Homo sapiens (human): 27430
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Entry
27430 CDS
T01001
Symbol
MAT2B, MAT-II, MATIIbeta, Nbla02999, SDR23E1, TGR
Name
(RefSeq) methionine adenosyltransferase 2 non-catalytic beta subunit
KO
K00789
S-adenosylmethionine synthetase [EC:
2.5.1.6
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00270
Cysteine and methionine metabolism
hsa01100
Metabolic pathways
hsa01230
Biosynthesis of amino acids
hsa01240
Biosynthesis of cofactors
Module
hsa_M00034
Methionine salvage pathway
hsa_M00035
Methionine degradation
Network
nt06030
Methionine metabolism
Element
N01607
Methionine degradation
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
27430 (MAT2B)
Enzymes [BR:
hsa01000
]
2. Transferases
2.5 Transferring alkyl or aryl groups, other than methyl groups
2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
2.5.1.6 methionine adenosyltransferase
27430 (MAT2B)
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Gene cluster
GFIT
Motif
Pfam:
RmlD_sub_bind
Epimerase
GDP_Man_Dehyd
Polysacc_synt_2
NAD_binding_4
DapB_N
Motif
Other DBs
NCBI-GeneID:
27430
NCBI-ProteinID:
NP_037415
OMIM:
605527
HGNC:
6905
Ensembl:
ENSG00000038274
UniProt:
Q9NZL9
A0A140VJP2
Structure
PDB
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All DBs
Position
5:163503064..163519354
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AA seq
334 aa
AA seq
DB search
MVGREKELSIHFVPGSCRLVEEEVNIPNRRVLVTGATGLLGRAVHKEFQQNNWHAVGCGF
RRARPKFEQVNLLDSNAVHHIIHDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNL
AKEAAAVGAFLIYISSDYVFDGTNPPYREEDIPAPLNLYGKTKLDGEKAVLENNLGAAVL
RIPILYGEVEKLEESAVTVMFDKVQFSNKSANMDHWQQRFPTHVKDVATVCRQLAEKRML
DPSIKGTFHWSGNEQMTKYEMACAIADAFNLPSSHLRPITDSPVLGAQRPRNAQLDCSKL
ETLGIGQRTPFRIGIKESLWPFLIDKRWRQTVFH
NT seq
1005 nt
NT seq
+upstream
nt +downstream
nt
atggtggggcgggagaaagagctctctatacactttgttcccgggagctgtcggctggtg
gaggaggaagttaacatccctaataggagggttctggttactggtgccactgggcttctt
ggcagagctgtacacaaagaatttcagcagaataattggcatgcagttggctgtggtttc
agaagagcaagaccaaaatttgaacaggttaatctgttggattctaatgcagttcatcac
atcattcatgattttcagccccatgttatagtacattgtgcagcagagagaagaccagat
gttgtagaaaatcagccagatgctgcctctcaacttaatgtggatgcttctgggaattta
gcaaaggaagcagctgctgttggagcatttctcatctacattagctcagattatgtattt
gatggaacaaatccaccttacagagaggaagacataccagctcccctaaatttgtatggc
aaaacaaaattagatggagaaaaggctgtcctggagaacaatctaggagctgctgttttg
aggattcctattctgtatggggaagttgaaaagctcgaagaaagtgctgtgactgttatg
tttgataaagtgcagttcagcaacaagtcagcaaacatggatcactggcagcagaggttc
cccacacatgtcaaagatgtggccactgtgtgccggcagctagcagagaagagaatgctg
gatccatcaattaagggaacctttcactggtctggcaatgaacagatgactaagtatgaa
atggcatgtgcaattgcagatgccttcaacctccccagcagtcacttaagacctattact
gacagccctgtcctaggagcacaacgtccgagaaatgctcagcttgactgctccaaattg
gagaccttgggcattggccaacgaacaccatttcgaattggaatcaaagaatcactttgg
cctttcctcattgacaagagatggagacaaacggtctttcattag
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