Homo sapiens (human): 7846
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Entry
7846 CDS
T01001
Symbol
TUBA1A, B-ALPHA-1, LIS3, TUBA3
Name
(RefSeq) tubulin alpha 1a
KO
K07374
tubulin alpha
Organism
hsa
Homo sapiens (human)
Pathway
hsa04145
Phagosome
hsa04210
Apoptosis
hsa04530
Tight junction
hsa04540
Gap junction
hsa04814
Motor proteins
hsa05010
Alzheimer disease
hsa05012
Parkinson disease
hsa05014
Amyotrophic lateral sclerosis
hsa05016
Huntington disease
hsa05020
Prion disease
hsa05022
Pathways of neurodegeneration - multiple diseases
hsa05130
Pathogenic Escherichia coli infection
hsa05132
Salmonella infection
Network
nt06180
Pathogenic Escherichia coli
nt06181
Salmonella
nt06460
Alzheimer disease
nt06461
Huntington disease
nt06463
Parkinson disease
nt06464
Amyotrophic lateral sclerosis
nt06465
Prion disease
nt06466
Pathways of neurodegeneration
nt06515
Regulation of kinetochore-microtubule interactions
Element
N00976
Retrograde axonal transport
N00977
Mutation-caused aberrant Htt to retrograde axonal transport
N00978
Anterograde axonal transport
N00979
Mutation-caused aberrant Htt to anterograde axonal transport
N01018
Mutation-caused aberrant Abeta to anterograde axonal transport
N01055
Mutation-caused aberrant SNCA to anterograde axonal transport
N01158
Mutation-caused aberrant DCTN1 to retrograde axonal transport
N01285
Microtubule-RHOA signaling pathway
N01286
Escherichia EspG to Microtubule-RHOA signaling pathway
N01295
Rab7-regulated microtubule minus-end directed transport
N01297
Arl8-regulated microtubule plus-end directed transport
N01298
Salmonella SifA to microtubule plus-end directed transport
N01299
Salmonella PipB2 to microtubule plus-end directed transport
N01403
Zn to anterograde axonal transport
N01414
Iron to anterograde axonal transport
N01535
Kinetochore microtubule attachment
N01544
Microtubule nucleation
N01547
Kinetochore fiber organization
N01549
Branching microtubule nucleation
N01553
Promotion of microtubule growth
N01561
Microtubule depolymerization
N01562
Microtubule depolymerization at the minus ends
Disease
H00268
Lissencephaly
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09141 Transport and catabolism
04145 Phagosome
7846 (TUBA1A)
09143 Cell growth and death
04210 Apoptosis
7846 (TUBA1A)
09144 Cellular community - eukaryotes
04530 Tight junction
7846 (TUBA1A)
04540 Gap junction
7846 (TUBA1A)
09142 Cell motility
04814 Motor proteins
7846 (TUBA1A)
09160 Human Diseases
09171 Infectious disease: bacterial
05130 Pathogenic Escherichia coli infection
7846 (TUBA1A)
05132 Salmonella infection
7846 (TUBA1A)
09164 Neurodegenerative disease
05010 Alzheimer disease
7846 (TUBA1A)
05012 Parkinson disease
7846 (TUBA1A)
05014 Amyotrophic lateral sclerosis
7846 (TUBA1A)
05016 Huntington disease
7846 (TUBA1A)
05020 Prion disease
7846 (TUBA1A)
05022 Pathways of neurodegeneration - multiple diseases
7846 (TUBA1A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
hsa03019
]
7846 (TUBA1A)
03036 Chromosome and associated proteins [BR:
hsa03036
]
7846 (TUBA1A)
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
hsa04812
]
7846 (TUBA1A)
04147 Exosome [BR:
hsa04147
]
7846 (TUBA1A)
Messenger RNA biogenesis [BR:
hsa03019
]
Eukaryotic type
mRNA surveillance and transport factors
mRNA cycle factors
P-body specific factors
7846 (TUBA1A)
Chromosome and associated proteins [BR:
hsa03036
]
Eukaryotic type
Centrosome formation proteins
Microtubules and associated factors
Other tubulins
7846 (TUBA1A)
Cytoskeleton proteins [BR:
hsa04812
]
Eukaryotic cytoskeleton proteins
Microtubules
Tubulins
7846 (TUBA1A)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
7846 (TUBA1A)
Exosomal proteins of other body fluids (saliva and urine)
7846 (TUBA1A)
Exosomal proteins of colorectal cancer cells
7846 (TUBA1A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Tubulin
Tubulin_C
Tubulin_3
Motif
Other DBs
NCBI-GeneID:
7846
NCBI-ProteinID:
NP_001257328
OMIM:
602529
HGNC:
20766
Ensembl:
ENSG00000167552
UniProt:
Q71U36
Structure
PDB
LinkDB
All DBs
Position
12:complement(49184795..49189080)
Genome browser
AA seq
451 aa
AA seq
DB search
MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK
HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD
RIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA
VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA
SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN
QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPP
TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE
AREDMAALEKDYEEVGVDSVEGEGEEEGEEY
NT seq
1356 nt
NT seq
+upstream
nt +downstream
nt
atgcgtgagtgcatctccatccacgttggccaggctggtgtccagattggcaatgcctgc
tgggagctctactgcctggaacacggcatccagcccgatggccagatgccaagtgacaag
accattgggggaggagatgattccttcaacaccttcttcagtgagacgggggctggcaag
catgtgccccgggcagtgtttgtagacttggaacccacagtcattgatgaagttcgcact
ggcacctaccgccagctcttccaccctgagcaacttatcacaggcaaagaagatgctgcc
aataactatgcccgagggcactacaccattggcaaggagatcattgacctcgtgttggac
cgaattcgcaagctggccgaccagtgcacgggtctccagggcttcttggttttccacagc
tttggtgggggaactggttctgggttcacctcgctgctcatggaacgtctctcagttgat
tatggcaagaagtccaagctggagttctctatttacccggcgccccaggtttccacagct
gtagttgagccctacaactccatcctcaccacccacaccaccctggagcactctgattgt
gccttcatggtagacaatgaggccatctatgacatctgtcgtagaaacctcgatattgag
cgtccaacctatactaacctgaataggttaataggtcaaattgtgtcctccatcactgct
tccctgagatttgatggagccctgaatgttgacctgacagaattccagaccaacctggtg
ccctatccccgcatccacttccctctggccacatatgcccctgtcatctctgctgagaaa
gcctaccatgaacagctttctgtagcagagatcaccaatgcttgctttgagccagccaac
cagatggtgaaatgtgaccctcgccatggtaaatacatggcttgctgcctgttgtaccgt
ggtgacgtggttcccaaagatgtcaatgctgccattgccaccatcaagaccaagcgtacc
atccagtttgtggattggtgccccactggcttcaaggttggcatcaactaccagcctccc
actgtggtgcctggtggagacctggccaaggtacagagagctgtgtgcatgctgagcaac
accacagccattgctgaggcctgggctcgcctggaccacaagtttgacctgatgtatgcc
aaacgtgcctttgttcactggtacgttggggaggggatggaggaaggtgagttttcagag
gcccgtgaggacatggctgcccttgagaaggattatgaggaggttggtgtggattctgtt
gaaggagagggtgaggaagaaggagaggaatactaa
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