Hyaena hyaena (striped hyena): 120226898
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Entry
120226898 CDS
T07257
Symbol
TH
Name
(RefSeq) tyrosine 3-monooxygenase
KO
K00501
tyrosine 3-monooxygenase [EC:
1.14.16.2
]
Organism
hhv
Hyaena hyaena (striped hyena)
Pathway
hhv00350
Tyrosine metabolism
hhv00790
Folate biosynthesis
hhv01100
Metabolic pathways
hhv04728
Dopaminergic synapse
hhv04917
Prolactin signaling pathway
hhv05012
Parkinson disease
hhv05030
Cocaine addiction
hhv05031
Amphetamine addiction
hhv05034
Alcoholism
Module
hhv_M00042
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:
hhv00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
120226898 (TH)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
120226898 (TH)
09150 Organismal Systems
09152 Endocrine system
04917 Prolactin signaling pathway
120226898 (TH)
09156 Nervous system
04728 Dopaminergic synapse
120226898 (TH)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
120226898 (TH)
09165 Substance dependence
05030 Cocaine addiction
120226898 (TH)
05031 Amphetamine addiction
120226898 (TH)
05034 Alcoholism
120226898 (TH)
Enzymes [BR:
hhv01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16.2 tyrosine 3-monooxygenase
120226898 (TH)
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Motif
Pfam:
Biopterin_H
TH_ACT
LTP_2
Motif
Other DBs
NCBI-GeneID:
120226898
NCBI-ProteinID:
XP_039081003
LinkDB
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Position
Unknown
AA seq
427 aa
AA seq
DB search
MVSQLDPPSSWTAEWPRAGRDPGALVAGRWRAAGTYEAQIHHLETRPAQRPRAGGPHLEY
FVRCEVPSADLPALLSSVRRVAEDVRGAGENKVLWFPRKVSELDKCHHLVTKFDPDLDLD
HPGFSDQAYRQRRKLIAEIAFQYKHGDPIPRVEYTAEEIATWKEVYTTLKGLYATHACRE
HLEAFQLLERFSGYREDRIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQC
TQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLY
WFTVEFGLCKQNGEVKAYGAGLLSSYGELLHSLSEEPEIRAFDPDAAAVQPYQDQTYQSV
YFVSESFSDAKDKLRNYASRIQRPFSVKFDPYTLAIDVLDSPRAIRRSLQDVQDELHSLA
QALSAIG
NT seq
1284 nt
NT seq
+upstream
nt +downstream
nt
atggtatcacagctggacccccccagctcctggacggccgagtggccgagggccggtcga
gacccaggtgcccttgttgctgggcgatggagggcggcagggacgtacgaagcccaaatc
catcacctggagacccggcccgcccagaggccgcgggcagggggcccgcacctggagtac
tttgtgcgctgtgaggtgcccagcgccgacctgcccgccctgctcagctccgtgcgccgc
gtggctgaggacgtgcgtggcgccggggagaacaaggtcctctggttcccaaggaaagtt
tccgagctggacaagtgccaccacctggtcaccaagtttgaccctgacctggacttggat
cacccgggtttctcggaccaggcgtaccggcagcgcaggaagctgatcgccgagatagcc
ttccagtacaagcacggcgaccccattccccgcgtggagtacacggccgaggagatcgcc
acctggaaggaggtctacaccaccctcaagggcctctacgcgacccacgcgtgccgcgag
cacctggaggctttccagctgctggagcgcttcagcgggtaccgggaggaccgcatccca
cagctggaggacgtgtcccgcttcctgaaggagcggacgggcttccagctgcggcccgtg
gccggcctgctgtccgcccgcgacttcctggccagcctggctttccgggtgttccagtgc
acccagtacatccggcacgcctcgtcgcccatgcactcccccgagccggactgctgccat
gagctgctggggcacgtgcccatgctggccgaccgcaccttcgctcagttctcccaggat
atcgggctcgcgtccttgggggcttccgacgaggagattgagaagctgtccacgctgtac
tggttcacggtggagttcgggctgtgcaagcagaacggggaggtgaaggcctacggcgcc
ggactgctctcctcctacggggagctcctgcactctctgtctgaggagcccgagatccgg
gccttcgacccggatgccgcggccgtgcagccctatcaggaccagacctaccagtctgtc
tacttcgtgtccgagagtttcagtgacgccaaggacaagctcaggaactacgcctcccgc
atccagcgccccttctctgtgaagtttgacccgtacaccctggccatcgacgtgctggac
agtccccgcgccatccggcgctccttgcaggatgtgcaggatgagctgcacagcctcgcc
caagcgctgagcgccatcggctag
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