Halorubrum lacusprofundi: Hlac_0139
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Entry
Hlac_0139 CDS
T00856
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
hla
Halorubrum lacusprofundi
Pathway
hla00010
Glycolysis / Gluconeogenesis
hla00020
Citrate cycle (TCA cycle)
hla00620
Pyruvate metabolism
hla00785
Lipoic acid metabolism
hla01100
Metabolic pathways
hla01110
Biosynthesis of secondary metabolites
hla01120
Microbial metabolism in diverse environments
hla01200
Carbon metabolism
hla01210
2-Oxocarboxylic acid metabolism
Module
hla_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
hla00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
Hlac_0139
00020 Citrate cycle (TCA cycle)
Hlac_0139
00620 Pyruvate metabolism
Hlac_0139
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Hlac_0139
Enzymes [BR:
hla01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
Hlac_0139
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Motif
Pfam:
E1_dh
DXP_synthase_N
HTH_41
Motif
Other DBs
NCBI-ProteinID:
ACM55745
UniProt:
B9LRC2
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Position
1:147209..148336
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AA seq
375 aa
AA seq
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MYEEVGSTVSVFDRAYDDPVRVLDEGGEVVGDVPDLDDEALVEMYRDMRLARHFDGRAVS
LQRQGRMGTYPPLSGQEGAQIGSATALDEDDWMVPSYREHGAALVRGLPLKQTLLYWMGH
EAGNATPEGVNVFPVAVPIASQVPHATGAAWASKLRGENDAFLCYFGDGATSEGDFHEGV
NFAGVFDTPTVFFCNNNQWAISVPRERQTRSATLAQKAEAYGIDGVQVDGMDPLAVYSVT
KAAVEKARDPETDRPRPTLIEAIQYRFGAHTTADDPTVYRDDDEVESWKRKDPIPRLERY
LRSEGVLDDERVAEIETAVETRVAEAIEAAESEVRPKPQEMFEHAYAELPPELERQYEEF
AAFREAHGDEAFLEE
NT seq
1128 nt
NT seq
+upstream
nt +downstream
nt
gtgtatgaagaggtgggttcgaccgtgagcgtgttcgacagagcgtacgacgatccggtc
cgcgttctcgacgagggcggcgaggtcgtcggcgacgtgccggacctcgacgacgaggcg
ctcgtcgagatgtaccgggacatgcggctggcgcggcacttcgacggtcgcgccgtgagc
ctccagcggcaggggcggatggggacgtatccgccgctgtccggacaggagggcgcgcag
atcggctccgcgaccgcgctcgacgaggacgactggatggtcccctcgtaccgcgagcac
ggcgcggcgctcgttcgtggactcccgctgaaacagaccctactctactggatgggccac
gaggcgggcaacgcgacgcccgagggcgtgaacgtgttcccggtcgcggtccccatcgcc
tcgcaggtcccgcacgccaccggtgcggcgtgggcgtcgaagctccgcggcgagaacgac
gcgttcctctgttacttcggggacggcgcgaccagcgagggcgacttccacgagggggtc
aacttcgcgggcgtgttcgatacgccgaccgtcttcttctgtaacaacaaccaatgggcc
atctccgtgccccgcgagcgacagacgcggagtgcgacgctggcccagaaggcggaggcg
tacgggatcgacggggtacaggtcgacgggatggacccgttggcggtgtacagcgtcacg
aaggcagccgtcgagaaggcgcgtgaccccgagaccgaccgacctcgcccgacgctgatc
gaggcgatccagtatcggttcggcgcgcacacgaccgccgacgatccgacggtctaccgc
gacgacgacgaggtcgagagctggaaacggaaggacccgatcccgcgactcgaacgctac
ctccggtccgagggcgtgctcgacgacgagcgcgtcgcggagatcgagaccgccgtcgag
acacgggtggcagaggccatcgaggcggccgagtcggaggtgcggccgaagccacaagag
atgttcgagcacgcgtacgcggagctcccacccgagctagagcggcagtacgaggagttc
gcggcgttccgcgaggcacacggcgacgaagcattcttggaggagtga
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