Isoptericola variabilis: Isova_1170
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Entry
Isova_1170 CDS
T01520
Name
(GenBank) FolC bifunctional protein
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
iva
Isoptericola variabilis
Pathway
iva00790
Folate biosynthesis
iva01100
Metabolic pathways
iva01240
Biosynthesis of cofactors
Module
iva_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
iva00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
Isova_1170
Enzymes [BR:
iva01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
Isova_1170
6.3.2.17 tetrahydrofolate synthase
Isova_1170
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
AEG43940
UniProt:
F6FRT9
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Position
1283379..1284779
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AA seq
466 aa
AA seq
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MSAAKKGSGKAAREAAEDAVAREQLKEVYAHIMSRAPEHDIDPTLARVQRVLELLGDPQH
AFRSIHLTGTNGKSSTARMTERLVREHGLRTGLFTSPHLTSVTERIQVDGEPLSAARFVE
VWEDVAPYVGVADRESAEAGGPPLSFFEVLTVMAIAAFADAPVDVAVIEVGMGGRWDSTN
VVDGEVAILTPVGIDHERWLGSTLEEIATEKSGIVKERATVVSALQAPEVDEILRARASD
VSARLLREGVELEVAGRQLAVGGQLVNLRTPAGLYTDVPVPLHGEHQAHNALLALAAVEQ
LLGGRTLDGAVVEAAFADVTAPGRLELVRSSPTVLVDAAHNPHGAEALVAALEEAFGFRT
LVGVVAVMADKDAEGLLATLEPTLASVVVTRNSSPRSADPHDLAEVAREVFGEDRVQVTE
RLDEAIQVATDLAERDDAVGVGTGTGVLVTGSVITVADARILLGRG
NT seq
1401 nt
NT seq
+upstream
nt +downstream
nt
gtgagcgccgcgaagaagggctcgggcaaggccgcgcgcgaggcggccgaggacgccgtc
gcgcgcgagcagctcaaggaggtctacgcgcacatcatgtcgcgtgcccccgagcacgac
atcgacccgacgctcgcgcgcgtccagcgcgtcctcgagctgctcggcgacccgcagcac
gcgttccgctcgatccacctcacgggcacgaacggcaagtcgtcgaccgcgcgcatgacc
gagcgcctcgtgcgcgagcacgggctgcgcacgggcctgttcacgtcgccgcacctgacg
agcgtgaccgagcggatccaggtcgacggcgagccgctgagcgcggcgcgcttcgtcgag
gtgtgggaggacgtcgcgccctacgtcggcgtcgcggaccgcgagtcggccgaggccggc
ggcccgccgctgagcttcttcgaggtgctcacggtcatggcgatcgcggcgttcgcggac
gcgcccgtcgacgtcgcggtgatcgaggtcggcatgggcggccggtgggactccacgaac
gtcgtcgacggcgaggtcgcgatcctcaccccggtcggcatcgaccacgagcgctggctc
ggctcgacgctcgaggagatcgccacggagaagtcgggcatcgtcaaggagcgcgcgacc
gtggtcagcgcgctgcaggcgcccgaggtcgacgagatcctgcgcgcccgggcgtccgac
gtctccgcgcggctgctgcgcgagggcgtcgagctcgaggtcgcgggccgtcagctcgcc
gtcggcggccagctcgtgaacctgcgcacgcccgccggcctctacaccgacgtcccggtg
ccgctgcacggcgagcaccaggcgcacaacgcgctgctcgccctcgccgcggtcgagcag
ctgctcggcggacggaccctcgacggggccgtcgtcgaggccgcgttcgccgacgtcacc
gcgcccgggcggctcgagctcgtgcggtcgagcccgaccgtgctcgtcgacgccgcgcac
aacccgcacggcgccgaggcgctcgtcgcggcgctcgaggaggcgttcggcttccgcacg
ctcgtgggcgtcgtggccgtcatggccgacaaggacgccgaggggctgctcgccacgctc
gagccgacgctcgcgtccgtcgtcgtgacccggaactcgtcgccgcgctcggcggacccg
cacgacctcgccgaggtcgcgcgcgaggtgttcggcgaggaccgcgtgcaggtgacggag
cgcctcgacgaggcgatccaggtcgcgaccgacctcgccgagcgcgacgacgccgtcggc
gtcggcaccggcacgggcgtgctggtcaccggctcggtcatcaccgtcgccgacgcgcgg
atcctcctgggccgtggctga
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