Hyaena hyaena (striped hyena): 120237853
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Entry
120237853 CDS
T07257
Symbol
PDHA2
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
hhv
Hyaena hyaena (striped hyena)
Pathway
hhv00010
Glycolysis / Gluconeogenesis
hhv00020
Citrate cycle (TCA cycle)
hhv00620
Pyruvate metabolism
hhv00785
Lipoic acid metabolism
hhv01100
Metabolic pathways
hhv01200
Carbon metabolism
hhv01210
2-Oxocarboxylic acid metabolism
hhv04066
HIF-1 signaling pathway
hhv04922
Glucagon signaling pathway
hhv05230
Central carbon metabolism in cancer
hhv05415
Diabetic cardiomyopathy
Module
hhv_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
hhv00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
120237853 (PDHA2)
00020 Citrate cycle (TCA cycle)
120237853 (PDHA2)
00620 Pyruvate metabolism
120237853 (PDHA2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
120237853 (PDHA2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
120237853 (PDHA2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
120237853 (PDHA2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
120237853 (PDHA2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
120237853 (PDHA2)
Enzymes [BR:
hhv01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
120237853 (PDHA2)
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Motif
Pfam:
E1_dh
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
120237853
NCBI-ProteinID:
XP_039097232
LinkDB
All DBs
Position
Unknown
AA seq
391 aa
AA seq
DB search
MRKMLAAAVSRVLSGVTQKPASRVLVASCNYSKDATFPIKKCDLYRLEEGPPVTTVLTRE
DGLKYYRMMQTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPTDHVITSYR
AHGLCYTRGLSVRSILSELTGRRGGCAKGKGGSMHMYVKNFYGGNGIVGAQGPLGAGVAL
ACKYKGNKEVCLTLYGDGAANQGQIAEAHNMAALWKLPCVFICENNLYGMGTSVERAAAS
TDYYKRGHFLPGLKVDGMDVLGVREATKFAADYCRSGKGPIVMELQTYRYHGHSMSDPGI
SYRSREEVQNVRRKSDPIMLLKDRMVNSKLATIEELKEIDVEVRKEIEDAAQFATTDTEP
PLEELGHHIYCDTPPFEVRGANQWIKFKSLS
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgctgctgctgtctcccgcgtgttgtccggggtcacacagaagccg
gctagcagagtgctggtggcatcctgtaactattcaaaggatgctacgtttccaattaag
aaatgtgatctttatcgcttagaagagggccctcctgtcacaacagtgctcacccgggag
gatgggctcaaatactacaggatgatgcagactgttcgccgaatggaattgaaggcagat
cagctgtataaacaaaaatttatccgtggtttctgtcacttgtgcgacggtcaggaagct
tgttgtgtgggcctggaggccgggataaatcccacagatcatgtcatcacatcctatcgg
gctcatggcttgtgctatactcgtgggctctctgtgcgatccattctttcagagctgaca
ggacgaaggggaggctgtgctaaaggaaaaggaggttccatgcatatgtatgtcaagaac
ttctacgggggcaatggcattgttggcgctcaggggcccctgggagctggtgttgctttg
gcctgtaaatacaagggaaacaaggaggtctgtttgactctttatggggatggtgccgcg
aatcagggtcagatagctgaagctcacaatatggcagctctgtggaaattaccttgtgtt
ttcatctgtgaaaataacctctatggaatgggaacctctgttgagagagcagcagccagc
accgattactataagagaggacattttctccctggactaaaggtagatggaatggatgtg
ctaggtgttcgggaggcaactaagtttgcagctgactactgcagatctggaaaggggccc
atagtgatggagctgcagacctaccgctatcatggacacagtatgagtgaccctgggatc
agctatcgtagccgagaggaagttcagaatgtgagaaggaagagcgatcctattatgctt
ctcaaagacaggatggttaacagtaagcttgccactattgaagaattgaaggaaattgat
gttgaagtgaggaaagaaattgaggatgcagcccaatttgctacgactgatactgaacca
cctttggaagaattaggtcatcacatctactgcgatactccaccttttgaagttcgaggt
gcaaatcagtggatcaagtttaagtccctcagttaa
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