Hathewaya histolytica: NCTC503_00909
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Entry
NCTC503_00909 CDS
T05971
Symbol
cobB
Name
(GenBank) cobyrinic acid a,c-diamide synthase
KO
K02224
cobyrinic acid a,c-diamide synthase [EC:
6.3.5.9
6.3.5.11
]
Organism
hhw
Hathewaya histolytica
Pathway
hhw00860
Porphyrin metabolism
hhw01100
Metabolic pathways
hhw01240
Biosynthesis of cofactors
Module
hhw_M00924
Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide
Brite
KEGG Orthology (KO) [BR:
hhw00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
NCTC503_00909 (cobB)
Enzymes [BR:
hhw01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.9 hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing)
NCTC503_00909 (cobB)
6.3.5.11 cobyrinate a,c-diamide synthase
NCTC503_00909 (cobB)
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Motif
Pfam:
GATase_3
CbiA
AAA_26
MobB
Motif
Other DBs
NCBI-ProteinID:
VTQ86296
UniProt:
A0A4U9R5F2
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Position
1:946906..948234
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AA seq
442 aa
AA seq
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MKAIVLSSNSSGGGKTTLTLGLLKALKNRKYKVQGYKVGPDYIDPAFHSKITGIPSRNLD
LFLMGENGVKASFSRGTGNLGVVEGVMGFYDGKGIDTSYSTYEVAKTLKLPTVLVIAPKA
QVATLCAEINGILNFRDASIKGVILNNISSSYYTLLKAAIEANCNIKVFGYLPKDESLKL
ESRHLGLVQSSEIENLEEKIQHCATLLEEHVDIDSLLGEFKETEKYEDDFHIENKNIKIA
VAYDKAFSFYYRENLELLEEAGTVIYFSPLKDSNLPEDIDFLYLGGGYPEVFYDELSKNT
SMLNSIKNALDSGLRAYAECGGMMYLTKCIFKDENEEEKSPLVSFFNGNAYMTKRLQNFG
YAEIEIGEENNILPKGIQINCHEFHKSFVNNSEKTIYKVRKQSFSGREKIWTCGYVKNNT
LGAYAHIHFFGSIDFLNSLLEK
NT seq
1329 nt
NT seq
+upstream
nt +downstream
nt
atgaaggctatagttctttcatctaacagtagcggtggaggaaagaccaccttgacttta
ggacttttaaaagctttaaagaataggaagtacaaggttcagggatataaggttggacct
gattatatagatcctgcttttcatagtaaaattacaggaataccttcaagaaatctagac
cttttcctaatgggagagaatggagttaaggcaagtttttcaagaggaactggcaactta
ggagtagttgaaggggttatgggattttatgatggaaaaggcatagatactagttattcg
acttatgaagttgcaaagactttaaagcttcctacagtgcttgtaatagcacctaaggca
caggttgcaactttatgtgcagaaattaatggtattctaaattttagagatgcttctatt
aaaggtgttattctaaacaatattagcagtagctactatactcttttaaaggctgccata
gaagcaaattgtaatattaaagtctttggatacttacccaaagatgagagtcttaaactt
gaaagtaggcacctaggattagttcagagtagtgaaattgaaaatttagaagaaaagata
caacattgcgcgactcttttagaagagcatgtagatatagattctcttttaggagagttt
aaagaaacagagaaatatgaagatgattttcatatagaaaataaaaatattaaaattgca
gtagcttatgataaagcttttagcttttattatagagaaaacttagaacttttagaagag
gctggcacagttatatatttcagtccgctaaaggattctaatcttccagaggatatagat
tttctatatttaggtggagggtatccagaggtgttttatgatgaactttctaaaaatact
tctatgttaaattctattaaaaatgccttagattcaggccttagagcttatgcagaatgt
ggaggcatgatgtatcttacaaaatgcatatttaaagatgaaaatgaagaggaaaagtca
ccattagttagtttttttaatggaaatgcttacatgacaaaaagacttcaaaactttgga
tatgcagagattgaaattggggaagaaaataacatattacctaagggaattcaaataaac
tgtcatgagttccataaatcttttgtgaataatagtgaaaaaaccatatataaagttaga
aaacagagctttagtgggagagaaaagatttggacttgtggttatgtaaaaaataatacc
ctaggtgcgtatgctcatatacatttctttggaagcattgattttttaaattctttatta
gaaaaatag
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