KEGG   Hyaena hyaena (striped hyena): 120226898
Entry
120226898         CDS       T07257                                 
Symbol
TH
Name
(RefSeq) tyrosine 3-monooxygenase
  KO
K00501  tyrosine 3-monooxygenase [EC:1.14.16.2]
Organism
hhv  Hyaena hyaena (striped hyena)
Pathway
hhv00350  Tyrosine metabolism
hhv00790  Folate biosynthesis
hhv01100  Metabolic pathways
hhv04728  Dopaminergic synapse
hhv04917  Prolactin signaling pathway
hhv05012  Parkinson disease
hhv05030  Cocaine addiction
hhv05031  Amphetamine addiction
hhv05034  Alcoholism
Module
hhv_M00042  Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:hhv00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00350 Tyrosine metabolism
    120226898 (TH)
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    120226898 (TH)
 09150 Organismal Systems
  09152 Endocrine system
   04917 Prolactin signaling pathway
    120226898 (TH)
  09156 Nervous system
   04728 Dopaminergic synapse
    120226898 (TH)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05012 Parkinson disease
    120226898 (TH)
  09165 Substance dependence
   05030 Cocaine addiction
    120226898 (TH)
   05031 Amphetamine addiction
    120226898 (TH)
   05034 Alcoholism
    120226898 (TH)
Enzymes [BR:hhv01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.16  With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.16.2  tyrosine 3-monooxygenase
     120226898 (TH)
SSDB
Motif
Pfam: Biopterin_H TH_ACT LTP_2
Other DBs
NCBI-GeneID: 120226898
NCBI-ProteinID: XP_039081003
LinkDB
Position
Unknown
AA seq 427 aa
MVSQLDPPSSWTAEWPRAGRDPGALVAGRWRAAGTYEAQIHHLETRPAQRPRAGGPHLEY
FVRCEVPSADLPALLSSVRRVAEDVRGAGENKVLWFPRKVSELDKCHHLVTKFDPDLDLD
HPGFSDQAYRQRRKLIAEIAFQYKHGDPIPRVEYTAEEIATWKEVYTTLKGLYATHACRE
HLEAFQLLERFSGYREDRIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQC
TQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLY
WFTVEFGLCKQNGEVKAYGAGLLSSYGELLHSLSEEPEIRAFDPDAAAVQPYQDQTYQSV
YFVSESFSDAKDKLRNYASRIQRPFSVKFDPYTLAIDVLDSPRAIRRSLQDVQDELHSLA
QALSAIG
NT seq 1284 nt   +upstreamnt  +downstreamnt
atggtatcacagctggacccccccagctcctggacggccgagtggccgagggccggtcga
gacccaggtgcccttgttgctgggcgatggagggcggcagggacgtacgaagcccaaatc
catcacctggagacccggcccgcccagaggccgcgggcagggggcccgcacctggagtac
tttgtgcgctgtgaggtgcccagcgccgacctgcccgccctgctcagctccgtgcgccgc
gtggctgaggacgtgcgtggcgccggggagaacaaggtcctctggttcccaaggaaagtt
tccgagctggacaagtgccaccacctggtcaccaagtttgaccctgacctggacttggat
cacccgggtttctcggaccaggcgtaccggcagcgcaggaagctgatcgccgagatagcc
ttccagtacaagcacggcgaccccattccccgcgtggagtacacggccgaggagatcgcc
acctggaaggaggtctacaccaccctcaagggcctctacgcgacccacgcgtgccgcgag
cacctggaggctttccagctgctggagcgcttcagcgggtaccgggaggaccgcatccca
cagctggaggacgtgtcccgcttcctgaaggagcggacgggcttccagctgcggcccgtg
gccggcctgctgtccgcccgcgacttcctggccagcctggctttccgggtgttccagtgc
acccagtacatccggcacgcctcgtcgcccatgcactcccccgagccggactgctgccat
gagctgctggggcacgtgcccatgctggccgaccgcaccttcgctcagttctcccaggat
atcgggctcgcgtccttgggggcttccgacgaggagattgagaagctgtccacgctgtac
tggttcacggtggagttcgggctgtgcaagcagaacggggaggtgaaggcctacggcgcc
ggactgctctcctcctacggggagctcctgcactctctgtctgaggagcccgagatccgg
gccttcgacccggatgccgcggccgtgcagccctatcaggaccagacctaccagtctgtc
tacttcgtgtccgagagtttcagtgacgccaaggacaagctcaggaactacgcctcccgc
atccagcgccccttctctgtgaagtttgacccgtacaccctggccatcgacgtgctggac
agtccccgcgccatccggcgctccttgcaggatgtgcaggatgagctgcacagcctcgcc
caagcgctgagcgccatcggctag

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