Homo sapiens (human): 4717
Help
Entry
4717 CDS
T01001
Symbol
NDUFC1, KFYI
Name
(RefSeq) NADH:ubiquinone oxidoreductase subunit C1
KO
K03967
NADH dehydrogenase (ubiquinone) 1 subunit C1
Organism
hsa
Homo sapiens (human)
Pathway
hsa00190
Oxidative phosphorylation
hsa01100
Metabolic pathways
hsa04714
Thermogenesis
hsa04723
Retrograde endocannabinoid signaling
hsa04932
Non-alcoholic fatty liver disease
hsa05010
Alzheimer disease
hsa05012
Parkinson disease
hsa05014
Amyotrophic lateral sclerosis
hsa05016
Huntington disease
hsa05020
Prion disease
hsa05022
Pathways of neurodegeneration - multiple diseases
hsa05208
Chemical carcinogenesis - reactive oxygen species
hsa05415
Diabetic cardiomyopathy
Module
hsa_M00147
NADH dehydrogenase (ubiquinone) 1 beta subcomplex
Network
nt06460
Alzheimer disease
nt06463
Parkinson disease
nt06464
Amyotrophic lateral sclerosis
nt06466
Pathways of neurodegeneration
Element
N00995
Electron transfer in Complex I
N00997
Mutation-caused aberrant Abeta to electron transfer in Complex I
N01042
Mutation-caused aberrant SNCA to electron transfer in Complex I
N01043
Mutation-inactivated PINK1 to electron transfer in Complex I
N01044
MPP+ to electron transfer in Complex I
N01045
Rotenone to electron transfer in Complex I
N01136
Mutation-caused aberrant TDP43 to electron transfer in Complex I
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09102 Energy metabolism
00190 Oxidative phosphorylation
4717 (NDUFC1)
09150 Organismal Systems
09156 Nervous system
04723 Retrograde endocannabinoid signaling
4717 (NDUFC1)
09159 Environmental adaptation
04714 Thermogenesis
4717 (NDUFC1)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
4717 (NDUFC1)
09164 Neurodegenerative disease
05010 Alzheimer disease
4717 (NDUFC1)
05012 Parkinson disease
4717 (NDUFC1)
05014 Amyotrophic lateral sclerosis
4717 (NDUFC1)
05016 Huntington disease
4717 (NDUFC1)
05020 Prion disease
4717 (NDUFC1)
05022 Pathways of neurodegeneration - multiple diseases
4717 (NDUFC1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
4717 (NDUFC1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
4717 (NDUFC1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
NADH_dh_m_C1
Motif
Other DBs
NCBI-GeneID:
4717
NCBI-ProteinID:
NP_001171915
OMIM:
603844
HGNC:
7705
Ensembl:
ENSG00000109390
UniProt:
O43677
Structure
PDB
LinkDB
All DBs
Position
4:complement(139289917..139302551)
Genome browser
AA seq
76 aa
AA seq
DB search
MAPSALLRPLSRLLAPARLPSGPSVRSKFYVREPPNAKPDWLKVGFTLGTTVFLWIYLIK
QHNEDILEYKRRNGLE
NT seq
231 nt
NT seq
+upstream
nt +downstream
nt
atggcgccgtccgccttgctgcgtcccctttcccggctgctggcccccgccaggctcccg
agcggcccttcagtgcgatcaaagttctacgtgcgagagccgccgaatgccaaacctgac
tggctgaaagttgggttcaccttgggcaccactgtcttcttgtggatctatctcatcaaa
caacacaatgaagatattttagagtacaaaagaagaaatgggctggaataa
DBGET
integrated database retrieval system