Homo sapiens (human): 121391
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Entry
121391 CDS
T01001
Symbol
KRT74, ADWH, ECTD7, HTSS2, HYPT3, K6IRS4, KRT5C, KRT6IRS4
Name
(RefSeq) keratin 74
KO
K07605
type II keratin, basic
Organism
hsa
Homo sapiens (human)
Disease
H00649
Ectodermal dysplasia, hair-nail type
H00667
Woolly hair
H00786
Hypotrichosis
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
hsa04812
]
121391 (KRT74)
04147 Exosome [BR:
hsa04147
]
121391 (KRT74)
Cytoskeleton proteins [BR:
hsa04812
]
Eukaryotic cytoskeleton proteins
Intermediate filaments
Intermediate filaments
Types I and II: Acidic and basic keratins
121391 (KRT74)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of epithelial cells
121391 (KRT74)
Exosomal proteins of other body fluids (saliva and urine)
121391 (KRT74)
Exosomal proteins of colorectal cancer cells
121391 (KRT74)
Exosomal proteins of bladder cancer cells
121391 (KRT74)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Filament
Keratin_2_head
CENP-F_leu_zip
Golgin_A5
TPR_MLP1_2
DUF6856
DUF4407
COA8
Baculo_PEP_C
Motif
Other DBs
NCBI-GeneID:
121391
NCBI-ProteinID:
NP_778223
OMIM:
608248
HGNC:
28929
Ensembl:
ENSG00000170484
UniProt:
Q7RTS7
LinkDB
All DBs
Position
12:complement(52565782..52573843)
Genome browser
AA seq
529 aa
AA seq
DB search
MSRQLNIKSSGDKGNFSVHSAVVPRKAVGSLASYCAAGRGAGAGFGSRSLYSLGGNRRIS
FNVAGGGVRAGGYGFRPGSGYGGGRASGFAGSMFGSVALGPACLSVCPPGGIHQVTVNKS
LLAPLNVELDPEIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQLDL
NNCKKNLEPILEGYISNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTTA
ENEFVVLKKDADAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSMD
NNRDLDLDSIIAEVRMHYEEIALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMVE
LNRLIQRIRCEIGNVKKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELAR
MLREYQELMSLKLALDMEIATYRKLLEGEECRMSGENPSSVSISVISSSSYSYHHPSSAG
VDLGASAVAGSSGSTQSGQTKTTEARGGDLKDTQGKSTPASIPARKATR
NT seq
1590 nt
NT seq
+upstream
nt +downstream
nt
atgagtcggcaactgaacatcaagtccagtggtgacaagggcaacttcagtgtgcattcg
gcagtggtgccaaggaaggctgtgggtagcctggcttcttactgtgcagctggcagaggg
gctggcgctggctttggcagtcggagcctctatagccttggagggaatcggcgtatttct
ttcaatgtggctggtggcggcgttcgggctggaggttacggcttcaggcctggctctggg
tatggagggggccgggccagtggctttgctggcagtatgtttggcagtgtggccctgggg
cctgcatgtttgtctgtgtgcccacctgggggcatccaccaggtcactgtcaacaagagc
ctcttggcccccctcaacgtggagctggaccctgagatccagaaggtgcgcgcccaggag
cgggaacagatcaaggtgctgaacgacaagttcgcctccttcattgacaaggtacgcttc
ctagagcagcagaaccaggttctagaaaccaagtgggagctgctgcagcagctggacctg
aacaactgcaagaagaacctggagcccatccttgagggctacatcagcaacctgcggaag
cagctggagacactgtctggggacagggtgaggctggactcggagctgagaagcatgagg
gatctggtggaggactataagaagagatatgaagtggagattaaccggcgcacgacagca
gagaatgagtttgtggtgcttaagaaggatgcagatgcagcctacgcagtcaaggtggag
cttcaggccaaagtggactcactggacaaagaaatcaagttcctcaagtgtctgtatgat
gcagagatcgctcagatccagactcacgccagtgagacctctgtcatcctgtccatggac
aacaaccgggacctggaccttgacagcatcatcgctgaggtccgcatgcattatgaggag
atcgccctgaagagcaaggccgaggccgaggccctgtaccagaccaagatccaggagctg
cagctggcagccagtcggcatggtgacgacctgaaacacaccaggagcgagatggtggag
ctgaaccggctcatccagaggatccggtgtgagatcgggaatgtgaagaagcagcgtgcc
agcctggagacggccatcgctgacgctgagcagcggggagacaatgccctgaaggatgcc
caggccaagctggatgagctggagggcgccctgcaccaggccaaggaggagctggcgcgg
atgctgcgcgagtaccaggagctcatgagcctgaaactggccctggacatggagattgcc
acctaccgcaagctgctggagggcgaggagtgcaggatgtctggtgagaatccatcctct
gtgagcatctctgtcatcagcagtagcagctacagctaccaccaccccagctctgcgggt
gttgaccttggggccagcgctgtggcaggcagctctggcagcacccagagcgggcagacc
aagaccacagaggcgcgagggggagacctcaaggacacccagggcaagagcaccccagcc
agcatcccagcaaggaaagccacccgctag
DBGET
integrated database retrieval system
