctgtgggccagcgccaagtatggcatcgaggaggcg ggcactgagcgccggctcacagtgcgcaacgtctcagccgacgacgacgctgtctacatc tgcgagaccacggagggcagccgcacagtggctgagctcgcggtgcaaggcaacctcatc cggaagctcccgaggaagaccgcggtacgagtgggtgacacggccatgttctgtgtggag ctggccaggcaggagggccccatccgctggctgaggaaccaggaggaggtggtggctggg ggccgcgtggccatcaccacagaaggcacgtgccacacgctgaccatctcccagtgcagc ctggaggacatgggcgaggtgaccttcactgctggtgactgccggacgtccacccagttc tttgtgtctgcccctaggaggccgcccctgcacgcccctgaggccccagtggtaaaggcc aggacagagttctccgtcaccctcgcctggtctccaccacctcacggggacctccctgtc cccatcgatggttatctggtggaaaagaagcggcttggtgcctatgcctggagccggtgc cacaaggcggagtgggtggctgagcacaagctgaccgtggccaacgtggctgaggagggg gacttccagttccgggtatcagctgtaaacagctttggccagagcccctacttggagttc ccagggactgtccacctggccccccagctggccgtgaagacacctctgaaggcagtggag gcagtggagggtggcgaggtgaccttctctgtggacctcactctggcctcggcgggcgag tggttcctggatggccagcccctgaaggccagcagcgtgtatgtgatctgccacgatggc acgcggcatgccctcaccatccgctctgtgtctgccagcctgaatggcgctgagctcaag ttcatggccaatggcattgagagcagcatccgcatggaggtccgagcggccccagggctg accaccaagcgtccagtagcagccgtgagggaagtgctggcccggttgcatgaggaggcg cagctcctggccgaactgtcagaccaggccgcggcggtgacatggctgaaggatggtcac gcactgcccccaggccccaagtacgaggtgcaggcaagcgccgggcagcgggcgctgctg gtgcgtgacgtggttcgagacgatgctggcctgtacgagtgtgtcagccgtgggggccgc atcgcctaccagctgttggtgcaagggctcactccctttctgcacaaggacacagctggt ggcttcgtggatgttgtggctgggggcccggtgcactttgaatgtgagacttctgaggcc caggttcgtgtgcactggtacaaagatggcacagagctcagcggctccagccagcgcttc ctgcaggaggacgtgggcacatggcaccggctggtggcagcctcagtcagcaggcaggat gagggcacctactcgtgccgcgtgggtgaggactccgtggacttccagctgcgtgtccat gagccctcagccatgtttgctaaggggcagccggcatgcagtgcggtgcaggccaaggcg gggaccagcgccacgctgagctgtgaggtggcccaggacaagacggaggtgacatggtac aaggatgggaagaagctgaatgccagctccaaagtgcatatggaggccaagggctgcagc aggaggctggtggtgcagcaggcggggaaggcggatgctggggagtacagctgcgaggcg gggggagagaaggtctccttccacctggatgtcacagaacctgtattggtgtttgccaag gggcagccagcacgcagtgaggtgcagaccaaggtgggggccagtgccacgctgagctgc gagatggcccaggacaagacagaggtgacatggtacaaggacgggaagaagctgagtgct agctccagagtgcacgtggaggccaagggctgcagcaggaggctggtggtgcagcaggca gggaaggcggatgtcggggagtacagctgcgaggcggggggccagaaggtgtccttccac ctggacgtcacagagccctcagccatgtttgctaaggggcagccagcatgcagtgaggtg caggccaagctgggggccagcgccactctgagctgcgacgtagcccaggacaagatggag gtgacatggtacaaggacgggaagaagctgagtgccagctccagagtgtgcatggaggcc aagggctgcagcaggaggctggtggtgcagcaggcagggaaggcggatgccggggagtac agctgtgaggccgggggccagaaggtgtccttccgcctggacgtcacagagcccacaacc atgtttgtcaaggagcagccagcacacagtgaggtgcaggccaagccaggggccagtgcc atgatgagctgtgaggtggcccaggacaagacagaggtgacatggtacaaggacgggaag aagctgagtgccagctccagagtgcacgtggaggccaagggctgcagcaggaggctggtg gtgcagcaggcggggaaggcggacgctggggagtacagctgcgaggcggggggccagaag gtgtctttccacctggatgtcacagagcctgcagccatgtttgccaaggggcagccagca cacagtgaggtgcaagccaaggcgggggccagtgccacactgaactgcgaggtggcccag gacaagacggaggtgacatggtacaaggacgggaagaagctgagtgcgagctccaaagtg cacgtggaggccaagggctgcagcaggaggctggtggtgcagcaggcagggaaggcggac gccggggagtacagctgcgaggcggggggccagaaggtgtccttccgcctggacgtcaca gagccctcagctgtgttttccaaggagcagccagcacacagtgaggtgcaggccaaagcg ggggccagtgccacactgaactgtgaggtggcccaggacaagatggaggtgacgtggtac aaggacgggaagaagctgagtgcgagctccaaagtgcacatggaggccaagggctgcagc aggcggctggtggtgcagcaggcggggaaggtggatgccggggagtacagctgcgaggcc aagggccagaaggtgtccttctgcctggatgtcacagagccctcagttgtattttccaag gagcagccagcacacagtgaggtgcaggtcaacgcgggggccagcgccacactgaactgt gaggtggcccaggacaagatggatgtgacatggtacaaggatgggaagaagctgagtgag agctccaaagtgcacatggaggccaagggctgcagcaggaggctggtggtgcaacaggca ggaaaggcagacgccggggagtacagctgcgaggctgggggccagaaggtgtccttctgc ctggacgtcacagagcctgtatccatgtttgctaaggagcagctagcacacagtgaggtg caggccaagatgggggccagtgccatgctgagctgtgaggtggcccaggacaagatggac gtgacatggtacaaggatgggaagaagctgagtgagagctccaaagtgcacatggaggcc aagggctgcagcaggaggctggtggtgcaacaggcagggaaggcagacgccggggagtac agctgcgaggctgggggccagaaggtgtccttctgcctggatgtcagagagccctcagct gtattttccaaggagcagccagcacacagtgaggtgcaggctaaggcgggggccagcgcc acactgaactgtgaggtggcccaggacaagatggatgtgacatggtacaaggatgggaag aagctgagtgagagctccagagtgcacatggaggccaaaggctgcagcaggaggctggtg gtgcaacaggcaggaaaggcagacgccggggagtacagctgcgaggctgggggccagaag gtgtccttctgcctggacgtcacagaacctacagtggtgtttgccaaggagcagccagca tgcagtgaggtgcaagccaaggcgggggccagtgccacactgagctgcgaggtggcccag gcccagacagaggttacatggtacaaggacgggaagaagctgagtaccagctccaaagtg cacgtggaggccaagggctgtagcaggaggctggtggtggagcaggcagggaaggcggac gccggggagtacagctgtatggccaatggccagaaggtgtccttctgcctggacgtcaca gagtactcagctgtgtttgccaaagagcagccagcatgcagtgaggtgcaggccaaggca ggggccagtgccacaatgagctgcgaggtggcccaggcccagacagaggttacatggtac aaggacaggaagaagctgagtgccagctccagagtgcacgtggaggccaagggctgcagc aggaggctggtggtgcagcaggtggggaaggcggacgccggggagtacagctgtgaggcc ggggaccagaaggtgtccttccacctggacgtcacagagcctggggcctgtttcaagacc tcagccatgtttgccaaggggcagccagcatgcagtgaggtgcagaccaaggtgggggcc agtgccacaatgagctgtgaagtggcccaggacaagacagaggtcacatggtacaaggat gggaagaagctgagtgcgagctccagagtgcacatggaggccaagggctgcagcaggagg ctggtggtgcagcaggcggggaaggcagatgccggggagtacagctgcgaggctgggggc cagaaggtgtccttccacctggatgtcacagagatctcggccgtgtttgccaaggagcag ccagcacacagtgaggtgcaggccaaggccggggccagcaccacgctgagctgcgaggtg gcccaggaaaagacggaggtgacatggtacaaggatgggaagaagctgagtgccagctcc agagtgcacgtggaggccaagggctgcagcagtaggctggtggtgcagcaggcggggaag gcggacaccggggagtacagctgcgaggcggggagccagaaggtgtccttccgcctggac gtcacagagctggagcctgaggcccccactgtggagagacccggccacaaggagcctctg gtggtcaaggagcacgaggacattgtcctgaccgccacgcttgcgacaccctctgtggcc gcggtgaggtggttcaaagacggcgtggagattcgccgcagtaagcggcatgagaccacc agcctggaggacacccacaccctgagaatccgcagggcccaaaccttggacacggcagtc tacagctgccgcgtgggcgcagacgggcaggatttcccggtgcaggtggaagaggtggcc gctaagttctgccgtcccctggagcccgtacgcggggagctgggccgcacggtaacactg atctgcgagctgagcccaccgcaggctgaggtggtgtggcactgtgggagcacgcagctc cgggcaagcaagcgcttccagatggaagccgctgggccccggcggtctctcaccgtgtcc gacctgcggctggaggatgcgggggagtatgcgtgtgagacccgtgatgatcgtaccagc gcgcagctcaccgtcagtgccccccgcacggtcaagttcacgcctgggttgagtgccatg gtggcagaggagggccaggaggccaccttccagtgcgtggtgtcccccagcgacgcagca gtcatgtggttccgggacggcgcctcactgcagcccagcgagaagttcctcatctctcag agtggcgccagccacagcctgactatcttaggcctgaccctggaggatgctggccagatc accgcagaggctgagggggtctcaacggctgctccactccgggtgcgagaggctccagtg ctgttcagaaagaaactggagccacagacagtggaggagcagagctcagtgaccatggag gtagagctgacacggccatggcctgaggtcaagtggacgcggaatgccacggccctggca ccaggcaagaatgtggagattcacgccgagagcaccaggcaccgcttggttcttcagtgc gtgggttttgaggaccgtggcttttacggctgtgagactccagacgacaagacacaggcc aagctcactgtggaaatgcgccaggtccggcttgtgcggggcctccaggcggcagaggct tgggagcagggcacggccaccatggaggtggagctgtcacatgaccacgtggagggcagc tggacacgagacggcgtgcggctgcagccagggcccacatgccagctggctgtgcagggc cccatccacaccctcactctgttggggctgcggccgcaggacagtggcctcatcgccttc aaagcggagggggtgcacacgtccgcgaggctcacggtcactgagctgcctgtgcggttc agccgccctctgcaggacgtggtggccacggagaaggacagagtgaacctggagtgtgag ctgtctcgccctaacgtggacgtgcgctggctgaaggacggcgtagagctgcgggtgggc aagacagtgggcatggtggcccagggcacgtgccggagtctcatcattttccactgtgag cttggtgaccagggcgtgtacgtgtgtgatgctcgtgatgctcagagctcagcctccctg aaggtgcaaggtcgcaatgttcagatcgtgacgcacctggaggatgtggaggtgatggaa aaggagggtgccaccttctcctgcaagatctctcatgacgaagtgccggcccagtggttc tgggagggcaataagcttcggcccagcgacaacgtgcgcatccgccaggaaggaaggaca tacaccctcatctaccggagggtcctggcagaagatgcaggggagatcaaatttgtagct gaaaacgcagaatcacgagcccagctccgagtcaaagagctgccggtaaccatcctgcgc ccacttcgggacaagatcgccatggagaagcaccgcggtgtgctggagtgccagatgtcc agggccagcgcccaggtgcagtggttcaagggccacgtgcagctgcagccggggcccaag tatgagatggtcagtgacggcctctaccgcaagctgatcatcaatgacgtgcagccagag gatgaggacatctacacatgcgatgccagcgatgtgaagaccagcgcccagttcttcgtg gaagagcaatccatcaccatcgtccgggtcctgcaggatgtgacggtgatggagcccgca cccgcctggttcgaatgcgagacctccatcccctcggtgcggccgcccaagtggctcctg ggaaagacggtgctccaggccgggcccaccatcggcatggagcaggagggcacggtgcac cggctgacgctgcggcgtacctgctccaccatgaccgggccggtgcacttcaccattggc aagtcgcgctccaccgcgcgcctggtggtctccgacatccccatggtgctcacatggccc ctggagcccaagtcgggccgcgagcagcagtccgtggtcctgtcctgcgacttcaagccg ccccccaaggccgtgcagtggtacaaggaggacacgcccctggcgccctcagacaagtac aagatgaggctggagggccacatggcggaactgcgcatcctcaggctcacacccgcagat gccggcgtctaccggtgccaggccggcagcgcccagagcagcgccgaggtcacagtggaa gcacgcgaggttacagtgatgaagccaatgcaggacgcagaagccacggaggaaggccgc gcctgcttctcttgcgagctgtcccatgaggacgaagaagtggagtggtcgctcaacggc acacctctgtacaacgacagcttccacgagatctcccacgagggccgtcgccacacgctg gtgctgaagcgggttcggcgggccgacgccggccttgtgcgcgcctgctcccccaaggtg tcggtcactgcccgcctggaggtcaaagcaaagccggtggtgttcctgaaggcgctggac gatgtgtccgcagaggagcgcggcacgctggccctgcagtgcgaggtctcagacccccag gcccacgtggtttggcgcaaggacggagtggagctgggccctagcgacaagtacgacttc ctgcacacagcgggcacgcgcggtctcgtggtgcatgacctgagccgggacgacactggc ctctacacttgcagcgtgggctcggaggagacccgcgccagagtcagcgtgcacgacctg cacgtgggcatcaccaagaggctgaaatcggcggaggtgccagaaggccagagctgcacc ttcgaatgtgtcctgtcccatgagaaccctggcgatgtggccacatggacagttggcggg aagacagtgggtagctctggccgcttccgggccacactccagggccgcaaatataccctg gttgttcaagatgcggctcctggagatgctggggaagtggtgttctccgtgcgggacctc acctccaaggcctccctcatcgttagagagaggccagcgggtatcacaaagcctctggaa gaccagcaggccactccaggtgaggacgcggtgctgagctgtgagctgtctcgggccggg acctcggtgcgctggctgaaagacgggaaggccattcgcaagagtcagaagtacgacctg gttacagaaggcactcgggccacgctggtggttcgtgccgtgtcgctcaaggattcgggc gaatacacatgtgagacagaagcttccaagagcacagcaagcctccgtgtggaagaaaag gccaaccggttcacagacgagctgaccgacctgcaggtggaagagaagggcacagctgtg tttctgtgcaagacggagcgtcccgcaaccacagtgacctggcgcaagggcctcacggag ctgcatgcctccgggaagcacacacccagccaggagggcctgaccctgcagctcaccatt agcaccttggagagggcggacagcgacatgtacacctgtgacatcggccaggcctgttcc caggcccggctcctggtgcaaggccggaaagtgctcatcacagaggatctggaggacgtg gaggtgcgagagggctcctcggccaccttttcctgccgcatctcccctgctgactatggg cccgtccactggttcttggacaagacgcccctgcacccgaatgagcttaatgagattgag gttcagccaggtggctaccatgtgctgactctgaggcagcttgcgctcaaggactcaggc actgtccactttgaggctggggaccagcggacctcagccactcttcaggtcacagaaaag ccaagtgtcttctcccgggagctcacggaagccacagtcacagaaggggaggatcttacc ttggtctgtgagaccaccatcctggacagccccgtgtgctggaccaaggacgggaaggcc ctgcggccatcagcccggtgccagctgagccaggagggccaccgggcccagctggtcatc aagggcaccaccgtgcaggacggcgggcgctacaagtgtgaagctgggggctcctggagc agctccatcgtcagggtccatgcacggcccgtgtggttccgcgaggggctgaaggacctg gaggtgccagagggccgagctgccacactgcgctgtgtgctgtcatctgtggccgcgcct gtggagtggcgccgtggagatgaggctctgcggcctggaggcaagtacagcctgcgtcaa gagggcgcagtgctggagctggtagtccgggacttgcggccccaggacactgggcagtac tcctgccactttggggaccagatgaccatggccatgctcacagtgaaggccttgtctgct gagttcatagggagactgagaagcaaggaggcctcagaaggggccacagccacgctgcgc tgtgagctgagcaaggaggcccccgtggagtggaagaaggggtcccaggccctcagagct ggggacagagtgagcctgaggcaggatgggaccgtgtgtgagctggagatccgtggcctg gctgtggcagacgctggggagtactcatgtgtgtgcgggcaggagaggacatcagccacg ctgactgtcagggctctgcctgctgagttcatagggagactgagaagcaaggaggcctca gaaggggacacggccatgctgcactgtgagctgagcaaggaggcccccgtggagtggagg aaggggtcccagaccctcagagctggggacagagtgagcctgaggcaggatgggaccatg tgtgagctggagatccatgacctggccctggcagatgccggggagtactcatgtgtgtgt gggcaggagaggacatcagccacacttaccgtcagagccctgcctgccaagttcacaaag aacctgaggaaggaagaggccatggaaggagccacggccatgctgcgctgtgaactgagc aaggcagttcctgtggagtggaggaagggttcccagatcctcagagctggggacagagtg agcctgaggcaggaggggaccatgtgtgagctggagatccgtggcctggctgtggcagat gctggggagtactcatgtgtgtgtgggcaggagaggacatcggccacactgaccgtcagg gccctgcctgccaagttcacaaagagcctgaggaaggaagaggccgtggaaggggacatg gccactctgcactgtgagctgagcaaggcggtccctgtggagtggaggaaggggtccgag accctcagagccgggaacagggtcaccctgagacaggaggggaccgtgtgtgagctggag atccgtggcctggccttggcggacaccggagaatactcatgtgtgtgcgggcaagagagg acatcagccgtgttgactgtcagggcactgcctgctcagttcatccaagatctgaagacc aaggaggccatggaaggggccatggccacaccgcactgtgagctgagcaaggcggtcccc gtggaatggaggaaggggtccaagaccctcagagctggggacagagtcagactgaagcag gacagaactgtgtgtgagctggagatccatggcctggtcgtgtcagatgccagagagtac tcgtgtgtgtgtgggcaggagaggacatcagccacgctgactgtcagggccatgcctgcc aagttcacaaagagcctgaagaaggaagaggccacagaagggaccacagccattctgcgc tgtgagctgagcaaggtggcccctgtggagtggagaaaggggtctgagaccctcagaacc agggacagaatgagcctcaggcaggatggaactgtgtgtgagctggagatccgtgacctg gccttggtggatgccggggagtactcgtgtgtgtgcgggcaggagaggacattggccatg ctgaccatcaggggcctgccccccaagtttacaaaaagcctgaagaaggaagaggccact gaaggggctacggccactctgcgctgtgagctcagcaaggcggtccccgtggagtggagg aaggggtctgagaccctgagagctggagacagagtcagcttgaagcaggatgggaccata tgtgagctggagatccatggcctgattatggaggatgccggagagtactcatgtgtttgc ggtcaggagaggacatcagccacactgactgtcagggccctacccgccaagttcacaaag aacctgttgaaggaagaggccactgaaggggctacagccactctgcactgtgagctgagc aaggtggtccccgtggagtggaggaaggggtccgagactctcagagccggggacagagtc agcctgaagcaggatgggaccgtgtgtgagctggagatccatggcctggccttggaggac actggagagtactcgtgtgtgtgcgggcaagagaagacatcggccatgctgaccgtcatg gcactacctgccaagttcacaaaaagtcttggaaaggaagaagccacagaaggggccaca gccaagctgtgctgcaagctgagcaaggtagcccctgtggagtggaggaaggggtccaag accctcagaactggggacagagtcagcctgaggcaggatggaaccatgtgtgagctggag atccatggcctggctgtggcagatgccggggagtactcatgtgtgtgcggacaggagagc acatcggccatgctgaccgtcagggccctgcctgccaagttcacaaagagcctgaggaag gaagaagccacggaaggggacacggccactctgcactgtgagttgagcaaggcgatcccc gtggagtggaggaagggatctgagaccctcagagccggggatagagtgagcctgaagcag gaggggaccgtgtgtgagctggagatccatggcctggccttggaggacactggagagtac tcgtgtgtgtgcgggcaggagagaacatcagccatgctgactgtcagggccctgcccgcc aagttcacaatgagcctgaggacagaagaggccacagaaggggccacagccattctgcgc tgtgagctgagcaaggcagtccctgtggagtggaggaagggtactgagactctcagagct ggggaaagagtgagcctgaagcaggatgggactgtgtgtgaactggaaattggttgtctg gccatggcagatgccagagagtacgtgtgtgtgtgtgggcaggagagaacatcagccacg ctgtcaggggtaaacaccatgtgtgccttgcccaccaagttcacaaagaacctgttgaag gaagaggccatagaaggggccatggccactctgcgctgtgagctgagcaaggcggtcccc gtggagtggaggaagggatccgagaccctcagagctgggaacagaatcagcctgaggcag gatgggaccgtgtgtgagctgcaaatccgtggcctggctttggcggatgccggagagtac tcatgtgtgtgcgggcaggagagaacatcagccacgctgtctgtcagggccctgcccgcc aagttcacaaggagcctgaggacagaagaggccacagaaggggccacagccattctgcta tgtgagctaagcaaggtggcccctgtagagtggaggaaggggtccgagacccttagagct ggggacagagtgagcctaaagcaggatgggacaatgtgtgaactggagatccgtggcctg gccgtggcagatgccggagagtactcgtgtgtgtgcgggcaggagagaacatcagctatg ctgactgtcagggccccgcaggtggtgttcaaggagccgctgcagagcatgcaggctgag gagggtgcctcagccaccctgcggtgtgagctgtcccagcccaatgctgctgtggtctgg agcaagggcggtctggagctgcaggctgatgggcgccgggagcctcggcagcggggccac actgcagagcttatgcttcgggacctgcgcagagaggacgcgggcgagtacacctgtgcc tgtggacctcaggccaccagtgctgccctcaccgttacagctgcaccagtgcacttcctc cgggagctgcaggcccaggaggtggatgaaggtgcaacagcccacttgcgctgtgagctg agccgagagggcgctagcgtggagtggcgcaaggactccctgcagctcttcccttgtgcc aagtaccagatggtgcaggagggaagggctgctgagctgcgggtgcatggcaccgagcag gaggacgccggccattacacctgtgacacaggccacgcacagagcacggccagcctctcc gtccgagcccctaggcccatattccagatggagctgcagagcacagggcaggaggccggc agtgtggcccggctacactgccagctgagtgaggcagagcccggcgtcccggtgcagtgg cttaaggagggtgtggagctgcatatgagccccaagtacgagatacggcgtgtggggacc acgtgtgagctgctgatccacgggctggagaccaaggacaccggcgagtacgtctgcgtg gccggtggtcagaaaaccgtggcctctgtcatggtcaaagagcccgaggtgaccattgtg cgggggctggaggatgctgaggtgcaggttgatggggacgtggagttccgttgccagctg tcacgggccggggccacagaggtggagtggcgcctccagggcctaccactgcagaacaat gaggtgacggagctggccgtgcagggtggctgcacccacactctgaggctgaagggtgtg acccctgaggacgcaggcatcgtctccttccacgtgggcgcccacacatcctctgcccag ctcactgtccgagtccccgaggtgagcatcctggagcccctgcaggacgtgcagctcagt gaaggccaggacgcccacttccggtgccagctgtctagggcctgcggccaggaggcctgc tgggccctgggaggggtgcccctgcaggccaacgagatgaacgacatcactgtggaacac ggcacgctgcacctgctcactctgcataaggtgaccctggaggatgctggaaccattagt ttccaagtgggctcgtgtagctctgaggcccagctgaaggtcacagccaagaacaccgtg gtgcgtggcctggagaacgtggacgcacttgaaggcggcgaggcgctgttcgagtgccag ctgtcccgccccgaggtggccactcacacctggctgctggacgacgagcctgtgcgaacc tccgagaacgcggaggtggtctacttcgagaatggcctgcggcacctgctgctgctcaaa aacctgcgtccgcaggacagctgccgggtgaccttcctggcgggggacgtggtgacctcc gcgttccttacagtcagaggctggcgcctggaagtactggagtccccgcaggatgcggcc gtgagagctggtgggcaggtccgcttcaggtgcacgctcagcgaggcggtgccggtgggc gagacgacgtggtacatcaacggggccgcagtgcagccggacgaccccgactggatggtc accgcagacggcagccaccacaccctgctgctgcgcggtgcgcagccacaccacgctggc gaggtcaccttcgccgcccgcgacgccgtggcctccgcgcggctcaccgtgctaggcctc ccagaccctccagaggacgcagaggtggtggcgcgcagcggccgctccgtgacactgtca tgggtggcgcctgcaagcgacggtggcggcggtctctgcggctatcgggtggagatgaag gcggtggccaccggcgagtggcggctgtgccacgagttggtgcctgggcccgagtgcgtg gtggacggcctggccccgggagagacctaccgcttccgcgtggcggcagtaggcccagcg ggggctggggagcctgtgcacctgccccagatggtgaagctcggtgagcccccgcccccg tgcctgcggcccctgcctcctgcgcctcccgctctcgagagccggcaggtggctgccggc gaggacgtgttcctggagtgcgaggtggccgaggcaggtgaggtcgtctggctgaagggg acagaggtcatccaacccagcgggcgcttccaggtcctctgccagggtcagcggcagacg ctggtgatccagagcttctcagcgttggaccagggggagtaccattgcggccacgccggg gaacaggcctcctctgcagccgcctctttccgggtggtgctgtccccaggatctggggac gaggcccctgcacagcccaggctgccccccgaagcagcccaggagggtgacctgcacctg ctgtgggaggccctggcccggaagcgccgcatgagccgtgagcccacgctggactccatc agtgagctgcctgaggagaatggccgttcaccacgcctgcagcaggaggtggaagaagcg gccccagacctctctgaggactactccacagccgatgagctggcacgcactggcgaggcc gacctctcacacaccagctctgatgatgagtcccgggcaggcactccctccctggttacc tacctcaagaaggctgggaggaccagcacctctccactggccagcaagcttgggatccct gcagttgggaagccactgaagcatcaggaacagccaactgcaggtcacccacctccggga gatctgagggctgcggacttgggtgacccgtccatggacaaggcagcagtgaagatccag gctgcctttaaaggctacaaagtccgcaaagagatgaaacagcaggagggacccgtgttc tcccgcacatttggggataccgaggcacaggtgggggatgtcctgcgtctggagtgtgtg gtgtccagcaaggcggacgtacgtgctcgctggctgaaggacggcatggagctgactgac agccggcaccaccacatcgaccagcttggggacggcacctgctgtctcctggtcacgggc ctgggtcgtggggacgccggccgctacacctgccaggtgagcagcaagttcggccgcgtg gcccacagtgcctgtgtggtggtcagcgggacggagagtgaggcggagagctcctcaggg ggcgagctggacgacgccttccgccgggcagcccgacggctgcaccgtctgttccgcacc aaaggcccggcggaggtgtcggacgaagagatcttcctaagtgcagacgagggcccggcg gaaccggaggagccggcagactggcggacataccgcgaagaagaacactttgtctacatt cgcttcgaggctcttgccgaggcccaccgtgcggccacctgcttccgagaaatgtttggc acgatgggtattggcgtggacatcagcctgttggagcaggggccccggggggtggagatg cgcatcagcaaggtggctcctgccccagtcacagctcaagaggtggtgccccggccgctg acctcagaggctgccccggtgttcctgactgagctgcagaatcaggaggtgcaggacggg taccccgtgagcttcgactgtgtggtgacaggccagcccgtgcccaccgtgtgctggttc aaggatggcaggatgctagaggaggatgaccactacatgatcagtgaggaccagcaaggc ggccaccaacttatcatcacggcagtggtgccagcagacatgggtgtctaccgctgcatg gctgagaacagcatgggtgtgtcatccaccaaggcggagctccgtgtggacctgactagc acagactatgaaactgcagctgatgccacagagacctcctcttacttcagcgcccaaggc tacctgtccagccgggagcaagaggggacggaatctacctcagaggaggggcagctgccc caggtggtagaggagctgaaggacctccaggtggcccctggcacgcgcctggccaagttt cagctcaaggtgaaaggctacccagcgccccggctgtactggttcaaagacgggcagccc ctgacggcttctgcacacatctgcatgactgacaggaagacgcttcacaccctggaggtt gtatcggtcaccagggaggatgccggccagtactcagcctacatcagcaacaccgtaggc gctgcctactcatcagcccggctgctggtccgaggccccaaagatcctgaagagaagccg gcatcggatgtgcaccagcagctggtgccgcctcgattcctggaaagattcacctccaag aaagtgaagaaaggctccagcatcaccttctcagtgaaggtggaaggatgtccggcccca gccgtgcactggctgcgggaggaggctgagcgaggagtgctgtggattggccgtgacaca ccaggctacacggtggccagttctgcacagcagcacagtctggtcctgctggatgtgagc agacagcaccgaggcacatatacctgcatcgccagcaatgctgcgggccaggccctctgc tccgccagcctgcacatctctggcttgtccaaggaggcaggggcagcagaggagcatgtt ggggtgaaggaggccctcatctccaccttcctgcaggggacccaagccgtctccacgcag atgtcagaacccacaggtttcactgaccttgccgggcagaggaaagagcccccagtggtg gaggcccgtggccacttgtccctggctgaagtgggcacagaagagttcctgcagaagctc acctctcagatcacggagatagtgtcggccaagatcacgcaagccaagctgcaggtgcct ggaggtgacagtgacgaggaatctaagacgccgtctgcatccccctggcatggccgttcc cgcccctcctccagcgtgcaggagtcatcctcggaatcggaggatggggactcccgcggc gagatcttcgacatctacgtggtcacagctgactacctgcccctgggggctgagcaggac gccatctcactgcgggagggccagtatgtggaggtgctggactcggcccacccactgcgc tggctcgtgcgcaccaaacccaccaagtccagcccctcacggcagggctgggtatcccct gcctacctggacaggcggctcaagctatcacctgagtgggggcccactgaggcccccgag ttcccaggggaggctgtgtctgaggatgaatacaagacaaggctgagctccatcatccag gagctgctgaactccgagcaggcctttgtgagcaagctgcagttcctacagagccaccac atgcagcacctggactgctgcccccacgtgcctgccgccgtggcctcccagaaggctgtc atcttccgaaacgtgcaggacatcagccacttccacagcagcttccagaaggagctgcag cagtgtgacacagatgacgatgtggccatgtgcttcatcaagaaccaggcggcctttgag aagtacctggagttcctggtgggccgcgtgcaggccgagtcagcagtggtcagcacggct gtgcaggagttctacaagaaatacacggaggaggtgctgtcagccgcagacccctctcag ccgccgccgccgcccctgcagcacttcctggagcagccagtggagcgtgtccagcagtac caggccctgctaaaggagctgatccgcaacaaggcgagaaaccggcagaactgcgcgctg ttggagcaggcgtacgccgtggtgtcggccctgccgcagcgcgctgagaaccagctgcac gtgtcgctcatggagaactacccgggcaccctgcaggccctgggcgagcccatccgccag ggccacttcatcgtgtgggagggggcgccaggtgcgcggatgccctggaaaggccaccac cggcatgtcttcctgttccgccaccacctggtggtctgcaagcccagacgggactcccgc accgacaccttcagctacgtcttccggaacatgatgaagctgagcagcatcgacctgaac gaccaggtggagggtgacgaccgtgccttcgaggtttggcacgagcgagaggactctgtg cgcaagtacctgctgcaggcacggaccgtcatcaccaagaattcctgggtgaaggagatc tgtggcatccagcagcgcctggtcctgcctgtgtggcaacccccagatttcgaagaggaa ctggcggactgcacagctgagctgggcgagactgtcaagctggcctgccgtgtgacaggc acacccaagcccatcgtcagctggtacaaagatgggaagccagtggaggtggaccctcac cacatcctcatcgaggaccccgatggctcgtgtgccctcattctggacaacctgactgga gtggactccggccagtacatgtgcttcgcagccagtgctgcaggcaatgccagcaccctg ggcaagatcctggtgcaagttcccccacggtttgtgaaaaaggttcgggcggtgcccttt gtggagggagaggatgctcaggtcacctgcaccatcgaaggcgccccacacccccagatc aggtggtacaaggatggggccttgctgacacccagcagcaagtaccgaaccctgagtgag ccccgcagcggcctgctggtgctggagatcttggcagccagcaaggatgacctgggccac tatgagtgtgagctggtgaacaggctgggctctgcaaggggcggggcagagctgtgcatg cagagccctgccatgagggcccgggaacaacgtcgcagggagcagcttgcagctgtggaa gatgttgttgcccctcccccagttgccctggagacaacagaccaggagattacatctgtt ccaaggacgctggtgtgccccaaagctccaggaccctccacaggggaccatgctggctcc agccctggctctaggggagcacccaaactccaggaggctggcccccaactcccaggcaca gaggctgcagatgcatctggtgtgctccagaaggtgccagagcctctcccccaggagggc caggagcaggaggtgggggcccacgctgaggcccagggactcactgtgcctatccggatg gagggcacagcctggccgggggcaggcgtggtggagctctgggacatccatagccaggtg ttcacggagaccaagcatcggacatacgtgtaccaggccagcgacacgggtgccacaagg cccccgtccatgcaggtcactattgaggatgtacaggcacagaggggcagcatggcgcag ttccaagcggtcatcgagggcaacccgcagcccacagtgacctggtaccgggatgatgcc cagctggtggatggtgcccggctcagccagcagcaggaagggaccacatactccttggtg ctgagggatgtgacccagcaggacgctggcgtctacacttgtctggcccaaaatgctggt ggccaggtgctgtgtaaagcggagctggtggtccatgggggagacagccagcctgactct gagaagcaaagctatcgaaggaagctgcactccttctacgaggtcaaggaggaaattgga aggggcgtgtttggctttgtgaagagggtgcagcacaagggaaaccagatgttctgtgca gccaagttcattcccctgcggagcaggacgcgtactcaggcttaccgcgagagagacatc ctggccacgctcagccacccactggtcacagggctgctggaccagtttgagacccggaag accctgatcctcatcctggagctgtgctcctcagaggagctgctggaccggctgttcaag aagagtgtcgtgacagaggctgaggtcaaggtgtacatccagcagctggtggaggggctg cagtatctgcacagccagagtattctccacttggacataaagcccccaaacatcctgatg gtgcatcacgctcgggaggacattaaaatctgcgactttggctttgcccaaaaaatcacc ccagaggagccacagtacagcaagtatggctccccggagtttgtgtcccctgagatcatt gagcagacccctgtgagcgaggcctccgacatctgggccatgggggtcatctcctacctc agcctgacctgctcgtcaccatttgctggtgagagtgaccgagccaccctcctgaatgtg ctggaggggcgggtgtcttggagcagccccatggctgcccacctcagcgaggatgcccag gactttatcaaggctgccctgcagagggccccagaggcccgacccagtgcagccaagtgc ctggcccacccctggttccagaagtccatacccgcagaggaggcccacttcatcaacacg aagcaactcaaattcctgctggcccgcagccgctggcagcgctccctgatgagctacaag tccatcctggtgatgcgctccatccctgagctgctccagggcccacccgacagcccatcc ctcggggtggccaggcacctgcgcggcgacgccagcgcctcctccagcagctcgtcctcg tcctcagacaacgagctggcacctttcgcccgggccaaatcgctgccgccctctccggtg acccactccccactgctgcacccgcggggcttcttgcggccgtccgccagcctgcccgag gaggccgaggcttgcgcgcccgccgccgccgcgcctccgcccgcgtcgtccccaggcgca gaggggccggccgccccgggctgcgtgccccggcagagcgtcatccgcagcctcttctac cagcaggcgggcgaggccccggagcgcggaggccccgccgcgggcggcaggcggcacccc gcgcggcggaggcacctgctcaagggcggctacttcgccagggccctgcccggcctgcgg gagccgctgctggagcatcgcacgctggaggaggaagccgcccgggaggagcaggccgct ctgctggccaaaacgccctccttcgagacagccctgaagctgcccggctccagcgcccgc ggggctccctgccgcagccgctccctggagctcgaccggccacactcccccagctcctcc gctgaggcctgtgagggggggcagtgccctggcccggccctctcgggcctgcagacaggg gagagcccgccgggaggtggcacatgtgccagggagattgagcgtccagagggatcctgg caggagccaagactattgccgtccatcggggaccacccgggggccgctcagcaagagaga tcatcccaggacagctgtgcggggcagcccgccccttccttccatccccagtggggtcct gctcccttgcaaggctgtggcccccctaaggctgttacaccgcaactttctggctccttc ccttcagagcagtgctcagggccccaacgggcatccttgagcaccttccccttgggggac acccagtcccccgtctttccagcccaagaaagcccccagccaggctctatggagggacca aaggagacccgtctccccaggaggctgagtccccctagctccccagggctggcctccctg gtgggcatggagcctggcccctcccaggatactgaggtcaaggccctggagccggaggat gcatcagagccggagcccagcccacagtggcctcaggagcaggccaccacacggaagttc tccctggggtggcgtgggggctatgcaggagtggctggctacggcacctttgcctttggt ggggacgcagggggcatgctgggccagggtcccctgtgggccaggatggcctgggccacc tctcagtcctcagaggagcatgacgatgctggggccaagagcccgccaccccaggccact gcagcgccccttcctgagggcagcggggcacccccaagggcctccccagagctgagctca tgggaagactttggcgggggctcccaggtgtccctggtgcagatccgagacctgtctggg gactcagaagcagcagacaccgtgtccctggacatctcagaggtggagcctgcctacctc aacttgtccgacctctatgacatcaagtacctccctttcgagttcatgatcttcaggaag gtccccaagcctgtggaagcagagtcaccatcctccccggaatctgacgctgaggaggag ctggctgagttcccagagaccacgtggccctggccaggtgctctgggtccgccggccagc ttacagatcacagaggaaccagaggacatggaggccctgctcacggaggctaccagcagt aggaagcggaagtggtcacccccctccggtggcctcttccacctccccgggaggcatgca ctggaggagcccctggagctggggctgcgccggagggtcagggcctcagtggcccacatc tcccgcctcctgaagggcaggcccgaaggtccggagaaggagagcccccccaggaagaag gcaggcctggcctcctttaggctggctctgaaaagcagggaccgagcaccatcctttcta agggagctctcagatgaaaccgtggttctgggccagtcggtgactcttgcctgccaagtg tcagcccagccagctgcacaagccacctggagtaaagatggggctcccctggaaagtagt ggccgcctcctcatctcctccacgctcaagaacttccagctcctgaccatcctggtggtg actgctgatgacctgggggtgtacacgtgcagcatgcgcaacacattggggaccgcagcc accacagctgtcctccggaaggcagagcgccctttgtcttctccacgccccgacattggg gaggtgtatgcagatggggtgctgctggtctggaagcctgtggagtcctacggccccgtg acctacatcgtgcagtgcagcctggaaggtggcagctggaacacgctggcctctgacatc ttcgactgctgctacggagccagcaagctttcgaggggcggcacctacaccttccggaca gcctgcgtcagcaaggcgggcatgggtccttacagcagcccctctgagccggtcctcctg ggagggcccagccacctggcctctgaggaggagagcagagccccacggccaggccagccc ctccccagcacggagaccttcgccttccagatgcagatccgaaggggccgcttcagcgtg gtgcggcagtgccgggagaaagccagcggacgcgcgttggccgcgaagatcgtcccctat cgccccgaggacaggactgctgtactgcgcgaatacgaggctctcaagagcctgcgccac cctcacctggcccagctgcaggccgcctacctcagcccccggcacctggtcctcatcttg gagctttgctcgggtcccgagctgctcccctgcctggcggagagggtctcctactcggaa tccgaggtgaaggattacctatggcagatgcttagcgccgcccagtacctgcacgcccag cgcattctgcatctggacctcaggtccgagaacatgatcgtcaccgagtacaacttactc aaagtcgtcgacctgggcaacgcccagagtctcgcccaggagaagatcctgccctctgag aggttcaaggactacgtggagaccatggctcctgagctcctggagggccagggtgccgtc ccgcagaccgacatctgggccataggcgtcacagccttcatcatgctgagcgcagagtac ccggtgaacagtgaagggacacgcgacctgcagaaagccctgcgcaaggggctcatccgt ctgagtcgctgctacgcggggctgtccggaggtgccgtggcttttctccggagcacgttg tgtgcgcacgcgtggggccggccatgtgcatccagttgcttgcagtgtccgtggctaacc gaggagggccctgcgggctcccatccggcagctgtctccttccccaccacgcgacttcga gccttcgtgcgcgagcgagagaagaagagggcgctgctgtacaagaagcacaacctggcc caggtgcgctga

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