Hemiscyllium ocellatum (epaulette shark): 132832492
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Entry
132832492 CDS
T09720
Symbol
hsd17b8
Name
(RefSeq) estradiol 17-beta-dehydrogenase 8 isoform X1
KO
K13370
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) / 3-oxoacyl-[acyl-carrier protein] reductase alpha subunit [EC:
1.1.1.62
1.1.1.239
]
Organism
hoc
Hemiscyllium ocellatum (epaulette shark)
Pathway
hoc00061
Fatty acid biosynthesis
hoc00140
Steroid hormone biosynthesis
hoc01100
Metabolic pathways
hoc01212
Fatty acid metabolism
Module
hoc_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
hoc00001
]
09100 Metabolism
09103 Lipid metabolism
00061 Fatty acid biosynthesis
132832492 (hsd17b8)
00140 Steroid hormone biosynthesis
132832492 (hsd17b8)
Enzymes [BR:
hoc01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
132832492 (hsd17b8)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
132832492 (hsd17b8)
BRITE hierarchy
Motif
Pfam:
adh_short_C2
adh_short
KR
Epimerase
3Beta_HSD
Polysacc_synt_2
3HCDH_N
GDP_Man_Dehyd
TrkA_N
RmlD_sub_bind
fvmX6
DUF4180
Motif
Other DBs
NCBI-GeneID:
132832492
NCBI-ProteinID:
XP_060706527
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All DBs
Position
35:complement(30545245..30607149)
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AA seq
254 aa
AA seq
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MAALRLSSRLALVTGGGSGIGRAVCQRFAKEGAAVAVVDINQGAAEETLRSLPSNQQQQQ
HSLFVTDVTSSERVRSLMADIQAQFSRPPCIAVNCAGITADGLLLKMESDAFDRVLAVNL
KGTFLVTQAVARALVASGAKTGSIINVGSIVGKVGNLGQANYTASKAAVVALTKTSAKEL
ARFGIRCNTVLPGFIDTPMAAKVPQKVLDKVVQLVPMARLGEPCEVASACTFLASDESSY
ITGASLEVTGGLFM
NT seq
765 nt
NT seq
+upstream
nt +downstream
nt
atggcggcgctgcggctcagctcgcgcctggcgctggtgacaggcggtggcagtgggata
gggcgcgctgtgtgccagcgttttgcgaaggagggagccgcggtggcagtggtggacatc
aaccaaggggcagctgaggaaaccctgcggagcctgccctccaatcagcagcagcagcag
cactcgctgtttgtcaccgacgtgacctcctctgagcgtgtccgcagcctcatggctgat
attcaggcgcagttttcccgccctccctgcatcgcagtgaactgcgccggcatcaccgca
gacgggctgctgctgaagatggagagcgacgcgttcgaccgggttttggcggtcaatctg
aagggtaccttcctggtgacccaggcagttgccagggcgttggttgctagcggcgccaag
acaggttccattatcaacgtgggcagcatcgtgggaaaggttggaaatttgggacaggcc
aattacacagcgtcaaaagctgctgttgtggcactgacgaagaccagtgcgaaagaactg
gccaggttcggaatccgctgtaacaccgtcctcccgggattcatcgatacccccatggca
gccaaggtccctcagaaggtgctggacaaggtggtacagttggtgccgatggcccgcctg
ggagagccctgtgaggtagccagcgcctgtaccttcctggcctccgacgagagcagctac
atcactggagccagtctggaggtgacaggaggactcttcatgtga
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integrated database retrieval system
