Halomonas profundus: LMS44_12625
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Entry
LMS44_12625 CDS
T08361
Symbol
folC
Name
(GenBank) bifunctional tetrahydrofolate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
hpro
Halomonas profundus
Pathway
hpro00790
Folate biosynthesis
hpro01100
Metabolic pathways
hpro01240
Biosynthesis of cofactors
Module
hpro_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
hpro00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
LMS44_12625 (folC)
Enzymes [BR:
hpro01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
LMS44_12625 (folC)
6.3.2.17 tetrahydrofolate synthase
LMS44_12625 (folC)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
UEQ02147
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Position
complement(2790730..2792088)
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AA seq
452 aa
AA seq
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MTIRAMPDSLQTPSLPLYSLQQWLQHLETLHPVGIDMGLERVSQVAKRMGLLSSPIAPRV
ITVAGTNGKGSTLAMIDSVARAHGWRVGTYTSPHLLRYNERVKIDDQEADDQLLVQGFER
VEQARLQGSEISLTYFEAGTLCGLWCLANAKLDLAVLEVGLGGRLDAVNIIDADVAIVTT
IAQDHANFLGTDLAQIGREKAGIFRANRPAVLGSQTLPSSVAECAQVLAAPMFCLGQQFA
HQTMASEPSQWRWQGQHPDGQRIVIDELPEPGLPIDNAATALQALVLAGLGLEAARVQAA
LSSVQLPGRLQWIGPWCLDVGHNPHAAEYVVRHLPQPPEGGRQWGLIGMLNDKDIDGVIQ
TLASRISDWVCVSLSGERGCQASELSQRIIAQGGRVHFSADSPQAGVDWLANMLTPNDRV
LATGSFFTVAALLARPLPTGAASLDGDGNEIR
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgaccattcgcgcaatgcctgactctctgcagacaccttctttgccgctctactctttg
caacagtggctccagcatttggaaacgctgcatccggtagggattgatatgggcctggag
cgggtctcgcaggtggctaaacggatggggctgctttcaagccccatcgccccccgcgtt
attacggtagcaggcaccaacggcaagggctcaacccttgccatgattgatagcgttgcc
cgtgcccatggttggcgagtgggtacctacacttctccccatttattgcgctacaacgag
cgcgttaaaatcgatgatcaggaagccgacgaccaactgctggtgcaaggctttgagcgg
gttgagcaggcacgattgcagggcagtgaaatcagcctgacctattttgaagcggggaca
ctgtgcggactgtggtgcttggccaatgcaaagcttgatcttgcggtgctagaagtgggg
ctgggtggtcgccttgatgcagtcaatattattgatgcggatgtggccattgttaccact
attgctcaggatcacgctaactttttaggcaccgatttagcccagattgggcgtgaaaaa
gccggtatttttcgtgccaatcgtcccgccgtgctaggtagccaaacgttaccttccagt
gtcgctgaatgtgctcaggtgctggcggcgcctatgttttgtttgggccagcaatttgcc
catcagacgatggcttctgagccttcgcaatggcgctggcaggggcagcatccggatggt
caacgcattgttattgacgagcttcccgagccggggctgcctatcgataacgccgccact
gctttgcaggcgcttgtgcttgcagggcttgggttggaagcggcgcgcgtgcaagctgcg
ttgagttctgtgcagttgccggggcggctgcaatggattgggccttggtgcctggatgta
ggtcataatcctcatgctgccgagtatgtcgttcgccatttgccgcaacctccggaaggt
ggtcggcagtggggccttattggcatgttgaatgataaggatattgacggtgtcatacag
acgttagcgtctcgcattagtgattgggtgtgcgtgtcgttgagcggagagcgaggttgc
caggcaagcgagttgtcgcaacgtattatagctcagggagggcgggtgcattttagtgct
gattcgccgcaagcaggcgtcgattggctcgctaacatgttaacgcccaatgatcgtgtc
ttggccaccggatcgttctttacagtagcggcactgttagctcggccactgccaacaggc
gctgcgtcgcttgatggagacggaaatgaaatacggtaa
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