Isoptericola variabilis: Isova_0253
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Entry
Isova_0253 CDS
T01520
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
iva
Isoptericola variabilis
Pathway
iva00280
Valine, leucine and isoleucine degradation
iva00640
Propanoate metabolism
iva00785
Lipoic acid metabolism
iva01100
Metabolic pathways
iva01110
Biosynthesis of secondary metabolites
iva01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
iva00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
Isova_0253
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
Isova_0253
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Isova_0253
Enzymes [BR:
iva01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
Isova_0253
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
AEG43057
UniProt:
F6FSB6
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All DBs
Position
266476..267636
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AA seq
386 aa
AA seq
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MKNDATGGSDVAPADVTPLVQLVAPDGSRVVEADNAVFRERVAHLTVEDLRAMYRDMALT
RRFDDEATALQRQGELALYAQSRGQEAAQVGSGRALAGQDYVFPSYREHGVLHVRGVDPV
DRLRLYRGEDHGGWDPNEHNVHLYTLVIGSHALHATGYAMGLQRDGLVGTGDAARDTAVV
TYFGDGATSQGDVNEALVFAAVNNAPVVFFCQNNQWAISEPTTKQSRVPIYKRGEGFGVP
SVRVDGNDVLACYAVTAEALERAHSGGGPTFVEAYTYRMGAHTTSDDPTRYRDRAEEEHW
RRRDPLERLEALLRAEGGWDEEWAAALQAEADAYGERLRDGVRALGAPPAETMFDNVYAT
DHAQVTAERAWFREYEAATAGEEVAR
NT seq
1161 nt
NT seq
+upstream
nt +downstream
nt
gtgaagaacgacgccaccggcgggtccgacgtcgcacccgcggacgtcacgcccctcgtc
cagctcgtcgcgcccgacggcagccgcgtcgtcgaagccgacaacgccgtgttccgcgag
cgcgtcgcgcacctcaccgtcgaggacctgcgcgcgatgtaccgcgacatggccctcacc
cggaggttcgacgacgaggccaccgccctgcagcgccagggcgagctcgcgctctacgcg
cagagccgcggccaggaggctgcccaggtcgggtcgggccgcgcgctcgccggccaggac
tacgtctttcccagctaccgcgagcacggcgtgctgcacgtgcgcggcgtcgaccccgtc
gaccggctgcgcctgtaccgcggcgaggaccacggcggctgggacccgaacgagcacaac
gtgcacctgtacacgctcgtcatcgggtcgcacgcgctgcacgccacgggctacgcgatg
gggctgcagcgcgacgggctcgtcggcacgggcgacgccgcgcgcgacaccgcggtcgtc
acgtacttcggcgacggcgccacgagccagggcgacgtcaacgaggcgctcgtcttcgcg
gccgtgaacaacgcgccggtcgtgttcttctgccagaacaaccagtgggcgatctccgag
ccgaccacgaagcagtcgcgcgtgccgatctacaagcgcggcgagggcttcggcgtgccg
agcgtgcgggtcgacggcaacgacgtgctggcctgctacgcggtcaccgccgaggcgctc
gagcgcgcgcactccggcggcgggccgacgttcgtcgaggcgtacacctaccgcatgggc
gcgcacacgacgtcggacgacccgacgcgctaccgcgaccgggccgaggaggagcactgg
cgccgccgcgacccgctcgagcggctcgaggcgctgctgcgcgccgagggcggctgggac
gaggaatgggctgccgcgctgcaggccgaggccgacgcgtacggcgagcgtctgcgcgac
ggcgtccgcgcgctcggcgccccgccggccgagaccatgttcgacaacgtctacgcgacc
gaccacgcgcaggtgaccgccgagcgcgcctggttccgcgagtacgaggccgcgacggcc
ggcgaggaggtcgcccggtga
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