Homo sapiens (human): 4144
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Entry
4144 CDS
T01001
Symbol
MAT2A, MATA2, MATII, SAMS2
Name
(RefSeq) methionine adenosyltransferase 2A
KO
K00789
S-adenosylmethionine synthetase [EC:
2.5.1.6
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00270
Cysteine and methionine metabolism
hsa01100
Metabolic pathways
hsa01230
Biosynthesis of amino acids
hsa01240
Biosynthesis of cofactors
Module
hsa_M00034
Methionine salvage pathway
hsa_M00035
Methionine degradation
Network
nt06030
Methionine metabolism
Element
N01607
Methionine degradation
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
4144 (MAT2A)
Enzymes [BR:
hsa01000
]
2. Transferases
2.5 Transferring alkyl or aryl groups, other than methyl groups
2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
2.5.1.6 methionine adenosyltransferase
4144 (MAT2A)
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Gene cluster
GFIT
Motif
Pfam:
S-AdoMet_synt_C
S-AdoMet_synt_M
S-AdoMet_synt_N
AdoMet_Synthase
Motif
Other DBs
NCBI-GeneID:
4144
NCBI-ProteinID:
NP_005902
OMIM:
601468
HGNC:
6904
Ensembl:
ENSG00000168906
UniProt:
P31153
A0A140VJP5
Structure
PDB
LinkDB
All DBs
Position
2:85539168..85545281
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AA seq
395 aa
AA seq
DB search
MNGQLNGFHEAFIEEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVA
KTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQG
VHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDS
KTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDT
IYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARW
VAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVI
VRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY
NT seq
1188 nt
NT seq
+upstream
nt +downstream
nt
atgaacggacagctcaacggcttccacgaggcgttcatcgaggagggcacattccttttc
acctcagagtcggtcggggaaggccacccagataagatttgtgaccaaatcagtgatgct
gtccttgatgcccaccttcagcaggatcctgatgccaaagtagcttgtgaaactgttgct
aaaactggaatgatccttcttgctggggaaattacatccagagctgctgttgactaccag
aaagtggttcgtgaagctgttaaacacattggatatgatgattcttccaaaggttttgac
tacaagacttgtaacgtgctggtagccttggagcaacagtcaccagatattgctcaaggt
gttcatcttgacagaaatgaagaagacattggtgctggagaccagggcttaatgtttggc
tatgccactgatgaaactgaggagtgtatgcctttaaccattgtcttggcacacaagcta
aatgccaaactggcagaactacgccgtaatggcactttgccttggttacgccctgattct
aaaactcaagttactgtgcagtatatgcaggatcgaggtgctgtgcttcccatcagagtc
cacacaattgttatatctgttcagcatgatgaagaggtttgtcttgatgaaatgagggat
gccctaaaggagaaagtcatcaaagcagttgtgcctgcgaaataccttgatgaggataca
atctaccacctacagccaagtggcagatttgttattggtgggcctcagggtgatgctggt
ttgactggacgcaaaatcattgtggacacttatggcggttggggtgctcatggaggaggt
gccttttcaggaaaggattataccaaggtcgaccgttcagctgcttatgctgctcgttgg
gtggcaaaatcccttgttaaaggaggtctgtgccggagggttcttgttcaggtctcttat
gctattggagtttctcatccattatctatctccattttccattatggtacctctcagaag
agtgagagagagctattagagattgtgaagaagaatttcgatctccgccctggggtcatt
gtcagggatctggatctgaagaagccaatttatcagaggactgcagcctatggccacttt
ggtagggacagcttcccatgggaagtgcccaaaaagcttaaatattga
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integrated database retrieval system
