Hylobates moloch (silvery gibbon): 116478681
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Entry
116478681 CDS
T08803
Symbol
JAK3
Name
(RefSeq) tyrosine-protein kinase JAK3 isoform X1
KO
K11218
Janus kinase 3 [EC:
2.7.10.2
]
Organism
hmh
Hylobates moloch (silvery gibbon)
Pathway
hmh04062
Chemokine signaling pathway
hmh04151
PI3K-Akt signaling pathway
hmh04217
Necroptosis
hmh04550
Signaling pathways regulating pluripotency of stem cells
hmh04630
JAK-STAT signaling pathway
hmh04658
Th1 and Th2 cell differentiation
hmh04659
Th17 cell differentiation
hmh05161
Hepatitis B
hmh05162
Measles
hmh05166
Human T-cell leukemia virus 1 infection
hmh05169
Epstein-Barr virus infection
hmh05200
Pathways in cancer
hmh05203
Viral carcinogenesis
hmh05223
Non-small cell lung cancer
hmh05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
hmh00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
116478681 (JAK3)
04151 PI3K-Akt signaling pathway
116478681 (JAK3)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
116478681 (JAK3)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
116478681 (JAK3)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
116478681 (JAK3)
04659 Th17 cell differentiation
116478681 (JAK3)
04062 Chemokine signaling pathway
116478681 (JAK3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
116478681 (JAK3)
05203 Viral carcinogenesis
116478681 (JAK3)
09162 Cancer: specific types
05223 Non-small cell lung cancer
116478681 (JAK3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
116478681 (JAK3)
05161 Hepatitis B
116478681 (JAK3)
05162 Measles
116478681 (JAK3)
05169 Epstein-Barr virus infection
116478681 (JAK3)
09163 Immune disease
05340 Primary immunodeficiency
116478681 (JAK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hmh01001
]
116478681 (JAK3)
Enzymes [BR:
hmh01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
116478681 (JAK3)
Protein kinases [BR:
hmh01001
]
Non-receptor tyrosine kinases
JAK family [OT]
116478681 (JAK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
Jak1_Phl
Insulin
Kdo
Kinase-like
ABC1
SH2
FERM_C_FAK1
LRR_RI_capping
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
116478681
NCBI-ProteinID:
XP_032026007
EnsemblRapid:
ENSHMOG00005018172
LinkDB
All DBs
Position
Unknown
AA seq
1223 aa
AA seq
DB search
MAPPSEETPLIPQRSCSLLSTEAGALHVLLPARGPGPPQRLSFSFGDHLAEDLCVQAAKA
SGILPVYHSLFALATEDLSCWFPPSHIFSVEDASTQVLLYRIRFYFPNWFGLEKCHRFGL
RKDLASAILDLPVLEHLFAQHRSDLVSGRLPVGLSLKEQGECLSLAVLDLARMAREQAQR
PGELLKTVSYKACLPPSLRDLIQGLSFVTRRRIRRTVRRALLRVAACQADRHSLMAKYIM
DLERLDPAGAAETFHVGLPGALGGQNGLGLLRVAGDGGIAWTQGEQEVLQPFCDFPEIVD
ISIKQAPRVGPAGEHRLVTVTRTDNQILEAEFPGLPEALSFVALVDGYFRLTTDSQHFFC
KEVAPPRLLEEVAEQCHGPITLDFAINKLKTGGSRPGSYVLRRSPQDFDSFLLTVCVQTP
LGPDYKGCLIRRSPTGTFLLVGLSRPYSSLRELLATCWDGGLHVDGVAATLTSCCIPRPK
EKSNLIVVQRGHSPPTSSLVQPQSQCQLSQMTFHKIPADSLEWHENLGHGSFTKIYRGCR
HEVVDGEARKTEVLLKVMDAKHKNCMESFLEAASLMSQVSYRHLVLLHGVCMAGDSTMVQ
EFVHLGAIDMYLRKRGHLVPASWKLQVVKQLAYALNYLEDKGLPHGNVSARKVLLAREGA
DGSPPFIKLSDPGVSPAVLSLEMLTDRIPWVAPECLREAQTLSLEADKWGFGATVWEVFS
GVTMPISALDPAEKLQFYEDRQQLPAPKWTELALLIQQCMAYEPVQRPSFRAVIRDLNSL
ISSDYELLSDPTPGALAPRDGLWNGAQLYACQDPTIFEERHLKYISQLGKGNFGSVELCR
YDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRL
VMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESE
AHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYEL
FTYCDKSCSPSAEFLRMMGCERDVPALCRLLELLEEGQRLPAPPACPAEVPSWGGPGAYK
GGPRLAQAPPTAMDPRLPAWALVLLGPALVFALGPAPTPEMREKLCGHRFVRALVRVCGG
PRWSMEARRPAAGGDRELLQWLERRHLLHGLVADSNPTLGPGLQPLPQTSHHHRHHRAAA
TNPARHCCLSGCTQQDLLTLCPY
NT seq
3672 nt
NT seq
+upstream
nt +downstream
nt
atggcacctccaagtgaagagacgcccctgatccctcagcgttcatgcagcctcttgtcc
acggaggctggtgccctgcatgtgctgctgcccgctcggggccccgggcctccccagcgc
ctgtctttctcctttggggaccacttggctgaggacctgtgcgtgcaggctgccaaggcc
agcggcatcctgcctgtgtaccactccctctttgctctggccacggaggacctgtcctgc
tggttccccccaagccacatcttctccgtggaggatgccagcacccaagtcctgctctac
aggattcgcttttacttccccaattggtttgggctggagaagtgccaccgcttcgggcta
cgcaaggatttggccagcgctatccttgacctgccagtcctggagcacctctttgcccag
caccgcagtgacctggtgagtgggcgccttcccgtgggcctgagtctcaaggagcagggt
gagtgtctcagcctggccgtgctggacctggcccggatggcgcgagagcaggcccagcgg
ccgggagagctgctgaagactgtcagctacaaggcctgcctacccccaagcctgcgcgac
ctgatccagggcctgagcttcgtgacgcggaggcgtattcggaggacggtgcgcagggcc
ctgctccgcgtggccgcctgccaggcagaccggcactcgctcatggccaagtacatcatg
gacctggagcggctggatccagccggggccgccgagaccttccacgtgggcctccctggg
gcccttggtggccaaaacgggctggggctgctccgcgtggctggtgacggcggcatcgcc
tggacccagggagaacaggaggtcctccagcccttctgcgactttccagagatcgtagac
attagcatcaagcaggccccgcgcgttggcccggccggggagcatcgcctggtcactgtt
actaggacagacaaccagattttggaggccgagttcccagggctgcccgaggctctgtct
ttcgtggcgctcgtggacggctacttccggctgaccacggactcccagcacttcttctgc
aaggaggtggcaccgccgaggctgctggaggaagtggctgagcagtgccatggccccatc
actctggactttgccatcaacaagcttaagactgggggctcacgtcctggctcctatgtt
ctccgccgcagcccccaggattttgacagcttcctcctcactgtctgtgtccagaccccc
cttggtcctgattataagggctgcctcatccggcgcagccccacaggaaccttccttctg
gttggcctcagtcgaccctacagcagtcttcgagagctcctggcaacctgctgggatggg
gggctgcacgtagatggggtggcagcgaccctcacctcctgttgtatccccagacccaaa
gaaaagtccaacctgatcgtggtgcagagaggtcacagcccacccacatcatccttggtt
cagccccaatcccaatgccagctgagtcagatgacgtttcacaagatccctgctgacagc
ctggagtggcatgagaacctgggccatgggtccttcaccaagatttaccggggctgtcgc
catgaggtggtggatggggaggcccgaaagacagaggtgctgctgaaggtgatggatgct
aagcacaagaactgcatggagtcattcctggaagcagcgagcttgatgagccaagtgtca
taccggcatctcgtgctgctccacggcgtgtgcatggctggagacagcaccatggtgcag
gaatttgtacacctgggggcgatagacatgtatctacgaaaacgtggccacctggtgcca
gccagctggaagctacaggtggtcaaacagctggcctacgccctcaattatctggaggac
aaaggcctcccccacggcaatgtctctgcccggaaggtgctcctggctcgggagggggct
gatgggagcccacccttcatcaagctgagtgaccctggggtcagccccgctgtgttaagc
ctggagatgctcaccgacaggatcccctgggtggcccccgagtgtctccgggaggcccag
acacttagcttggaagctgacaagtggggcttcggcgccacggtctgggaagtgtttagt
ggcgtcaccatgcccatcagcgccctggatcctgctgagaaactccaattttatgaggac
cggcagcagctgccagcccccaagtggacagagctggccctgctgattcaacagtgcatg
gcctatgagccggtccagaggccctccttccgagctgtcattcgtgacctcaatagcctc
atctcttcagactatgagctcctctcagaccccacacctggtgccctggcacctcgtgat
gggctgtggaatggtgcccagctctatgcctgccaagaccccacgatcttcgaggagaga
cacctcaagtacatctcacagctgggcaagggcaactttggcagcgtggagctgtgccgc
tatgacccgctaggcgacaatacaggtgccctggtggctgtaaaacagctgcagcacagt
ggcccagaccagcagagggactttcagcgggagattcagatcctcaaagcactgcacagt
gatttcattgtcaagtatcgtggtgtcagctacggcccgggccgccagagcctgcggcta
gtcatggagtacctgcccagcggctgcttgcgcgacttcctgcagcggcaccgtgcgcgc
ctcgacgccagccgccttcttctctactcctcgcagatctgcaagggcatggagtacctg
ggctcccgccgctgcgtgcaccgcgacctggccgctcgaaacatccttgtggagagcgag
gcacacgtcaagatcgctgacttcggcctagctaagctgctcccgcttgacaaagactac
tacgtggtccgcgagccaggccagagccccattttctggtatgcccccgaatccctctcg
gacaacatcttctctcgccagtcagacgtctggagcttcggggtcgtcctgtacgagctc
ttcacctactgcgacaaaagctgcagcccctcggccgagttcctgcgaatgatgggatgt
gagcgggatgtccccgccctctgccgcctcctggaactgctggaggagggccagaggctg
ccggcgcctcctgcctgccctgctgaggtccccagctggggcggcccaggcgcctataaa
gggggtccccgcttggcccaggcgccacccaccgccatggacccccgtctgcctgcctgg
gcgctggtgctgctgggccctgccctggtgttcgcgttgggccccgcgcccaccccagag
atgcgtgagaagttgtgcggccaccgcttcgtgcgcgcgctggtgcgcgtgtgcgggggc
ccccgctggtccatggaggccaggaggcctgcggctggaggcgaccgtgagttgctacag
tggctggagagacgacatctgctccatgggctggtggccgacagtaatcccacgctggga
cctggcctgcagcccctgccccagacctctcaccatcaccgccaccaccgtgcagctgcc
accaaccctgcacgccactgctgcctcagtggctgtacccaacaagacctgctgaccctc
tgtccctactga
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integrated database retrieval system
