Homo sapiens (human): 441925
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Entry
441925 CDS
T01001
Symbol
BECN2, BECN1L1, BECN1P1
Name
(RefSeq) beclin 2
KO
K08334
beclin
Organism
hsa
Homo sapiens (human)
Pathway
hsa04136
Autophagy - other
hsa04137
Mitophagy - animal
hsa04140
Autophagy - animal
hsa04215
Apoptosis - multiple species
hsa04371
Apelin signaling pathway
hsa05010
Alzheimer disease
hsa05014
Amyotrophic lateral sclerosis
hsa05016
Huntington disease
hsa05017
Spinocerebellar ataxia
hsa05022
Pathways of neurodegeneration - multiple diseases
hsa05131
Shigellosis
hsa05167
Kaposi sarcoma-associated herpesvirus infection
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
441925 (BECN2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
441925 (BECN2)
04136 Autophagy - other
441925 (BECN2)
04137 Mitophagy - animal
441925 (BECN2)
09143 Cell growth and death
04215 Apoptosis - multiple species
441925 (BECN2)
09160 Human Diseases
09172 Infectious disease: viral
05167 Kaposi sarcoma-associated herpesvirus infection
441925 (BECN2)
09171 Infectious disease: bacterial
05131 Shigellosis
441925 (BECN2)
09164 Neurodegenerative disease
05010 Alzheimer disease
441925 (BECN2)
05014 Amyotrophic lateral sclerosis
441925 (BECN2)
05016 Huntington disease
441925 (BECN2)
05017 Spinocerebellar ataxia
441925 (BECN2)
05022 Pathways of neurodegeneration - multiple diseases
441925 (BECN2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
441925 (BECN2)
03029 Mitochondrial biogenesis [BR:
hsa03029
]
441925 (BECN2)
Membrane trafficking [BR:
hsa04131
]
Autophagy
Autophagosome formation proteins
PI3K complex
441925 (BECN2)
Mitochondrial biogenesis [BR:
hsa03029
]
Mitochondrial quality control factors
Mitophagy factors
Autophagy-related proteins
441925 (BECN2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
APG6
APG6_N
GAS
BH3
DUF3450
Motif
Other DBs
NCBI-GeneID:
441925
NCBI-ProteinID:
NP_001277622
OMIM:
615687
HGNC:
38606
Ensembl:
ENSG00000196289
UniProt:
A8MW95
Structure
PDB
LinkDB
All DBs
Position
1:241957767..241959062
Genome browser
AA seq
431 aa
AA seq
DB search
MSSIRFLCQRCHQALKLSGSSESRSLPAAPAPTSGQAEPGDTREPGVTTREVTDAEEQQD
GASSRSPPGDGSVSKGHANIFTLLGELGAMHMLSSIQKAAGDIFDIVSGQAVVDHPLCEE
CTDSLLEQLDIQLALTEADSQNYQRCLETGELATSEDEAAALRAELRDLELEEARLVQEL
EDVDRNNARAAADLQAAQAEAAELDQQERQHYRDYSALKRQQLELLDQLGNVENQLQYAR
VQRDRLKEINCFTATFEIWVEGPLGVINNFRLGRLPTVRVGWNEINTAWGQAALLLLTLA
NTIGLQFQRYRLIPCGNHSYLKSLTDDRTELPLFCYGGQDVFLNNKYDRAMVAFLDCMQQ
FKEEAEKGELGLSLPYGIQVETGLMEDVGGRGECYSIRTHLNTQELWTKALKFMLINFKW
SLIWVASRYQK
NT seq
1296 nt
NT seq
+upstream
nt +downstream
nt
atgtcttccatccgcttcctgtgccagcgctgccaccaggccctgaagctgagcggctcc
tcggagtctaggagcctccctgcagccccggcgcccacctctgggcaggctgagcccgga
gacacccgggagcccggcgtcaccaccagggaggtgacagacgctgaggagcaacaggac
ggtgcctctagcagatcccctccaggcgatggcagtgtgtccaagggccatgccaacatc
ttcaccctgctgggggagcttggcgccatgcacatgctcagtagcatccagaaggcagct
ggtgacatttttgacatagtctctggccaagcagttgtggaccatcccctgtgtgaagaa
tgcaccgacagtcttttagagcagctggacatccagctcgctctcacagaagctgacagt
cagaactaccaacgctgcctggagaccggggagctggcgaccagcgaggacgaggcggcg
gcgctgcgggcggagctgcgggacctggagctggaggaggccaggctggtgcaggagctg
gaggatgtggacaggaacaatgcaagagcagcggcggatctccaggcagcccaggcagag
gctgcggagctggaccagcaggagaggcagcactacagggactacagtgccttgaagcgg
cagcagctggaactgcttgatcagctggggaacgtggagaaccagctgcagtatgccagg
gtccagagggaccggctgaaggaaatcaactgtttcaccgccacgtttgagatctgggtg
gagggccccttgggcgtcatcaataacttcaggttgggccgcctccccactgtccgtgtg
ggctggaatgagattaacactgcctggggacaggcggccttgctgctccttaccctggcc
aatacaattggactgcagtttcagaggtatcgactcatcccctgcggaaaccattcgtat
ctgaagtctttaacagatgaccgcactgagctgccgttgttctgttatggggggcaggat
gttttcctcaataacaagtatgaccgcgcgatggtggccttcctggactgcatgcagcag
ttcaaggaagaggctgagaagggtgagctgggcctctctctgccctacgggatccaggtg
gagacaggcctgatggaggacgttggcggccgaggggaatgctattccatcagaacccat
ctgaacacgcaggagctgtggacaaaggcactcaagttcatgcttataaatttcaagtgg
agtctcatctgggttgcctcaaggtatcaaaagtag
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