Halomonas aestuarii: BOX17_15050
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Entry
BOX17_15050 CDS
T04554
Name
(GenBank) 3-methyl-2-oxobutanoate dehydrogenase
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
hsi
Halomonas aestuarii
Pathway
hsi00280
Valine, leucine and isoleucine degradation
hsi00640
Propanoate metabolism
hsi00785
Lipoic acid metabolism
hsi01100
Metabolic pathways
hsi01110
Biosynthesis of secondary metabolites
hsi01210
2-Oxocarboxylic acid metabolism
Module
hsi_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
hsi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
BOX17_15050
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
BOX17_15050
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
BOX17_15050
Enzymes [BR:
hsi01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
BOX17_15050
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Motif
Pfam:
E1_dh
Transketolase_N
DUF4440
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
APE32150
UniProt:
A0A1J0VJG2
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Position
3267514..3268728
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AA seq
404 aa
AA seq
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MTTTPDIHAPTFLAGDEFSIPTFRLLKQDGSLHEGATAPELEQDKALAIYRAMVATRVLD
ERMLAAQRQGRLSFYMQCTGEEAAVVGATAALDDADMIMAQYREQGALVYRGFTFDEFMN
QLFGNELDYGKGRQMPIHYGSRKLHYMTISSPLATQIPQATGYAYGQKLAGDGLCTTVFF
GEGAASEGDFHAALNMAAVHEVPVIFFCRNNGYAISTPSIEQFAADGVAPRAFGYRMHVI
RVDGNDILAVYSATREARRIAVEHNQPVLIEAMSYRLAAHSSSDDPSGYRSKKEEEAWRD
KDPILRMQRWLIDLGWWSEEEEKALQESLRREVLETMKRAEKRPPPPLDSLVTDVYADVT
PELQRQLDSLKRHIRQYPEAYPKGASSLDPDVRAGDDVAAKGED
NT seq
1215 nt
NT seq
+upstream
nt +downstream
nt
atgacaacaacaccggatatccacgcgccgacgttcctggccggcgacgagttcagcatt
cccaccttccgcctgctgaagcaggacggcagcctccatgagggcgccacggcgccggag
ctcgagcaggacaaggccctggccatctatcgcgccatggtcgccacccgcgtgctcgac
gagcgcatgctggccgcccagcgtcagggccgtctctccttctacatgcagtgtaccggc
gaggaggccgcggtggtcggcgccacagcggccctcgacgacgccgacatgatcatggcc
cagtaccgcgagcagggggccctggtctatcgcggcttcaccttcgacgagttcatgaac
cagctgttcggcaacgagctggactacggcaaggggcgccagatgccgatccactatggg
tcgcgcaagctccactacatgaccatctcctcgccgctggcgacccagatcccccaggcc
accggctatgcctatggccagaagctcgccggcgacggcctgtgcaccaccgtcttcttc
ggcgagggggccgcctcggagggcgacttccacgccgccctgaacatggccgcggtgcac
gaggtgccggtcatcttcttctgtcgcaacaacggctacgccatctcgaccccctccatc
gagcagttcgccgccgacggcgtggccccccgggccttcggctaccgcatgcacgtgatc
cgggtcgacggcaacgacatcctggcggtctactcggccacccgggaggcgcggcgcatc
gccgtggagcacaaccagccggtgctgatcgaggccatgagctaccgcctggccgcccac
tcctcctcggacgacccctccggctatcgctcgaagaaggaggaggaggcctggcgcgac
aaggatcccatcctgcgcatgcagcgctggctcatcgacctgggctggtggagcgaggag
gaggagaaggccctccaggagagcctgcgccgggaggtgctggagaccatgaagcgggcc
gagaagcgtccgccgccgcccctggacagcctggtgaccgatgtctacgccgatgtgacc
cccgagctgcagcgtcagctcgactccctgaaacgccacattcgccagtacccggaggcc
tacccgaagggagcgagctccctggacccggacgtgcgtgccggggacgacgtcgcggcc
aagggagaggactga
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