Homo sapiens (human): 116444
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Entry
116444 CDS
T01001
Symbol
GRIN3B, GluN3B, NR3B
Name
(RefSeq) glutamate ionotropic receptor NMDA type subunit 3B
KO
K05214
glutamate receptor ionotropic, NMDA 3B
Organism
hsa
Homo sapiens (human)
Pathway
hsa04020
Calcium signaling pathway
hsa04024
cAMP signaling pathway
hsa04080
Neuroactive ligand-receptor interaction
hsa04724
Glutamatergic synapse
hsa05017
Spinocerebellar ataxia
hsa05020
Prion disease
hsa05030
Cocaine addiction
hsa05031
Amphetamine addiction
hsa05033
Nicotine addiction
hsa05034
Alcoholism
Drug target
Dalzanemdor:
D12788
Felbamate:
D00536
<US>
Orphenadrine (
DG01252
):
D08305
Orphenadrine (chloride):
D02599
Orphenadrine (citrate):
D00774
<US>
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
116444 (GRIN3B)
04024 cAMP signaling pathway
116444 (GRIN3B)
09133 Signaling molecules and interaction
04080 Neuroactive ligand-receptor interaction
116444 (GRIN3B)
09150 Organismal Systems
09156 Nervous system
04724 Glutamatergic synapse
116444 (GRIN3B)
09160 Human Diseases
09164 Neurodegenerative disease
05017 Spinocerebellar ataxia
116444 (GRIN3B)
05020 Prion disease
116444 (GRIN3B)
09165 Substance dependence
05030 Cocaine addiction
116444 (GRIN3B)
05031 Amphetamine addiction
116444 (GRIN3B)
05033 Nicotine addiction
116444 (GRIN3B)
05034 Alcoholism
116444 (GRIN3B)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
hsa04040
]
116444 (GRIN3B)
Ion channels [BR:
hsa04040
]
Ligand-gated channels
Glutamate (ionotropic)
116444 (GRIN3B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Lig_chan
Lig_chan-Glu_bd
SBP_bac_3
ANF_receptor
Motif
Other DBs
NCBI-GeneID:
116444
NCBI-ProteinID:
NP_619635
OMIM:
606651
HGNC:
16768
Ensembl:
ENSG00000116032
UniProt:
O60391
Q5F0I5
LinkDB
All DBs
Position
19:1000419..1009732
Genome browser
AA seq
1043 aa
AA seq
DB search
MEFVRALWLGLALALGPGSAGGHPQPCGVLARLGGSVRLGALLPRAPLARARARAALARA
ALAPRLPHNLSLELVVAAPPARDPASLTRGLCQALVPPGVAALLAFPEARPELLQLHFLA
AATETPVLSLLRREARAPLGAPNPFHLQLHWASPLETLLDVLVAVLQAHAWEDVGLALCR
TQDPGGLVALWTSRAGRPPQLVLDLSRRDTGDAGLRARLAPMAAPVGGEAPVPAAVLLGC
DIARARRVLEAVPPGPHWLLGTPLPPKALPTAGLPPGLLALGEVARPPLEAAIHDIVQLV
ARALGSAAQVQPKRALLPAPVNCGDLQPAGPESPGRFLARFLANTSFQGRTGPVWVTGSS
QVHMSRHFKVWSLRRDPRGAPAWATVGSWRDGQLDLEPGGASARPPPPQGAQVWPKLRVV
TLLEHPFVFARDPDEDGQCPAGQLCLDPGTNDSATLDALFAALANGSAPRALRKCCYGYC
IDLLERLAEDTPFDFELYLVGDGKYGALRDGRWTGLVGDLLAGRAHMAVTSFSINSARSQ
VVDFTSPFFSTSLGIMVRARDTASPIGAFMWPLHWSTWLGVFAALHLTALFLTVYEWRSP
YGLTPRGRNRSTVFSYSSALNLCYAILFRRTVSSKTPKCPTGRLLMNLWAIFCLLVLSSY
TANLAAVMVGDKTFEELSGIHDPKLHHPAQGFRFGTVWESSAEAYIKKSFPDMHAHMRRH
SAPTTPRGVAMLTSDPPKLNAFIMDKSLLDYEVSIDADCKLLTVGKPFAIEGYGIGLPQN
SPLTSNLSEFISRYKSSGFIDLLHDKWYKMVPCGKRVFAVTETLQMSIYHFAGLFVLLCL
GLGSALLSSLGEHAFFRLALPRIRKGSRLQYWLHTSQKIHRALNTEPPEGSKEETAEAEP
SGPEVEQQQQQQDQPTAPEGWKRARRAVDKERRVRFLLEPAVVVAPEADAEAEAAPREGP
VWLCSYGRPPAARPTGAPQPGELQELERRIEVARERLRQALVRRGQLLAQLGDSARHRPR
RLLQARAAPAEAPPHSGRPGSQE
NT seq
3132 nt
NT seq
+upstream
nt +downstream
nt
atggagtttgtgcgggcgctgtggctgggcctggcgctggcgctggggccggggtccgcg
gggggccaccctcagccgtgcggcgtcctggcgcgcctcgggggctccgtgcgcctgggc
gccctcctgccccgcgcgcctctcgcccgcgcccgcgcccgcgccgccctggcccgggcc
gccctggcgccgcggctgccgcacaacctgagcttggagctggtggtcgccgcgcccccc
gcccgcgaccccgcctcgctgacccgcggcctgtgccaggcgctggtgcctccgggcgtg
gcggccctgctcgcctttcccgaggctcggcccgagctgctgcagctgcacttcctggcg
gcggccaccgagacccccgtgctcagcctgctgcggcgggaggcgcgcgcgcccctcgga
gccccgaacccattccacctgcagctgcactgggccagccccctggagacgctgctggat
gtgctggtggcggtgctgcaggcgcacgcctgggaagacgtcggcctggccctgtgccgc
actcaggaccccggcggcctggtggccctctggacaagccgggctggccggcccccacag
ctggtcctggacctaagccggcgggacacgggagatgcaggactgcgggcacgcctggcc
ccgatggcggcgccagtggggggtgaagcaccggtacccgcggcggtcctcctcggctgt
gacatcgcccgtgcccgtcgggtgctggaggccgtacctcccggcccccactggctgttg
gggacaccactgccgcccaaggccctgcccaccgcggggctgccaccagggctgctggcg
ctgggcgaggtggcacgacccccgctggaggccgccatccatgacattgtgcaactggtg
gcccgggcgctgggcagtgcggcccaggtgcagccgaagcgagccctcctccccgccccg
gtcaactgcggggacctgcagccggccgggcccgagtccccggggcgcttcttggcacgg
ttcctggccaacacgtccttccagggccgcacgggccccgtgtgggtgacaggcagctcc
caggtacacatgtctcggcactttaaggtgtggagccttcgccgggacccacggggcgcc
ccggcctgggccacggtgggcagctggcgggacggccagctggacttggaaccgggaggt
gcctctgcacggcccccgcccccacagggtgcccaggtctggcccaagctgcgtgtggta
acgctgttggaacacccatttgtgtttgcccgtgatccagacgaagacgggcagtgccca
gcggggcagctgtgcctggaccctggcaccaacgactcggccaccctggacgcactgttc
gccgcgctggccaacggctcagcgccccgtgccctgcgcaagtgctgctacggctactgc
attgacctgctggagcggctggcggaggacacgcccttcgacttcgagctgtacctcgtg
ggtgacggcaagtacggcgccctgcgggacggccgctggaccggcctggtcggggacctg
ctggccggccgggcccacatggcggtcaccagcttcagtatcaactccgcccgctcacag
gtggtggacttcaccagccccttcttctccaccagcctgggcatcatggtgcgggcacgg
gacacggcctcacccatcggtgcctttatgtggcccctgcactggtccacgtggctgggc
gtctttgcggccctgcacctcaccgcgctcttcctcaccgtgtacgagtggcgtagcccc
tacggcctcacgccacgtggccgcaaccgcagcaccgtcttctcctactcctcagccctc
aacctgtgctacgccatcctcttcagacgcaccgtgtccagcaagacgcccaagtgcccc
acgggccgcctgctcatgaacctctgggccatcttctgcctgctggtgctgtccagctac
acggccaacctggctgccgtcatggtcggggacaagaccttcgaggagctgtcggggatc
cacgaccccaagctgcaccacccggcgcagggcttccgcttcggcaccgtgtgggagagc
agcgccgaggcgtacatcaagaagagcttccccgacatgcacgcacacatgcggcgccac
agcgcgcccaccacgccccgcggcgtcgccatgctcacgagcgacccccccaagctcaac
gccttcatcatggacaagtcgctcctggactacgaggtctccatcgacgccgactgcaaa
ctgctgaccgtgggaaagcccttcgccattgagggctatgggatcggactgccccagaac
tcgccgctcacctccaacctgtccgagttcatcagccgctacaagtcctccggcttcatc
gacctgctccacgacaagtggtacaagatggtgccttgcggcaagcgggtctttgcggtt
acagagaccctgcagatgagcatctaccacttcgcgggcctcttcgtgttgctgtgcctg
ggcctgggcagcgctctgctcagctcgctgggcgagcacgccttcttccgcctggcgctg
ccgcgcatccgcaaggggagcaggctgcagtactggctgcacaccagccagaaaatccac
cgcgccctcaacacggagccaccagaggggtcgaaggaggagacggcagaggcggagccc
agcggccccgaggtggagcagcagcagcagcagcaggaccagccaacggctccggagggc
tggaaacgggcgcgccgggccgtggacaaggagcgccgcgtgcgcttcctgctggagccc
gccgtggttgtggcacccgaagcggacgcggaggcggaggctgcgccgcgagagggcccc
gtctggctgtgctcctacggccgcccgcccgccgcaaggcccacgggggccccccagccc
ggggagctgcaggagctggagcgccgcatcgaagtcgcgcgtgagcggctccgccaggcc
ctggtgcggcgcggccagctcctggcacagctcggggacagcgcacgtcaccggcctcgg
cgcttgcttcaggccagagcggcccccgcggaggccccaccacactctggccgaccgggg
agccaggaatga
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integrated database retrieval system
