KEGG   VARIANT: 1557v1
Entry
1557v1                      Variant                                
Name
CYP2C19 polymorphism for poor drug metabolism
Gene
CYP2C19  cytochrome P450 family 2 subfamily C member 19 [KO:K17721]
Organism
hsa_var Human gene variants (Homo sapiens)
Variation
*2 mutation P227= (synonymous codon)
ClinVar: 16897
dbSNP: rs4244285
Variation
*3 mutation W212* (stop codon)
ClinVar: 16899
dbSNP: rs4986893
Reference
PMID:25974703
  Authors
Hicks JK, Bishop JR, Sangkuhl K, Muller DJ, Ji Y, Leckband SG, Leeder JS, Graham RL, Chiulli DL, LLerena A, Skaar TC, Scott SA, Stingl JC, Klein TE, Caudle KE, Gaedigk A
  Title
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and CYP2C19 Genotypes and Dosing of Selective Serotonin Reuptake Inhibitors.
  Journal
Clin Pharmacol Ther 98:127-34 (2015)
DOI:10.1002/cpt.147
Reference
PMID:24134832
  Authors
Gharani N, Keller MA, Stack CB, Hodges LM, Schmidlen TJ, Lynch DE, Gordon ES, Christman MF
  Title
The Coriell personalized medicine collaborative pharmacogenomics appraisal, evidence scoring and interpretation system.
  Journal
Genome Med 5:93 (2013)
DOI:10.1186/gm499
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